Search clinical trials for: Antihypertensive Agents

Total 187722 results

University of Florida

Completed

Pharmacogenomic Evaluation of Antihypertensive Responses in Induced Pluripotent Stem (iPS) Cells Study (PEAR-iPSC)

Hypertension

United States
Glaukos Corporation

Completed

Prospective Evaluation of Open-Angle Glaucoma Subjects on One Topical Hypotensive Medication Treated With Two iStents

Subjects With Primary Open-angle Glaucoma (POAG)

Armenia
Novartis

Completed

A Clinical Study to Evaluate the Safety and Efficacy of the Combination of Aliskiren and Valsartan in Hypertensive Non Responders Patients

Hypertension

United States, Germany
Novartis

Completed

Effects of Aliskiren, Irbesartan, and the Combination in Hypertensive Patients With Type 2 Diabetes and Diabetic Nephropathy

Diabetes Type 2

Denmark
Central Hospital, Nancy, France

Completed

Stopping Antihypertensive Treatment amOng Hypertensive Patients in Primary Care (STOP-Trial)

Hypertension

France
Glaukos Corporation

Completed

Prospective Evaluation of Open-angle Glaucoma Subjects on Two Topical Hypotensive Medication Treated With Two iStents

Subjects With Primary Open-angle Glaucoma (POAG)

Armenia
Centre Hospitalier Universitaire de Nice

Unknown

Study of the Benefit of Early Treatment With an Endothelin Inhibitor (Bosentan) in Patients With Sudden Blindness Due to Giant Cell Arteritis: CECIBO (CECIBO)

Arteritis, Giant Cell | Blindness and Low Vision

France
Novartis

Completed

A Clinical Study to Evaluate the Safety and Efficacy of Aliskiren Alone and in Combination With Ramipril in Hypertensive, Diabetic Patients.

Hypertension, Diabetes Mellitus

United States, Germany
Novartis

Completed

Efficacy and Safety of Aliskiren 300mg Compared to Irbesartan 300mg and Ramipril 10 mg in the Setting of a Missed Dose for Patients With Essential Hypertension.

Essential Hypertension

Switzerland, Germany
Meditor Pharmaceuticals Ltd.

Withdrawn

Pharmacokinetics and Pharmacodynamics of MTR105 in Hypotensive Cardiac Surgery Patients

Hypotension | Cardiopulmonary Bypass

United States
University Hospital, Strasbourg, France

Withdrawn

Clonidine and Left Ventricular Dysfunction

Ventricular Dysfunction
Shanghai 10th People's Hospital

Completed

A Prospective Cohort Study of China Serum Uric Acid Levels (ASSURE)

Uric Acid Serum
Beijing Tiantan Hospital

Not yet recruiting

Folic Acid and Intensive Antihypertensive Therapy for Hypertension With CSVD (FAITH)

Stroke | Cerebral Small Vessel Diseases

China
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Control of Hypertension by Non-Pharmacologic Means

Heart Diseases | Cardiovascular Diseases | Vascular Diseases | Hypertension
University of Minnesota
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Multiple Risk Factor Intervention Trial for the Prevention of Coronary Heart Disease (MRFIT)

Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Coronary Disease
Cairo University

Not yet recruiting

Radiofrequency in Female Pattern Hair Loss

Female Pattern Baldness
Organon and Co

Completed

A Study to Evaluate Whether Losartan Protects the Kidney in Hypertensive Diabetic Participants With Microalbuminuria (MK0954-365 AM1)

Hypertension
Novartis

Completed

A Clinical Study to Assess Efficacy and Safety of Aliskiren in the Elderly With High Blood Pressure

Hypertension

Switzerland
London School of Hygiene and Tropical Medicine
University College, London

Completed

Cardiovascular Medication Use Before First Myocardial Infarction

Myocardial Infarction

United Kingdom
Novartis

Completed

Long Term Safety of Aliskiren Alone or With the Optional Addition of Hydrochlorothiazide in Patients With Essential Hypertension

Hypertension

Germany
Novartis

Completed

A Clinical Study to Compare the Safety and Efficacy of an Aliskiren-based Regimen With a Lisinopril Based Regimen in Patients With Severe Hypertension

Hypertension

Switzerland, Spain, Hungary, Germany
Wake Forest University Health Sciences

Active, not recruiting

Pediatric Primary Hypertension and the Renin-Angiotensin System (PHRAS) (PHRAS)

Pediatric Obesity | Pediatric Disorder | Primary Hypertension

United States
Boryung Pharmaceutical Co., Ltd

Completed

Fimasartan and Rosuvastatin for Hypertension and Dyslipidemia Control (FIMARO)

Cardiovascular Diseases | Hyperlipidemias

Korea, Republic of
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Selara Drug Use Investigation (Regulatory Post Marketing Commitment Plan) (ESSENCE)

Hypertension
University of Lausanne Hospitals

Terminated

Bosentan in Myocardium Metabolism and Perfusion Measured by 18F-FDG and 82Rb PET/CT on PAH and CTEPH

Endothelial Dysfunction | Myocardial Dysfunction

Switzerland
Quantum Genomics SA

Completed

Novel Evaluation With QGC001 in Hypertensive Overweight Patients of Multiple Ethnic Origins (NEW-HOPE)

Hypertension

United States
IlDong Pharmaceutical Co Ltd

Unknown

Post Marketing Surveillance of Telostop TAB (Telmisartan/Rosuvastatin) for Evaluating the Safety and Efficacy

Hypertension | Dyslipidemias
Novartis

Completed

Clinical Study to Evaluate the Efficacy and Safety of Aliskiren Alone and in Combination With Hydrochlorothiazide in Patients With Essential Hypertension.

