Search clinical trials for: CK-0045

Total 302 results

Cytoki Pharma
SGS Life Sciences, a division of SGS Belgium NV

Completed

A Phase 1 Study to Investigate Safety, Tolerability, and Pharmacokinetics of CK-0045 in Healthy Participants and Otherwise Healthy Participants With Obesity

Healthy

Belgium
Cytokinetics

Recruiting

A Single and Multiple Ascending Dose Study of CK-4021586 in Healthy Adult Participants

Healthy Participants

United States
Cytokinetics

Recruiting

A Single and Multiple Ascending Dose Study of CK-3828136 in Healthy Adult Participants

Healthy Participants

United States
Cytokinetics

Completed

A Study of CK-2017357 in Patients With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

United States
Oregon Social Learning Center
Office of Planning, Research & Evaluation

Recruiting

KEEP Connecting Kin (KEEP-CK)

Parenting | Externalizing Behavior | Parent Stress | Internalizing Behavior | Child Permanency | Service Utilization

United States
Cytokinetics

Completed

A Single and Multiple Ascending Dose Study of CK-3773274 in Healthy Adult Subjects

Healthy Subjects | Symptomatic Obstructive Hypertrophic Cardiomyopathy

United States
Cytokinetics

Completed

PK and Tolerability of IV and Oral CK-1827452 in Patients With Ischemic Cardiomyopathy and Angina

Myocardial Ischemia | Heart Failure | Angina Pectoris

Georgia, Russian Federation
Cytokinetics

Completed

A Study for Patients Who Completed VITALITY-ALS (CY 4031) (VIGOR-ALS)

Amyotrophic Lateral Sclerosis (ALS)

United States, Netherlands, Canada, Belgium, United Kingdom, France, Germany, Ireland, Italy, Portugal, Spain
Cytokinetics

Completed

A Study of CK-2017357 in Patients With Peripheral Artery Disease and Symptomatic Claudication

Intermittent Claudication | Peripheral Artery Disease

United States
Cytokinetics

Completed

Dose-finding Study to Evaluate the Safety, Tolerability, PK, and PD of CK-3773274 in Adults With HCM (REDWOOD-HCM)

Hypertrophic Cardiomyopathy (HCM)

United States, Spain, Italy, Netherlands
Checkpoint Therapeutics, Inc.
Novotech (Australia) Pty Limited

Recruiting

Phase 1 Study of CK-301 (Cosibelimab) as a Single Agent in Subjects With Advanced Cancers

Melanoma | Renal Cell Carcinoma | Head and Neck Cancer | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms | Non Hodgkin Lymphoma | Endometrial Cancer | Carcinoma, Small Cell | Urothelial Carcinoma | Classical Hodgkin Lymphoma | Merkel Cell Carcinoma | Cutaneous Squamous Cell Carcinoma | Malignant Mesothelioma, Advanced

Australia, New Zealand, Thailand, Ukraine, Spain, Russian Federation, France, Poland, South Africa
Cytokinetics

Completed

A Study of CK-1827452 Infusion in Stable Heart Failure

Heart Failure

United States, United Kingdom, Georgia, Russian Federation
University of Aarhus
TRYG Foundation

Unknown

Cognitive Behavioral Therapy for Adolescents With Social Anxiety Disorder

Social Anxiety Disorder

Denmark
The Cooper Health System

Withdrawn

Stereotactic Radiosurgery for Soft Tissue Sarcoma

Soft Tissue Sarcoma

United States
Cytokinetics

Terminated

Phase II Study of the Effect of CK-1827452 Injection on Myocardial Efficiency

Heart Failure

Canada, United States
Cytokinetics

Completed

Pharmacokinetics of Oral CK-1827452 in Patients With Stable Heart Failure

Heart Failure

Georgia
Cytokinetics
National Institute of Neurological Disorders and Stroke (NINDS)

Terminated

Pharmacodynamic Study of CK-2017357 in Patients With Generalized Myasthenia Gravis

Myasthenia Gravis

United States
Johnson & Johnson Consumer Inc. (J&JCI)

Completed

A Controlled Clinical Study of 2 Different Moisturizers for the Relief of Dry Skin

