Search clinical trials for: Aflibercept [Eylea]

Total 502 results

Bayer
Regeneron Pharmaceuticals

Completed

VEGF Trap-Eye in Choroidal Neovascularization Secondary to Pathologic Myopia (mCNV) (Myrror)

Myopia, Pathological

Japan, Taiwan, Hong Kong, Korea, Republic of, Singapore
Sanofi
Regeneron Pharmaceuticals

Completed

Aflibercept in Combination With Docetaxel in Metastatic Androgen Independent Prostate Cancer (VENICE)

Prostatic Neoplasms | Neoplasm Metastasis

United States, France, Canada, Brazil, Russian Federation, Ukraine, Australia, Netherlands, Portugal, Spain, Sweden, Switzerland, Turkey, Estonia, Singapore, Taiwan, Belgium, Czech Republic, Argentina, Denmark, Hungary, Israel, Italy, United Kingdom and more
Norwegian University of Science and Technology

Terminated

A Study Testing if Medicine Can Make Pigment Epithelium Detachments Regress and Stabilize the Vision in Eyes

Macular Degeneration | Retinal Detachment

Norway
Retinal Consultants of Arizona
Ophthotech Corporation

Completed

An Open-Label Investigator Sponsored Trial to Investigate the Safety, Tolerability and Development of Subfoveal Fibrosis By Intravitreal Administration of Altering Regimens of Fovista and Anti-VEGF Therapy in Subjects With Neovascular Age-Related Macular Degeneration

Neovascular Age-Related Macular Degeneration

United States
Innovent Biologics (Suzhou) Co. Ltd.

Completed

Trial to Evaluate the Safety and Tolerability of Repeated Intravitreal Injection of IBI302 in Neovascular AMD Patients

Neovascular Age-related Macular Degeneration

China
Lindner Center of HOPE
University of Cincinnati; Eisai Inc.

Completed

Zonegran in the Treatment of Binge Eating Disorder Associated With Obesity

Binge Eating Disorder Associated With Obesity

United States
Dar El Oyoun Hospital

Completed

Eplerenone, Aflibercept and Topical Nepafenac Serous Foveal Deta Chment in Central Serous Chorioretinopathy (CSCR)

Central Serous Chorioretinopathy

Egypt
Tianjin Medical University Eye Hospital
Abbvie Pharmaceutical Trading (Shanghai) Co., Ltd.

Recruiting

Compare the Efficacy of VItrectomy Combined With DExamethasone Implant Versus With Aflibercept in DME Patients Diagnosed by Intraoperative OCT (the VIDEO Study): Study Protocol for a Randomized Controlled Trial

Diabetic Macular Edema | Pars Plana Vitrectomy | Dexamethasone Intravitreal Implant | Intraoperative Optical Coherence Tomography

China
European Organisation for Research and Treatment...
Sanofi

Withdrawn

Efficacy of FOLFOX Versus FOLFOX Plus Aflibercept in K-ras Mutant Patients With Resectable Liver Metastases (BOS3)

Colorectal Cancer Metastatic | Liver Metastases | KRAS Mutated Colorectal Cancer
Pradeepa Yoganathan
Unity Health Toronto

Withdrawn

Combination OZURDEX® & EyLea® vs. OZURDEX® Monotherapy in IncompLete-Responders wIth Diabetic Macular Edema (COLLIDE)

Diabetic Macular Edema
Hoffmann-La Roche

Withdrawn

A Study Of The Effectiveness And Safety Of A 36-Week Refill Regimen For The Port Delivery System With Ranibizumab Vs Aflibercept Treat & Extend In Subjects With Neovascular Age-Related Macular Degeneration (Diagrid)

Neovascular Age-Related Macular Degeneration

Denmark, Argentina, Hong Kong, Thailand, Portugal, Greece, Spain
AIO-Studien-gGmbH
Sanofi; Institut für Klinisch-Onkologische Forschung (IKF) Frankfurt

Completed

mFOLFOX6 vs. mFOLFOX6 + Aflibercept as Neoadjuvant Treatment in MRI-defined T3-rectal Cancer

Rectal Cancer | Rectosigmoid Cancer

Germany
National Cancer Institute (NCI)

