Search clinical trials for: Dapagliflozin/metformin XR 10/1000mg

Total 512 results

Dong-A ST Co., Ltd.

Completed

A Clinical Trial to Investigate Safety/Tolerability and Pharmacokinetics of DA-1229_01 Compared to Co-administration of Evogliptin 5 mg and Metformin XR 1000 mg, and to Evaluate the Effect of Food on the Pharmacokinetics of DA-1229_01 in Healthy Male Volunteers

Type 2 Diabetes Mellitus

Korea, Republic of
Woman's
AstraZeneca

Completed

Saxagliptin + Metformin Compared to Saxagliptin or Metformin Monotherapy in PCOS Women With Impaired Glucose Homeostasis (BMS-AZPCOS)

Polycystic Ovary Syndrome | Disorder of Glucose Regulation

United States
SINA Health Education and Welfare Trust
Horizon Pharmaceutical Pvt Ltd

Completed

Evaluating the Efficacy and Safety of Empagliflozin Addition to Insulin and Oral Antidiabetic Medication (OAD) Regimen in Poorly Controlled Type 2 Diabetes and Obese Patient

Glucose Metabolism Disorders | Diabetes Mellitus, Type 2 | Hypoglycemic Agents | Empagliflozin

Pakistan
BC World Pharm Co. Ltd.

Completed

Evaluating of Pharmacokinetic Profile of BCWP_C003 and Co-administration of Rosuvastatin and Metformin

Healthy

Korea, Republic of
James Wang
United States Department of Defense

Recruiting

Managing Chronic Tendon Pain by Metformin

Chronic Pain | Tendinopathy | Achilles Tendinopathy

United States
Boehringer Ingelheim

Completed

Bioequivalence of Empagliflozin and Metformin Given as a Fixed Dose Combination Compared to Single Tablets

Healthy

Germany
Boehringer Ingelheim
Eli Lilly and Company

Completed

Safety and Efficacy Study of Empagliflozin and Metformin for 24 Weeks in Treatment Naive Patients With Type 2 Diabetes

Hyperglycemia | Diabetes Mellitus, Type 2

United States, Brazil, Canada, Czech Republic, Egypt, France, Germany, Guatemala, Korea, Republic of, Lebanon, Malaysia, Mexico, Peru, Philippines, Russian Federation, Serbia, Spain, Taiwan, Thailand, Turkey, United Kingdom
Sihuan Pharmaceutical Holdings Group Ltd.

Unknown

Janagliflozin Treat Type 2 Diabetes Mellitus (T2DM) Inadequately Controlled With Metformin

Diabetes Mellitus, Type 2

China
Klinikum Nürnberg

Recruiting

A Study to Investigate the Mechanistic Effects of Dapagliflozin Alone or in Combination With Balcinrenone, Compared to Balcinrenone and Placebo on Body Fluid and Electrolyte Handling and Energy Metabolism in Participants Over 50 Years of Age With Chronic Kidney Disease. (DapaBalci-Leap)

Chronic Renal Failure | Mechanistic Effects of SGLT2 Inhibition and/ or MR Antagonism on Body Fluid and Electrolyte Homeostatis

Germany, France
Shengjing Hospital

Completed

CANA/Met in Non-diabetic Women With PCOS

Polycystic Ovary Syndrome

China
Abramson Cancer Center of the University of Pennsylvania

Terminated

Phase II Study of Bexarotene in Patients With Acute Myeloid Leukemia (UPCC04407)

Acute Myeloid Leukemia

United States
AstraZeneca

Withdrawn

BE Study of the Fixed Dose Combination of 5 mg Saxagliptin and 500 mg Metformin HCl XR Tablet Relative to a 5 mg Saxagliptin (Onglyza™) Tablet and a 500 mg Metformin HCl XR (Glifage® XR Marketed in Brazil by Merck S.A.) Tablet Co-Administered to Healthy Subjects in the Fasted and Fed States

Type 2 Diabetes

Brazil
The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

Evaluation and Intervention of Cognitive Function in Patients With Diabetes Mellitus.

