Search clinical trials for: CHR-2797

Total 2473 results

Chroma Therapeutics

Completed

Safety and Anti-Disease Activity of CHR-2797 (Tosedostat) in Elderly and/or Treatment Refractory Patients With Acute Myeloid Leukemia (AML) and Multiple Myeloma (MM)

Acute Myeloid Leukemia | Multiple Myeloma | Myelodysplastic Syndrome

United Kingdom
Weill Medical College of Cornell University
CTI BioPharma

Completed

Study of Clinical Efficacy and Safety of Tosedostat in MDS (IST-CTI-MDS)

Myelodysplastic Syndrome

United States
Chroma Therapeutics
Institute of Cancer Research, United Kingdom

Completed

Safety Study to Evaluate CHR-2797 in Patients With Advanced Tumours

Advanced Solid Tumors
Chroma Therapeutics

Unknown

Extension Study With Tosedostat in Relapsed/Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia

United States
Chroma Therapeutics
Quintiles, Inc.

Completed

Safety and Anti-Disease Activity of Oral Tosedostat (CHR-2797) in Elderly Subjects With Refractory or Relapsed AML (OPAL)

Acute Myeloid Leukemia | AML

United States, Canada, Netherlands
Chroma Therapeutics

Completed

A Study of the Safety and Tolerability of the Addition of CHR-2797 to Paclitaxel in Patients With Advanced or Refractory Tumours

Solid Tumor

Netherlands
CTI BioPharma
Chroma Therapeutics

Completed

Crossover Trial of the Effect of a High-Fat Meal on the PK of Oral CHR 2797 in Healthy Male Subjects (8265134)

Healthy

United States
Chroma Therapeutics

Terminated

Clinical Trial of the Safety and Effectiveness of CHR-2797 With Erlotinib in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Tosedostat in Combination With Cytarabine or Decitabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Secondary Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia | Previously Treated Myelodysplastic Syndromes | Secondary Myelodysplastic Syndromes | Adult Acute Myeloid Leukemia... and other conditions

United States
Dr. August Wolff GmbH & Co. KG Arzneimittel
proDERM GmbH

Completed

Investigation of Efficacy and Tolerability of WO 2707, a MoistCream Cremolum, in Postmenopausal Women Suffering From Symptoms of Vaginal Dryness

Vaginal Atrophy

Germany
Brii Biosciences Limited

Completed

A Study of BRII-297 in Healthy Adult Subjects

Postpartum Depression

Australia
OSE Immunotherapeutics

Recruiting

Dose-finding and Dose Expansion Study of OSE-279 in Subjects With Advanced Solid Tumors or Lymphomas

Lymphoma | Solid Advanced Tumor

France, Belgium
Kinnate Biopharma

Recruiting

A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors

Melanoma | Non-small Cell Lung Cancer | Solid Tumor, Adult

United States, Australia, France, Spain, Taiwan, Korea, Republic of, China, Netherlands
NYU Langone Health
National Institute on Minority Health and Health Disparities (NIMHD)

Completed

Patient-Centered Cancer Prevention In Chinese Americans

H. Pylori Infection

United States
Takeda

Recruiting

A Study of TAK-279 in Adult Participants With Generalized Pustular Psoriasis or Erythrodermic Psoriasis

Generalized Pustular Psoriasis | Erythrodermic Psoriasis

Japan
PATH
GlaxoSmithKline; Icahn School of Medicine at Mount Sinai; Duke University; Children... and other collaborators

Completed

Safety and Immunogenicity of a Live-attenuated Universal Flu Vaccine Followed by an Inactivated Universal Flu Vaccine

Influenza | Vaccine

United States
Takeda

Not yet recruiting

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis
Takeda

Recruiting

A Study of TAK-279 in Adults With or Without Kidney Problems

Renal Impairment | Healthy Volunteers

United States
MiNK Therapeutics

Completed

Evaluate the Safety of agenT-797 in Participants With Moderate to Severe Difficulty Breathing Secondary to SARS-CoV-2

Respiratory Distress Syndrome, Adult

United States
Takeda

Recruiting

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

Crohn's Disease

United States
Takeda

Not yet recruiting

A Study of TAK-279 in Healthy Chinese Adults

Healthy Volunteers

China
Takeda
Nimbus Lakshmi, Inc.

Completed

A Study to Evaluate the Efficacy, Safety, and Tolerability of NDI-034858 in Participants With Active Psoriatic Arthritis

Psoriatic Arthritis

United States, Czechia, Germany, Poland
GlaxoSmithKline

Completed

A Study to Evaluate the Reactogenicity, Safety and Immunogenicity of GlaxoSmithKline (GSK) Biologicals' Investigational Supra-seasonal Universal Influenza Vaccines - Inactivated (SUIVs) (GSK3816302A) in Healthy Adults Aged 18 to 39 Years

Influenza, Human

United States, Belgium
Chimeric Therapeutics

Not yet recruiting

A Phase 1/2 Study to Evaluate CHM-2101, an Autologous Cadherin 17 Chimeric Antigen Receptor (CAR) T Cell Therapy

Gastric Cancer | Colorectal Cancer | Neuroendocrine Tumors
Chimeric Therapeutics

Recruiting

CAR T Cells in Patients With MMP2+ Recurrent or Progressive Glioblastoma

Glioblastoma Multiforme of Brain

United States
Egyptian Biomedical Research Network

Completed

Intravenous Dexmedetomidine in Cesarean Section Under Spinal Anesthesia

Cesarean Section Complications

Egypt
GlaxoSmithKline

Terminated

Phase 1 Dose Escalating Study to Assess Safety, Tolerability, Food Effect and PK of CHR-5154 in Healthy Male Volunteers

Arthritis, Rheumatoid

United Kingdom
Ribon Therapeutics, Inc.

