Search clinical trials for: cyclosporine

Total 978 results

Institute of Rheumatology, Prague
Charles University, Czech Republic; Palacky University; Ministry of Health, Czech... and other collaborators

Completed

Cyclosporine A or Intravenous Cyclophosphamide for Lupus Nephritis: The Cyclofa-Lune Study (CYCLOFA-LUNE)

Systemic Lupus Erythematosus | Lupus Nephritis

Czech Republic
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Melphalan and Stem Cell Transplant Before Total-Body Irradiation and Donor Stem Cell Transplant in Treating Patients With Stage I-III Multiple Myeloma

Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Refractory Multiple Myeloma

United States, Italy
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Alemtuzumab, Fludarabine Phosphate, and Low-Dose Total Body Irradiation Before Donor Stem Cell Transplantation in Treating Patients With Hematological Malignancies

Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent... and other conditions

United States, Italy
Zambon SpA

Active, not recruiting

Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Single Lung Transplant (BOSTON-1) (BOSTON-1)

Bronchiolitis Obliterans | Lung Transplant Rejection | Lung Transplant; Complications | Lung Transplant Failure and Rejection | Chronic Rejection of Lung Transplant | Chronic Lung Allograft Dysfunction

France, United States, Spain, Israel, Belgium, United Kingdom, Germany
Hanlim Pharm. Co., Ltd.

Completed

Study of Cyclosporine Ophthalmic Soution Group and Cyclosporine Ophthalmic Suspension Group (Cyclosporine)

Dry Eye Syndromes

Korea, Republic of
Astellas Pharma Inc
Astellas Pharma Canada, Inc.

Completed

Comparison of Extended Release Tacrolimus (Advagraf) and Cyclosporine A Microemulsion on Renal Function in Healthy Volunteers

Healthy

Canada
Julian M. Mackay-Wiggan
Allergan

Completed

Restasis for Treatment of Brittle Nails

Brittle Nails

United States
Semmelweis University

Unknown

Autoimmunity in Retinitis Pigmentosa

Retinitis Pigmentosa

Hungary
Heidelberg University
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Rapamycin Use in Calcineurin Inhibitor (CNI)-Free Immunosuppression for Stabilization/Improvement of Renal Function After Heart Transplantation

Renal Failure | Heart Transplantation

Germany
Baxalta now part of Shire

Terminated

Prevention of Graft-Versus-Host Disease in Patients With Advanced Leukemia or Lymphoma Who Are Eligible for Peripheral Stem Cell Transplantation

Lymphoma | Leukemia | Graft Versus Host Disease

United States, Australia
Hospital Authority, Hong Kong
Hoffmann-La Roche

Unknown

Mycophenolate Mofetil for the Prophylaxis of Graft-versus-host Disease in High Risk Allogeneic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation | Graft vs Host Disease

China
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Reduced-Intensity Conditioning Followed By Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Multiple Myeloma

Refractory Multiple Myeloma

United States, Italy
Fred Hutchinson Cancer Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cyclophosphamide and Anti-thymocyte Globulin Followed By Methotrexate and Cyclosporine in Preventing Chronic Graft-Versus-Host Disease in Patients With Severe Aplastic Anemia Undergoing Donor Bone Marrow Transplant

Aplastic Anemia

United States
Alexandria University

Completed

Topical Cyclosporine A for the Treatment of Dry Eye: A Randomized Clinical Study

Dry Eye
Novartis Pharmaceuticals

Completed

Efficacy, Safety and Evolution of Cardiovascular Parameters in Renal Transplant Recipients (ELEVATE)

Kidney Transplantation

Germany, Belgium, Netherlands, Australia, Austria, Italy, Spain, Thailand, Estonia, Norway, Lithuania, Turkey, Mexico, Argentina, Greece, Russian Federation, Portugal, France, India, Latvia, Romania
Novartis Pharmaceuticals

Terminated

Liver Fibrosis in Patients Transplanted for Hepatitis C Receiving Either Cyclosporine Microemulsion or Tacrolimus

Hepatitis C | Liver Transplant

United States, Switzerland
University Hospital, Antwerp
Wyeth is now a wholly owned subsidiary of Pfizer; Hoffmann-La Roche

