Search clinical trials for: BIBW 2992 high dose 6 day

Total 100 results

Boehringer Ingelheim

Completed

BIBW 2992 (Afatinib) in Combination With Pemetrexed in Advanced Solid Tumours

Neoplasms

Canada
Boehringer Ingelheim

Completed

LUX-Lung 4: BIBW 2992 (Afatinib) Phase I Trial in Advanced Non Small Cell Lung Cancer Patients & Phase II Trial in Non Small Cell Lung Cancer Patients Failing Erlotinib or Gefitinib

Carcinoma, Non-Small-Cell Lung

Japan
Boehringer Ingelheim

Completed

Safety, Tolerability and Pharmacokinetics of BIBW 2948 BS for HandiHaler® in Healthy Male Volunteers

Healthy
Boehringer Ingelheim

Completed

Effect of Single Oral Dose BIRB 796 BS on Endotoxin-induced Inflammatory Responses in Healthy Human Subjects

Healthy
Boehringer Ingelheim

Completed

Afatinib and Vinorelbine in Tumours Known to Overexpress EGFR and/or HER2

Neoplasms

France
University of Reading

Unknown

The Vascular and Cognitive Effects of Chronic High-flavanol Intake in Healthy Males

Healthy
Boehringer Ingelheim

Completed

Safety, Tolerability and Pharmacokinetics of Oral BIBP 5371 CL in Healthy Male and Female Volunteers

Healthy
Boehringer Ingelheim

Completed

Safety and Tolerability of 4 Different Dosage Strengths of BIBW 2992 Tablets to Healthy Male Volunteers

Healthy
Jiangsu Province Centers for Disease Control and...
West China Hospital

Completed

Phase I Trial of a Recombinant SARS-CoV-2 Vaccine (Sf9 Cell)

COVID-19

China
Jiangsu Province Centers for Disease Control and...
Academy of Military Medical Sciences，Academy of Military Sciences，PLA; ZHONGYIANKE... and other collaborators

Recruiting

Phase I Trial of a Recombinant COVID-19 Vaccine (CHO Cell)

COVID-19

China
University of South Florida
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Iron Supplementation and Intestinal Health

Very Low Birth Weight Infant | Anemia of Prematurity

United States
Brown University

Completed

Behavioral Economic Analysis of Demand for Marijuana

Marijuana Smoking

United States
Boehringer Ingelheim

Completed

Effect of BIBT 986 Followed by BIBT 986 Given as IV Infusion on Tissue Factor Triggered Coagulation in Healthy Male Volunteers

Healthy
Boehringer Ingelheim

Completed

Safety And Efficacy of BIBF 1120 in Idiopathic Pulmonary Fibrosis

Pulmonary Fibrosis

Argentina, Australia, Belgium, Brazil, Bulgaria, Canada, Chile, China, Czech Republic, France, Germany, Greece, Hungary, Ireland, Italy, Korea, Republic of, Mexico, Netherlands, Portugal, Russian Federation, South Africa, Spain, Taiwan and more
Boehringer Ingelheim

Completed

Efficacy and Safety of Oral Treatment With BIBF 1120 ES in Advanced Non-small-cell Lung Cancer

Carcinoma, Non-Small-Cell Lung
Boehringer Ingelheim

Completed

A Study With BIBF 1120 in Patients With Hormone Refractory Prostate Cancer

Prostatic Neoplasms
Novavax

Completed

RSV-F Vaccine and Influenza Vaccine Co-Administration Study in the Elderly

Respiratory Syncytial Virus (RSV)

United States
Boehringer Ingelheim

Completed

Pharmacodynamics, Preliminary Pharmacokinetics and Tolerability of BIBB 1464 (Tablet) in Hyperlipemic Healthy Male Subjects

Healthy
Boehringer Ingelheim

Completed

Safety, Pharmacokinetics and Pharmacodynamics of BIBR 1048 MS Capsule in Healthy Male Subjects of Japanese and Caucasian Origin

Healthy
Boehringer Ingelheim

Completed

Pharmacokinetics of BIBR 277 in Hypertensive Patients

Hypertension
Receptor Life Sciences

Withdrawn

Safety, Tolerability, and Efficacy of RLS103 in Subjects With Acute Anxiety Within Social Anxiety Disorder (SAD)

Social Anxiety Disorder

United States
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Ontario

Completed

Endothelial Modulation for Angiogenic Therapy

Coronary Artery Disease

Canada
Kilimanjaro Clinical Research Institute
London School of Hygiene and Tropical Medicine; Ifakara Health Institute

Unknown

The Optimal Timing Of Primaquine To Prevent Malaria Transmission After Artemisinin-Combination Therapy

Malaria Transmission

Tanzania
Bayer

Completed

Study to Assess the Safety, Tolerability, Effects on the Body, Absorption, Distribution and Elimination of 25 mg BAY2433334 in Renal Impairment Including Renal Replacement Therapy ("Dialysis")

Prevention of Thromboembolic Events

Germany
Renew Life Formulas Inc
Sprim Advanced Life Sciences

Unknown

Multistrain Probiotic for Functional Constipation

Functional Constipation

United States
Heilpflanzenwohl AG

Completed

BEFORE Study, Efficacy of Refigura

Weight Loss | Overweight and Obesity | Efficacy, Self

Germany
Hiroshima University
Agricultural Producers' Cooperative Corporation Shinpo-en

Completed

Effects of Blueberry Dry Powder on Glycemic Status in Subjects With Prediabetes

Prediabetes

Japan
Dong-A ST Co., Ltd.

