Search clinical trials for: ALX-0061

Total 255427 results

Ablynx

Completed

ALX-0061 Phase I Bioavailability Study in Healthy Volunteers

Rheumatoid Arthritis

Netherlands
Ablynx

Completed

Study to Assess Safety and Efficacy of Anti-Interleukin 6-receptor (IL6R) Nanobody in Rheumatoid Arthritis (RA) Patients

Rheumatoid Arthritis

Poland, Hungary, Czechia
Ablynx

Completed

An Open-Label Extension Study Assessing the Long-Term Efficacy and Safety of ALX-0061 in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Spain, Belgium, Bulgaria, Georgia, Germany, Hungary, Mexico, Moldova, Republic of, North Macedonia, Poland, Romania, Serbia
Ablynx, a Sanofi company

Completed

Phase III Trial With Caplacizumab in Patients With Acquired Thrombotic Thrombocytopenic Purpura (HERCULES)

Acquired Thrombotic Thrombocytopenic Purpura

United States, Australia, Austria, Belgium, Canada, Czechia, France, Germany, Hungary, Israel, Italy, Netherlands, Spain, Switzerland, Turkey, United Kingdom
Ablynx

Completed

A Phase II Study to Evaluate Safety and Efficacy of ALX-0061 in Subjects With Systemic Lupus Erythematosus

Lupus Erythematosus, Systemic

United States, Hungary, Spain, Philippines, Poland, Serbia, Argentina, Chile, Czechia, Germany, Korea, Republic of, Mexico, Peru, Portugal, Russian Federation, Taiwan, Ukraine
Novo Nordisk A/S

Recruiting

A Study to See How Safe a New Medicine (NNC6022-0001) is in Healthy People

Healthy Volunteers | Cardiometabolic Diseases

Netherlands
Novo Nordisk A/S

Active, not recruiting

A Research Study to Look at How a New Medicine Called NNC6019-0001 Works and How Safe it is for People Who Have Heart Disease Due to Transthyretin (TTR) Amyloidosis

Transthyretin Amyloid Cardiomyopathy (ATTR CM)

United States, Netherlands, Spain, Portugal, Canada, Czechia, France, Germany, Italy, Japan
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety of ITX 5061 in Treatment-Naive Hepatitis C (HCV)-Infected Adults

Hepatitis C

United States, Puerto Rico
Vaxon Biotech

Completed

Safety Study of Vx006 Vaccine in Solid Tumor Patients

Solid Tumor

Greece
Ablynx

Completed

A Phase IIb Study for ALX-0061 Monotherapy in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Czechia, Bulgaria, Germany, Mexico, Poland, Romania, Serbia, Spain, Hungary, United States, Belgium, Georgia, Moldova, Republic of, North Macedonia
Boehringer Ingelheim

Completed

Antiviral Efficacy, Pharmacokinetics and Safety of BILN 2061 ZW in Patients With Chronic Hepatitis C Virus Infection

Hepatitis C, Chronic
Genentech, Inc.

Completed

Ipatasertib (GDC-0068) Study to Evaluate Formulation Change and Food Effect on Bioavailability in Healthy Subjects

Cancer

United States
Toll Biotech Co. Ltd. (Beijing)

Recruiting

A Study of Single and Multiple Oral Doses of TollB-001

Rheumatoid Arthritis

China
Kukje Pharma

Completed

[KSR-001-P01]Clinical Trial to Evaluate the Safety, Tolerability and Pharmacokinetic Characteristic of KSR-001

Dry Eye Syndromes

Korea, Republic of
Patagonia Pharmaceuticals, LLC

Completed

A Safety and Tolerability Study of Topical PAT-001 in Congenital Ichthyosis

Congenital Ichthyosis

United States
Novo Nordisk A/S

Recruiting

A Research Study to Look at Long-term Treatment With a Medicine Called NNC6019-0001 for People Who Have Heart Failure Due to Transthyretin Amyloidosis

Transthyretin Amyloid Cardiomyopathy (ATTR CM)

United States, Netherlands, Germany, Canada, Czechia, France, Italy, Portugal, Spain
Eden Miller
Pendulum Therapeutics

Unknown

Effects on Glycemic Control of WBF-0031 in Subjects With Abnormal Glucose Tolerance

Abnormal Glucose Tolerance

United States
23andMe, Inc.

