Search clinical trials for: 600mg DKN-01

Total 2231 results

Massachusetts General Hospital
Bristol-Myers Squibb; Leap Therapeutics, Inc.

Terminated

Study of the Combination of DKN-01 and Nivolumab in Previously Treated Patients With Advanced Biliary Tract Cancer (BTC)

Biliary Tract Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Merck Sharp & Dohme LLC; Leap Therapeutics,...

Recruiting

Phase 2 Study Evaluating the Efficacy of the Combination of DKN-01 (DKK1 Inhibitor, Leap Therapeutics) and Pembrolizumab in the Treatment of Advanced or Recurrent Endometrial Cancer

Endometrial Cancer

United States
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Active, not recruiting

A Dose Ranging Placebo-controlled Double-blind Study to Evaluate the Safety, Pharmacokinetics and Efficacy of 610 in Participants With Severe Eosinophilic Asthma

Asthma

China
Corcept Therapeutics

Completed

First-in-human Study in Healthy Subjects

Healthy

United Kingdom
Suzhou Zelgen Biopharmaceuticals Co.,Ltd
Tigermed Consulting Co., Ltd

Completed

Safety and Efficacy of Donafenib in Patients With Advanced Hepatocellular Carcinoma

HCC

China
Aclaris Therapeutics, Inc.

Completed

ATI-501 Oral Suspension Compared to Placebo in Subjects With Alopecia Areata, Alopecia Universalis or Alopecia Totalis

Alopecia

United States
Chelsea and Westminster NHS Foundation Trust
Merck Sharp & Dohme LLC

Recruiting

The Effect on Lipid Profile of Switching to Delstrigo in HIV Positive Patients (META-D)

Hiv

United Kingdom
Idorsia Pharmaceuticals Ltd.

Completed

Single-ascending Dose Study to Investigate the Tolerability, Safety, Pharmacokinetics, and Pharmacodynamics of ACT-462206

Pharmacokinetics | Pharmacodynamics | Tolerability | Safety

Netherlands
Chengdu Easton Biopharmaceuticals Co,Ltd

Recruiting

A Randomized, Double-blind, Placebo-controlled, Multicenter Clinical Trial to Evaluate the Clinical Efficacy and Safety of Yogliptin Tablets

Type 2 Diabetes

China
Bio-Thera Solutions

Completed

A Phase I Clinical Trial of BAT4306F on Safety, Tolerability and Pharmacokinetics for Patients

Non-Hodgkin's Lymphoma

China
Japan Tobacco Inc.

Completed

Efficacy and Safety of JTT-705 300, 600 And 900mg in Comparison With Placebo in Patients With Type II Hyperlipidaemia

Type II Hyperlipidaemia

Netherlands
SOM Innovation Biotech SA

Completed

Efficacy and Safety of SOM3355 in Huntington's Disease Chorea

Huntington's Chorea

Spain
Dong Wha Pharmaceutical Co. Ltd.

Completed

To Determine the Efficacy and Safety of DW1029M on Microalbuminuria in Patients With Diabetic Nephropathy

Diabetic Nephropathy

Korea, Republic of
RDC Clinical Pty Ltd

Recruiting

Effect of Testofen on Erectile Function in an Adult Male Population

Erectile Dysfunction

Australia
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Not yet recruiting

A Phase II Study of 610 in Participants With Severe Eosinophilic Asthma

Asthma

China
Sensorion

Completed

Efficacy of SENS-111 in Patients Suffering From Acute Unilateral Vestibulopathy

Acute Unilateral Vestibulopathy (AUV)

United States, Israel, France, Korea, Republic of, Hungary, Germany, Czechia, Italy
Hyundai Pharmaceutical Co., LTD.

Completed

Change From Baseline to Chronic Kidney Disease Patient Before and After Administration Drug

Chronic Renal Failure
PharmatrophiX Inc.
National Institute on Aging (NIA)

Completed

Study of LM11A-31-BHS in Mild-moderate AD Patients

Mild to Moderate Alzheimer's Disease

Spain, Germany, Austria, Czechia, Sweden
Xijing Hospital of Digestive Diseases

Completed

Primary Chemoprevention of Familial Adenomatous Polyposis With Berberine Hydrochloride

Colorectal Adenomas

China
Leap Therapeutics, Inc.

Completed

A Study of DKN-01 and Lenalidomide/Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma

United States
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Unknown

A Clinical Study of SKLB1028 Capsule in the Treatment of Recurrence/Refractory AML Patients

Acute Myeloid Leukemia

China
European Organisation for Research and Treatment...
Hoffmann-La Roche; Leap Therapeutics, Inc.

Withdrawn

Combination of Targeted and Immunotherapy for Advanced Biliary Tract and Esophagogastric Gastric Cancer (DYNAMIC)

Esophageal Cancer | Hepatobiliary Neoplasm | Biliary Tract Cancer | GastroEsophageal Cancer
khalid abd aziz mohamed

Completed

Calcium Dobesilate Versus Coasting for Prevention of Ovarian Hyperstimulation Syndrome

Infertility

Egypt
Dow University of Health Sciences

Completed

Prevention of Dry Socket by Means of Single Preoperative Antibiotics Compared to Conventional Therapy

Dry Socket

Pakistan
Shandong Luoxin Pharmaceutical Group Stock Co.,...

