Search clinical trials for: Bosentan 62.5 mg

Total 10596 results

Actelion

Completed

Bosentan in Digital Ulcers (RAPIDS 2 OL)

Digital Ulcers

France, United Kingdom, United States, Austria, Canada, Germany, Italy, Switzerland
Actelion

Completed

Efficacy and Safety of Oral Bosentan on Healing/Prevention of Digital (Finger) Ulcers in Patients With Scleroderma (RAPIDS-2)

Systemic Sclerosis | Digital Ulcers

United States, Canada
Hanmi Pharmaceutical Company Limited

Completed

To Compare the Pharmacokinetics of Traclear 62.5 mg Tablets and HGP1206 125mg 1 Tablet in Healthy Male Volunteers

Pulmonary Arterial Hypertension

Korea, Republic of
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Aliskiren in Pediatric Hypertensive Patients 6-17 Years of Age

Hypertension

United States, Belgium, Hungary, Turkey, Guatemala, Slovakia, Germany, Puerto Rico, Poland
University of Missouri-Columbia
Mayo Clinic; National Heart, Lung, and Blood Institute (NHLBI)

Completed

Reflex Responses to Intermittent Hypoxia in Humans: Mechanisms and Consequences

Healthy | Sleep Apnea | Vasodilation | Vasoconstriction

United States
Geropharm

Completed

Bioequivalence Study of Bosentan 125 mg Tablets Immediate Release (IR) Versus Tracleer® 125 mg Tablets IR In Healthy Subjects

Bioequivalence

Russian Federation
Assistance Publique - Hôpitaux de Paris

Completed

Effects of Bosentan (Tracleer) in the Course of Pulmonary Artery Hypertension Induced by Hypoxia

Hypoxia-Induced Pulmonary Artery Hypertension

France
Grünenthal GmbH

Completed

Efficacy and Safety of Intravenous Neridronic Acid in CRPS-I

Complex Regional Pain Syndrome, Type I

United States, Germany, United Kingdom
CSPC Baike (Shandong) Biopharmaceutical Co., Ltd.

Not yet recruiting

A Study of TG103 Injection in the Management of Non-diabetic Overweight or Obesity

Obesity | Overweight
Novartis Pharmaceuticals

Completed

A Study to Assess the Safety and Efficacy of Eltrombopag in Japanese Subjects With Refractory, Moderate or More Severe Aplastic Anemia

Cytopaenia

Japan
NYU Langone Health

Completed

A Randomized Placebo-controlled Safety and Dose-finding Study for the Use of the IL-6 Inhibitor Clazakizumab in Patients With Life-threatening COVID-19 Infection

COVID-19

United States
CSPC Baike (Shandong) Biopharmaceutical Co., Ltd.

Recruiting

A Study of TG103 Injection in Overweight or Obesity

Overweight or Obesity

China
CSPC Baike (Shandong) Biopharmaceutical Co., Ltd.

Not yet recruiting

A Study of TG103 Injection in Non-diabetic Overweight or Obesity

Overweight or Obesity

China
AstraZeneca

Completed

A Phase IIa. Open-label, Multicenter, Dose-escalation Study to Assess the Tolerability and Pharmacokinetics of ZD4054 (Zibotentan) Given Orally Once Daily in Subjects With Metastatic Prostate Cancer

Prostatic Neoplasms | Metastases, Neoplasm

United States
Idorsia Pharmaceuticals Ltd.
Janssen Biotech, Inc.

Completed

A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and Find Out More About Its Safety (PRECISION)

Resistant Hypertension

Spain, Israel, Czechia, United States, Canada, China, Hungary, Netherlands, Poland, United Kingdom, Germany, Australia, Belgium, Finland, France, Greece, Italy, Lithuania, Russian Federation, Ukraine
GlaxoSmithKline

Completed

A New Oral Treatment For Type II Diabetes Mellitus

Diabetes Mellitus, Type 2

United States, Germany, Canada, Sweden, Latvia, Finland, Greece, Romania, Czechia, Puerto Rico
Eisai Inc.

