Search clinical trials for: 0.25g SRT2104

Total 625 results

Sirtris, a GSK Company
GlaxoSmithKline

Completed

A Clinical Study to Assess the Effect of Food and Gender on the Pharmacokinetics of SRT2104 Administered as an Oral Suspension or Capsule Formulation to Normal Healthy Volunteers

Diabetes Mellitus, Type 2

United Kingdom
GlaxoSmithKline

Completed

Clinical Study to Assess the Effects of SRT2104 and Prednisolone on Biomarkers in Blood in Healthy Volunteers

Pulmonary Disease, Chronic Obstructive

United Kingdom
Sirtris, a GSK Company

Completed

A Study to Assess the Relative Bioavailability of New Oral Formulations of SRT2104 in Healthy Male Volunteers

Psoriasis

United States
GlaxoSmithKline

Completed

Effect of SRT2104 on Endotoxin-induced Inflammation

Sepsis

Netherlands
Sirtris, a GSK Company
GlaxoSmithKline

Completed

A Clinical Study to Evaluate the Pharmacokinetics and the Absolute Bioavailability of SRT2104 Given as a 250mg Oral Suspension and Intravenous Microdose of 100 µg Carbon-14 Radio-labeled SRT2104 in Healthy Male Subjects

Diabetes Mellitus, Type 2

United Kingdom
Sirtris, a GSK Company
GlaxoSmithKline

Completed

Clinical Study to Assess the Safety and Pharmacokinetics of SRT2104 in Type 2 Diabetic Human Subjects

Diabetes Mellitus, Type 2

Bulgaria, Estonia, Russian Federation, Ukraine, United Kingdom, Hungary, Poland, Romania
GlaxoSmithKline

Completed

Clinical Study to Assess the Pharmacokinetics, Safety and Tolerability of SRT2104 Administered to Normal Healthy Male Volunteers

Diabetes Mellitus, Type 2

United Kingdom
GlaxoSmithKline

Completed

A Clinical Study to Assess the Safety, Tolerability, and Activity of Oral SRT2104 Capsules Administered for 28 Days to Subjects With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Germany
Sirtris, a GSK Company
GlaxoSmithKline

Completed

Study of the Clinical Activity, Safety, and Tolerability of SRT2104 in Subjects With Moderate to Severe Plaque-Type Psoriasis

Psoriasis

United States
GlaxoSmithKline

Completed

A Clinical Study to Assess the Safety, Tolerability and Pharmacokinetics of Oral SRT2104 Capsules Administered to Healthy Elderly Subjects for 28 Days

Atrophy, Muscular

United Kingdom
Sirtris, a GSK Company
GlaxoSmithKline

Completed

A Clinical Trial to Assess the Safety of Oral SRT2104 and Its Effects on Vascular Dysfunction in Otherwise Healthy Cigarette Smokers and Subjects With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United Kingdom
GlaxoSmithKline

Withdrawn

A Clinical Study to Assess the Effects of SRT2104 Upon Immobilization-Induced Skeletal Muscle Atrophy in Healthy Human Volunteers

Healthy Volunteer | Atrophy, Muscular
Sirtris, a GSK Company
GlaxoSmithKline

Completed

A Clinical Study to Assess the Safety and Pharmacokinetics of SRT2104 in Normal Healthy Male Volunteers

Diabetes Mellitus, Type 2 | Healthy Volunteer

United Kingdom
Sirtris, a GSK Company
GlaxoSmithKline

Completed

A Phase 1b Study to Assess the Safety and Anti-inflammatory Effects of Two Different Doses of SRT2104 in Patients With Ulcerative Colitis

Colitis, Ulcerative

United States
Nestlé

Withdrawn

Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of CDX 6114 in PKU Patients

Phenylketonurias
Seoul National University Hospital

Unknown

Mannitol Brain Relaxation Effect (MANNITOL)

Supratentorial Neoplasms

Korea, Republic of
Hanyang University Seoul Hospital

Completed

The Manikin Study of Chest Compression With One Accelerometer Feedback Device

Cardiac Arrest

Korea, Republic of
Chong Kun Dang Pharmaceutical

Completed

A Clinical Study to Compare the Pharmacokinetic Characteristics of CKD-395 0.25/750 mg in Healthy Male Volunteers

Diabetes Mellitus, Type II

Korea, Republic of
Andrew J. Armstrong, MD

Completed

The CATCH Prostate Cancer Trial: Cabazitaxel And Tasquinimod in Men With Prostate Cancer (CATCH)

Prostate Cancer

United States
Novartis Pharmaceuticals

Completed

A Trial to Evaluate the Safety, Local Tolerability, Pharmacokinetics and Pharmacodynamics of LDE225 on Skin Basal Cell Carcinomas in Gorlin Syndrome Patients

Treatment for Basal Cell Carcinomas (BCCs) in Gorlin Syndrome Patients

Austria, Switzerland
Pfizer

Completed

Safety Study of FSME-IMMUN NEW in Healthy Children and Adolescents Aged 1 to 15 Years

Tick-borne Encephalitis

Austria, Germany, Poland
Hanmi Pharmaceutical Company Limited

Completed

A Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of HCP1303 Capsules

Benign Prostatic Hyperplasia
Assiut University

Completed

Spinal Versus Caudal Analgesia After Pediatric Infra-umbilical Surgery (ITVSEpidural)

Pain, Postoperative

Egypt
Lexicon Pharmaceuticals

Completed

Study to Evaluate the Safety, Tolerability, and Efficacy of LX7101 in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Primary Open-angle Glaucoma

United States
Tarsus Pharmaceuticals, Inc.