Completed

A Phase I Study of LuoXin Innovate (LXI-15028) in Healthy Chinese Subjects to Evaluate the Pharmacokinetics, Safety and Tolerability.

Healthy

China
Bastyr University
Michael J. Fox Foundation for Parkinson's Research

Completed

Phase IIb Study of Intranasal Glutathione in Parkinson's Disease ((in)GSH)

Parkinson's Disease

United States
Yuhan Corporation

Completed

A Study to Evaluate the Effect of Sarpogrelate on Blood Hyperviscosity

Peripheral Artery Disease, PAD

Korea, Republic of
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Unknown

A Study of Benzonatate Soft Capsule in Chinese Healthy Subjects

Cough

China
Maxinovel Pty., Ltd.

Not yet recruiting

A Study of MAX-40279combined With KN046 in Patients With Advanced / Metastatic Solid Tumors

Advanced / Metastatic Solid Tumors
Hyundai Pharmaceutical Co., LTD.

Completed

Compare Safety and Pharmacokinetic Properties of Surfolase Capsule(Acebrophylline 100mg) and Surfolase CR(200mg)

Healthy Male
Chia Tai Tianqing Pharmaceutical Group Nanjing...

Recruiting

A Clinical Study of TQH2722 Injection in the Treatment of Chronic Sinusitis With or Without Nasal Polyps.

Sinusitis

China
Supernus Pharmaceuticals, Inc.

Completed

Evaluation of SPN-812 (Viloxazine Extended-release Capsule) High Dose in Adolescents With ADHD

ADHD

United States
HK inno.N Corporation

Completed

Drug-Drug Interaction Study Between CJ-12420 and Clarithromycin in Healthy Male Subjects

Healthy

Korea, Republic of
Cheng-Chung Wei
Golden Biotechnology Corporation

Unknown

A Randomized, Placebo-controlled Trial of Antroquinonol in Patients With Chronic Hepatitis B

Chronic Hepatitis B

Taiwan
OrthoTrophix, Inc

Completed

A Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 in Subjects With Mild to Moderate Patello-Femoral Osteoarthritis Involving Both Knees

Knee Osteoarthritis

United States
Yu-Jay Corp.

Completed

Therapeutic Drug Monitoring Study of Reduced-Dose Efavirenz (400 mg) in Combo Tablet for Patients Receiving Atripla With Viral Suppression in Taiwan

HIV Infections

Taiwan
Kirby Institute

Completed

A Randomised, Open-label Trial to Assess the Safety and Efficacy of Switching to Tenofovir-emtricitabine or Abacavir-lamivudine: The STEAL Study

HIV Infections

Australia
Western University, Canada

Unknown

Effect of Branched-chain Amino Acid Supplementation on Muscle Damage

Muscle Damage

Canada
Chong Kun Dang Pharmaceutical

Completed

The Clinical Trial to Evaluate the Efficacy and Safety of CKD-497

Respiratory Infection

Korea, Republic of
ViiV Healthcare
GlaxoSmithKline

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Repeat Dose Administration of Long-Acting GSK1265744 and Long-Acting TMC278 Intramuscular and Subcutaneous Injections in Healthy Adult Subjects

Infection, Human Immunodeficiency Virus

United States
Vigonvita Life Sciences

Completed

A Study to Evaluate the Bioavailability, Food Effect and Pharmacokinetics of Deuremidevir Hydrobromide for Suspension

Healthy Subjects

China
Otsuka Pharmaceutical Co., Ltd.
UCB Japan Co. Ltd.

Completed

Efficacy Confirmation Trial of CDP870 as add-on Medication to Methotrexate (MTX) in Japanese Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

Japan
Chengdu Zenitar Biomedical Technology Co., Ltd

Recruiting

A Randomized, Double-blind,Dose-escalating, Single-dose, Oral Phase I Clinical Study of Flunotinib Healthy People

Healthy Person

China
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Completed

Evaluation of 611 in Chinese Adult Patients With Moderate-to-Severe Atopic Dermatitis

Dermatitis, Atopic

China
Galmed Research and Development, Ltd.

Enrolling by invitation

Open-Label Study to Evaluate the Safety, Tolerability, and PK of Aramchol in Subjects With Hepatic Impairment

Hepatic Impairment

United States
Shanghai Greenvalley Pharmaceutical Co., Ltd.
Shanghai Mental Health Center

Completed

Safety, Efficacy and Dose Titration of Sodium Oligo-mannurarate Capsule on Mild to Moderate Alzheimer's Disease

Cognitive Impairment | Alzheimer Disease

China
IlDong Pharmaceutical Co Ltd

Unknown

Study to Evaluate Pharmacokinetics, Safety, and Tolerability Ildong COL-144 Tablet in Korean Healthy Volunteers

Healthy
University of Kansas Medical Center
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Prenatal DHA and Neurofunctional Development (PANDA)

Use and Dose of Prenatal DHA Supplementation

United States
GlaxoSmithKline

Completed

Evaluate Safety, Tolerability, and Pharmacokinetics of Single and Repeat IV Doses

Infections, Respiratory Tract

Australia
GlaxoSmithKline

Completed

Crossover Study to Evaluate the Pharmacokinetics of Ezogabine/Retigabine in Taiwanese Subjects

Epilepsy

Taiwan

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