Search clinical trials for: 11C-sarcosine

Total 2296 results

Astellas Pharma Inc

Completed

A Study to Assess the Systemic Disposition of ASP1585 After Administration of 14C-labeled Drug

Healthy | Pharmacokinetics of ASP1585

United States
Biomedical Radiation Sciences
Swedish Cancer Society

Completed

Exploratory Study of Breast Cancer With ABY025 (ABY0125)

Breast Cancer

Sweden
University of Utah

Completed

Multi-Tracer PET Assessment of Primary Brain Tumors

Cancer | Brain Tumors

United States
Neurocrine Biosciences
Takeda

Completed

A Study to Assess Absolute Bioavailability (ABA) of TAK-831 and to Characterize Mass Balance, Pharmacokinetics (PK), Metabolism, and Excretion of [14C]TAK-831 in Male Healthy Participants

Healthy Volunteers

United States
Pfizer

Completed

Study to Characterize Absorption, Distribution, Metabolism and Excretion of 14C PF-06651600 and to Evaluate the Absolute Oral Bioavailability and Fraction Absorbed of PF-06651600. (B7981011)

Healthy Volunteers

Netherlands
Bausch Health Americas, Inc.

Completed

Safety and Efficacy of IDP-118 Lotion in the Treatment of Plaque Psoriasis

Psoriasis

United States
Praxis Precision Medicines

Completed

A Clinical Trial of Adjunctive and Monotherapy PRAX-114 in Participants With Major Depressive Disorder

Major Depressive Disorder

United States, Australia
Galapagos NV

Completed

Evaluation of Mass Balance and Absolute Bioavailability of GLPG3667

Healthy

United Kingdom
University of Aarhus
Aarhus University Hospital

Terminated

Imaging With 11C-erlotinib PET/CT to Identify Responders to Erlotinib Treatment in NSCLC

Lung Cancer

Denmark
Assistance Publique - Hôpitaux de Paris
France Parkinson Association

Unknown

Measure of Microglial Activation in the Brain of Parkinson Disease Patients With PET (INFLAPARK)

Healthy Controls | Parkinson's Disease With LRRK2 Mutation | Parkinson's Disease Without LRRK2 Mutation

France
United Therapeutics

Completed

A Pharmacokinetic Substudy of the TDE-PH-304 Protocol

Pulmonary Arterial Hypertension

United States
Pfizer

Completed

A Study To Asses Mass Balance And Absolute Bioavailability Of 14C PF-06826647 In Healthy Male Participants

Healthy

Netherlands
Rahul Aggarwal
National Cancer Institute (NCI)

Terminated

Magnetic Resonance (MR) Imaging With Hyperpolarized Pyruvate (HP) (13C) in Castration-Resistant Prostate Cancer (MR)

Prostate Cancer

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Imaging of Radiolabeled White Blood Cells in Patients With Non-Hodgkin's Lymphoma

Lymphoma | Small Intestine Cancer

United States
Yale University
Janssen Scientific Affairs, LLC

Not yet recruiting

PET and MRI Imaging With Scopolamine at the Muscarinic M1 Receptor (emo_to2)

Muscarinic Receptor Occupancy

United States
Université de Sherbrooke

Completed

Pharmacological Activation of Brown Adipose Tissue Metabolism (GB6)

Type 2 Diabetes

Canada
Universitaire Ziekenhuizen KU Leuven

Completed

Synaptic Density and Progression of Huntington's Disease.

Huntington Disease

Belgium
GlaxoSmithKline

Completed

Exploratory Lapatinib (Positron Emission Tomography) PET Study in Subjects With Breast Cancer

Cancer

United Kingdom
Taiho Pharmaceutical Co., Ltd.

Recruiting

AB122 Platform Study

Gastric Cancer | Colorectal Cancer | Non-small Cell Lung Cancer | Pancreatic Ductal Adenocarcinoma | Alveolar Soft Part Sarcoma | Advanced or Metastatic Solid Tumor

Japan
Basilea Pharmaceutica

Completed

A Study to Assess the Mass Balance Recovery and Metabolite Profile & Identification of [14C]-APX001 in Healthy Males

Fungal Infection

United Kingdom
BioAge Labs, Inc.

Withdrawn

Study to Evaluate Efficacy and Safety of BGE-117 in Moderately to Severely Anemic Older Individuals After Major Hip Surgery

Acute Posthemorrhagic Anemia

Australia
ViiV Healthcare

Completed

Pharmacokinetics and Metabolism of 14 Carbon [14C]-GSK3640254

HIV Infections

United Kingdom
Takeda

Recruiting

An Absorption, Distribution, Metabolism, Excretion (ADME) Study of [14C]Subasumstat in Adults With Advanced or Metastatic Solid Tumors

Solid Tumors

Hungary
Optimal Health Research

Active, not recruiting

Diet Effect on Cancer Treatment Outcome

Cancer Breast | Cancer Prostate

United States, India
Boehringer Ingelheim

Completed

A Study in Healthy Men to Test How BI 1291583 is Taken up by the Body

Healthy

Netherlands
argenx

Active, not recruiting

A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP, an Autoimmune Disorder That Affects the Peripheral Nerves) (ADHERE+)