Unknown

Fibrosis in Renal Allografts

Kidney Failure, Chronic | Immunosuppression | Transplantation | Interstitial Fibrosis

Belgium
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Brentuximab Vedotin, Cyclosporine, and Verapamil Hydrochloride in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma

Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma

United States
Hospices Civils de Lyon

Completed

Study of Methotrexate Efficacy Versus Cyclosporine in Moderate to Severe Atopic Dermatitis Patients (METHODA)

Atopic Dermatitis

France
West China Hospital

Recruiting

Mycophenolate Mofetil Versus Cyclosporin A in the Treatment of Primary Biliary Cholangitis-autoimmune Hepatitis Overlap Syndrome Due to Nonresponse to Standard Therapy

Hepatitis, Autoimmune | Immunosuppression | Primary Biliary Cholangitis

China
University Hospital Tuebingen

Completed

Interferon-alpha2a Versus Cyclosporin A for Severe Ocular Behcet's Disease (INCYTOB) (INCYTOB)

Panuveitis | Posterior Uveitis | Retinal Vasculitis | Behcet's Disease

Germany
Bristol-Myers Squibb

Completed

A Study of BMS-224818 (Belatacept) in Patients Who Have Undergone a Kidney Transplant and Are Currently on Stable Cyclosporine or Tacrolimus Regimen With or Without Corticosteroids

Renal Transplant

Argentina, Australia, India, United States, Belgium, Brazil, Poland, Mexico, Canada, France, Germany, Spain
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Effect of Sirolimus on Non-Melanoma Skin Cancer in Kidney Transplant Recipients

Kidney Transplantation | Skin Neoplasms

Australia, United States, Canada, New Zealand
Pfizer

Completed

A Phase I Open-Label Study of the Effects of Tacrolimus and Cyclosporine on CP-690,555 in Healthy Volunteers

Healthy Volunteers

Singapore
Hospital Universitario Dr. Jose E. Gonzalez

Recruiting

Evaluation of Safety & Efficacy for the Prevention of Ocular GVHD With Ophthalmic Tacrolimus vs Cyclosporine in Allo-HSCT

Ocular Graft-versus-host Disease

Mexico
Peking University Third Hospital

Recruiting

The Effect of 0.05% CsA Eye Drops on Post-refractive Surgery Dry Eye

Dry Eye

China
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Comparing Graft Function in Renal Allograft Recepients Receiving Reduced or Standard Dose CsA With Sirolimus

Kidney Transplantation
Federal University of São Paulo
Allergan

Completed

Safety Study of the Use of Topical Cyclosporine in the Treatment of Dry Eye Disease

Evaporative Dry Eye Disease | Primary Sjogren Syndrome | Secondary Sjogren Syndrome | Aqueous Deficient Dry Eye Disease

Brazil
National Taiwan University Hospital

Unknown

Sirolimus Blood Concentrations on Conversion From Oral Solution to Tablets

Kidney Transplantation | Immunosuppression | Transplantation

Taiwan
Beth Israel Deaconess Medical Center
Bayer

Completed

Nonmyeloablative Allogeneic Stem Cell Transplantation From HLA-Matched Unrelated Donor for the Treatment of Hematologic Disorders

Multiple Myeloma | Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | AML | Myelodysplastic Syndrome | Aplastic Anemia | Myeloproliferative Disorder | CLL | ALL

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Decitabine and Peripheral Stem Cell Transplantation in Treating Patients Who Have Relapsed Following Bone Marrow Transplantation for Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia

Myelodysplastic Syndromes | Leukemia

United States
Massachusetts General Hospital
Dana-Farber Cancer Institute

Terminated

Non-Myeloablative HLA-Matched Ex-Vivo T-cell Depleted Stem Cell Transplantation for Hematologic Malignancies

Lymphoma | Leukemia | Multiple Myeloma | Myelodysplastic Syndrome

United States
University Hospital, Brest
Novartis; Roche Pharma AG; Ministry of Health, France; Genzyme, a Sanofi Company

Completed

mTor-inhibitor (EVERolimus) Based Immunosuppressive Strategies for CNI Minimisation in OLD for Old Renal Transplantation (EVEROLD)