Completed

Se-Methyl-Seleno-L- Cysteine (MSC) in Treating Healthy Patients

Healthy, no Evidence of Disease

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Paclitaxel, Topotecan, and Cisplatin in Treating Patients With Advanced, Persistent, or Recurrent Cervical Cancer

Cervical Cancer
Onxeo
Spectrum Pharmaceuticals, Inc

Completed

Belinostat, Carboplatin and Paclitaxel (BelCaP) Compared to Carboplatin and Paclitaxel in Patients With Cancer of Unknown Primary

Carcinoma of Unknown Primary

United States, Germany, France, Denmark
Ocular Therapeutix, Inc.
Duke University; Fortrea

Recruiting

Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Ocular Therapeutix) (Axitinib Implant) in Subjects With Neovascular Age-Related Macular Degeneration

Neovascular Age-Related Macular Degeneration

United States
Graybug Vision

Completed

A Depot Formulation of Sunitinib Malate (GB-102) in Subjects With Neovascular (Wet) Age-related Macular Degeneration

Neovascular Age-Related Macular Degeneration

United States
University of Cincinnati

Unknown

N-acetylcysteine in the Treatment of Depressive Symptoms in Bipolar Offspring

Depression

United States
National Jewish Health
American Thoracic Society

Completed

The Effect of N-Acetyl-L-Cysteine, on Inflammatory and Oxidative Stress Markers in Pulmonary Sarcoidosis

Pulmonary Sarcoidosis

United States
Beni-Suef University

Completed

The Effect of N-acetylcysteine on Oxidative Stress Status and Iron Overload in Thalassemia Major

Thalassemia Major

Egypt
University of Oxford

Completed

Glutathione Levels and Compulsivity

Anorexia Nervosa | Compulsive Behavior

United Kingdom
James J Lee
Sanofi

Withdrawn

A Phase II Study of Ziv-aflibercept in Combination With Capecitabine/Oxaliplatin (XELOX) Chemotherapy in the Front-Line Treatment of Patients With Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

United States
University of Texas Southwestern Medical Center

Completed

Nifedipine for Acute Tocolysis of Preterm Labor (Nifedipine)

Preterm Labor

United States
Martin Lan

Completed

Brain Imaging to Understand the Role of Inflammation in N-Acetyl Cysteine (NAC) Treatment of Bipolar Depression

Depression | Bipolar Disorder

United States
Regeneron Pharmaceuticals
Sanofi

Terminated

A Study of Aflibercept Administered in Combination With Pemetrexed and Cisplatin in Participants With Advanced Carcinoma

Non-small Cell Lung Cancer | Advanced Carcinoma

United States, Canada
Cancer Research UK

Unknown

Combination Chemotherapy in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer

Lung Cancer

United Kingdom
Royan Institute

Completed

NAC Effect on Hox Genes Expressions in RIF

Female Infertility
Sanofi

Completed

A Prospective Observational Cohort Study Evaluating Resection Rate in Patients With Metastatic Colorectal Cancer Treated With Aflibercept in Combination With FOLFIRI - Observatoire résection

Metastatic Colorectal Cancer | Colorectal Neoplasms
Rajagopal V Sekhar
National Institute on Aging (NIA)

Completed

Glutathione and Fuel Oxidation in Aging

Aging

United States
Federation Francophone de Cancerologie Digestive

Active, not recruiting

Standard Chemotherapy vs Immunotherapie in 2nd Line Treatment of MSI Colorectal Mestastatic Cancer (SAMCO)

Metastatic Colorectal Cancer | MSI

France
The Lymphoma Academic Research Organisation
Millennium Pharmaceuticals, Inc.

