Search clinical trials for: ALX-0061

Total 257235 results

University of Dundee
Tenovus Scotland

Completed

Beta Blocker Therapy in Moderate to Severe COPD (ANDA2)

Chronic Obstructive Pulmonary Disease

United Kingdom
John Hays
Sanofi

Unknown

Aflibercept and FOLFOX6 Treatment for Previously Untreated Stage IV Colorectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IV Colon Cancer | Stage IV Rectal Cancer

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Breast Cancer Research Foundation

Completed

Trial of Partial Breast Irradiation With Various Concurrent Chemotherapy Regimens (PBIC)

Breast Cancer

United States
National Cancer Institute (NCI)

Terminated

Donor Stem Cell Transplant With No or Low-Intensity Chemotherapy Using Sirolimus and Treated Immune Cells to Treat Blood and Lymph Cancers

Lymphoma | Leukemia | Myeloproliferative Disorders | Myelodysplastic Syndrome | Multiple Myleoma

United States
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Efavirenz or Atazanavir/Ritonavir Given With Emtricitabine/Tenofovir Disoproxil Fumarate or Abacavir/Lamivudine in HIV Infected Treatment-Naive Adults

HIV Infections

United States, Puerto Rico
Grünenthal GmbH

Terminated

A Study in Healthy Male Volunteers to Investigate the Safety and Tolerability of a Single Dose of Neosaxitoxin Alone and in Combination With Bupivacaine (With and Without Epinephrine) for Brachial Plexus Blockade

Analgesia | Anesthesia, Local | Anesthesia

Netherlands
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Combination Chemotherapy and Rituximab in Treating Patients With Newly Diagnosed Burkitt's Lymphoma or Leukemia

Lymphoma | Leukemia

United States
Henan University of Traditional Chinese Medicine
Peking University First Hospital; Chengdu University of Traditional Chinese... and other collaborators

Unknown

Study on Children Henoch-Schönlein Purpura Nephritis With TCM Multistep Treatment

Henoch-Schönlein Purpura Nephritis

China
Hoffmann-La Roche

Completed

A Study of Participant Preference With Subcutaneous Versus Intravenous MabThera/Rituxan in Participants With CD20+ Diffuse Large B-Cell Lymphoma or CD20+ Follicular Non-Hodgkin's Lymphoma Grades 1, 2 or 3a

Diffuse Large B-Cell Lymphoma, Non-Hodgkin's Lymphoma

Hong Kong, Germany, Philippines, Taiwan, Turkey, Canada, Australia, Austria, New Zealand, Thailand, Hungary, Italy, Korea, Republic of, Romania, Netherlands, Brazil, Indonesia, Croatia, Egypt, Portugal, Sweden, Colombia, Argentina, De... and more
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Cyclophosphamide and Busulfan Followed by Donor Stem Cell Transplant in Treating Patients With Myelofibrosis, Acute Myeloid Leukemia, or Myelodysplastic Syndrome

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia... and other conditions

United States
Eunice Kennedy Shriver National Institute of Child...

Completed

Evaluation of Cortisol Resistance in Young Sedentary and Endurance-Trained Men

ACTH | Glucocorticoid | Cortisol Resistance | Negative Feedback | Mineralcorticoid

United States
National Cancer Institute (NCI)

Completed

Androgen Deprivation Therapy and Vorinostat Followed by Radical Prostatectomy in Treating Patients With Localized Prostate Cancer (TARGET)

Prostate Adenocarcinoma | Stage I Prostate Cancer | Stage III Prostate Cancer | Stage IIA Prostate Cancer | Stage IIB Prostate Cancer

United States
ALK-Abelló A/S
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety Study of SCH 900237/MK-8237 in Children and Adults With House Dust Mite-Induced Allergic Rhinitis/Rhinoconjunctivitis (P05607)

Rhinitis, Allergic, Perennial | Rhinitis, Allergic, Nonseasonal
National Cancer Institute (NCI)

Completed

Temozolomide or Selumetinib in Treating Patients With Metastatic Melanoma of the Eye

