Search clinical trials for: ALM-488

Total 255121 results

Beijing InnoCare Pharma Tech Co., Ltd.

Recruiting

Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of ICP-488 in Patients With Moderate to Severe Plaque Psoriasis

Moderate to Severe Plaque Psoriasis

China
Beijing InnoCare Pharma Tech Co., Ltd.

Recruiting

A Clinical Study of ICP-488 in Healthy Subjects and Patients With Psoriasis

Psoriasis

China
Alume Biosciences, Inc.

Completed

A Study of ALM-488 to Highlight Nerves in Patients Undergoing Head & Neck Surgery

Head and Neck Neoplasms | Surgery | Thyroid Neoplasms | Nerve Injury | Parotid Neoplasm | Imaging

United States
Alume Biosciences, Inc.
Ergomed

Recruiting

Feasibility Study- REVEAL 475 for Bevonescein-Assisted Nerve Visualization in Head & Neck Surgery

Head and Neck Surgery

United States
University of Edinburgh
Umeå University

Completed

The Effects of Diesel Exhaust Inhalation on Vascular Function - the Role of Endothelin

Coronary Disease

Sweden
Takeda

Completed

TAK-438 - Safety, Blood Levels & Effects of Repeated Doses (TAK-438_107)

Gastroesophageal Reflux Disease (GERD) | Erosive Esophagitis(EE)

United Kingdom
Millennium Pharmaceuticals, Inc.

Terminated

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Single and Multiple Oral Dose of TAK-418 in Healthy Female Participants

Healthy Volunteers

United States
NeurAxon Inc.

Completed

Study of the Safety and Effectiveness of NXN-188 for the Treatment of Migraine Headache Without Aura

Migraine Without Aura

United States
Chong Kun Dang Pharmaceutical

Recruiting

A Phase 2 Study to Evaluate the Safety and Efficacy of CKD-498 in Female Patients With Androgenetic Alopecia

Androgenetic Alopecia

Korea, Republic of
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

CBM588 in Improving Clinical Outcomes in Patients Who Have Undergone Donor Hematopoietic Stem Cell Transplant

Hematopoietic and Lymphoid Cell Neoplasm

United States
Takeda

Withdrawn

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of TAK-988 in Healthy Participants

Healthy Volunteers

United States
Takeda

Completed

A Bioequivalence (BE) Study of TAK-438 Orally Disintegrating (OD) Tablet

Japanese Healthy Adult Male

Japan
Takeda

Completed

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Ascending Oral Single Dose of TAK-418 in Healthy Participants

Healthy Participants

United States
Takeda

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TAK-438 in Healthy Male Participants

Dose Finding Study
Takeda

Terminated

Effects of TAK-448 in Middle-aged and Older Men With Low Testosterone

Low Testosterone

United States
Jazz Pharmaceuticals
Children's Oncology Group (COG)

Completed

An Open-Label Study of JZP-458 (RC-P) in Patients With Acute Lymphoblastic Leukemia (ALL)/Lymphoblastic Lymphoma (LBL)

Acute Lymphoblastic Leukemia | Lymphoblastic Leukemia

United States, Canada
AbbVie (prior sponsor, Abbott)

Completed

Efficacy and Safety Study for Cognitive Deficits in Adult Subjects With Schizophrenia

Cognitive Deficits in Schizophrenia

United States
Alume Biosciences, Inc.
Ergomed

Recruiting

ALM-488 for Intra-Operative Visualization of Nerves in Head and Neck Surgery

Surgery

United States
ML Bio Solutions, Inc.

Active, not recruiting

Study of BBP-418 in Patients With LGMD2I

LGMD2I

United States
ES Therapeutics Australia Pty Ltd

Withdrawn

ES-481 for Uncontrolled Glioma-Associated Epilepsy and Assessment for Potential Anti-Tumorigenic Effect in Patients With Isocitrate Dehydrogenase 1 (IDH1) Mutant Tumors

Epilepsy; Seizure
CytomX Therapeutics

Withdrawn

PROCLAIM-CX-188: A Trial to Find Safe and Active Doses of an Investigational Drug CX-188 for Patients With Solid Tumors

Solid Tumor, Adult

United States
Takeda

Completed

A Pharmacokinetic Study of TAK-438 in Healthy Adult Chinese Participants

Healthy Participants

China
Mast Therapeutics, Inc.
CytRx

Completed

Phase III Randomized Study of Poloxamer 188 for Vaso-Occlusive Crisis of Sickle Cell Disease

Sickle Cell Anemia
Diakron Pharmaceuticals

Completed

A Healthy Volunteer Study to Evaluate for a Single Dose of 4 Different Tablets of DPOC-4088 the Absorption and Elimination From the Body and the Potential Effect on Blood Clotting

Deep Vein Thrombosis Leg

Belgium
Valbiotis
University Hospital, Clermont-Ferrand; Clinic'n'Cell

Recruiting

Determination of Biological Activity of Enriched Serum Following TOTUM-448 Consumption (CnC-TOTUM448)

NAFLD | MASLD | Mild Inflammatory Context

France
Recursion Pharmaceuticals Inc.