Active, not recruiting

A Phase 1/2a Study of 23ME-00610 in Patients With Advanced Solid Malignancies

Clear Cell Renal Cell Carcinoma | Fallopian Tube Cancer | Solid Tumor | Neuroendocrine Tumors | Epithelial Ovarian Cancer | Primary Peritoneal Carcinoma | Extensive-stage Small-cell Lung Cancer | MSI-H Cancer | Cancer With A High Tumor Mutational Burden

United States, Canada
Genentech, Inc.

Completed

A Study Evaluating the Safety and Tolerability of GDC-0068 in Patients With Refractory Solid Tumors

Solid Cancers

Spain
ReAlta Life Sciences, Inc.

Withdrawn

A Study of RLS-0071 in Patients With Acute Lung Injury Due to COVID-19 Pneumonia in Early Respiratory Failure

COVID-19 | Acute Lung Injury | ALI

United States
IntegoGen, LLC

Withdrawn

Allogeneic Micronized Amniotic Membrane Product for the Treatment of Hidradenitis Suppurativa

Hidradenitis Suppurativa

United States
Hoth Therapeutics, Inc.
Worldwide Clinical Trials

Recruiting

Study to Investigate the Efficacy, Safety, and Tolerability of Topical HT-001 for the Treatment of Skin Toxicities Associated With Epidermal Growth Factor Receptor Inhibitors (CLEER)

Acneiform Eruption Due to Chemical | Xerosis Cutis | Paronychia

United States
ReAlta Life Sciences, Inc.

Not yet recruiting

Safety, PK, PD, Dosing, and Efficacy of RLS-0071for the Treatment of Hospitalized Patients With Steroid-Refractory Acute Graft-versus-Host Disease (AURORA)

Steroid Refractory GVHD
Viramal Limited

Completed

Exploratory Study on Two Different Doses of VML-0001 on the Effects on Vaginal pH in Healthy Post-Menopausal Women

Vaginal Atrophy

United States
Pharmaceutical Project Solutions, Inc.
Cognitive Research Corporation

Completed

PK Study of Intranasal RX0041-002 in Subjects With Severe Renal Impairment and Normal Renal Function

Healthy

United States
Kukje Pharma
Samil Pharmaceutical Co., Ltd.

Completed

[KSR-001-P02] Phase 2b/3 Study, Evaluate the Efficacy and Safety of KSR-001 in Patients With Dry Eye Syndrome

Dry Eye Syndromes

Korea, Republic of
BiondVax Pharmaceuticals ltd.

Completed

A Pivotal Trial to Assess the Safety and Clinical Efficacy of the M-001 as a Standalone Universal Flu Vaccine

Influenza

Poland
Ablynx, a Sanofi company

Completed

Study to Assess Efficacy and Safety of Anti-von Willebrand Factor (vWF) Nanobody in Patients With Acquired Thrombotic Thrombocytopenic Purpura (aTTP) (TITAN)

Acquired Thrombotic Thrombocytopenic Purpura

United States, Austria, Belgium, France, Germany, Israel, Italy, Spain, Switzerland, United Kingdom, Bulgaria, Romania, Australia
ReAlta Life Sciences, Inc.

Recruiting

Safety, PK and PD Relationships of RLS-0071 in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Acute Exacerbation of Chronic Obstructive Pulmonary Disease

United States
Novo Nordisk A/S

Recruiting

A Study to Look at Safety and Tolerability of NNC0582-0001, How it is Transported Throughout the Body and How it Works in Healthy Adults

Healthy Volunteers

Austria
Genentech, Inc.

Completed

A Study of Ipatasertib in Participants With Mild, Moderate or Severe Hepatic Impairment Compared to Healthy Participants

Hepatic Insufficiency

United States
BiondVax Pharmaceuticals ltd.

Completed

A Double-Dose Safety Study of An Influenza Vaccine (Multimeric-001)

Healthy

Israel
JANSSEN Alzheimer Immunotherapy Research & Development...

