Search clinical trials for: 13C-labeled Acetate

Total 6954 results

KU Leuven

Completed

Determination of the Bioavailability of Short Chain Fatty Acids in Healthy Humans

Short Chain Fatty Acids Bioavailability

Belgium
Hoffmann-La Roche

Completed

Mass Balance and Absolute Bioavailability Study of RO7049389 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Dysregulation of Glutamine Activity in the Pathogenesis of Multiple Myeloma

Monoclonal Gammopathy of Undetermined Significance | Plasma Cell Myeloma

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System

Parkinson's Disease | Atherosclerosis | Cardiomyopathy | Li-Fraumeni Syndrome | Cardiovascular Capacity

United States
University of Texas Southwestern Medical Center
National Cancer Institute (NCI); Howard Hughes Medical Institute

Recruiting

An Investigation of Kidney and Urothelial Tumor Metabolism in Patients Undergoing Surgical Resection and/or Biopsy

Kidney Cancer | Renal Cell Carcinoma | Urothelial Carcinoma | Hereditary Leiomyomatosis and Renal Cell Cancer | Metastatic Urothelial Carcinoma | Chromophobe Renal Cell Carcinoma | Papillary Renal Cell Carcinoma | HLRCC | Clear Cell Carcinoma | Metastatic Kidney Cancer | Fumarate Hydratase Deficiency | Succinate...

United States
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Recruiting

Investigating Targetable Metabolic Pathways Sustaining Pancreatic Cancer

Pancreatic Ductal Adenocarcinoma

United States
Wendell Yap, MD
University of Kansas Medical Center

No longer available

Clinical Management Decisions for Recurrent Prostate Cancer Patients Based on [11C]Acetate PET Scan

Prostate Cancer

United States
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate the Effect of ASP1707 on the Bodies of Healthy Male Subjects After a Single Dose of Radioactive ASP1707

Pharmacokinetics of ASP1707

United Kingdom
Spectrum Pharmaceuticals, Inc

Terminated

A Mass Balance and Pharmacokinetics Study of 14C-Labeled Poziotinib in Cancer Patients Suitable for Treatment With Poziotinib

Solid Tumor

United States
Poxel SA

Completed

Pharmacokinetics and Metabolism of (14C)-Labelled PXL770

Healthy

United Kingdom
Astellas Pharma Inc

Completed

A Study to Assess the Systemic Disposition of ASP1585 After Administration of 14C-labeled Drug

Healthy | Pharmacokinetics of ASP1585

United States
Columbia University

Terminated

Prehypertension Labeling (Tanya K23)

Prehypertension

United States
Emory University

Completed

Adolescent Idiopathic Scoliosis (AIS) Gold Standard for Blood Loss

Adolescent Idiopathic Scoliosis

United States
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Completed

Study to Investigate the Absorption, Metabolism and Excretion of [14C] Anlotinib in Patients With Advanced Cancer Patients

Advanced Solid Tumors

China
Astellas Pharma Global Development, Inc.

Completed

Study to Investigate the Absorption, Metabolism and Excretion of [14C] ASP2215 in Patients With Advanced Solid Tumors

Advanced Solid Tumors | Pharmacokinetics of 14C-labeled Gilteritinib

United States
Daniel Vaena

Completed

PET Acetate for Castrate-Resistant Prostate Cancer on Chemotherapy

Prostate Cancer | Castrate Resistant Prostate Cancer

United States
University of Alabama at Birmingham

Not yet recruiting

Understanding the Metabolic and Functional Derangement of Primary Mitral Regurgitation: a Feasibility Study Using Carbon 11(C-11) Acetate Cardiac Positron Emission Tomography Magnetic Resonance Imaging (PET-MRI)

Mitral Valve Regurgitation

United States
University of Pennsylvania

Terminated

11C-Acetate PET/CT Imaging As a Biomarker of Amyloid-Induced Neuroinflammation

Mild Cognitive Impairment

United States
Karolinska University Hospital
European Society of Intensive Care Medicine; Region Stockholm; The Scandinavian...

Recruiting

Lactate Kinetics in Septic Shock (LKISS)

Sepsis | Septic Shock

Sweden
Hospices Civils de Lyon

Completed

Investigation of Docosahexaenoic Acid (DHA) Metabolic Pathway in Human by Using 13C Labeled Molecules (AceDoPC)

Healthy Subject

France
University of Zurich

Completed

13C Trioctanoate Breath Test as a Measurement of Gastric Fat Volume Emptying (13CTriOBT)

Healthy

Switzerland
Massachusetts General Hospital

Terminated

11C Acetate Imaging Post Prostatectomy

Prostate Cancer

United States
Hoffmann-La Roche

Completed

A Study to Determine the Excretion Balance, Pharmacokinetics, Metabolism and Absolute Oral Bioavailability of a Single Oral Dose of [14C]-Labeled Idasanutlin and an Intravenous Tracer Dose of [13C]-Labeled Idasanutlin in a Single Cohort of Participants With Solid Tumors (Malignancies)

Solid Tumors

Hungary
University Hospital, Basel, Switzerland

Completed

Oral Glucosestimulation After Gastric Bypass Surgery

Obesity

Switzerland
Cytonet GmbH & Co. KG

Completed

Study to Evaluate 13 C Isotope Ratio Measurement for Urea Cycle Capacity Assessment

