Search clinical trials for: APN401

Total 65 results

Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

APN401 in Treating Patients With Recurrent or Metastatic Pancreatic Cancer, Colorectal Cancer, or Other Solid Tumors That Cannot Be Removed by Surgery

Recurrent Pancreatic Carcinoma | Stage IV Pancreatic Cancer | Recurrent Colorectal Carcinoma | Unresectable Solid Neoplasm | Metastatic Malignant Neoplasm in the Brain | Metastatic Solid Neoplasm | Recurrent Solid Neoplasm | Stage IV Colorectal Cancer | Stage IVA Colorectal Cancer | Stage IVA Pancreatic... and other conditions

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

APN401 in Treating Patients With Melanoma, Kidney Cancer, Pancreatic Cancer, or Other Solid Tumors That Are Metastatic or Cannot Be Removed By Surgery

Unspecified Adult Solid Tumor, Protocol Specific | Stage III Renal Cell Cancer | Recurrent Melanoma | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Stage IV Melanoma | Stage IV Renal Cell Cancer | Recurrent Renal Cell Cancer | Stage IIIA Melanoma | Stage IIIB Melanoma and other conditions

United States
invIOs GmbH

Recruiting

PBMC-based Leukocyte Immunotherapy (PALINDROM)

Advanced Solid Tumor

Austria
Abion Inc
Novotech (Australia) Pty Limited

Recruiting

To Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of ABN401 in Patients With Advanced Solid Tumors and Non-Small Cell Lung Cancer Harboring c-MET Dysregulation

Advanced Solid Tumors

Australia, Korea, Republic of
Abion Inc

Recruiting

To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetic Profile of ABN401 in Patients With Advanced Solid Tumors Harboring c-MET Dysregulation

Advanced Solid Tumors

Korea, Republic of, Taiwan, United States
Yonsei University

Not yet recruiting

A Phase II Study of ABN401 in Advanced Solid Tumors With c-MET Gene Aberration

Neoplasms
Basilea Pharmaceutica

Completed

Study to Assess Safety, Tolerability and Pharmacokinetics of APX001 Administered by Intravenous Infusion to Healthy Subjects

Fungal Infection

Netherlands
Apeiron Biologics

Completed

Study of APN201 (Liposomal Recombinant Human Cu/Zn-Superoxide Dismutase) for the Prevention of Radiation-induced Dermatitis in Women With Breast Cancer

Radiation Induced Dermatitis

Austria
Basilea Pharmaceutica

Completed

Safety, Pharmacokinetics, Bioavailability, Food Effect, Drug-Drug Interaction Study of APX001 Administered Orally

Fungal Infection

Netherlands
Apeiron Biologics

Completed

Recombinant Human Angiotensin-converting Enzyme 2 (rhACE2) as a Treatment for Patients With COVID-19 (APN01-COVID-19)

COVID-19

Denmark, Germany, Austria, Russian Federation, United Kingdom
Abion Inc

Completed

To Evaluate the Safety, Pharmacokinetic and the Effect of Food After Administration of ABN401 in Healthy Adult Volunteers

Solid Tumor

Korea, Republic of
Acacia Pharma Ltd

Completed

Dose-ranging Study of APD405 in Post-operative Nausea and Vomiting (PONV)

Postoperative Nausea and Vomiting

United States, Switzerland, Germany, France
Basilea Pharmaceutica

Completed

An Open-label Study of APX001 for Treatment of Patients With Candidemia/Invasive Candidiasis Caused by Candida Auris (APEX)

Candidemia | Candida Infection | Invasive Candidiases

South Africa
Acacia Pharma Ltd

Completed

Mass-balance Study of [14C]-APD421 in Healthy Volunteers

Post-operative Nausea and Vomiting

Netherlands
Acacia Pharma Ltd

Completed

Phase II Dose-ranging Study of APD421 in PONV

Postoperative Nausea and Vomiting

United States, Germany, France
CANbridge Life Sciences Ltd.

Recruiting

Phase 2 Study of CAN008 in Subjects With GBM

Newly-diagnosed Glioblastoma

China
Basilea Pharmaceutica

Terminated

Open-label Study of APX001 for Treatment of Patients With Invasive Mold Infections Caused by Aspergillus or Rare Molds (AEGIS)

Invasive Fungal Infections

Israel, Germany, United States, Belgium
Wellstat Therapeutics

Approved for marketing

Uridine Triacetate as Antidote for Patients at Excess Risk of 5-FU Toxicity Due to Overdosage or Impaired Elimination

Toxicity Due to Chemotherapy
Curon Biopharmaceutical (Australia) Co Pty Ltd
Novotech (Australia) Pty Limited

Terminated

A Study of CN1 in Combination With CN401 in Adult Patients With Relapsed/Refractory Lymphoid Malignancies

Relapsed Lymphoid Malignancies | Refractory Lymphoid Malignancies

Australia
Alebund Pty Ltd

Completed

A Pharmacodynamic Effect Study of AP301 in Healthy Volunteers

Healthy Subjects

Australia
CannaXan GmbH

Completed

Clinical Trial on Pharmacokinetic and Tolerability of AP701

Tolerability | Safety | Pharmacokinetic

Germany
Basilea Pharmaceutica

Completed

A Study to Assess the Mass Balance Recovery and Metabolite Profile & Identification of [14C]-APX001 in Healthy Males