Completed

Safety and Efficacy of TP-03 for the Treatment of Demodex Blepharitis (Saturn-1)

Blepharitis

United States
Kala Pharmaceuticals, Inc.

Completed

Safety and Efficacy of KPI-121 in Subjects With Postsurgical Inflammation (Hawaii-1)

Ocular Infections, Irritations and Inflammations

United States
Allecra
Medpace, Inc.

Completed

Cefepime/AAI101 Phase 2 Study in Hospitalized Adults With cUTI

Urinary Tract Infections

Hungary, Czechia, Poland, Slovakia, Ukraine
JW Pharmaceutical

Completed

Phase 2 Study of URC102 to Assess the Efficacy and Safety in Gout Patients

Hyperuricemia | Gout

Korea, Republic of
Rush University Medical Center

Completed

Delays to Influence Snack Choice (DISC)

Food Choice

United States
St. Justine's Hospital
Rennes University Hospital

Completed

Cardio-respiratory Events and Inflammatory Response After Primary Immunization in Preterm Infants

Complication Due to Immunization
Gruppo Italiano Malattie EMatologiche dell'Adulto

Active, not recruiting

Venetoclax Add in Combination With Fludarabine, Cyratabine and Idarubicine in Induction for Acute Myelid Leukemia (V-FIRST)

Acute Myeloid Leukemia

Italy
Thymon, LLC

Completed

Clinical Study of TUTI-16 in HIV-1 Infected and Uninfected Subjects (THYMON-10001)

HIV Infections

United States
Zhejiang Cancer Hospital

Recruiting

Ciprofol EC50 for Inducing Loss of Consciousness in Elderly Patients

Elderly Patients

China
The University of Hong Kong

Not yet recruiting

GLP-1 Receptor Agonist for Reduction of Myocardial Injury After Non-cardiac Surgery (GLUMINS)

Myocardial Injury

China
Santalis Pharmaceuticals, Inc.
The University of Texas Health Science Center at San Antonio

Completed

A Trial of a Botanical Drug Containing East Indian Sandalwood Oil (EISO) for the Treatment of Oral Mucositis

Oral Mucositis

United States
Kala Pharmaceuticals, Inc.

Completed

Safety and Efficacy of KPI-121 Compared to Placebo in Subjects With Dry Eye Disease (STRIDE 2)

Dry Eye Syndromes | Keratoconjunctivitis Sicca

United States
Kala Pharmaceuticals, Inc.

Completed

Exploratory Study of KPI-121 Effect on Intra- or Subretinal Fluid Due to Retinal Vein Occlusion/Diabetic Macular Edema (Molokini)

Diabetic Macular Edema | Retinal Vein Occlusion

United States
AsclepiX Therapeutics, Inc.

Terminated

Safety and Bioactivity of AXT107 in Subjects With Neovascular Age-Related Macular Degeneration (SHASTA)

Neovascular Age-Related Macular Degeneration (nAMD)

United States
Takeda

Completed

Phase 1/2 Study of TAK-850 Intramuscular Injection in Healthy Pediatric Participants

Influenza Infection

Japan
AsclepiX Therapeutics, Inc.

Terminated

Safety and Bioactivity of AXT107 in Subjects With Diabetic Macular Edema (CONGO)

Diabetic Macular Edema (DME)

United States
BenevolentAI Bio

Completed

A First-in-Human PoC Study With BEN2293 in Patients With Mild to Moderate Atopic Dermatitis

Atopic Dermatitis

United Kingdom
Kala Pharmaceuticals, Inc.

Completed

Safety and Efficacy of KPI-121 in Subjects With Dry Eye Disease (STRIDE 1)

Dry Eye Syndromes | Keratoconjunctivitis Sicca

United States
Gamaleya Research Institute of Epidemiology and...

Completed

Evaluation of the Safety and Immunogenicity of the Recombinant Subunit Vaccine "GamTBvac" Against the Tuberculosis. (GamTBvac)

Tuberculosis

Russian Federation
QED Therapeutics, Inc.

Enrolling by invitation

A Study to Evaluate the Efficacy and Safety of Infigratinib in Children and Adolescents With Achondroplasia (PROPEL3)

Achondroplasia

Australia, United States, Argentina, Canada, France, Germany, Italy, Norway, Singapore, Spain, United Kingdom
Kala Pharmaceuticals, Inc.

Completed

Safety and Efficacy of KPI-121 in Subjects With Dry Eye Disease (Kauai)

Dry Eye Syndromes | Keratoconjunctivitis Sicca

United States
Pfizer

Completed

Tick-Borne Encephalitis (TBE) Seropersistence After First Booster and Response to a Second Booster in Children, Adolescents and Young Adults (Follow-Up to Study 700401)

Encephalitis, Tick-Borne

Austria, Germany, Poland
Aldeyra Therapeutics, Inc.

Completed

A Multi-Center, Randomized, Double-Masked, Parallel-Group, Vehicle-Controlled, Clinical Trial of Reproxalap to Assess the Safety and Efficacy in Subjects With Dry Eye Disease

Dry Eye

United States
Weill Medical College of Cornell University

Terminated

Marcaine Use in Laparoscopic Gynecological Surgery (Marcaine)

Post-operative Pain

United States
Cara Therapeutics, Inc.

Completed

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis (KARE)

Pruritus | Atopic Dermatitis

United States, Canada
Assiut University

Unknown

Omitting GnRH-antagonist Dose on the Day of Ovulation Trigger

Pituitary Downregulation

Egypt

3

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