Urea Cycle Disorders

Germany
Genfit
SGS Life Sciences, a division of SGS Belgium NV

Completed

Mass Balance Study of 14C-labelled GFT505 in Healthy Volunteers

Healthy

Belgium
Diego Moretti
Swiss Federal Institute of Technology; Wageningen University and Research; St... and other collaborators

Completed

True Ileal Amino Acid Digestibility of Tenebrio Molitor Larvae in Women

Malnutrition; Protein

Switzerland
University of Alabama at Birmingham

Withdrawn

Neuroinflammation and Age-associated Brain Pathology: Two Potential Mechanisms of Cognitive Impairment in Ovarian Cancer

Ovarian Cancer

United States
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Completed

Enteric Oxalate Absorption Study in Unclassified Hyperoxaluria

Hyperoxaluria | Enteric Hyperoxaluria

United States
Pfizer

Completed

Single Dose Study With Unlabeled Dose and 14C-labeled Microdose of PF-06700841 in Healthy Male Subjects

Healthy Male Subjects

Netherlands
Robert Bok, MD, PhD
National Cancer Institute (NCI); National Institute for Biomedical Imaging... and other collaborators

Recruiting

Hyperpolarized 13C Pyruvate as a Biomarker in Advanced Solid Tumors

Advanced Solid Tumor

United States
University of Wisconsin, Madison

Recruiting

In Vivo Metabolic Profiling of CLL (Chronic Lymphocytic Leukemia)

Chronic Lymphocytic Leukemia

United States
National University Hospital, Singapore

Unknown

Evaluation of 11C-acetate PET Imaging as a Novel Approach to Detecting Pathology in Pulmonary TB

Tuberculosis, Pulmonary

Singapore
Cytonet GmbH & Co. KG
CRS Clinical Research Services Mannheim GmbH

Completed

Study in Healthy Subjects, Patients With Urea Cycle Disorders (UCD) and Carriers of UCD Mutations to Evaluate Urea Cycle Function

Urea Cycle Disorders

Germany
Merck KGaA, Darmstadt, Germany
Threshold Pharmaceuticals

Completed

A Phase 1 TH-302 Mass Balance Trial

Solid Tumor

Germany
University of Florida

Completed

13C-Pyruvate Breath Test (PBT)

Healthy

United States
Robert Flavell, MD, PhD
Bristol-Myers Squibb; U.S. Army Medical Research Acquisition Activity

Recruiting

Magnetic Resonance (MR) Imaging With Hyperpolarized Bicarbonate (13C) to Measure Tissue pH in Prostate Cancer

Prostate Cancer | Localized Prostate Carcinoma

United States
Chang Gung Memorial Hospital

Not yet recruiting

13C Pyruvate DNP MR Spectroscopy for Lymphoma Treatment Response Assessment

Patient Outcome Assessment
Chang Gung Memorial Hospital
Ministry of Science and Technology, Taiwan

Recruiting

Hyperpolarized 13C Pyruvate MRI for Early Immune Evaluation in Cervical Cancer Patients at Baseline and CCRT Therapy

Cervical Cancer

Taiwan
Pennington Biomedical Research Center

Completed

Evaluating Glial Acetate Metabolism as a Biomarker of Hypoglycemic Complications in Diabetic Patients (GLEAM)

Hypoglycemia | Diabetes

United States
Astellas Pharma Global Development, Inc.

Completed

A Study to Learn How [14C]ASP0367 is Processed by the Body in Healthy Men

Healthy Volunteers

United States
Justin Sims

Terminated

11C-acetate for Treatment Response After Radiotherapy for HCC

Hepatocellular Carcinoma

United States
Turku University Hospital

Completed

PET/MRI and Biomarkers in Bladder Cancer (ACEBIB)

Bladder Cancer

Finland
Karolinska Institutet

Completed

Hemodynamic Effects of Cold Versus Warm Fluid Bolus

Temperature Change, Body | Hypovolemia

Sweden
Université de Sherbrooke
McMaster University; University of Ottawa

Completed

Effects of Fructose/Glucose-rich Diet on Brown Fat in Healthy Subjects (GB7) (GB7)

Type2 Diabetes

Canada
University of Alabama at Birmingham

Withdrawn

Cardiac Perfusion and Metabolism With [11C] Acetate PET/CT is Associated With Hematopoietic System Activation in Acute Decompensated Heart Failure: An Imaging Sub-study

Acute Decompensated Heart Failure

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

C-Acetate PET/CT Imaging to Evaluate Treatment Changes in Prostate Cancer

Prostate Cancer Patients

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Study to Evaluate the Pharmacokinetics of 14C-labeled Isavuconazole Following a Single Oral Dose of 14C-labeled Prodrug Isavuconazonium Sulfate (BAL8557) in Healthy Male Subjects

Healthy Subjects | Pharmacokinetics of 14C-labeled Isavuconazole

United States
University of Michigan

Completed

An Exploratory Study of 18F-Labeled Hydroxyphenethylguanidines in Heart Failure Patients

Cardiomyopathy

United States
Loma Linda University

Terminated

Non-invasive Clinical Imaging of Cerebral Metabolism Following Brain Injury Using 13C Magnetic Resonance Spectroscopy.

Traumatic Brain Injury

Search clinical trials for: 13C-labeled Acetate

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