Search clinical trials for: Atovaquone

Total 52 results

Radboud University Medical Center
Leiden University Medical Center

Completed

Re-exposure of Human Volunteers to a Heterologous Strain of P. Falciparum Sporozoites (TIP4)

Malaria, Falciparum

Netherlands
Modus Therapeutics AB
University of Oxford

Terminated

Sevuparin/DF02 as an Adjunctive Therapy in Subjects Affected With Uncomplicated Falciparum Malaria

Malaria, Falciparum

Thailand
Radboud University Medical Center

Completed

Drug Interaction Study Between Atovaquone and Antiretroviral Agents in HIV-1 Infected Patients

HIV Infections | Malaria

Netherlands
National Institutes of Health Clinical Center (CC)

Completed

Antiretroviral Drug Interaction Study in Volunteers With HIV

HIV | Toxoplasmosis | PCP

United States
Armed Forces Research Institute of Medical Sciences...
National Centre for Parasitology, Entomology and Malaria Control, Cambodia; Naval Medical Research Center, Asia (NMRC-A)

Active, not recruiting

The ASAP Study - Therapeutic Efficacy of Atovaquone-proguanil vs. Artesunate-atovaquone-proguanil in Cambodia (ASAP)

Malaria

Cambodia
Assistance Publique - Hôpitaux de Paris

Completed

Evaluation of the Riamet® Versus Malarone® in the Treatment of Uncomplicated Malaria (MalaRia)

Malaria

France
GlaxoSmithKline

Completed

Single Oral Dose Study of Atovaquone/Proguanil Hydrochloride Combination Tablets and Atovaquone Suspension

Malaria

Japan
Medicines for Malaria Venture
Richmond Pharmacology Limited

Completed

Atoguanil BA Study

Bioavailability

United Kingdom
U.S. Army Medical Research and Development Command

Completed

Weekly Dosing of Malarone ® for Prevention of Malaria (MALWEEK)

Malaria

United States
Armed Forces Research Institute of Medical Sciences...
National Center for Parasitology, Entomology, and Malaria Control (CNM); Naval...

Recruiting

Drug Combinations of Atovaquone-Proguanil (AP) With ACT (APACT)

Plasmodium Falciparum Malaria (Drug Resistant)

Cambodia
University Hospital Tuebingen
Sanaria Inc.

Completed

Safety and Protective Efficacy of IV Immunization With Cryopreserved PfSPZ Under A/P Chemoprophylaxis

Malaria
Radboud University Medical Center

Completed

Immunization With Different Doses of Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis (ZonMw1)

Plasmodium Falciparum Malaria

Netherlands
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Recruiting

Efficacy, Safety, and PK of M5717 in Combination With Pyronaridine as Chemoprevention in Adults and Adolescents With Asymptomatic Plasmodium Falciparum Infection (CAPTURE-2)

Malaria Infection

Kenya, Burkina Faso, Gambia, Zambia
Medicines for Malaria Venture
Institute of Tropical Medicine, University of Tuebingen

Completed

DSM265 Chemoprophylaxis of Plasmodium Falciparum Malaria

Plasmodium Falciparum, Malaria

Germany
HonorHealth Research Institute

Terminated

Atovaquone and Azithromycin Combination for Confirmed COVID-19 Infection

Covid19

United States
Radboud University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine Versus Mefloquine Prophylaxis

Malaria | Plasmodium Falciparum

Netherlands
U.S. Army Medical Research and Development Command
Naval Medical Research Center

Withdrawn

A Clinical Trial to Evaluate Plasmodium Falciparum 7G8 and NF54 Challenge Strains (PfSPZ) in a Head-to-head Comparative Study - (ECG-CHMI) (ECG-CHMI)

Plasmodium Falciparum
Pfizer

Completed

Azithromycin Plus Chloroquine Versus Atovaquone-Proguanil For The Treatment Of Uncomplicated Plasmodium Falciparum Malaria In South America

Malaria, Falciparum
Radboud University Medical Center

Completed

Experimental Human Malaria Infection After Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis (EHMI9)

Plasmodium Falciparum Malaria

Netherlands
National Institute of Allergy and Infectious Diseases...