Iris Melanoma | Stage IV Uveal Melanoma | Medium/Large Size Posterior Uveal Melanoma | Recurrent Uveal Melanoma | Ocular Melanoma With Extraocular Extension | Small Size Posterior Uveal Melanoma

United States, Canada
German CLL Study Group

Completed

Fludarabine and Cyclophosphamide in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Chronic Lymphocytic Leukemia or Waldenstrom's Macroglobulinemia

Chronic Lymphocytic Leukemia

Canada, Germany
George Washington University

Withdrawn

Corticosteroids Therapy and Pneumocystis Jirovecii Pneumonia (PCP)

Pneumocystis Carinii Pneumonia

United States
University of California, Davis

Completed

A Pilot Project of Virologic, Pharmacologic and Immunologic Correlates of Gastrointestinal-Associated Lymphoid Tissue Immune Reconstitution Following Maraviroc Therapy

HIV Infections

United States
Rigshospitalet, Denmark
Glostrup University Hospital, Copenhagen

Completed

The Effect of Intraoperative Ketamine on Opioid Consumption and Pain After Spine Surgery in Opioid-dependent Patients

Chronic Pain | Postoperative Pain | Analgesics

Denmark
GlaxoSmithKline

Completed

Evaluating the Control of COPD Symptoms in Patients Treated With Tiotropium Bromide 18mcg Once Daily Alone, ADOAIR 50/250mcg Twice Daily Alone or ADOAIR 50/250mcg Plus Tiotropium Bromide 18mcg

Pulmonary Disease, Chronic Obstructive

Japan
Hartford Hospital

Completed

Decreasing Narcotics in Advanced Pelvic Surgery (Pain)

Pain | Nausea | Constipation | Narcotic Use

United States
Bristol-Myers Squibb

Completed

Dasatinib in Combination With Revlimid (and Dexamethasone)

Multiple Myeloma

United States, France, Australia
University of Rochester
Mae Stone Goode Foundation

Completed

Novel Topical Therapies for the Treatment of Genital Pain (Topicals)

Female Genital Diseases

United States
University of New Mexico
Bayer; Society of Family Planning

Completed

Nitrous Oxide for Pain Management During In-office Transcervical Sterilization (NEST)

Contraception | Inhalation of Nitrous Oxide

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Pan FGFR Kinase Inhibitor BGJ398 and Combination Chemotherapy in Treating Patients With Untreated Metastatic Pancreatic Cancer

Pancreatic Adenocarcinoma | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Pancreatic Ductal Adenocarcinoma | Metastatic Pancreatic Adenocarcinoma | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Rectal Adenocarcinoma | Stage IIIA Colon Cancer | Stage IIIB Colon... and other conditions

United States
Seoul National University Hospital

Completed

Evaluation and Validation of Metabolic Markers for the Assessment of CYP3A Activity and Prediction of DDI (CYP3A_weak)

Healthy
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Chemotherapy With or Without Strontium-89 in Treating Patients With Prostate Cancer

Prostate Cancer

United States
Fox Chase Cancer Center
Genentech, Inc.

Withdrawn

Rituximab and Combination Chemotherapy in Treating Patients With Previously Untreated High- or High-Intermediate-Risk Diffuse Large B-Cell Lymphoma

Stage III Adult Diffuse Large Cell Lymphoma | Stage IV Adult Diffuse Large Cell Lymphoma | Contiguous Stage II Adult Diffuse Large Cell Lymphoma | Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma | Stage I Adult Diffuse Large Cell Lymphoma

United States
ANRS, Emerging Infectious Diseases

Completed

4 Consecutive Days on Treatment Followed by 3 Days Off Treatment, in HIV Patients (ANRS162-4D)

HIV-1 Infection

France
Asan Medical Center
Korea Otsuka Pharmaceutical Co., Ltd.