Completed

A Two-Part Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2006 in Healthy Japanese and White Subjects

Healthy Volunteers

United States
Edgewise Therapeutics, Inc.
Medpace, Inc.; SYSNAV; ImagingNMD

Recruiting

Phase 2 Study of EDG-5506 in Becker Muscular Dystrophy (GRAND CANYON)

Becker Muscular Dystrophy

United States, Netherlands, United Kingdom
Nymox Corporation

Completed

Two-Dose Level Evaluation of NX-1207 for the Treatment of Low Risk, Localized (T1c) Prostate Cancer

Prostate Cancer

United States
Actelion

Completed

Bosentan in Patients With Inoperable Chronic Thromboembolic Pulmonary Hypertension (CTEPH) (BENEFIT OL)

Pulmonary Hypertension

United States, Canada, Australia, Germany, Italy, United Kingdom, France, Austria, Belgium, Czech Republic, Netherlands, Poland, Spain
Medical University of Vienna

Completed

Effects of Non-Specific Endothelin-A Receptor Blockade on Ocular Blood Flow in Patients With Glaucoma

Glaucoma | Blood Flow Velocity

Austria
Actelion

Completed

Effects of Tracleer (Bosentan) on Pulmonary Arterial Hypertension Related to Eisenmenger Physiology

Pulmonary Arterial Hypertension Related to Eisenmenger Physiology

Canada, United Kingdom, Italy, United States, Netherlands, Australia, Austria, Belgium, France, Germany, Spain
Boehringer Ingelheim
Eli Lilly and Company

Completed

Bioavailability of Empagliflozin/Metformin Fixed Dose Combinations (FDCs) in Healthy Chinese Volunteers

Healthy

China
Kyowa Kirin Co., Ltd.

Completed

A Study of OPC-262 in Patients With Type 2 Diabetes

Diabetes Type 2

Japan
Minerva Neurosciences

Completed

A Study to Evaluate the Efficacy and Safety of MIN-117 in Adult Patients With Major Depressive Disorder

Major Depressive Disorder

United States, Bulgaria, Finland, Georgia, Moldova, Republic of, Poland, Ukraine
Actelion

Completed

Open-label Study With Bosentan in Interstitial Lung Disease (BUILD 2 OL)

Interstitial Lung Disease | Scleroderma

United States, Korea, Republic of, Israel, France, United Kingdom, Netherlands, Switzerland, Germany, Canada, Italy, Sweden
General Hospital of Chalkida

Unknown

Bosentan for Severe Mitral Valve Dysfunction (BOSMIVAR)

SECONDARY PULMONARY HYPERTENSION | MITRAL STENOSIS | CHILDHOOD RHEUMATOID FEVER | CONGESTIVE HEART FAILURE

Greece
Rikshospitalet University Hospital

Terminated

Treatment of Early Systemic Sclerosis by Bosentan (TRANOS)

Systemic Sclerosis (Scleroderma)

Norway
Notal Vision Ltd.
Elman Retina Group

Completed

NOTAL-OCT V.2.5 vs Commercial OCT in AMD Patients

Diabetic Macular Edema | AMD - Age-Related Macular Degeneration

United States
PharmaMar
Apices Soluciones S.L.

Completed

Extension Study in a Cohort of Adult Patients With COVID-19 Infection (E-APLICOV-PC)

COVID-19 Infection

Spain
RemeGen Co., Ltd.

Recruiting

A Study of Telitacicept in Subjects With Childhood-onset Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

China
University Hospital, Grenoble

Recruiting

ENDOTHELION Study Group: Effect of Bosentan in NAION Patients (ENDOTHELION)

Ischemic Optic Neuropathy

France
Daniel Doberer

Terminated

Safety and Efficacy Study of Bosentan in Progressive Pulmonary Sarcoidosis (BOPSAC)

Pulmonary Hypertension | Sarcoidosis

Austria
Actelion

Terminated

Efficacy and Safety of Bosentan in Sickle Cell Disease (SCD) Patients Diagnosed With Pulmonary Hypertension (PH) (ASSET-2)

Pulmonary Hypertension

United States, France, United Kingdom, Netherlands
Hamilton Health Sciences Corporation
Actelion

