Search clinical trials for: Complement Inactivating Agents

Total 188456 results

QuantumLeap Healthcare Collaborative
M.D. Anderson Cancer Center; University of Colorado, Denver; University of Pennsylvania and other collaborators

Recruiting

I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill Patients (I-SPY_COVID)

COVID-19

United States
Samsung Medical Center

Completed

Comparison of the Effects of Vecuronium and Cisatracurium on Electrophysiologic Monitoring During Neurosurgery

Brain Tumor | General Anesthesia | Cerebral Aneurysm | Neurosurgery | Spine Tumor | Motor Evoked Potential Monitoring

Korea, Republic of
RenJi Hospital

Recruiting

Pediatric Liver Transplantation-Liver Fibrosis Evaluation by Using Fibrosis Panel (PT-LiFE)

Liver Transplant; Complications | Liver Fibrosis | Pediatric Disorder

China
Tomsk National Research Medical Center of the Russian...

Not yet recruiting

Left Bundle Branch Pacing on Outcomes and Ventricular Remodeling in Biventricular CRT Nonresponders (RESCUE)

Heart Failure | Left Bundle-Branch Block | Ischemic Cardiomyopathy | Left Ventricular Dysfunction | Non-ischemic Dilated Cardiomyopathy | Left Ventricle Remodeling

Russian Federation
Chang Gung Memorial Hospital

Recruiting

Evaluation of 68Ga-FAPI-46 and 18F-FDG PET/CT Imaging for Detecting Recurrent Tumor Lesions in Patients of Ovarian Cancer

Ovarian Cancer

Taiwan
Second Affiliated Hospital of Xi'an Jiaotong University

Unknown

Dexmedetomidine Combined With the Closed Loop of Target Controlled Infusion of Propofol for Anesthesia With Intraoperative Wake up

Anesthesia; Reaction
National Cancer Institute (NCI)

Completed

Ixazomib and Pevonedistat in Treating Patients With Multiple Myeloma That Has Come Back or Does Not Respond to Treatment

Refractory Multiple Myeloma | Recurrent Multiple Myeloma

United States
Dr. Robert Tanzola

Completed

The Effect of Intraoperative Labetalol on Time to Discharge

Heart Rate | Bloodpressure

Canada
Light Sciences Oncology
Mundipharma Research Limited

Completed

A Placebo Controlled Study of MR901 (Talaporfin Sodium Sodium + a Drug-activating Device) for the Relief of Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia

Benign Prostatic Hyperplasia

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Pevonedistat and Decitabine in Treating Patients With High Risk Acute Myeloid Leukemia

Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Therapy-Related Acute Myeloid Leukemia

United States
University of Sao Paulo

Completed

Effects of Intravenous Lidocaine Associated With Magnesium Sulfate on the Cisatracurium-Induced Neuromuscular Block

Neuromuscular Block
National Taiwan University Hospital

Unknown

A Study Comparing the Supraglottic Airway Devices and Endotracheal Tube During Controlled Ventilation for Laparoscopic Surgery

The Comparison of the I-gel and Endotracheal Tube About in Different Ventilation Settings During Laparoscopic Surgery

Taiwan
National Cancer Institute (NCI)

Withdrawn

Pevonedistat With Azacitidine Versus Azacitidine Alone in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia
Monica Levy Andersen

Completed

Mother-caregivers of Children With Duchenne Muscular Dystrophy (DMDK)

Other Diseases or Conditions

Brazil
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Pevonedistat and Ibrutinib in Treating Participants With Relapsed or Refractory CLL or Non-Hodgkin Lymphoma

Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Recurrent Small Lymphocytic Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Chronic Lymphocytic Leukemia | Recurrent Non-Hodgkin Lymphoma | Refractory Non-Hodgkin Lymphoma | Richter Syndrome and other conditions

United States
Medical College of Wisconsin

Terminated

Pevonedistat, Azacitidine (or Decitabine), and Venetoclax for the Treatment of Patients With Acute Myelogenous Leukemia (PAVE)

Acute Myelogenous Leukemia

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Combination of Pevonedistat With Chemotherapy for Bile Duct Cancer of the Liver