Completed

Study to Evaluate the Efficacy and Safety of Intra-articular DA-5202 in Patients With Osteoarthritis of the Knee

Osteoarthritis, Knee

Korea, Republic of
Jiangsu Province Centers for Disease Control and...
Academy of Military Medical Sciences，Academy of Military Sciences，PLA ZHONGYIANKE...

Recruiting

Immunogenicity and Safety of Recombinant COVID-19 Vaccine (CHO Cells)

COVID-19

China
Dong-A ST Co., Ltd.

Completed

Phase II Study of DA-6034 Eye Drops in Dry Eye Syndrome (DES)

Dry Eye Syndrome

Korea, Republic of
Boehringer Ingelheim

Completed

Assessment of Safety, Pharmacokinetics and the Effect of BIBR 1048 MS on Coagulation Parameters in Healthy Volunteer Subjects

Healthy
The Netherlands Cancer Institute
Roche Pharma AG; Borstkanker Onderzoek Groep

Active, not recruiting

Neoadjuvant Chemotherapy in HER2 Positive Breast Cancer, TRAIN-2 (TRAIN-2)

Breast Cancer | HER2 Positive

Netherlands
Fondazione IRCCS San Gerardo dei Tintori
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico; A.O. Ospedale Papa... and other collaborators

Recruiting

Mesenchymal Stromal Cells for Traumatic Brain Injury (MATRIx)

Traumatic Brain Injury With Loss of Consciousness

Italy
Retrotope, Inc.

Completed

A First in Human Study of RT001 in Patients With Friedreich's Ataxia

Friedreich's Ataxia

United States
Louis-Nicolas Veilleux Ph.D.

Completed

Effect of High-Dose Vitamin D on Bone Density in Osteogenesis Imperfecta

Osteogenesis Imperfecta

Canada
Galera Therapeutics, Inc.

Completed

A Study of the Effects of GC4419 on Radiation Induced Oral Mucositis in Patients With Head/Neck Cancer

Radiation Induced Oral Mucositis

United States, Canada, Puerto Rico
Auro Vaccines LLC
United States Department of Defense; Accelovance

Completed

Trial to Evaluate Safety and Immunogenicity of an Ebola Zaire Vaccine in Healthy Adults

Ebola Virus Disease

United States
Memorial Sloan Kettering Cancer Center
GlaxoSmithKline

Completed

Sequential Chemo-Radioimmunotherapy Followed by Autologous Transplantation for Patients With Untreated Advanced Stage Mantle Cell Lymphoma

Mantle Cell Lymphoma

United States
Alan Barkun
Pendopharm

Completed

The Bowel CLEAnsing: A National Initiative (B-CLEAN)

Subjets Requiring a Colonoscopy

Canada
Medical University of Vienna

Completed

The Role of the P2Y12 Receptor in Tissue Factor Induced Coagulation

Sepsis | Healthy Volunteers

Austria
Beijing Tiantan Hospital
NeuroDawn Pharmaceutical Co., Ltd.

Not yet recruiting

EFfects of Y-6 SUblingual Tablets foR PaTients With AcUte Ischemic StRokE (FUTURE)

Acute Ischemic Stroke | Large Vessel Occlusion | Reperfusion
Sinovac Life Sciences Co., Ltd.

Completed

Safety and Immunogenicity Study of Inactivated Vaccine for Prevention of SARS-CoV-2 Infection(COVID-19)

COVID-19

China
Italian Sarcoma Group
French Sarcoma Group; Grupo Espanol de Investigacion en Sarcomas

Active, not recruiting

Localized High-Risk Soft Tissue Sarcomas Of The Extremities And Trunk Wall In Adults: An Integrating Approach Comprising Standard Vs Histotype-Tailored Neoadjuvant Chemotherapy

Localized High-risk Soft Tissue Sarcomas of the Extremities and Trunk Wall in Adults

Spain, Italy
Sidney Kimmel Comprehensive Cancer Center at Johns...
AstraZeneca

Active, not recruiting

CTLA-4 /PD-L1 Blockade Following Transarterial Chemoembolization (DEB-TACE) in Patients With Intermediate Stage of HCC (Hepatocellular Carcinoma) Using Durvalumab and Tremelimumab

Hepatocellular Carcinoma | Intermediate Stage of Hepatocellular Carcinoma

United States
Latin American Cooperative Oncology Group
Merck Sharp & Dohme LLC

Active, not recruiting

Study of a Pembrolizumab-based Organ Preservation Strategy for Locally Advanced Larynx Cancers (SMART-KEY)

Squamous Cell Carcinoma of Larynx

Brazil
Lexicon Pharmaceuticals

Completed

Study of LX4211 in Subjects With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Far Eastern Memorial Hospital
Research Ethics Review Committee

Unknown

Comparing Treatment Efficacy With High and Medium Dose of Fluticasone in Combination With Salmeterol in COPD Patients

Quality of Life | Percentage of Annual Acute Exacerbation

Taiwan
Tanta University

Recruiting

Norepinephrine in Preperiod of Hypotensive Resuscitation in Hemorrhagic Shock

Hemorrhagic Shock | Norepinephrine | Hypotensive Resuscitation

Egypt
Mayo Clinic
National Multiple Sclerosis Society

Terminated

Aspirin for Treatment of Multiple Sclerosis-Related Fatigue

Multiple Sclerosis | Fatigue

United States
National Heart, Lung, and Blood Institute (NHLBI)
Novartis

Recruiting

Eltrombopag With Standard Immunosuppression for Severe Aplastic Anemia

Severe Aplastic Anemia

United States

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