Skin Care | Skin | Skin Cream

United States
Astellas Pharma Global Development, Inc.
Cytokinetics

Completed

A Study to Assess the Effect of CK-2127107 on Physical Function in Subjects With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease (COPD)

United States
Astellas Pharma Global Development, Inc.
Cytokinetics

Terminated

A Study to Assess the Anti-fatigability Effect of CK-2127107 in Elderly Male and Female Subjects With Limitations in Mobility

Mobility Limitation

United States
Cytokinetics
Astellas Pharma Inc

Completed

A Study to Evaluate Efficacy, Safety and Tolerability of CK-2127107 in Patients With Amyotrophic Lateral Sclerosis (ALS) (FORTITUDE-ALS)

Amyotrophic Lateral Sclerosis

United States, Netherlands, Australia, Canada, Ireland, Spain
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.

Recruiting

An Open-Label Study of Aficamten for Chinese Patients With Symptomatic oHCM

Obstructive Hypertrophic Cardiomyopathy

China
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.
Cytokinetics

Completed

Safety, Tolerability and Pharmacokinetics Study of CK-3773274

Healthy Adult Subjects | Obstructive Hypertrophic Cardiomyopathy

China
Centre Antoine Lacassagne

Completed

Hypofractionated Radiation by CyberKnife as a Mean of the Tumor Site's Radiation After Conventional Breast Radiation. (CYBERBOOST)

Breast Cancer

France
Centre Francois Baclesse, Luxembourg

Active, not recruiting

IMRT Followed by CyberKnife Boost Focused on the Gross Residual Pelvic Tumor Volume (Boost_Pelvis)

Pelvis Tumors

Luxembourg
Seoul National University Hospital

Terminated

Neoadjuvant Chemotherapy Response in Metaplastic Carcinoma of Triple Negative Breast Cancer (NEO-SMART)

Metaplastic Breast Carcinoma

Korea, Republic of
Wang Hongxia
Tianjin Eye Hospital

Unknown

Comparison of Anterior Corneal Optical Aberration Induced by CK and Hyperopic LASIK

Refractive Error

China
Cytokinetics
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.

Completed

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic oHCM (SEQUOIA-HCM) (SEQUOIA-HCM)

Obstructive Hypertrophic Cardiomyopathy (oHCM)

United States, France, Spain, Portugal, Germany, China, United Kingdom, Israel, Netherlands, Denmark, Czechia, Hungary, Italy, Poland
Cytokinetics

Enrolling by invitation

Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCM (FOREST-HCM)

Symptomatic Hypertrophic Cardiomyopathy (HCM)

United States, France, Israel, Spain, United Kingdom, Italy, Portugal, Poland, Hungary, Denmark, Netherlands, Germany, Czechia
Cytokinetics

Completed

Ventilatory Investigation of Tirasemtiv and Assessment of Longitudinal Indices After Treatment for a Year (VITALITY-ALS)

Amyotrophic Lateral Sclerosis

Canada, United States, Netherlands, France, United Kingdom, Belgium, Germany, Spain, Ireland, Italy, Portugal
ChemRar Research and Development Institute, LLC

Not yet recruiting

A Study to Assess the Efficacy and Safety of CD-008-0045 in Patients With Generalized Anxiety Disorder

Anxiety Disorder Generalized
Cytokinetics

Completed

Study to Evaluate the Safety and Efficacy of IV Infusion Treatment With Omecamtiv Mecarbil in Subjects With Left Ventricular Systolic Dysfunction Hospitalized for Acute Heart Failure (ATOMIC-AHF)

Heart Failure

United States, Canada, Germany, Italy, Netherlands, Belgium, France, Czechia, Australia, Russian Federation, Hungary, Poland, Bulgaria, Slovakia, United Kingdom, Finland, Greece, Lithuania, Norway
Cytokinetics

Completed

Study to Assess the Effect of Omecamtiv Mecarbil on Exercise Capacity in Subjects With Heart Failure (METEORIC-HF)

Heart Failure With Reduced Ejection Fraction

United States, Hungary, France, Canada, Netherlands, Germany, Poland, Italy, Sweden
Checkpoint Therapeutics, Inc.