Stage III Intrahepatic Cholangiocarcinoma AJCC v8 | Stage IIIA Intrahepatic Cholangiocarcinoma AJCC v8 | Stage IIIB Intrahepatic Cholangiocarcinoma AJCC v8 | Unresectable Hepatocellular Carcinoma | Metastatic Cholangiocarcinoma | Stage III Hepatocellular Carcinoma AJCC v8 | Stage IIIA Hepatocellular... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Azacitidine, Venetoclax, and Pevonedistat in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Acute Myeloid Leukemia | Polycythemia Vera | Essential Thrombocythemia | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Chronic Neutrophilic Leukemia | Myeloid Neoplasm | Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative | Myelodysplastic/Myeloproliferative... and other conditions

United States
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Pevonedistat, Irinotecan, and Temozolomide in Treating Patients With Recurrent or Refractory Solid Tumors or Lymphoma

Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Recurrent Lymphoma | Recurrent Malignant Solid Neoplasm | Recurrent Primary Central Nervous System Neoplasm | Refractory Primary Central Nervous System Neoplasm

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Metastatic Lung Non-Squamous Non-Small Cell Carcinoma | Unresectable Lung Non-Small Cell Carcinoma | Unresectable Lung Non-Squamous Non-Small Cell Carcinoma | Metastatic...

United States
First Affiliated Hospital Xi'an Jiaotong University

Unknown

Effects of Different Doses of Dexmedetomidine on Postoperative Cognitive Dysfunction in Elderly Hypertensive Patients

Postoperative Cognitive Dysfunction
University of Illinois at Chicago
University of California, Los Angeles; University of Chicago; Wellesley College; The Arc of Illinois

Enrolling by invitation

BEhavioral Health Stratified Treatment (BEST) Study for Youth With Intellectual and/or Developmental Disabilities (IDD) (BEST)

Depression | Anxiety | Transition

United States
Sylhet M.A.G.Osmani Medical College
University of Edinburgh

Completed

Adding Nebulized Salbutamol to Intravenous Atropine and Oxygen in OP Poisoning (SalbutamolOP)

Organophosphate Poisoning

Bangladesh
Geisinger Clinic
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

Collaborative Approach to Reach Everyone With Familial Hypercholesterolemia (CARE-FH) (CARE-FH)

Familial Hypercholesterolemia

United States
Karadeniz Technical University

Recruiting

Effect of Modified ERAS Protocol on Clinical Outcomes in Pediatric Patients With Appendectomy

Surgery | Appendicitis | ERAS

Turkey
M.D. Anderson Cancer Center
Bristol-Myers Squibb; National Cancer Institute (NCI); Iovance Biotherapeutics

Active, not recruiting

Autologous Tumor Infiltrating Lymphocytes MDA-TIL in Treating Patients With Recurrent or Refractory Ovarian Cancer, Colorectal Cancer, or Pancreatic Ductal Adenocarcinoma

Malignant Solid Neoplasm | Metastatic Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Platinum-Resistant Ovarian Carcinoma | Metastatic Pancreatic Ductal Adenocarcinoma | Metastatic Ovarian Carcinoma and other conditions

United States
EMS

Withdrawn

Efficacy and Safety of Atenas Association in the Treatment of Type II Diabetes Mellitus and Hypertension (ATENAS)

Type II Diabetes Mellitus | Hypertension Associated
Istanbul University - Cerrahpasa (IUC)

Not yet recruiting

Effects of Exercise Versus Topical Agents on Knee Osteoarthritis

Osteo Arthritis Knee

Turkey
Fudan University

Unknown

Albumin-Bound Paclitaxel Followed by Epirubicin in Combination With Cyclophosphamide in Triple Negative Breast Cancer

Triple Negative Breast Cancer

China
University of Southern California
National Cancer Institute (NCI)

Active, not recruiting

Pevonedistat, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemia

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Therapy-Related Acute Myeloid Leukemia | Acute Myeloid Leukemia With Myelodysplasia-Related Changes

United States
Fuzhou General Hospital

Not yet recruiting

ctDNA as a Biomarker for Treatment in Advanced NSCLC

Non-small Cell Lung Cancer

China
Ain Shams University

Completed

A Clinical Study for the Effect of 4th Generation Poly AmidoAmine Dendrimer on Post-Bleaching Hypersensitivity and Shade Stability

Tooth Hypersensitivity

Egypt
Norwegian Institute of Public Health
University of Oslo; Oslo University Hospital; Oslo Municipality

Active, not recruiting

Does the New Fall- and Fracture Prevention Initiative in Oslo Have Effect?

