Search clinical trials for: Basiliximab (Simulect)

Total 145 results

Drexel University College of Medicine
Novartis

Terminated

Study to Evaluate the Safety of Chronic Administration of Simulect to Subjects Receiving a First Kidney Transplant (Simulect)

End Stage Renal Disease

United States
Fort Worth Clinical Sciences Working Group
TCU and UNTHSC School of Medicine

Not yet recruiting

Exploratory Regimen of Basiliximab for Treatment of Pulmonary Cytokine Storm in SARS-CoV-2 Hospitalized Adult Patients (FWCSWG-IL-2)

SARS-CoV2 Infection | Cytokine Storm | SARS-CoV-2 Acute Respiratory Disease
Genzyme, a Sanofi Company

Completed

An Open-label, Prospective, Randomized, Multi-center, Phase II Comparative Trial of Thymoglobulin Versus Simulect for the Prevention of Delayed Graft Function and Acute Allograft Rejection in Renal Allograft Recipients.

Cadaveric Donor Renal Transplantation | Acute Renal Allograft Rejection | Induction Therapy

United States, France, Spain, United Kingdom, Germany
Indiana University School of Medicine

Completed

Basiliximab #2: In-Vivo Activated T-Cell Depletion to Prevent Graft-Versus_Host Disease (GVHD) After Nonmyeloablative Allotransplantation for the Treatment of Blood Cancer

Multiple Myeloma | Non-Hodgkin's Lymphoma | Myelofibrosis | Chronic Lymphocytic Leukemia | Anemia, Aplastic | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Myelodysplasia | Hemoglobinuria, Paroxysmal | Hodgkin's Disease

United States
King Faisal Specialist Hospital & Research Center

Recruiting

Standard Induction With Basiliximab Versus No-Induction in Low Immunological Risk Kidney Transplant Recipients

Kidney Transplantation

Saudi Arabia
Cerimon Pharmaceuticals

Completed

Basiliximab in Moderate to Severe Ulcerative Colitis

Ulcerative Colitis

United States, Poland, Belgium, United Kingdom, Czech Republic, Russian Federation, Slovakia, Ukraine, India
Gang Chen
Changhai Hospital; First Affiliated Hospital, Sun Yat-Sen University; The First... and other collaborators

Completed

Pediatric Induction Therapy in Kidney Transplantation (PINK)

Kidney Transplant Rejection | Pediatric Kidney Disease

China
Nationwide Children's Hospital

Terminated

Infliximab and Basiliximab for Treatment of Steroid Refractory Acute Graft Versus Host Disease

Graft Versus Host Disease | Acute GVH Disease | Steroid Refractory GVHD

United States
Coordinación de Investigación en Salud, Mexico

Completed

Basiliximab vs Low-dose Thymoglobulin Induction Therapy in Low Risk Kidney Transplant Patients

Kidney Transplant Rejection | Kidney Transplant; Complications

Mexico
Cerimon Pharmaceuticals
PPD

Terminated

The Safety and Efficacy of Basiliximab as Maintenance Therapy in Subjects With Stable, Noninfectious Uveitis (BSX-003)

Non-infectious Uveitis

United States
Cerimon Pharmaceuticals

Terminated

Basiliximab Maintenance in Ulcerative Colitis

Ulcerative Colitis

United Kingdom
Novartis Pharmaceuticals

Completed

Preservation of Renal Function in Liver Transplant Recipients With Certican Therapy

Liver Transplantation

Germany, Netherlands, Switzerland, Austria
Mario Negri Institute for Pharmacological Research

Not yet recruiting

1 vs 7 RATG Infusions in Renal Transplantation (ONSET)

Kidney Replacement

Italy
Armin Goralczyk

Unknown

Safety Study of Calcineurin-Inhibitor-Free Immunosuppression After Liver Transplantation (CILT)

Liver Transplantation | Chronic Renal Insufficiency

Germany
University of Pennsylvania

Terminated

Effect of Thymoglobulin Versus Basiliximab on Regulatory T Cell Function in Live Donor Kidney Transplant Recipients (TReg Kidney)

KIDNEY TRANSPLANTATION

United States
Centre Hospitalier Universitaire de Saint Etienne

Terminated

Prevention in Recipients With Primary IgA Nephropathy of Recurrence After Kidney Transplantation: ATG-F Versus Basiliximab as Induction Immunosuppressive Treatment (PIRAT)

Glomerulonephritis | IgAN

France
University of Oxford
Genzyme, a Sanofi Company; Oxford University Hospitals NHS Trust

