Search clinical trials for: 3, 4-Diaminopyridine

Total 10362 results

Jeffrey A. Cohen, MD
Jacobus Pharmaceutical

Terminated

Controlled Trial of 3,4-Diaminopyridine (3-4DAP) in Lambert-Eaton Myasthenic Syndrome (LEMS) (3-4DAP)

Muscle Weakness

United States
National Center for Research Resources (NCRR)
Mayo Clinic

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of 3,4-Diaminopyridine for Demyelinating Polyneuropathy

Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Acorda Therapeutics

Completed

Safety and Efficacy Study of Oral Fampridine-SR in Patients With Multiple Sclerosis

Multiple Sclerosis

United States, Canada
Coordinación de Investigación en Salud, Mexico

Completed

Efficacy and Safety of 4-aminopyridine on Cognitive Performance and Motor Function of Patients With Multiple Sclerosis

Multiple Sclerosis

Mexico
FDA Office of Orphan Products Development

Completed

Assessment of Chronic Guillain-Barre Syndrome Improvement With Use of 4-aminopyridine

Guillain-Barre Syndrome

United States
University of Rochester

Withdrawn

4-aminopyridine Treatment for Nerve Injury From Radical Retro-Pubic Prostatectomy

Prostate Disease

United States
Acorda Therapeutics

Completed

Open-Label Extension Study to Evaluate the Safety, Tolerability and Activity of Oral Fampridine-SR in Patients With Multiple Sclerosis Who Participated in the MS-F204 Trial

Multiple Sclerosis

United States, Canada
Acorda Therapeutics

Completed

Study of Oral Fampridine-SR in Multiple Sclerosis

Multiple Sclerosis

United States, Canada
Acorda Therapeutics

Completed

Study of Fampridine-SR Tablets in Multiple Sclerosis Patients

Multiple Sclerosis

United States, Canada
Acorda Therapeutics

Completed

Open-Label Extension Study to Evaluate the Safety, Tolerability and Activity of Oral Fampridine-SR Tablets in Multiple Sclerosis Patients Who Participated in the MS-F203 Trial

Multiple Sclerosis

United States, Canada
Acorda Therapeutics

Completed

Open-Label Extension Study to Evaluate the Safety, Tolerability and Activity of Oral Fampridine-SR in Patients With Multiple Sclerosis

Multiple Sclerosis

United States, Canada
Columbia University

Completed

Short and Long Term Treatment With 4-AP in Ambulatory SMA Patients

Spinal Muscular Atrophy

United States
Kessler Foundation
National Institute on Disability, Independent Living, and Rehabilitation... and other collaborators

Completed

Combination Therapy With Dalfampridine and Locomotor Training for Chronic, Motor Incomplete Spinal Cord Injury

Spinal Cord Injury

United States
University of Zurich

Unknown

Characterization of the Effects of Prolonged-release Fampridine on Ambulatory Function in Patients With Multiple Sclerosis (FAMPKIN)

Multiple Sclerosis

Switzerland
Pharma Holdings AS
CTC Clinical Trial Consultants AB

Completed

Study to Evaluate the Efficacy, Safety and Tolerability of 3% LTX-109 for Nasal Decolonisation of Staphylococcus Aureus

Nasal Decolonization of Staphylococcus Aureus

Sweden
University of Colorado, Denver

Approved for marketing

Use of 3,4-Diaminopyridine in the Treatment of Lambert-Eaton Syndrome (3 4-DAP)

Lambert Eaton Myasthenic Syndrome

United States
David P. Richman, MD
Jacobus Pharmaceutical

No longer available

Treatment of Lambert-Eaton Syndrome With 3,4 DAP

Lambert Eaton Myasthenic Syndrome

United States
Seoul National University Hospital

Unknown

Verify the Effectiveness rTMS Using MEG (rTMS)

Tinnitus

Korea, Republic of
Merz Pharmaceuticals GmbH

Completed

Post-Market Clinical Follow-up Performance and Safety Study of Etermis 3 and 4 in the Face (POMET)

Correction of Facial Wrinkles/Folds | Facial Volume Enhancement

Germany
John Elfar
University of Arizona

Active, not recruiting

4-aminopyridine Treatment for Nerve Injury

Prostate Cancer | Nerve Injury

United States
Wuhan University

Completed

Effects of Exercise Training at Different Timeline on Shoulder Dysfunction After Breast Cancer Modified Radical Mastectomy

Breast Cancer | Modified Radical Mastectomy | Shoulder Dysfunction

China
Coordinación de Investigación en Salud, Mexico

Active, not recruiting

High Doses of 4-aminopyridine in Clinically Complete Chronic Spinal Cord Injury Patients.