Hypertension

Germany, United States
Closter Pharma

Unknown

Real-life Experience of the Use of Isomers as METPURE XL (S (-) Metoprolol Succinate) for Evaluation of Efficacy, Safety and Tolerability in the Management of Cardiovascular Disease in Colombian Patients (XPERT)

Coronary Disease | Hypertension

Colombia
Liquidia Technologies, Inc.

Recruiting

An Open-Label ProSpective MultiCENTer Study to Evaluate Safety and Tolerability of Dry Powder Inhaled Treprostinil in PH (ASCENT)

Pulmonary Hypertension | Interstitial Lung Disease

United States
Hospital de Base
Sao Jose do Rio Preto Medical School

Recruiting

Evaluation of Intestinal Microbiota Manipulation to Treat Resistant Hypertension (VALORIS)

Hypertension | Resistant Hypertension

Brazil
University of Copenhagen
Lundbeck Foundation; Danish Council for Independent Research

Completed

Impact of Aerobic Exercise Training on Sympathetic Vasoconstriction and Vascular Function in Essential Hypertension (IMPROVEH)

Hypertension,Essential

Denmark
Glaukos Corporation

Completed

Purpose of This Study is to Evaluate the Safety and Efficacy of One, Two, or Three iStents for the Reduction of Intraocular Pressure in Open-angle Glaucoma Subjects

Primary Open Angle Glaucoma (POAG)

Armenia
Zhang Lei

Completed

Hypertension and Controlled Hypotension in the Elderly

Delirium

China
The Young Investigator Group of Cardiovascular...

Completed

The Effects of Sacubitril/Valsartan on the Heart Functions

Drug Effect
Nete Hornnes

Completed

Prevention After Stroke - a Nurse-led Physician-supervised Model

Stroke
Novartis

Completed

Clinical Study to Evaluate Efficacy and Safety of Aliskiren (150mg & 300mg) Administered Alone and in Combo With Valsartan (160mg and 320mg) in Patients With High Blood Pressure

Hypertension

United States, Germany
Huai'an No.1 People's Hospital

Completed

Continuous Monitoring Nocturnal Beat-to-beat Blood Pressure Fluctuation in OSA With or Without Hypertension

Blood Pressure Disorders

China
Boryung Pharmaceutical Co., Ltd
Samsung Medical Center; Asan Medical Center; Seoul National University Hospital; Seoul National University Bundang Hospital and other collaborators

Completed

Antihypertensive Efficacy and Tolerability and Determine the Adequate Antihypertensive Dosage of Fimasartan in Mild to Moderate Essential Hypertension Patients

Hypertension

Korea, Republic of
University of Calgary
Actelion

Completed

First-line Bosentan and Sildenafil Combination Therapy for Pulmonary Arterial Hypertension

Hypertension, Pulmonary

Canada
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Hypertension Detection and Follow-up Program (HDFP)

Heart Diseases | Cardiovascular Diseases | Vascular Diseases | Hypertension
Cheng LuFeng,Principal Investigator
First Affiliated Hospital of Xinjiang Medical University

Not yet recruiting

Clinical Study on the Immunomodulatory Effect of Eprolidone on Patients With Chronic Heart Failure

Chronic Heart Failure Patients
Novartis

Completed

A Clinical Study to Evaluate Safety & Efficacy of the Combination of Aliskiren, Valsartan & Hydrochlorothiazide in Diabetic Hypertensive Nonresponder Patients

Hypertension | Diabetes

Switzerland, Sweden, Romania, Belgium, Spain, United States, Ukraine
Novartis

Completed

A Clinical Study to Compare an Aliskiren Based Hypertensive Regimen With a Ramipril Based One Followed by a Randomized Withdrawal.

Hypertension

United States
Novartis

Completed

A Clinical Study to Evaluate the Long-term Safety (12 Months) of the Combination of Aliskiren 300 mg and Hydrochlorothiazide 25 mg

Hypertension

United States, Belgium, Canada, Germany, Italy, Netherlands, Peru, Russian Federation, Switzerland, United Kingdom
University of Colorado, Denver

Completed

The Diurnal and Nocturnal Effect of Simbrinza and Timolol on Intraocular Pressure and Ocular Perfusion Pressure

Ocular Hypertension | Open Angle Glaucoma | Pseudoexfoliation Glaucoma | Pigment Dispersion Syndrome

United States
Universitaire Ziekenhuizen KU Leuven

Completed

Impact of a Tolerability Switch to Dorzolamide/Timolol Preservative-free Fixed Combination on Ocular Surface Symptoms

Open Angle Glaucoma

Belgium
Elpen Pharmaceutical Co. Inc.

Withdrawn

Efficacy and Safety of Upfront Combination of ΒΟsentan and ΤΑdalafil in Pulmonary Arterial Hypertension (BOTA-PAH)

Pulmonary Hypertension
Children's Healthcare of Atlanta

Completed

Eisenmenger's Syndrome in Adults With CHD

Congenital Disorders

United States
Children's Healthcare of Atlanta

Completed

Pulmonary Hypertension in Trisomy 21 Patients

Congenital Disorders

United States

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