Fungal Infection

United Kingdom
HK inno.N Corporation

Completed

Clinical Trial to Evaluate the Safety and Efficacy of IN-C006 Peri Inj. Compared With RPN301

Parenteral Nutrition

Korea, Republic of
Wellstat Therapeutics

Completed

Open-Label Study of Uridine Triacetate in Pediatric Patients With Hereditary Orotic Aciduria

Hereditary Orotic Aciduria

United States
Apeiron Biologics

Completed

Safety and Tolerability Study of APN01 (Recombinant Human Angiotensin Converting Enzyme 2)

Cardiovascular Diseases | Kidney Diseases | Pulmonary Diseases | Cancer Diseases

Switzerland
Apogenix GmbH

Completed

APG101 in Glioblastoma

Glioblastoma Multiforme

Austria, Germany
Peking University Cancer Hospital & Institute

Recruiting

PD-L1 Targeting Nanobody Probe for PET Imaging of Solid Tumor

Melanoma | Lung Cancer | PD-L1 | PET/CT

China
Acacia Pharma Ltd

Completed

Phase II Proof-of-concept Study of APD421

Chemotherapy-induced Nausea and Vomiting

Denmark, United Kingdom
Apogenix GmbH

Completed

APG101 in Myelodysplastic Syndrome (APG101 in MDS)

Myelodysplastic Syndrome

Germany
Basilea Pharmaceutica

Completed

An Efficacy and Safety Study of APX001 in Non-Neutropenic Patients With Candidemia

Candidemia

Germany, United States, Israel, Spain, Belgium
CANbridge Life Sciences Ltd.

Completed

A Study of CAN008 for Newly Diagnosed Glioblastoma Multiforme

Glioblastoma Multiforme

Taiwan
Asana BioSciences

Terminated

Safety, Preliminary Efficacy and Pharmacokinetics of ASN001 in Metastatic Castrate Resistant Prostate Cancer

Prostate Cancer | Cancer of the Prostate | Neoplasms, Prostate | Prostatic Cancer | Neoplasms, Prostatic | Prostate Neoplasms, Castration-resistant

United States
Basilea Pharmaceutica

Completed

A Bioequivalence Study of APX001 High-load and Low-load Tablets

Invasive Fungal Infections

United States
Acacia Pharma Ltd

Completed

Study of APD421 as PONV Treatment (Prior Prophylaxis)

Postoperative Nausea and Vomiting

United States, Germany, France
Acacia Pharma Ltd

Completed

European Phase III Study of APD421 in PONV

PONV

France, Germany
Acacia Pharma Ltd

Completed

Study of APD421 as PONV Treatment (no Prior Prophylaxis)

Postoperative Nausea and Vomiting

United States, Germany, France
Apeptico Forschung und Entwicklung GmbH

Completed

Study in Intensive Care Patients to Investigate the Clinical Effect of Repetitive Orally Inhaled Doses of AP301 on Alveolar Liquid Clearance in Acute Lung Injury

Acute Lung Injury

Austria
ProtAffin Biotechnologie AG

Terminated

A Phase 1, First in Human Study to Investigate the Safety and Tolerability of PA401

Healthy Volunteers

United Kingdom
Acacia Pharma Ltd

Completed

Phase IIIb Study of APD421 in Combination as PONV Prophylaxis

PONV

United States, Germany, France
POZEN

Completed

PK Study to Evaluate Esomeprazole Plasma Levels Following Administration of PN 400

Healthy
Origin Inc.

Completed

APT001 Plasma/NO Generator to Treat Diabetic Foot Ulcer in Adults (APT-14-002)

Foot Ulcer, Diabetic

United States
Kyberg Vital GmbH

Completed

Dietary Intervention of Stress-Induced Neurovegetative Disorders With a Specific Amino Acid Composition (asn01) (asn01)

Nervous System Disorder | Imbalance of Constituents of Food Intake

Germany
POZEN

Completed

Study Evaluating the Effect of Food on the Bioavailability of PN400 Components

Arthritis

United States
Bitop AG

Completed

Safety and Efficacy of Ectoin Allergy Nasal Spray and Ectoin Allergy Eye Drops in the Treatment of Seasonal Allergic Rhinitis (SAR) in Children and Adolescents

Seasonal Allergic Rhinitis | Seasonal Allergic Conjunctivitis

Germany
Apeptico Forschung und Entwicklung GmbH

Recruiting

Safety and Preliminary Efficacy of Sequential Multiple Ascending Doses of Solnatide to Treat Pulmonary Permeability Oedema in Patients With Moderate-to-severe ARDS

ARDS

Austria, Germany
AstraZeneca
POZEN

Completed

A Study Assessing Inhibition of Serum Thromboxane B2 Levels With PN400 and Low Dose Aspirin

Platelet Inhibition

United States
Acacia Pharma Ltd

Completed

Thorough QT Study of Intravenous Amisulpride

Healthy
Acacia Pharma Ltd

Completed

Dose-finding Study of APD403 to Prevent Nausea and Vomiting After Chemotherapy

CINV

Denmark
Acacia Pharma Ltd

Completed

Study of APD421 With and Without Ondansetron

Postoperative Nausea and Vomiting

United Kingdom
Acacia Pharma Ltd

Completed

US Phase III Study of APD421 in PONV

PONV

United States

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