Unknown

Thymoglobulin Induction in Kidney Transplant Recipients (TIKT)

Kidney Transplantation | Ischemia-Reperfusion Injury

United Kingdom
Novartis

Completed

Everolimus in a Cyclosporine Microemulsion-free Regimen Compared to a Low-dose Cyclosporine Microemulsion Regimen, in de Novo Kidney Transplant Patients (CERTES02)

Organ Transplantation, Renal Transplantation
Novartis

Completed

Safety and Efficacy of Basiliximab in Calcineurin Inhibitor Intolerant Long-term Kidney Transplant Recipients Treated With Mycophenolic Acid and Steroids

Kidney Transplantation | Adverse Effects

Switzerland
Asan Medical Center

Unknown

The Usefulness of Tacrolimus Without Basiliximab in Well Matched Living Renal Transplantation in Korea

Kidney Transplantation

Korea, Republic of
McGill University Health Centre/Research Institute...

Unknown

EXTEND Protocol for Transplanted Patient to Evaluate Kidney Function

Kidney Transplant

Canada
University Hospital Freiburg
Roche Pharma AG; Genzyme, a Sanofi Company; Astellas Pharma GmbH

Completed

Phase IV Study to Evaluate Calcineurin Inhibitor Reduced, Steroid Free Immunosuppression After Renal Transplantation (Harmony)

Disorder Related to Renal Transplantation

Germany
Astellas Pharma Inc

Completed

Safety/Efficacy of Induction Agents With Tacrolimus, MMF, and Rapid Steroid Withdrawal in Renal Transplant Recipients (INTAC)

Kidney Transplantation

United States
University Hospital, Toulouse
Novartis; Neovii Biotech

Completed

Simulect Versus ATG in Sensitized Renal Transplant Patient (SATIR)

Renal Transplant Rejection

France
Gary Archer Ph.D.
National Cancer Institute (NCI)

Completed

Basiliximab in Treating Patients With Newly Diagnosed Glioblastoma Multiforme Undergoing Targeted Immunotherapy and Temozolomide-Caused Lymphopenia (REGULATe)

Malignant Neoplasms Brain

United States
Astellas Pharma Inc

Completed

A Study to Assess the Safety and Efficacy of Alefacept in Kidney Transplant Recipients

Kidney Transplantation

United States
The First Affiliated Hospital of Soochow University
The Second People's Hospital of Huai'an; Soochow Hopes Hematonosis Hospital

Recruiting

Basiliximab Combined With Ruxolitinib as Second-line Treatment of Grade 3-4 Steroid-resistant aGVHD

Safety and Efficacy

China
University Health Network, Toronto
Novartis

Completed

Study Comparing Simulect Plus Standard Immunosuppression to Standard Immunosuppression Alone for the Prevention of Acute Rejection and Bronchiolitis Obliterans in Lung Transplant

Emphysema | COPD | Alpha-1 Antitrypsan Deficiency

Canada
Novartis Pharmaceuticals

Completed

Progression of Renal Interstitial Fibrosis / Tubular Atrophy (IF/TA) According to Epithelial-mesenchymal Transition (EMT) and Immunosuppressive Regimen (Everolimus Based Versus CNI Based) in de Novo Renal Transplant Recipients (CERTITEM)

Renal Interstitial Fibrosis

France
Fuzhou General Hospital

Unknown

Induction With SVF Derived MSC in Living-related Kidney Transplantation

Living-relative Kidney Transplantation

China
University Hospital, Brest

Unknown

Influence of Thymoglobuline on Phenotypic and Functional Profiles of B Lymphocytes in Renal Transplant Recipients (THYMO B)

Renal Transplant

France
Luye Pharma Group Ltd.

Completed

A Dose-escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetic of LPM3770164 in Healthy Subjects

Tardive Dyskinesia | Huntington Disease

China
Nantes University Hospital

Terminated

ATG Versus Basiliximab in Kidney Transplant Displaying Low Immunological Risk But High Susceptibility to DGF (PREDICT-DGF)

Kidney Transplantation

France
Vastra Gotaland Region

Completed

Trial of Steroid Avoidance and Low-dose CNI by ATG-induction in Renal Transplantation (SAILOR)

Diabetes Mellitus

Sweden
Novartis Pharmaceuticals

Completed

Advancing Renal TRANSplant eFficacy and Safety Outcomes With an eveRolimus-based regiMen (TRANSFORM) (TRANSFORM)