Hip Fractures | Fall Injury
Universita di Verona

Completed

A Topical Desiccant Agent in Association With Manual Debridement in the Treatment of Peri-implant Mucositis

Peri-implant Mucositis

Italy
Samsung Medical Center

Withdrawn

Inhaled Amikacin Treatment for Nontuberculous Mycobacterial Lung Disease

Pulmonary Non-tuberculous Mycobacterial Lung Disease

Korea, Republic of
Oblato, Inc.

Withdrawn

Investigation of Oral OKN-007 in Recurrent High-grade Glioma Participants

Glioblastoma | Astrocytoma | Oligodendroglioma
Centre hospitalier de l'Université de Montréal...

Recruiting

Attribution of Toxicities Due to Radiotherapy and Immuno-Biological Therapies (AtTRIBut)

Cancer | Radiotherapy Side Effect

Canada
Pakistan Institute of Medical Sciences

Completed

Efficacy of Nanoparticle-incorporated Bonding Agent on Post-restorative Sensitivity

Carious Lesion

Pakistan
Pfizer

Completed

Phase 1 Study To Evaluate Antiviral Activity Of Small Molecule Direct Antiviral Agent At Multiple Doses In Subjects With Chronically Infected Hepatitis C Virus.

Hepatitis, Chronic | Hepatitis C Virus

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Millennium Pharmaceuticals, Inc.

Active, not recruiting

Bortezomib After Combination Chemotherapy, Rituximab, and an Autologous Stem Cell Transplant in Treating Patients With Mantle Cell Lymphoma

Mantle Cell Lymphoma

United States
Centre Hospitalier Universitaire de Nice

Completed

Treatment of Bullous Pemphigoid With Avdoralimab (IPH5401), an Anti-C5aR1 Monoclonal Antibody (IPH)

Bullous Pemphigoid

France
University of Athens

Unknown

Effects of Interleukin-6 Inhibition on Vascular, Endothelial and Left Ventricular Function in Rheumatoid Arthritis

Inflammation | Rheumatoid Arthritis

Greece
University of Louisville
Healthpoint

Completed

Comparison of Wound Bed Establishment in Facial Burns

Burns

United States
University of Virginia

Unknown

Evaluation of Renal Blood Flow Using Contrast Enhanced Ultrasound for Differential Diagnosis of Acute Kidney Injury in Cirrhotic Patients: A Pilot Study

Liver Cirrhosis and Acute Kidney Injury

United States
Zhongshan Ophthalmic Center, Sun Yat-sen University

Unknown

Effects of Adding Triamcinolone Acetonide to Conbercept Treatment for Refractory Diabetic Macular Edema (CONTE) (CONTE)

Diabetes Mellitus, Type 2 | Macular Edema

China
Yonsei University

Unknown

Yonsei OCT (Optical Coherence Tomography) Registry for Evaluation of Efficacy and Safety of Coronary Stenting

Coronary Artery Disease | Ischemic Heart Disease

Korea, Republic of
Boehringer Ingelheim

Completed

Tolerability and Potential ECG Effects After a Single Oral Dose of Pentoxyverine Citrate in Healthy Male and Female Volunteers

Healthy
Tamil Nadu Dr.M.G.R.Medical University

Recruiting

Evaluation of Gluma Desensitizer in Post-treatment Sensitivity in Posterior Composite

Sensitivity, Tooth

India
Institute of Tropical Medicine, Belgium
Drugs for Neglected Diseases; Medecins Sans Frontieres, Netherlands; Addis Ababa... and other collaborators

Completed

Prophylaxis of Visceral Leishmaniasis Relapses in HIV Co-infected Patients With Pentamidine: a Cohort Study

HIV-infection/Aids | Visceral Leishmaniosis

Ethiopia
The First Affiliated Hospital of Zhengzhou University

Recruiting

Adebrelimab Plus Cetuximab and Chemotherapy for Patients With RAS/BRAF Wild-Type Unresectable Liver Metastases Colorectal Cancer

Metastatic Colorectal Cancer

China

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