Recruiting

A Study of REC-4881 in Participants With Cancers Which Have an AXIN1 or APC Mutation

Solid Tumor | APC Gene Mutation | AXIN1 Gene Mutation

United States
Huashan Hospital

Recruiting

Alterations of Gut Microbiome, Function, and Its Intervention After Defunctioning Ileostomy

Rectal Cancer | Ileostomy - Stoma | Microbial Disease | Intestinal Functional Disorder

China
Takeda

Completed

Long-Term Safety Study of TAK-438 in the Maintenance Treatment of Healed Erosive Esophagitis

Erosive Esophagitis

Japan
Celgene

Completed

Safety Study of Oral Azacitidine (CC-486) as Maintenance Therapy After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in Participants With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndromes (MDS).

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute

United States, United Kingdom
Cullinan Oncology Inc.
Harbour BioMed US, Inc.

Recruiting

CLN-418 Study on Subjects With Advanced Solid Tumors

Advanced Solid Tumor

Australia, United States
Carmot Therapeutics, Inc.
Carmot Australia First Pty Ltd

Recruiting

A Study of CT-388 in Otherwise Healthy Overweight and Obese Adults and Patients With Type 2 Diabetes Mellitus

Diabetes

Australia, Mexico
Reata, a wholly owned subsidiary of Biogen

No longer available

Expanded Access to Omaveloxolone for Melanoma for Patients Previously Enrolled in 408-C-1401

Melanoma
Proteostasis Therapeutics, Inc.

Completed

Study Assessing PTI-428 Safety, Tolerability, and Pharmacokinetics in Subjects With Cystic Fibrosis

Cystic Fibrosis

United States, Canada, France, Denmark, Germany
AbbVie

Completed

A Multiple Dose Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ABT-288 in Stable Subjects With Schizophrenia

Schizophrenia
Takeda

Completed

Safety, Tolerability and Pharmacokinetics of TAK-438 in Healthy Male Participants

Ascending Single Dose Study
Takeda

Completed

Efficacy of TAK-438 Compared to Placebo in the Treatment of Non-Erosive Gastroesophageal Reflux Disease

Non-erosive Gastroesophageal Reflux Disease

Japan
Comanche Biopharma

Recruiting

Study of CBP-4888 in Healthy, Non-Pregnant Female Subjects

Healthy Volunteer Study

United States
Reata, a wholly owned subsidiary of Biogen

Completed

A Pharmacokinetic Study of Omaveloxolone in Healthy Volunteers

Healthy

United States
iTeos Belgium SA

Completed

First-In-Human Study of EOS884448 in Participants With Advanced Cancers.

Advanced Cancer

Belgium
Diakron Pharmaceuticals
Drug Research Unit Ghent, Ghent, Belgium; Kinesis Pharma B.V.

Terminated

A Healthy Volunteer Study to Investigate the Blood Concentrations, the Effect on Blood Clotting and the Safety of Multiple Doses of DPOC-4088 Tablets in Different Doses.

Deep Vein Thrombosis Leg | Stroke (in Patients With Atrial Fibrillation)

Belgium
Enanta Pharmaceuticals, Inc

Completed

Evaluation of the Safety and Pharmacokinetics of a Single Oral Dose of EDP-788

Safety in Normal Volunteers

United States
University Hospital, Rouen

Completed

Assessment of Probe Based Confocal Laser Endo-microscopy for In-vivo Diagnosis of Peripheral Lung Nodules and Masses. (NODIVEM)

Pulmonary Nodule Persistent | Malignant Neoplasm of the Respiratory System | Benign Neoplasms of the Respiratory System

France
Volastra Therapeutics, Inc.

Recruiting

A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

Gastric Adenocarcinoma | Uterine Carcinosarcoma | Triple Negative Breast Cancer | Advanced Solid Tumor | Head and Neck Squamous Cell Carcinoma | Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Transitional Cell Carcinoma of Bladder | Colorectal Adenocarcinoma | Gastroesophageal Junction... and other conditions

United States
China Medical University Hospital

Completed

The Effect of Probiotics on Depression Syndrome and Risk Factors of Cardiovascular Disease in Hemodialysis Patients

Cardiovascular Diseases | Depression Mild

Taiwan
Cascadian Therapeutics Inc.

Completed

Phase I Trial of PX-478

Lymphoma | Advanced Solid Tumors

United States
Takeda

Completed

A Randomized, Double-Blind, Multicenter Study to Evaluate the Acid-inhibitory and Dose-response Efficacy of TAK-438 (20 mg, 40 mg) in Patients With Proton Pump Inhibitor (PPI) - Resistant Erosive Esophagitis

Erosive Esophagitis

Japan
University of Colorado, Denver
Bristol-Myers Squibb

Recruiting

CC-486 and Venetoclax for Acute Myeloid Leukemia

AML

United States
Biogen

Not yet recruiting

A Study of Omaveloxolone in Children With Friedreich's Ataxia

Friedreich Ataxia

United States
Reata, a wholly owned subsidiary of Biogen
AbbVie

Completed

RTA 408 in the Treatment of Advanced Solid Tumors (NSCLC & Melanoma) - DISCOVER (DISCOVER)

Metastatic or Incurable Non-small Cell Lung Cancer | Relapsed, Refractory Melanoma

United States
Takeda

Completed

A Study to Evaluate the Effect of High-Fat Meal on TAK-788 Pharmacokinetics (PK) in Healthy Adult Participants

Healthy Volunteers

United States

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