Completed

Chloroquine Alone or in Combination for Malaria in Children in Malawi

Plasmodium Falciparum Infection

Malawi
Novartis

Completed

Evaluation of Potential Effect of Artemether - Lumefantrine and Malaria Drugs on Auditory Function

Malaria | Falciparum

Colombia
Seoul National University Hospital

Completed

Study to Evaluate the Influence of Tegoprazan on the Pharmacokinetics of Proguanil in Healthy Volunteers

Gastroesophageal Reflux Disease

Korea, Republic of
Walter Reed Army Institute of Research (WRAIR)

Withdrawn

Malarone Pharmacokinetics Under Simulated Physiologic Stressors of Deployment (MPUSPSD)

Exercise | Pharmacokinetics

United States
Jimma University
Ludwig-Maximilians - University of Munich

Completed

Ototoxicity of Artemether / Lumefantrine (Coartem) and Other Antimalarials

Malaria

Ethiopia
Merck Sharp & Dohme LLC

Not yet recruiting

A Study to Evaluate Antimalarial Activity and Safety of MK-7602 in Healthy Adults (MK-7602-003)

Malaria
Radboud University Medical Center
Bill and Melinda Gates Foundation

Completed

Chemoprophylaxis and Plasmodium Falciparum NF54 Sporozoite Immunization Challenged by Heterologous Infection (BMGF2b)

Malaria

Netherlands
University of Oxford
Cancer Research UK; Guy's and St Thomas' NHS Foundation Trust; NHS Lothian; National... and other collaborators

Completed

Atovaquone With Radical ChemorADIotherapy in Locally Advanced NSCLC (ARCADIAN)

Locally Advanced Non-Small Cell Lung Cancer

United Kingdom
Radboud University Medical Center
The PATH Malaria Vaccine Initiative (MVI)

Terminated

Safety and Efficacy of NF135 CPS Immunization (CPS135)

Malaria,Falciparum | Controlled Human Malaria Infection | Immunization; Infection

Netherlands
National Institute of Allergy and Infectious Diseases...

Completed

Phase I Safety and Pharmacokinetics Study of Microparticulate Atovaquone (m-Atovaquone; 566C80) in HIV-Infected and Perinatally Exposed Infants and Children

HIV Infections | Pneumonia, Pneumocystis Carinii

United States, Puerto Rico
Radboud University Medical Center
Bill and Melinda Gates Foundation

Completed

Target Antigens Induced by Plasmodium Falciparum Sporozoite Immunization Under Chemoprophylaxis (BMGF1)

Malaria

Netherlands
U.S. Army Medical Research and Development Command

Withdrawn

Chloroquine (CQ) and Azithromycin (AZ) Combination for Malaria Prophylaxis

Malaria

United States
University of Oxford

Completed

Atovaquone as Tumour HypOxia Modifier (ATOM)

Carcinoma, Non-Small-Cell Lung

United Kingdom
Radboud University Medical Center
The PATH Malaria Vaccine Initiative (MVI); QIMR Berghofer Medical Research...

Completed

Controlled Human Malaria Infection Model for Evaluation of Transmission-Blocking Interventions - Study 1 (CHMI-trans1)

Malaria

Netherlands
Radboud University Medical Center
The PATH Malaria Vaccine Initiative (MVI); QIMR Berghofer Medical Research...