Hemodialysis | Renal Replacement Therapy | End Stage Renal Disease (ESRD) | Renal Transplantation | Chronic Kidney Disease (CKD)

Germany, United States, Belgium, Italy, Spain, Croatia, Taiwan, Australia, Austria, Greece, Korea, Republic of, Lebanon, Czechia, Israel, Netherlands, Slovenia, Switzerland, Thailand, Norway, Turkey, Sweden, Argentina, Brazil, Japan, Se... and more
University of Chicago

Active, not recruiting

Stem Cell Transplantation for Patients With Multiple Myeloma

Myeloma

United States
Novartis Pharmaceuticals

Completed

A National Multi-center Randomized, Open Label Study to Evaluate Efficacy and Safety of Everolimus With EC-MPS Compared to Standard Treatment Combination Tacrolimus and EC-MPS in de Novo Liver Transplant Recipients (SIMCER)

Liver Transplantation

France
Novartis

Completed

Efficacy and Safety of Basiliximab, Cyclosporine/Cyclosporine Microemulsion, and Steroids in Pediatric de Novo Liver Transplant Recipients Avoiding Intraoperative Steroids

Liver Transplantation | Infection

Germany
University of Chicago
National Cancer Institute (NCI)

Completed

Vaccine Therapy and Basiliximab in Treating Patients With Acute Myeloid Leukemia in Complete Remission

Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8;21)(q22;q22) | Adult Acute Myeloid Leukemia... and other conditions

United States
Affiliated hospital of guangxi medical university...
Zhongshan Hospital Xiamen University; The Affiliated Nanjing Drum Tower Hospital... and other collaborators

Unknown

Efficacy of Basiliximab in the Prevention of Acute Graft-versus-host Disease in Unrelated Allogeneic Hematopoietic Stem Cell Transplantation Therapy for Thalassemia Major

Beta-Thalassemia Major

China
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Radiolabeled Monoclonal Antibody Therapy and Combination Chemotherapy Before Stem Cell Transplant in Treating Patients With Primary Refractory or Relapsed Hodgkin Lymphoma

Recurrent Adult Hodgkin Lymphoma

United States
University of Oxford
Novartis; Pfizer; National Health Service, United Kingdom

Completed

Campath, Calcineurin Inhibitor Reduction and Chronic Allograft Nephropathy (3C)

Kidney Transplantation

United Kingdom
Hospital Authority, Hong Kong
Novartis Pharmaceuticals; The Hong Kong Blood Cancer Foundation

Unknown

Basiliximab for the Treatment of Acute Graft-versus-host Disease After Allogeneic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation | Graft vs Host Disease

China
Armando Torres Ramírez

Terminated

Optimum Immunosuppression in Renal Transplant Recipients.New Onset Diabetes After Transplantation (01-DMPT)

Diabetes Mellitus, Adult-Onset

Spain
Xiyuan Hospital of China Academy of Chinese Medical...
The First Affiliated Hospital of Henan University of Traditional Chinese... and other collaborators

Recruiting

Efficacy and Safety of WPQW Granule for Overlap of NERD and IBS-D

Non-erosive Reflux Disease | Diarrhea-Predominant Irritable Bowel Syndrome

China
Xiyuan Hospital of China Academy of Chinese Medical...
First Affiliated Hospital of Heilongjiang Chinese Medicine University; Liuzhou... and other collaborators

Recruiting

Assessment on Effects of Tongjiang Granule in Treating Nonerosive Reflux Disease Overlapping Epigastric Pain Syndrome

Gastroesophageal Reflux | Functional Dysphonia

China
Jiangxi Qingfeng Pharmaceutical Co. Ltd.

Completed

A Clinical Study on the Safety and Efficacy of GP681 Tablets in the Treatment of Uncomplicated Acute Influenza

Influenza

China
University of California, Los Angeles
Novartis

Completed

Safety and Efficacy of Basiliximab, Delayed Dose Tacrolimus Plus ECMPA (Enteric Coated Mycophenolic Acid) Following Liver Transplantation

Liver Transplantation

United States
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

A Randomized, Double-Blind, Dose-Escalation, Placebo-Controlled Phase I Clinical Trial Investigating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Oral Doses of HRS-7085 Tablets in Healthy Subjects, With Assessment of Food Effects

Inflammatory Bowel Disease
Astellas Pharma Global Development, Inc.
Kyowa Kirin Co., Ltd.

Completed

A Study to Assess the Efficacy and Safety of ASKP1240 in de Novo Kidney Transplant Recipients

Kidney Transplantation

United States

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