Type2 Diabetes
Centro Medico Nacional Siglo XXI IMSS

Unknown

Effectiveness of Dapagliflozin for Weight Loss

Diabetes Mellitus, Type 2 | PreDiabetes | Obesity, Morbid

Mexico
AstraZeneca

Completed

Bioequivalence Study of the Fixed Dose Combination of 5 mg Saxagliptin and 500 mg Metformin XR Tablet (Manufactured in Mt Vernon, IN) Relative to 5 mg Saxagliptin Tablet and 500 mg Metformin XR Tablet (Manufactured in Evansville, IN)

Diabetes Mellitus

United States
Janssen Research & Development, LLC

Completed

A Study of Canagliflozin and Metformin Immediate Release (50 mg/500 mg) FDC Tablets in Healthy Volunteers

Healthy

United States
Janssen Research & Development, LLC

Completed

A Study of Canagliflozin and Metformin Immediate Release (150 mg/500 mg) FDC Tablets in Healthy Volunteers

Healthy

United States
Duke University

Terminated

Metformin for the Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) (NAFLD)

Fatty Liver

United States
Eisai Co., Ltd.

Completed

A Study of APD356 (Lorcaserin) in Healthy Japanese Adult Subjects

Healthy Subjects

Japan
Medical University of Silesia

Unknown

The Effects of Hypolipemic and Antidiabetic Treatment on Cytokines (MSF)

Inflammation | Diabetes | Dyslipidemia | Cytokines

Poland
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of 2 Fixed Dose Combination Tablets of Canagliflozin and Metformin Immediate Release (IR) With Respect to the Individual Components of Canagliflozin and Metformin IR Tablets in Healthy Volunteers

Healthy

United States
Medical University of Vienna
Vienna Dialysis Center

Recruiting

SGLT2 Inhibition in Hemodialysis (DAPA-HD)

Diabetes Mellitus, Type 2 | Hemodialysis | Chronic Kidney Disease | Kidney Failure | Left Ventricular Hypertrophy

Austria
Cook County Health
Bristol-Myers Squibb

Completed

Outpatient Discharge Therapy With Saxagliptin+MetforminXR vs GlipizideXL for Type 2 Diabetes With Severe Hyperglycemia

Hyperglycemia | Diabetes Mellitus Type 2

United States
AstraZeneca

Completed

Study To Evaluate 24 Hour Blood Sugar Control (24-hour Mean Weighted Glucose) In Subjects That Are Taking Saxagliptin 5 mg Added Onto Metformin XR 1500 XR mg Compared To Subjects Taking Metformin XR 1500 mg Up-titrated To Metformin XR 2000 mg

Type 2 Diabetes

United States, Argentina, Mexico, Israel
Dong-A ST Co., Ltd.

Unknown

Observational Study to Evaluate the Efficacy and Safety of Suganon Tab. or Sugamet XR Tab.

Diabetes Mellitus, Type 2

Korea, Republic of
Oman Ministry of Health

Not yet recruiting

The Effect of Dapagliflozin on Weight Loss in Obese Adults Without Diabetes (DAPA-ANDO)

Obesity | Weight Loss | Effect of Drug | Dapagliflozin Adverse Reaction
AstraZeneca
Bristol-Myers Squibb

Completed

Efficacy and Safety of Dapagliflozin in Combination With Metformin in Type 2 Diabetes Patients

Type 2 Diabetes

Sweden, France, Italy, Mexico, South Africa, Spain, Germany, Netherlands, Argentina, United Kingdom
Indiana Hemophilia &Thrombosis Center, Inc.

Active, not recruiting

Metformin Use in Cardiac Fibrosis in PAI-1 Deficiency

Plasminogen Activator Inhibitor-1 Deficiency | Cardiac Fibrosis

United States
Handok Inc.