Completed

Controlled Human Malaria Infection Model for Evaluation of Transmission-blocking Interventions - Study 2 (CHMI-trans2)

Transmission | Malaria,Falciparum | Controlled Human Malaria Infection | Gametocytes

Netherlands
University of Texas Southwestern Medical Center

Completed

Atovaquone for Treatment of COVID-19

COVID-19

United States
Glaxo Wellcome

Completed

A Pilot Study of 566C80 for the Salvage Treatment of Toxoplasmic Encephalitis in Patients Infected With the Human Immunodeficiency Virus (HIV) Who Have Failed or Are Intolerant of Pyrimethamine-Sulfadiazine

HIV Infections | Toxoplasmosis, Cerebral

United States, Canada
Glaxo Wellcome

Completed

An Open-Label, Uncontrolled Clinical Trial of Oral 566C80 for the Treatment of Patients With Severe PCP Who Are Intolerant and/or Unresponsive to Therapy With Trimethoprim/Sulfamethoxazole and Parenteral Pentamidine

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Glaxo Wellcome

Completed

A Treatment IND for 566C80 Therapy of Pneumocystis Carinii Pneumonia

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
U.S. Army Medical Research and Development Command
Military Infectious Diseases Research Program (MIDRP)

Completed

Safety and Efficacy Study of IV Artesunate to Treat Malaria

Malaria

Kenya
Glaxo Wellcome

Completed

A Comparison of Atovaquone and Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia in HIV-Infected Patients Who Cannot Take TMP/SMX

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
State University of New York - Upstate Medical...
Walter Reed Army Institute of Research (WRAIR); Kansas State University

Completed

Effect of Antimalarial Drugs to Rabies Vaccine for Post-exposure Prophylaxis. (MALRAB)

Rabies

United States
Glaxo Wellcome

Completed

A Phase II Open Randomized Comparison of 566C80 and Pentamidine Isethionate for the Treatment of Pneumocystis Carinii Pneumonia in AIDS Patients Who Are Intolerant of Trimethoprim / Sulfamethoxazole

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Randomized, Comparative Study of Daily Dapsone and Daily Atovaquone for Prophylaxis Against PCP in HIV-Infected Patients Who Are Intolerant of Trimethoprim and/or Sulfonamides

HIV Infections | Pneumonia, Pneumocystis Carinii

United States, Tanzania
SunWay Biotech Co., LTD.

Not yet recruiting

Effect of ANKASCIN 568-P Products Regulating Blood Lipid

Hyperlipidemias
SunWay Biotech Co., LTD.

Not yet recruiting

Effect of ANKASCIN 568-P Products on Decreasing HbA1c and Regulating Blood Glucose

Metabolic Syndrome | High Blood Sugar
National Medical Research Center for Therapy and...

Completed

Endovenous Laser Ablation in Acute Thrombophlebitis of the Varicose Great Saphenous Vein

Endovenous Laser Ablation | Superficial Vein Thrombosis

Russian Federation
Emory University
National Cancer Institute (NCI)

Recruiting

Repurposing Atovaquone for the Treatment of Platinum-Resistant Ovarian Cancer

Ovarian High Grade Serous Adenocarcinoma | Platinum-Resistant Ovarian Carcinoma

United States
National Institute of Allergy and Infectious Diseases...
Glaxo Wellcome

Completed

A Randomized, Double-Blind Study of 566C80 Versus Septra (Sulfamethoxazole/Trimethoprim) for the Treatment of Pneumocystis Carinii Pneumonia in AIDS Patients

HIV Infections | Pneumonia, Pneumocystis Carinii

United States, Puerto Rico, Canada, France, Belgium, Germany, Netherlands, United Kingdom
Baylor College of Medicine
William Marsh Rice University

Active, not recruiting

Atovaquone (Mepron®) Combined With Conventional Chemotherapy for de Novo Acute Myeloid Leukemia (AML) (ATACC AML)

Acute Myeloid Leukemia

United States
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

A Study to Compare Different Drugs Used to Prevent Serious Bacterial Infections in HIV-Positive Children

HIV Infections | Bacterial Infections | Pneumonia, Pneumocystis Carinii

United States, Puerto Rico

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