- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00599404
PK Study to Evaluate Esomeprazole Plasma Levels Following Administration of PN 400
April 23, 2008 updated by: POZEN
An Open-Label, 2-Period Pharmacokinetic Study to Evaluate the Intra-Subject Variability in Esomeprazole Plasma Levels in Healthy Subjects Following Oral Administration of PN 400 Tablets
Pharmacokinetic study in healthy subjects with single and repeat b.i.d.
dosing of PN 400 tablets from the same drug product batch.
Study Overview
Study Type
Interventional
Enrollment (Actual)
18
Phase
- Phase 1
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 55 years (Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
Healthy male or non-pregnant female subjects between 18-55 years of age as well as other standard inclusion criteria for a study of this nature
Exclusion Criteria:
Standard inclusion criteria for a study of this nature
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Basic Science
- Allocation: N/A
- Interventional Model: Single Group Assignment
- Masking: None (Open Label)
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Pharmacokinetic profile following dosing with PN400
Time Frame: 24-hour PK on Day 1 & Day 10 of each treatment period
|
24-hour PK on Day 1 & Day 10 of each treatment period
|
Secondary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
To evaluate the safety of PN400
Time Frame: Day 1-10 of each treatment period
|
Day 1-10 of each treatment period
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
January 1, 2008
Primary Completion (Actual)
February 1, 2008
Study Completion (Actual)
February 1, 2008
Study Registration Dates
First Submitted
January 11, 2008
First Submitted That Met QC Criteria
January 22, 2008
First Posted (Estimate)
January 23, 2008
Study Record Updates
Last Update Posted (Estimate)
April 30, 2008
Last Update Submitted That Met QC Criteria
April 23, 2008
Last Verified
April 1, 2008
More Information
Terms related to this study
Keywords
Other Study ID Numbers
- PN400-111
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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