Search clinical trials for: ERB-257

Total 3536 results

Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety and Pharmacokinetics of Ascending Single IV Doses of ERB-257

Healthy Subjects

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety and Pharmacokinetics (PK) of Ascending Single IV Doses of ERB-257 in Healthy Japanese Males

Healthy Subjects

Japan
National Cancer Institute (NCI)

Completed

Entinostat, Lapatinib Ditosylate and Trastuzumab in Treating Patients With Locally Recurrent or Distant Relapsed Metastatic Breast Cancer Previously Treated With Trastuzumab Only

Recurrent Breast Carcinoma | Invasive Breast Carcinoma | HER2/Neu Positive | Stage IV Breast Cancer AJCC v6 and v7

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety and Efficacy of ERB-041 on Reduction of Symptoms Associated With Endometriosis in Reproductive-Aged Women

Endometriosis | Dysmenorrhea | Pelvic Pain | Dyspareunia

Hong Kong, United States, Canada, Australia, United Kingdom, South Africa, Belgium
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating ERB-041 in Endometriosis in Reproductive-Age Women

Endometriosis

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating ERB-041 in Active Crohn's Disease

Crohn's Disease
Wyeth is now a wholly owned subsidiary of Pfizer

Withdrawn

Study Evaluating Orally Administered ERB-041 in Subjects With Active Interstitial Cystitis

Cystitis, Interstitial

United States, Austria, Germany
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study to Evaluate Multiple Doses of ERB-041 in Healthy, Female Japanese Subjects

Healthy

Japan
AbbVie

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of Multiple Subcutaneous Injections of ABBV-257 in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Germany
Mitsubishi Tanabe Pharma Corporation

Completed

Safety and Efficacy of MCC-257 in the Treatment of Diabetic Polyneuropathy

Diabetic Polyneuropathy
University Hospitals, Leicester
National Institute for Health Research, United Kingdom; University of Leicester

Completed

Barrett&Apos;s Intervention for Dysplasia by Endoscopy (BRIDE)

Barretts Esophagus | Esophageal High-Grade Intraepithelial Neoplasia | Esophageal Cancer Stage I

United Kingdom
Alkahest, Inc.

Completed

Study to Compare Safety and Tolerability of AKST1210 Column at 2 Blood Flow Rates in Subjects With ESRD on Hemodialysis

End-Stage Renal Disease

United States
Impax Laboratories, LLC

Completed

Pharmacokinetics and Pharmacodynamics of IPX054 in Subjects With Parkinson's Disease

Idiopathic Parkinson's Disease

United States
AstraZeneca

Completed

PET Study in Parkinson's Disease Patients

Parkinson's Disease

Sweden
National Cancer Institute (NCI)

Completed

Entinostat in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors

Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Recurrent Lymphoma | Recurrent Malignant Solid Neoplasm | Recurrent Primary Central Nervous System Neoplasm | Refractory Primary Central Nervous System Neoplasm | Brain Stem Neoplasm | Pineal Region Neoplasm | Recurrent Visual Pathway Glioma | Refractory Visual Pathway Glioma

United States
Hospices Civils de Lyon
Fondation pour la Recherche Médicale

Completed

CHRONIC OPTIC NEUROPATHY IN MULTIPLE SCLEROSIS

Chronic Optic Neuropathy in Multiple Sclerosis

France
National Cancer Institute (NCI)

Withdrawn

Testing a New Anti-cancer Drug Combination, Entinostat and GSK525762C, for Advanced and Refractory Solid Tumors and Lymphomas

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory B-Cell Non-Hodgkin Lymphoma | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Pancreatic Carcinoma | Refractory T-Cell Non-Hodgkin Lymphoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC... and other conditions
Pfizer

Completed

A Study To Observe Safety And Concentrations Of PF-05297909 And Proteins In Both Blood And Cerebrospinal Fluid After A Single Dose Of PF-05297909 In Healthy Adults

Healthy

United States
Centre hospitalier de l'Université de Montréal...

Completed

Study Comparing 25d ProCor Needle Versus the Standard 25g Needle for Biopsies Performed by EUS-FNA

Solid Lesion Biopsies

Canada
Ontario Clinical Oncology Group (OCOG)
Canadian Cancer Society (CCS)

Completed

A Trial to Evaluate the Improvement in Lung Cancer Patients Receiving Radiation With or Without Brachytherapy (BRACHY)

Non-small Cell Lung Cancer

Canada
Merck Sharp & Dohme LLC

Completed

A Long-term Study of ERN/LRPT (Extended Release Niacin/Laropiprant [MK0524A]) in Patients With Dyslipidemia (0524A-102)

Dyslipidemia
National Cancer Institute (NCI)

Completed

MS-275 and Azacitidine in Treating Patients With Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemia

Acute Myeloid Leukemia | Leukemia | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Myelodysplastic Syndrome | Secondary Myelodysplastic Syndrome | de Novo Myelodysplastic Syndrome

United States
Utah State University
University of North Carolina, Chapel Hill; International OCD Foundation

Completed

Combining Acceptance and Commitment Therapy With Exposure and Response Prevention to Enhance Treatment Engagement

Obsessive-Compulsive Disorder

United States
Mclean Hospital
Utah State University

Completed

Assessing Models of Exposure Therapy

Obsessive-compulsive Disorders and Symptoms

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Effects of Multiple Oral Doses of ERB-041 on Cardiac Repolarization in Healthy Subjects