Recruiting

Phase 1 Study of RBN-2397, an Oral PARP7 Inhibitor, in Patients With Solid Tumors

Solid Tumor, Adult

United States, Spain
Takeda

Recruiting

A Study of TAK-279 in Adults With or Without Liver Damage

Healthy Volunteers | Hepatic Impairment

United States
Chong Kun Dang Pharmaceutical

Completed

A Clinical Study to Evaluate the Pharmacokinetics, Safety and Tolerability of CKD-355

Alzheimer's Disease (AD)

Korea, Republic of
MiNK Therapeutics

Completed

agenT-797 in Participants With Relapsed/Refractory Multiple Myeloma

Relapsed/Refractory Multiple Myeloma

United States
Enanta Pharmaceuticals, Inc
PRA Health Sciences

Completed

A Study of EDP-297 in Healthy Subjects

NASH - Nonalcoholic Steatohepatitis With Liver Fibrosis

Netherlands
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Tosedostat and Cytarabine or Azacitidine in Treating Older Participants With Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome

Acute Myeloid Leukemia | High Risk Myelodysplastic Syndrome

United States
Boehringer Ingelheim

Completed

Pharmacokinetics of BIBR 277 in Hypertensive Patients

Hypertension
Ruhr University of Bochum

Completed

Tachosil for the Prevention of Symptomatic Lymph Cysts

Cervical Cancer | Endometrial Cancer

Austria, Germany
Chroma Therapeutics

Completed

Safety and Tolerability of CHR-2845 to Treat Haematological Diseases or Lymphoid Malignancies (CHR-2845-001)

Lymphoid Malignancies | Hematological Disease

France, Belgium, Netherlands
University of California, Irvine
University of Maryland, Baltimore County

Not yet recruiting

Youth Nominated Support Team (YST)

Suicide | Psychosis | Health Care Utilization | Family Members
Boehringer Ingelheim

Completed

Bioequivalence of BIBR 277 Tablet Compared With Capsule in Healthy Male Volunteers

Healthy
MiNK Therapeutics

Completed

A Study Investigating agenT-797 in Participants With Relapsed/Refractory Solid Tumors

Tumor, Solid

United States
Fudan University

Recruiting

A Clinical Trial of Breast Cancer Neo-adjuvant Therapy Based on Molecular Pathway in FUSCC

Breast Cancer

China
Invicro

Recruiting

Proof of Mechanism Study to Evaluate Binding of Alfa-synuclein

Parkinson Disease | Healthy Volunteer | Multisystem Atrophy

United States
Peloton Therapeutics, Inc.

Active, not recruiting

A Trial of Belzutifan (PT2977, MK-6482) Tablets In Patients With Advanced Solid Tumors (MK-6482-001)

Kidney Cancer | Clear Cell Renal Cell Carcinoma | Glioblastoma | Solid Tumor | Glioblastoma Multiforme | Advanced Solid Tumors | GBM | Solid Tumor, Adult | Solid Carcinoma | Glioblastoma, Adult | ccRCC | RCC, Clear Cell Adenocarcinoma | RCC | Renal Cell Carcinoma, Metastatic | Renal Cell Carcinoma Recurrent | Renal Cell...
Takeda
Nimbus Lakshmi, Inc.; Innovaderm Research Inc.

Completed

Study of NDI-034858 in Participants With Moderate to Severe Plaque Psoriasis

Moderate to Severe Plaque Psoriasis

United States, Canada
Shenyang Sunshine Pharmaceutical Co., LTD.

Unknown

rESP Medication With a Single Intravenous Administration and Dose Escalation to Explore the Tolerability ,Safety and Pharmacokinetic Characteristics

Chronic Renal Failure

China
Karolinska Institutet
Swedish Heart Lung Foundation

Completed

Compression Only-CPR Versus Standard-CPR (TANGO2)

Cardiac Arrest | Out of Hospital Cardiac Arrest

Sweden
Rhode Island Hospital

Recruiting

A Treatment Engagement Protocol for Psychiatrically Hospitalized Adolescents at Clinical High Risk for Psychosis

Psychosis Nos/Other

United States
Boehringer Ingelheim

Completed

Bioequivalence of BIBR 277 Tablet (Mannitol Based) Compared With Capsule Formulation in Healthy Male Volunteers

Healthy
Chiesi Farmaceutici S.p.A.
SGS S.A.

Completed

Pharmacodynamics, Pharmacokinetics and Safety of Two Doses of CHF6001 DPI in Subjects With Moderate, Severe COPD

COPD

United Kingdom
Per Bendix Jeppesen
Future Food Innovation

Completed

The Effect of a Vegan Alginate Product on Athletes Recovery and Performance

Athletic Performance

Denmark
Universiti Putra Malaysia

Recruiting

Effect of Latin Dance on Middle School Girls' Social Physique Anxiety and Physical Self-esteem

Mental Health Issue | Physical Illness

China

Search clinical trials for: CHR-2797

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