Completed

Brentuximab Vedotin Associated With Chemotherapy in Untreated Patients With Hodgkin Lymphoma. (BREACH)

Hodgkin Lymphoma

Netherlands, France, Belgium, Croatia, Denmark
Nemours Children's Clinic

Completed

Fatty Liver Disease in Obese Children

Obesity | Cardiovascular Disease | Nonalcoholic Fatty Liver Disease

United States
University of Cologne

Completed

Adriamycin, Vinblastine, DTIC and Revlimid in Elderly Hodgkin Lymphoma Patients (AVD-Rev)

Hodgkin Lymphoma

Germany
Assiut University

Completed

N-acetyl Cysteine for Ovulation Induction in Clomiphene Citrate Resistant Polycystic Ovary Syndrome

Polycystic Ovary Syndrome
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Withdrawn

A Multi-Center Phase 2 Study of VEGF Trap as a Single Agent in Acute Myeloid Leukemia

Leukemia
Sanofi
Regeneron Pharmaceuticals

Completed

A Study of Aflibercept in Combination With FOLFIRI in Patients With Second-Line Metastatic Colorectal Cancer in Japan

Colorectal Cancer Metastatic

Japan
Universidad Autónoma de Bucaramanga
Fundación Cardioinfantil Instituto de Cardiología; Instituto Nacional de Salud... and other collaborators

Unknown

CHICAMOCHA 3 - Equivalence of Usual Interventions for Trypanosomiasis (EQUITY) (CHICAMOCHA-3)

Chagas Disease

Colombia
Grupo Espanol Multidisciplinario del Cancer Digestivo
Pivotal S.L.

Completed

Induction FOLFOX With or Without Aflibercept Followed by Chemoradiation in High Risk Locally Advanced Rectal Cancer (RIA)

Rectal Cancer
John Hays
Sanofi

Unknown

Aflibercept and FOLFOX6 Treatment for Previously Untreated Stage IV Colorectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IV Colon Cancer | Stage IV Rectal Cancer

United States
Università degli Studi di Brescia

Completed

Nutraceutical Support With Omega-3

Retinal Disease
Spanish Cooperative Group for the Treatment of...
Sanofi

Completed

Study to Assess the Efficacy and Safety of Treatment With FOLFIRI-aflibercept Compared to Initial Treatment With FOLFIRI-aflibercept (for 6 Cycles) Followed by Maintenance With 5FU-aflibercept, in an Elderly Population With mCRC After Failure of an Oxaliplatin-based Regimen (AFEMA)

Metastatic Colorectal Cancer

Spain
Hellenic Oncology Research Group

Unknown

Trial in Metastatic Colorectal Cancer With FOLFIRI Plus Aflibercept as First Line Treatment (MINOAS)

Metastatic Colorectal Cancer

Greece
Vitrolife

Completed

Adding Antioxidants Into Human Sequential Culture Media System (Antioxidants)

Blastocyst | Human | Antioxidants | Oxygen | Culture Media | Embryo

Japan
Charles Drew University of Medicine and Science

Completed

The Effects of a Glutathione Precursor (FT061452),on Serum and Intracellular Glutathione Levels

Oxidative Stress

United States
A. Manzoni Hospital

Completed

"Steroids and Azathioprine Versus Steroids Alone in IgAN"

IGA Nephropathy

Switzerland, Italy
Retina Vitreous Associates of Florida

Completed

Anesthesia Preference for Intravitreal Injection: Topical or Subconjunctival

Age-related Macular Degeneration | Central Retinal Vein Occlusion | Diabetic Macular Edema

United States
Chiesi SAS
Kappa Santé

Recruiting

Impact of Fixed TRIple Therapy With Beclometasone/Formoterol/Glycopyrronium DPI (Trimbow® in NEXThaler Device) in Chronic Obstructive PulmoNary Disease in rEal-world Settings: Health-related Quality of Life Patient' eXpectations and characterisTics: the TriNEXT Study (TriNEXT)

COPD

France
Merck Sharp & Dohme LLC

Terminated

Conventional Step-Up Versus Infliximab Monotherapy in Patients With Ulcerative Colitis (P05553) (MUNIX)

Colitis, Ulcerative
European Organisation for Research and Treatment...
Medical Research Council

Completed

Radiation Therapy With or Without Chemotherapy After Surgery in Treating Patients With Stage IB or Stage IIA Cervical Cancer

Cervical Cancer

United Kingdom
Bp Consulting, Inc

Completed

Determination of Optimum Duration of Treatment With Bromfenac (Xibrom) Eyedrops Following Cataract Surgery

Cataracts

United States

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