Healthy | Long QT Syndrome

United States
Acotec Scientific Co., Ltd
Zhejiang University

Completed

ACOART RF CLOSURE:Radiofrequency for Varicose Veins of Lower Extremity in China

Varicose Veins of Lower Limb

China
Baylor College of Medicine

Withdrawn

Individual Versus Group Exposure With Response Prevention (ERP) for the Treatment of Obsessive Compulsive Disorder (OCD)

OCD

United States
Amanda Dandanell Juul

Recruiting

Navigation Endobronchial Ultrasound (NEBULA)

Lung Cancer

Denmark
Northwestern University
National Cancer Institute (NCI); Pfizer

Terminated

Palbociclib in Treating Patients With Metastatic HER-2 Positive Breast Cancer With Brain Metastasis

Stage IV Breast Cancer | Recurrent Breast Carcinoma | Estrogen Receptor Negative | HER2/Neu Negative | HER2/Neu Positive | Progesterone Receptor Negative | Breast Carcinoma Metastatic in the Brain

United States
National Cancer Institute (NCI)
Gynecologic Oncology Group

Completed

Trastuzumab in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer

Recurrent Uterine Corpus Carcinoma | Endometrial Adenocarcinoma | Stage III Uterine Corpus Cancer AJCC v7 | Stage IV Uterine Corpus Cancer AJCC v7 | ERBB2 Gene Amplification

United States
National Cancer Institute (NCI)

Completed

Azacitidine With or Without Entinostat in Treating Patients With Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemia

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia... and other conditions

United States
Maculaser Oy

Completed

Fundus Image-guided Focal Electroretinography, Usability Study

Healthy | Macular Degeneration | Macular Edema

Finland
Butler Hospital
National Institute of Mental Health (NIMH)

Completed

Transcranial Direct Current Stimulation Augmented Exposure and Response Prevention for Obsessive-Compulsive Disorder

Obsessive-Compulsive Disorder

United States
Masonic Cancer Center, University of Minnesota

Completed

Stem Cell Transplant w/Laronidase for Hurler

Mucopolysaccharidosis I | Hurler Syndrome

United States
Amgen

Terminated

Safety Study of AMG 557 in Subjects With Subacute Cutaneous Lupus Erythematosus

Cutaneous Lupus | Lupus

United States, Australia, Canada
Jason Martyn
Alberta Health services; University of Alberta; University of Calgary; Physiotherapy...

Unknown

Trimodal Prehabilitation for Cystectomy Patients to Enhance Post-operative Care (TPC-RCT)

Bladder Cancer | Nutrition Aspect of Cancer
Robin E. Miller
National Institute of General Medical Sciences (NIGMS); Thomas Jefferson University and other collaborators

Terminated

Omega-3 Fatty Acids in Sickle Cell Disease

Sickle Cell Disease

United States
Arcutis Biotherapeutics, Inc.

Completed

Safety and Efficacy of ARQ-252 Cream in Subjects With Chronic Hand Eczema

Chronic Hand Eczema

United States, Australia, Canada
University Hospital Tuebingen

Unknown

Influence of Hypoxia on Electroretingraphy (ERG) Measurements

ERG Under Hypoxia

Germany
National Cancer Institute (NCI)

Recruiting

Testing A New Anti-cancer Drug Combination, Entinostat and ZEN003694, for Advanced and Refractory Solid Tumors and Lymphomas

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Advanced Pancreatic Carcinoma | B-Cell Non-Hodgkin Lymphoma | Metastatic Pancreatic Carcinoma | Refractory B-Cell Non-Hodgkin Lymphoma | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Pancreatic Carcinoma | Refractory T-Cell... and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Azacitidine and Entinostat in Treating Patients With Advanced Breast Cancer

Recurrent Breast Carcinoma | Triple-Negative Breast Carcinoma | Male Breast Carcinoma | Stage IV Breast Cancer AJCC v6 and v7 | Stage IIIC Breast Cancer AJCC v7

United States
Tabba Heart Institute
InnoTherapy Inc

Recruiting

Low Dose Heparin Factorial Trial

Radial Artery Occlusion

Pakistan
Orthopaedic Associates of Michigan, PC
Grand Rapids Medical Education Partners

Completed

Early Weight Bearing Tarsometatarsal Fusion Study

Hallux Valgus

United States
Butler Hospital
National Institute of Mental Health (NIMH)

Completed

Development of a Behavioral Team Intervention for Obsessive Compulsive Disorder

Obsessive Compulsive Disorder
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Cu64-DOTA-trastuzumab PET and Markers Predicting Response to Neoadjuvant Trastuzumab + Pertuzum in HER2+ Breast Cancer

Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer | HER2 Positive Breast Carcinoma

United States
AbbVie

Completed

A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of ABBV-157 in Healthy Volunteers and in Participants With Chronic Plaque Psoriasis

Psoriasis

United States
Akros Pharma Inc.

Terminated

Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Oral Doses of JTT-252

Diabetes Mellitus

United States
National Cancer Institute (NCI)

Completed

Azacitidine and Entinostat in Treating Patients With Recurrent Advanced Non-Small Cell Lung Cancer

Stage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Recurrent Non-Small Cell Lung Carcinoma | Stage IV Non-Small Cell Lung Cancer

United States
National Cancer Institute (NCI)

Terminated

Azacitidine and Entinostat in Treating Patients With Stage I Non-Small Cell Lung Cancer That Has Been Removed By Surgery

Stage IA Non-Small Cell Lung Carcinoma | Stage IB Non-Small Cell Lung Carcinoma

United States
Jewish General Hospital

Withdrawn

ER2 and Deep Learning for Prediction of Adverse Health Outcomes

Emergencies

Canada

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