Terminated

AAB-001 (Bapineuzumab) Open-Label, Long-Term Extension Study in Patients With Mild to Moderate Alzheimer's Disease

Alzheimer's Disease

United States
MediciNova

Recruiting

MN-001 in Non-alcoholic Fatty Liver Disease, Type 2 Diabetes Mellitus, and Hypertriglyceridemia

Diabetes Mellitus, Type 2 | Hypertriglyceridemia | Non-Alcoholic Fatty Liver Disease

United States
Ocellaris Pharma, Inc.

Recruiting

A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers

Sarcoma | Neoplasms | Renal Cell Carcinoma | Cervical Cancer | Cancer | Hepatocellular Carcinoma | Gastric Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Metastatic Cancer | Squamous Cell Carcinoma of Head and Neck | Bladder Cancer | Triple Negative Breast Cancer | Urothelial Carcinoma | Merkel Cell Carcinoma | Squamous... and other conditions

Canada
BiondVax Pharmaceuticals ltd.

Completed

Phase II Study to Assess Safety & Immunogenicity of Multimeric-001 Influenza Vaccine, Followed by TIV (BVX006)

Influenza

Israel
Frontera Therapeutics

Recruiting

Gene Therapy in Subjects With Biallelic RPE65 Mutation-associated Retinal Dystrophy

Biallelic RPE65 Mutation-associated Retinal Dystrophy

China
Heartseed Inc.

Recruiting

A Study of iPS Cell-derived Cardiomyocyte Spheroids (HS-001) in Patients With Heart Failure (LAPiS Study) (LAPiS)

Heart Failure | Ischemic Heart Disease

Japan
Rznomics, Inc.

Recruiting

A Study to Evaluate the Safety, Tolerability and Efficacy of RZ-001 With Valganciclovir (VGCV) in Subjects With Hepatocellular Carcinoma

Hepatocellular Carcinoma

Korea, Republic of
Longbio Pharma

Active, not recruiting

A Study of Single and Multiple Dose Administration of LP-001 in Healthy Subjects

Myelodysplastic Syndrome (MDS)

China
Astrogen, Inc.

Recruiting

Phase III Clinical Trial to Evaluate the Efficacy and Safey of AST-001 in ASD Children

Autism Spectrum Disorder

Korea, Republic of
StimuSIL
Ankara City Hospital Bilkent; Istanbul University - Cerrahpasa (IUC)

Recruiting

Assessing the Safety and Efficacy of a Novel Microneedling and Laser Device for Male Pattern Hair Loss (CS-SAGA-001)

Androgenetic Alopecia | Hair Loss | Male Pattern Baldness | Hair Loss/Baldness | Pattern Baldness

Turkey
MediciNova

Completed

Phase II Study Efficacy and Safety of Two Dosing Regimens of MN-001 in Patients With Interstitial Cystitis

Interstitial Cystitis

United States
Digestome Therapeutics

Completed

A First in Human Study to Assess the Safety, Tolerability, and Pharmacokinetics of DGX-001

Depressive Disorder

Australia
Traws Pharma, Inc.

Recruiting

Evaluation Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of 83-0060 in Healthy Volunteers

Healthy Volunteers Only

Australia
ReAlta Life Sciences, Inc.
Premier Research Group plc

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of RLS-0071 in Newborns With Moderate or Severe Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic Hypothermia (STAR)

Hypoxic-Ischemic Encephalopathy

United States
Pfizer
Kyowa Kirin Co., Ltd.

Terminated

A Study of PF-05082566 In Combination With Mogamulizumab In Patients With Advanced Solid Tumors

Advanced/Metastatic Solid Tumors

United States
University College, London

Completed

Non-invasive Brain Stimulation and Cognitive Processing in Depression

Unipolar Major Depressive Disorder

United Kingdom
Azura Ophthalmics
Syneos Health; Cliantha Research

Completed

A Multicenter Study Evaluating AZR-MD-001 in Patients With Meibomian Gland Dysfunction and Evaporative Dry Eye Disease (DED)

Dry Eye | Meibomian Gland Dysfunction

Canada, Australia, New Zealand
Aevi Genomic Medicine, LLC, a Cerecor company

Completed

PART B: Efficacy and Safety of AEVI-001 in Children and Adolescents With ADHD and Without mGluR Mutations

Attention Deficit Hyperactivity Disorder

United States

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