Completed

A Study to Evaluate the Effect of Food on Fixed-Dose Combination of MP-513 10 mg and Metformin XR 750 mg

Healthy Volunteers

Korea, Republic of
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

A Study to Assess the Bioequivalence of Fixed Dose Combination of HR20033 Relative to Co-administration of the Individual Components in Healthy Chinese Subjects

Type II Diabetes
Boehringer Ingelheim

Completed

A Study in Healthy Humans to Assess the Relative Bioavailability of One Fixed-dose Combination Tablet Empagliflozin/Metformin Versus Jardiance® Tablet and Glifage® Tablet Administered Together (InPedILD®)

Healthy

Brazil
Boehringer Ingelheim

Completed

Equivalence of Resorption of Empagliflozin/Metformin Administered as Combination Tablet Compared With Empagliflozin/Metformin as Single Tablets Administered Together

Healthy

Germany
Era's Lucknow Medical College

Completed

Metformin in Overweight Type 2 Diabetes Mellitus

Obesity | Type 2 Diabetes Mellitus

India
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Pharmacokinetic and Pharmacodynamic Study of Metformin and Canagliflozin in Healthy Adult Volunteers

Healthy
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Completed

Bioequivalence of Dapagliflozin 10 mg Tablets Under Fed Conditions

Healthy Subjects

Canada
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Completed

Bioequivalence of Dapagliflozin 10 mg Tablets Under Fasting Conditions

Healthy Subjects

Canada
Fundación Pública Andaluza para la Investigación...

Unknown

SGLT-2 Inhibition, Metabolomics and Cardiovascular/Kidney Disease

Type 2 Diabetes Mellitus

Spain
London Health Sciences Centre

Completed

Adderall XR and Processing Speed in Multiple Sclerosis (MS)

Multiple Sclerosis | Cognitive Impairment | Impaired Processing Speed

Canada
VA Office of Research and Development

Recruiting

Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes (VA-IMPACT)

Atherosclerosis | Prediabetic State | Metformin

United States
Boehringer Ingelheim

Withdrawn

Clinical Outcomes and Healthcare Cost and Resource Utilization (HCRU) in Patients With Type 2 Diabetes and Cardiovascular Disease on 2nd Line Empagliflozin Versus 2nd Line Sulfonylureas

Cardiovascular Diseases | Diabetes Mellitus, Type 2

United States
Glaser Pediatric Research Network
Elizabeth Glaser Pediatric AIDS Foundation

Unknown

Glaser Obesity Study

Obesity

United States
Maastricht University
AstraZeneca

Completed

Effects of 2 Weeks Treatment With Dapagliflozin in Subjects With an Impaired Glucose Homeostasis on Nocturnal Substrate Oxidation (MaasFlex)

Prediabetic State | Substrate Oxidation

Netherlands
Mylan Pharmaceuticals Inc

Completed

Food BE Study Metformin Hydrochloride ER Tablets 500 mg and Glucophage XR 500 mg

Healthy

United States
National Hepatology & Tropical Medicine Research...

Not yet recruiting

Assessment of Metformin as Adjuvant Therapy in Patients With Ulcerative Colitis

Inflammatory Bowel Diseases | Ulcerative Colitis

Egypt
University of Diyala

Completed

Variable Effects of Anti-diabetics on Stress Hyperglycemia Ratio

Type 2 Diabetes

Iraq
Instituto Nacional de Cardiologia Ignacio Chavez

Not yet recruiting

Empagliflozin for No-reflow Phenomenon in PCI for STEMI (EMPA-PCI)

STEMI | No-Reflow Phenomenon
Oxford University Hospitals NHS Trust
Cancer Research UK

Completed

Effect of Metformin on Breast Cancer Metabolism

Breast Cancer

United Kingdom
Dong Wha Pharmaceutical Co. Ltd.

Completed

This Study is to Compare and Evaluate the Safety and Pharmacokinetic Characteristics (PK) After Administration of DW6014 and Each Component(Empagliflozin and Metformin) in Healthy Adult Volunteers in Fast Condition.

Healthy Subjects

Korea, Republic of
Joint Stock Company "Farmak"

Completed

Fed Bioequivalence Study of 2 Metformin 1000 mg Prolonged Release Tablets in 28 Healthy Male and Female Volunteers

Pharmacokinetics

Czechia
Nottingham University Hospitals NHS Trust
University of Nottingham; Vertex Pharmaceuticals Incorporated; Cystic Fibrosis... and other collaborators

Completed

Gut Imaging for Function & Transit in Cystic Fibrosis Study 2 (GIFT-CF2)

Cystic Fibrosis

United Kingdom

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