Spinal Cord Injuries | Chronic

Mexico
Otto Bock Healthcare Products GmbH

Completed

C-Leg 3 and C-Leg 4 Study in Transfemoral Amputees

Lower Limb Amputation Above Knee (Injury)

Austria, Belgium
Klinikum der Universität Köln

Unknown

Comparison of TOT 8/4 Versus TOT 6/3 (URGE-III)

Urinary Incontinence

Germany
Valenta Pharm JSC

Recruiting

Safety, Tolerability and Pharmacokinetics of 4-MUST, Tablets, 128 mg (Valenta Pharm JSC) During Single and Multiple Oral Administration in Healthy Volunteers

Cholecystitis

Russian Federation
John Elfar

Not yet recruiting

4AP to Delay Carpal Tunnel Release (CTR) (CTR)

Carpal Tunnel Syndrome | Compression Neuropathy
University of Bologna

Recruiting

Optimizing CO2 Injection Technique for EVAR

Abdominal Aortic Aneurysm | Endovascular Aortic Repair

Italy
Loyola University
National Cancer Institute (NCI)

Active, not recruiting

Transfer of Genetically Engineered Lymphocytes in Melanoma Patients

Melanoma

United States
XOMA (US) LLC

Completed

A Single-Dose Open-Label Study of XOMA 358 in Subjects With Congenital Hyperinsulinism

Congenital Hyperinsulinism

United Kingdom, United States
University of Colorado, Denver
Johnson & Johnson

Completed

A Pilot Study: Snacking, Willpower and Glucose Availability (SWG)

Willpower

United States
National Cancer Institute (NCI)

Recruiting

Testing the Response to the Anti-cancer Drug, Triapine, in Uterine Cancers Using Markers From the Tissue at the Time of Hysterectomy

Endometrial Serous Adenocarcinoma

United States
University of Southern Denmark
Odense University Hospital; Fonden til Lægevidenskabens Fremme; Sygehus Lillebaelt and other collaborators

Completed

Muscle Strain in Multiple Sclerosis Patients Measured by Ultrasound Speckle Tracking Technique (MUST)

Multiple Sclerosis

Denmark
Genesis Pharma CNS & Specialty

Completed

Fampridine in MS Patients: A Cognition, Fatigue, Depression and Quality of Life Analysis (FAMILY)

Multiple Sclerosis

Greece
Brigham and Women's Hospital

Completed

Effect of Dalfampridine (4-AP) on Genioglossus Muscle Activity in Healthy Adults (APIGLOSS)

Sleep Apnea, Obstructive

United States
University of California, Los Angeles
University of South Florida; University of Rochester

Withdrawn

4-Aminopyridine in Episodic Ataxia Type 2 (4AP in EA2)

Episodic Ataxia Type 2

United States
Hospital Departamental de Villavicencio
Cooperative University of Colombia

Recruiting

Severe Dengue in Critical Care at Villavicencio, Colombia.

Severe Dengue

Colombia
The University of Tennessee, Knoxville

Recruiting

Foods Within a Meal and Food Liking Study

Obesity | Diet Habit

United States
Istanbul University - Cerrahpasa (IUC)

Active, not recruiting

Comparison of Mental Skills of Professional Esports Players With Different Levels of Physical Activity

Healthy | Physical Inactivity

Turkey
Mount Saint Vincent University

Completed

The Effect of Pulse Flours on Blood Glucose, Satiety and Food Intake

Blood Glucose | Eating | Food | Appetite

Canada
Société des Produits Nestlé (SPN)

Completed

Effect of Changes in Glucose Intake and Sweet Perception on Post Prandial Glycaemia

Healthy

Switzerland
University of California, San Francisco
National Institute on Aging (NIA); Alzheimer's Association; Posit Science Corporation and other collaborators

Completed

The Mental Activity and eXercise Trial for Seniors (MAX)

Cognitive Impairment

United States
University of Arizona
National Institute of Neurological Disorders and Stroke (NINDS)

Not yet recruiting

4-AP Peripheral Nerve Crossover Trial

Peripheral Nerve Injury | Crush Injury
Hospital for Special Surgery, New York

Active, not recruiting

Use of Dalfampridine in Primary Lateral Sclerosis

Motor Neuron Disease, Upper

United States
Fox Chase Cancer Center
University of South Carolina; Temple University; Thomas Jefferson University; Rutgers...

Not yet recruiting

Reducing Urban Cervical Cancer Disparities

Cervical Cancer | Papilloma Viral Infection

United States
University of Florida

Completed

Effects of Acute Intermittent Hypoxia on Sensory Function in Healthy Adults (SensoryFLO)

Sensitivity

United States
Duke University
National Institute of Nursing Research (NINR)

Completed

Preventing Pressure Ulcers With Repositioning Frequency and Precipitating Factors

Pressure Ulcer

United States
Lawson Health Research Institute

Withdrawn

GlideScope Groove Versus Macintosh Blade for Double-Lumen Endotracheal Tube Intubation

Intubation, Intratracheal

Canada
John Elfar

Not yet recruiting

4-aminopyridine for Skin Wound Healing

Wounds and Injuries | Wound Heal | Wounds | Wound of Skin

United States
Prof. Dominique de Quervain, MD
University Hospital, Basel, Switzerland; Clinical Trial Unit, University Hospital...

Withdrawn

Influence of Fampridine on Working Memory in Healthy Subjects (Fampyr_2020)

Working Memory

Switzerland
State University of New York at Buffalo

Completed

Effects of Dalfampridine on Cognition in Multiple Sclerosis

Multiple Sclerosis

United States

Search clinical trials for: 3, 4-Diaminopyridine

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