Unknown

PreventIon of IMT Progression in iSchemic Stroke Patients With High Risk of Cerebral HemOrrhage-IMT Study (PICASSO-IMT)

Brain Ischemia | Intracranial Hemorrhages
Helsinki University Central Hospital
Foundation for Paediatric Research, Finland; Päivikki and Sakari Sohlberg Foundation... and other collaborators

Completed

Aggressive Combination Drug Therapy in Very Early Polyarticular Juvenile Idiopathic Arthritis (ACUTE-JIA)

Juvenile Idiopathic Arthritis

Finland
Association Asthma, Bulgaria
Nasaleze

Unknown

4"S" - Seasonal Symptoms Suppression Study (4"S")

Seasonal Allergic Rhinitis

Bulgaria
Takeda

Completed

Treatment of Hot Flushes Caused by Leuprorelin 11.25 mg in Prostate Adenocarcinoma

Adenocarcinoma, Prostate

France
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Genetically Modified Peripheral Blood Stem Cell Transplant in Treating Patients With HIV-Associated Non-Hodgkin or Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
First Affiliated Hospital of Harbin Medical University

Unknown

The Effect of Parecoxib Sodium Intravenous Patient-controlled Analgesia in Laparotomic Liver Resection

Pain, Postoperative

China
Baskent University

Completed

Effects of Dexmedetomidine Premedication on Geriatric Patients With Chronic Renal Failure Undergoing Hip Surgery

Hip Fracture | Chronic Renal Failure

Turkey
Genentech, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Rituximab in Subjects With International Society of Nephrology/Renal Pathology Society (ISN/RPS) 2003 Class III or IV Lupus Nephritis (LUNAR)

Lupus Nephritis
Duke University

Withdrawn

Use of Recombinant Hyaluronidase Human is Effective for the Use of Local Blocks for Eyelid's Surgery

Upper Eyelid Surgery

United States
Tyumen State Medical Academy

Unknown

Hemocoagulation and Lipoperoxidation in Women Using Combined Oral Contraceptives, Correction by Antioxidants

Hyperandrogenism | Polycystic Ovarian Syndrome | Menstrual Irregularities

Russian Federation
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Two Regimens of Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed Localized Ewing Sarcoma Family of Tumors

Ewing Sarcoma of Bone | Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor

United States
Stanford University
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy +/- Radiation in High Risk Hodgkin's Disease

Hodgkin Disease

United States
Repros Therapeutics Inc.

Completed

Open-Label, Multiple-Dose, Non-Randomized Study to Assess Drug-Drug Interactions of Proellex® in Female Subjects

Drug Interactions

United States
National Cancer Institute (NCI)
Eastern Cooperative Oncology Group; NCIC Clinical Trials Group; Cancer and Leukemia... and other collaborators

Terminated

Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With Metastatic Colorectal Cancer That Progressed During First-Line Therapy

Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal Cancer

United States
Boehringer Ingelheim

Completed

Relative Bioavailability of Different Oral Viramune Extended Release Formulations Compared to Viramune® Oral Suspension in Healthy Male Volunteers

Healthy
Tang-Du Hospital

Unknown

Effects of Dexmedetomidine on Postoperative Cognitive Dysfunction During One-lung Ventilation in Elder Patients

Postoperative Confusion
Magna Pharmaceuticals, Inc.

Unknown

StahistRx Phase 2, Five-arm, Parallel Group, Active vs Active, Double-blind Study

Rhinitis, Seasonal, Allergic

United States
University of Southern California

Completed

Intensified Post Remission Therapy Containing PEG-Asparaginase

Acute Lymphoblastic Leukemia

United States
Yonsei University

Withdrawn

A Randomized, Open-label Study on Helicobacter Pylori Eradication With Standard Triple Regimen Plus Acetazolamide

H. Pylori Infection

Korea, Republic of
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy and Radiation Therapy in Treating Children With Previously Untreated Stage II, Stage III, or Stage IV Hodgkin's Disease

Lymphoma

United States, Australia, Canada
FLUIDDA nv

Completed

Compare the Effects of Seretide® Evohaler and a Generic Salmeterol/Fluticasone Hydrofluoroalkane (HFA) Pressurized Metered-dose Inhaler (pMDI) on Functional Respiratory Imaging Parameters in Asthmatic Patients

Asthma

Belgium
Azienda Ospedaliero-Universitaria di Modena

Unknown

Combination Chemotherapy and Trastuzumab in Treating Women With Stage I, Stage II, or Stage III HER2-Positive Breast Cancer

Breast Cancer

Italy

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