Unknown

A Study to Evaluate the Use of Bosentan in Patients With Exercise Induced Pulmonary Arterial Hypertension Associated With Connective Tissue Disease

Hypertension, Pulmonary | Connective Tissue Disease

Canada
Bayer
Merck Sharp & Dohme LLC; Duke Clinical Research Institute; Canadian VIGOUR Centre

Completed

Patient-reported Outcomes in Vericiguat-treated Patients With HFpEF (VITALITY-HFpEF)

Chronic Heart Failure With Preserved Ejection Fraction

Spain, United States, Belgium, Singapore, Taiwan, Canada, Japan, Italy, Austria, Bulgaria, Germany, Greece, Israel, Poland, Portugal, Hungary, Russian Federation, Argentina, Colombia, Malaysia, South Africa
Rajan Saggar
Actelion

Withdrawn

Pulmonary Arterial Hypertension Secondary to Idiopathic Pulmonary Fibrosis and Treatment With Bosentan

Idiopathic Pulmonary Fibrosis | Pulmonary Arterial Hypertension

United States
Actelion

Completed

Pulmonary Artery Remodelling With Bosentan

Hypertension, Pulmonary

Australia
UConn Health
Actelion

Terminated

Bosentan for Poorly Controlled Asthma

Asthma

United States
VA Loma Linda Health Care System
Actelion

Completed

Effect of Bosentan on Exercise Capacity at High Altitude

Pulmonary Hypertension | Altitude

United States
Guangdong Zhongsheng Pharmaceutical Co., Ltd.

Completed

Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single Ascending Dose of ZSP1603 in Healthy Adults

Solid Tumor | Idiopathic Pulmonary Fibrosis(IPF)

China
George Medicines PTY Limited

Completed

Efficacy and Safety of GMRx2 Compared to Dual Combinations for the Treatment of Hypertension (GMRx2_ACT)

Hypertension

Australia, United States, United Kingdom, Poland, Sri Lanka, New Zealand, Czechia
Elpen Pharmaceutical Co. Inc.

Completed

Bosentan Treatment of Digital Ulcers Related to Systemic Sclerosis (GRegistry SCDU)

Scleroderma | Digital Ulcer | Systematic Sclerosis

Greece
University Medical Center Groningen
Actelion

Completed

The Clinical And Subclinical Effects on Arterial Stiffness of Bosentan in Patients With Systemic Sclerosis (CEASESTIFF)

Scleroderma, Systemic

Netherlands
Berto J Bouma

Unknown

Bosentan Improves Clinical Outcome of Adults With Congenital Heart Disease or Mitral Valve Lesions Who Undergo CArdiac Surgery (BOCA)

Congenital Heart Disease

Netherlands
Actelion

Completed

Bosentan Effects in Inoperable Forms of Chronic Thromboembolic Pulmonary Hypertension

Chronic Thromboembolic Pulmonary Hypertension

Canada, Australia, Germany, United States, Italy, United Kingdom, Austria, Belgium, Czech Republic, France, Netherlands, Poland, Spain
Heinrich-Heine University, Duesseldorf

Completed

Effect of Bosentan on Skin Fibrosis in Patients With Systemic Sclerosis

Systemic Scleroderma | Skin Fibrosis | Hand Functionality

Germany
MedImmune LLC

Completed

Safety/Efficacy of MEDI-551 in Combination With Immunomodulating Therapies in Subjects With Aggressive B-cell Lymphomas

Relapsed/Refractory Aggressive B-cell Lymphomas

United States
Eisai Co., Ltd.

Completed

A Randomized, Double-blind, Placebo-controlled Study to Assess Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamic Response of Repeated Intravenous Infusions of BAN2401 in Subjects With Mild Cognitive Impairment Due to Alzheimer's Disease and Mild Alzheimer's Disease

Alzheimer's Disease

Japan
Actelion

Completed

The Effect of Tracleer® on Male Fertility

Hypertension, Pulmonary

United States, Australia, Brazil, Czech Republic, Hungary

Search clinical trials for: Bosentan 62.5 mg

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