Completed

Phase I/II Study of CK-101 in NSCLC Patients and Other Advanced Solid Tumors

Lung Diseases | Adenocarcinoma | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms

United States, Thailand, New Zealand, Australia, Poland
Biosite

Withdrawn

Rapid Assessment of Cardiac Markers for the Evaluation of Acute Coronary Syndrome (RACE-ACS)

Acute Coronary Syndrome

United States
Georgetown University

Terminated

CyberKnife Stereotactic Accelerated Partial Breast Irradiation (SAPBI) (CK-SAPBI)

Breast Cancer | DCIS | Invasive Ductal Carcinoma

United States
Centre Antoine Lacassagne

Completed

Stereotactic Radiosurgery in Treating Patients Undergoing Chemotherapy and Radiation Therapy For Stage III Non-Small Cell Lung Cancer

Lung Cancer

France
Cytokinetics
Astellas Pharma Global Development, Inc.

Completed

A Study of CK-2127107 in Patients With Spinal Muscular Atrophy

Spinal Muscular Atrophy

United States, Canada
Fougera Pharmaceuticals Inc.

Withdrawn

Study Comparing Product 0405 to a Vehicle Control in the Treatment of Mild to Moderate Atopic Dermatitis in Pediatric Subjects

Atopic Dermatitis
Fougera Pharmaceuticals Inc.

Withdrawn

Study Comparing Product 0405 to a Vehicle Control in the Treatment of Mild to Moderate Atopic Dermatitis in Pediatric Subjects

Atopic Dermatitis
University Hospital, Clermont-Ferrand

Unknown

Impact of Early Lactate Dosage Compared to CK for Diagnosis of a Suspected Seizure

Creatine Kinase | Lactate | Epileptic Seizure | Epileptic Generalized Tonic-clonic Seizure

France
Turning Point Therapeutics, Inc.

Withdrawn

A Phase 1 Study to Assess the Effect of Hepatic Impairment on the Pharmacokinetics of Repotrectinib in Advanced Cancer Patients

Metastatic Solid Tumor | Locally Advanced Solid Tumor

United States, Spain
Turning Point Therapeutics, Inc.

Recruiting

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

Lymphoma | Locally Advanced Solid Tumors | Metastatic Solid Tumors | Primary CNS Tumors

United States, Korea, Republic of, Spain, Singapore, Taiwan, Australia, Italy, Canada, France, Denmark, United Kingdom
Georgetown University

Unknown

A Multi-Institutional Registry for CyberKnife Stereotactic Accelerated Partial Breast Irradiation (CK-SAPBI)

Breast Cancer

United States
GPCR Therapeutics, Inc.

Completed

Safety and PK/PD of TG-0054 in Multiple Myeloma, Non-Hodgkin Lymphoma and Hodgkin Disease Patients

Multiple Myeloma | Hodgkin Disease | Non-Hodgkin Lymphoma

Taiwan
Pharmaceutical Project Solutions, Inc.
Cognitive Research Corporation

Completed

PK Study of Intranasal RX0041-002 in Subjects With Severe Renal Impairment and Normal Renal Function

Healthy

United States
Turning Point Therapeutics, Inc.

Terminated

Study of TPX-0046, A RET/SRC Inhibitor in Adult Subjects With Advanced Solid Tumors Harboring RET Fusions or Mutations

Non Small Cell Lung Cancer | Advanced Solid Tumor | Metastatic Solid Tumor | Medullary Thyroid Cancer | RET Gene Mutation

United States, Korea, Republic of
GPCR Therapeutics, Inc.

Completed

Evaluating the Safety, Tolerability, Pharmacokinetics and Efficacy of TG-0054 With Single IV Doses Escalation in Healthy Volunteers

Healthy

United States
Fougera Pharmaceuticals Inc.

Withdrawn

Study to Determine the Pharmacokinetics of Product 0405

Atopic Dermatitis
Seelos Therapeutics, Inc.

Withdrawn

SLS-005 (Trehalose Injection) in the Treatment of Alzheimer's Disease ([STRIVE-AD])

Alzheimer's Disease

Australia

Search clinical trials for: CK-0045

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