Renal Transplant

France
Weill Medical College of Cornell University
Celgene

Terminated

Efficacy and Safety of Lenalidomide in Combination With Cyclosporine A in Patients With Myelodysplastic Syndromes

Myelodysplastic Syndrome

United States
University of Aarhus

Completed

Diabetogenicity of Cyclosporine and Tacrolimus (CSATAC)

Complications of Transplanted Organs and Tissue | Diabetes Mellitus Nos New Onset

Denmark
Hannover Medical School

Unknown

Studying the Effect of Changing Immunosuppression in Case of Polyoma BK Virus Infection of the Renal Transplant (BKVIRUS)

Virus Diseases | Disorder Related to Renal Transplantation | Immunosuppression Related Infectious Disease

Germany
Organon and Co
Schering-Plough

Completed

MD Ezetimibe Cyclosporine Interaction (0653-057)

Cholesterol
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Comparing Therapies for the Treatment of Severe Aplastic Anemia

Severe Aplastic Anemia (SAA)

United States
Novartis Pharmaceuticals

Completed

Efficacy and Safety of AEB071 Versus Cyclosporine in de Novo Renal Transplant Recipients

Kidney Transplantation

Belgium, Taiwan, Italy, Germany, Spain, Switzerland, Australia, Singapore, Norway, Netherlands, Colombia, Argentina, Brazil, Austria, Slovakia, France, Czech Republic
Wyeth is now a wholly owned subsidiary of Pfizer

Terminated

Study Evaluating of Calcineurin Inhibitor and Sirolimus (Rapamune) Treatment in Liver Transplant Recipients

Liver Transplantation

Italy, Belgium, Spain, France, Canada, Germany, United States, United Kingdom, Portugal, Czech Republic, Switzerland, Netherlands
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Yttrium Y 90 Ibritumomab Tiuxetan, Fludarabine, Radiation Therapy, and Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma | Recurrent Adult Immunoblastic Large Cell Lymphoma | Recurrent Adult Lymphoblastic... and other conditions

United States
Université de Sherbrooke

Recruiting

Cyclosporine and Intense Pulsed Light for Dry Eye in Contact Lens Users (CycliP)

Dry Eye | Contact Lens Complication

Canada
Sohag University

Not yet recruiting

Cyclosporine Adverse Outcomes in Steroid Dependent and Frequent Relapsing Nephrotic Syndrome in Children;Single Center Study

Steroid Dependent and Frequent Relapsing Nephrotic Syndrome

Egypt
NeuroVive Pharmaceutical AB

Completed

A Study to Compare the Bioavailability and Pharmacokinetics of Cyclosporine After Intravenous Administration of NEUROSTAT®, a CREMOPHOR® EL-free Lipid Emulsion, and SANDIMMUNE® Injection (a Suspension of Cyclosporine in CREMOPHOR® EL) in Healthy Volunteers

Healthy

South Africa
Allergan

Completed

Efficacy Study of Cyclosporine Ophthalmic Emulsion in Patients With Dry Eye Disease

Keratoconjunctivitis Sicca

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Study to Test the Effect of Cyclosporine on the Immune System of Patients With Early HIV Disease

HIV Infections

United States
University of Utah
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Myocarditis Treatment Trial

Heart Diseases | Cardiovascular Diseases | Myocarditis
Yizhou Zheng

Unknown

A Single-Arm Phase 2 Study With Optimized Standard Protocol for Severe Aplastic Anemia (OSP)

Aplastic Anemia

China
Perle Bioscience, Inc.

Withdrawn

The Insulin Independence Trial (IIT) Evaluating the Safety and Efficacy of Oral Cyclosporine and Oral Lansoprazole for Insulin Independence Among Patients With Existing Type 1 Diabetes (IIT)

Type 1 Diabetes
Perle Bioscience, Inc.
Syreon Corporation

Withdrawn

The Insulin Independence Trial (IIT) Evaluating the Safety and Efficacy of Oral Cyclosporine and Oral Omeprazole for Insulin Independence Among Recent Onset Type 1 Diabetes Patients (IIT)

Type 1 Diabetes

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