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

United States, Austria, Belgium, Bulgaria, China, Czechia, Denmark, France, Georgia, Germany, Israel, Italy, Japan, Netherlands, Poland, Russian Federation, Serbia, Spain, Ukraine, United Kingdom, Latvia, Romania, Taiwan, Turkey
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Evaluate ACT-132577 in Healthy Male Subjects

Healthy Subjects

Netherlands
Jazz Pharmaceuticals

Completed

"Twelve-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in Narcolepsy"

Narcolepsy

United States, France, Canada, Germany, Finland, Netherlands
Jazz Pharmaceuticals

Completed

"Twelve-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in OSA" (OSA)

Obstructive Sleep Apnea

United States, France, Canada, Germany, Netherlands
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Completed

Study to Investigate the Absorption, Metabolism and Excretion of [14C] Anlotinib in Patients With Advanced Cancer Patients

Advanced Solid Tumors

China
Astellas Pharma Global Development, Inc.

Completed

Study to Investigate the Absorption, Metabolism and Excretion of [14C] ASP2215 in Patients With Advanced Solid Tumors

Advanced Solid Tumors | Pharmacokinetics of 14C-labeled Gilteritinib

United States
Janssen Cilag N.V./S.A.

Completed

Study to Assess the Absorption, Metabolism and Excretion of 14C-JNJ-63623872 After a Single Dose in Healthy Male Participants

Healthy

Netherlands
Ascensia Diabetes Care

Completed

Evaluation of the A1CNow+ Test Kit

Diabetes

United States
Genfit
SGS Life Sciences, a division of SGS Belgium NV

Completed

Mass Balance Study of 14C-labelled GFT505 in Healthy Volunteers

Healthy

Belgium
Aptabio Therapeutics, Inc.

Recruiting

Study of APX-115 in Contrast Induced Acute Kidney Injury in Subjects Undergoing PCI

Contrast Induced Acute Kidney Injury

Korea, Republic of, United States
Amgen

Suspended

A Phase 1 Study Evaluating the Safety, Tolerability and Efficacy of AMG 119 in Subjects With RR SCLC

Small Cell Lung Cancer

United States
Amgen

Completed

A Study to Assess the Mass Balance Recovery (Absorption, Distribution, Metabolism and Excretion) of [14C]CCX168 in Healthy Participants

Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis

United States
Bristol-Myers Squibb

Completed

Study to Assess the Way the Body Absorbs, Distributes, Breaks Down and Eliminates Radioactive BMS-986278 in Healthy Male Participants

Healthy Volunteers

United States
Sihuan Pharmaceutical Holdings Group Ltd.

Unknown

Open-label Study to Assess the Absorption, Metabolism, Excretion, and Mass Balance of a Single Oral Dose of [14C]-20 mg/100 μCi Anaprazole Sodium Enteric-coated Capsule in Healthy Adult Male Subjects

Healthy Male Volunteers
Merrimack Pharmaceuticals

Completed

A Study of MM-111 in Patients With Advanced, Refractory Her2 Amplified, Heregulin Positive Cancers (Monotherapy)

Metastatic Breast Cancer | Her2 Amplified Solid Tumors

United States
Scynexis, Inc.
Inncelerex

Completed

ADME Study of [14C]-Ibrexafungerp in Healthy Male Subjects

Fungal Infection

United Kingdom
Université de Sherbrooke
Healthy Aging Research Network

Completed

Metabolism of Omega-3 and Omega-6 During Healthy Aging

Healthy Volunteers
Laboratorios Sophia S.A de C.V.

Withdrawn

Efficacy and Safety of PRO-118 Ophthalmic Solution in Allergic Conjunctivitis (PRO-118)

Conjunctivitis, Allergic | Seasonal Allergic Conjunctivitis | Ocular Itching | Ocular Allergy | Perennial Allergic Conjunctivitis

Mexico
Chang Gung Memorial Hospital
Ministry of Science and Technology, Taiwan

Recruiting

Hyperpolarized 13C Pyruvate MRI for Early Immune Evaluation in Cervical Cancer Patients at Baseline and CCRT Therapy

Cervical Cancer

Taiwan
University of Florida

Completed

13C-Pyruvate Breath Test (PBT)

Healthy

United States
Celgene

Completed

A Study to Evaluate the Absorption, Metabolism, and Excretion of Orally Administered [14C]-BMS-986368 in Healthy Male Participants

Healthy Volunteers

United States
DICE Therapeutics, Inc.

Completed

Mass Balance and Pharmacokinetics (PK) of [14C]-DC-806 in Healthy Male Participants

Healthy Volunteers

Netherlands
Cerevel Therapeutics, LLC

Completed

An Open-label Trial to Evaluate Mass Balance of Tavapadon at Steady State in Healthy Subjects

Healthy Subjects

United States
Ono Pharmaceutical Co. Ltd

Completed

Single-dose Study to Evaluate the Absolute Bioavailability and Mass Balance of ONO-5788 (ONO-5788-02)

Acromegaly

Netherlands
Susan Chang
National Cancer Institute (NCI)

Active, not recruiting

Hyperpolarized Carbon-13 (13C) Pyruvate Imaging in Patients With Glioblastoma

Glioblastoma Multiforme (GBM)

United States

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