Search clinical trials for: Esketamine

Total 1321 results

Janssen Research & Development, LLC

Completed

A Study to Evaluate the Efficacy, Safety, and Tolerability of Intranasal Esketamine Plus an Oral Antidepressant in Elderly Participants With Treatment-resistant Depression (TRANSFORM-3)

Depressive Disorder, Treatment-Resistant

United States, France, Belgium, Spain, Poland, Bulgaria, South Africa, Finland, Brazil, Sweden, United Kingdom, Lithuania
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Efficacy, Safety, and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression (TRANSFORM-2)

Treatment-resistant Depression

United States, Poland, Germany, Spain, Czechia
Cliniques universitaires Saint-Luc- Université...

Recruiting

Risk Factors and Prevention of Severe Pain Upon Cessation of a Peripheral Nerve Block (PRPK)

Surgery

Belgium
University of California, San Francisco

Terminated

Acute Pain Management in Patients on Opioid Replacement Therapy

Pain, Acute | Opioid-use Disorder

United States
New York State Psychiatric Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Glutamatergic Modulation of Disordered Alcohol Use

Alcohol Dependence

United States
Albany Medical College

Unknown

Efficacy of Ketamine for Improvement in Postoperative Pain Control After Spinal Fusion for Idiopathic Scoliosis

Idiopathic Scoliosis | Post-operative Pain

United States
Universidade Federal de Goias

Unknown

Comparison of Peritonsillar Infiltration of Tramadol Ketamine and Placebo on Pediatric Posttonsillectomy Pain

Pain, Postoperative | Child, Only | Sleep Disorder; Breathing-Related

Brazil
Rabin Medical Center

Unknown

Comparison of Propofol/Alfentanil With Propofol/Ketamine (KET-001)

Lung Disease

Israel
Inonu University

Completed

Effects of Sevoflurane and Ketamine on QT in Electroconvulsive Therapy

Major Depression | Electroconvulsive Therapy

Turkey
Fayoum University Hospital

Completed

Opioid Free Anesthesia in Obese Patients.

Opioid Free Anesthesia

Egypt
Janssen Research & Development, LLC

Completed

A Study of Intranasal Esketamine Plus an Oral Antidepressant for Relapse Prevention in Adult Participants With Treatment-resistant Depression (SUSTAIN-1)

Depressive Disorder, Treatment-Resistant

United States, France, Poland, Belgium, Germany, Spain, Mexico, Turkey, Canada, Brazil, Estonia, Hungary, Slovakia, Sweden, Czechia
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Efficacy, Safety, and Tolerability of Fixed Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression (TRANSFORM-1)

Treatment-resistant Depression

United States, France, Belgium, Mexico, Canada, Brazil, Estonia, Hungary, Slovakia
Hospital for Special Surgery, New York

Completed

Spinal Versus General Anesthesia With Popliteal and Adductor Canal Blocks for Ambulatory Foot and Ankle Surgery. (LMA vs Spinal)

Pain | Spinal Anesthesia | Postoperative Nausea and Vomiting | General Anesthesia | Nerve Block

United States
Ramathibodi Hospital

Completed

Three-level Injection Paravertebral Block vs General Anesthesia in Mastectomy

Radical Mastectomy

Thailand
Brugmann University Hospital

Recruiting

Intraoperative Methadone for the Prevention of Postoperative Pain

Orthopedic Surgery

Belgium
Natalie Lockney

Recruiting

Gabapentin & Ketamine for Prevention/Treatment of Acute/Chronic Pain in Locally Advanced Head and Neck Cancer

Head and Neck Cancer | Locally Advanced Head and Neck Carcinoma

United States
New York State Psychiatric Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Recruiting

The Role of Brief Potent Glutamatergic Modulation in Addressing Problem Drinking

Alcohol Use Disorder

United States
National Institute of Mental Health (NIMH)

Recruiting

Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder

Depression | Major Depressive Disorder | Healthy Volunteer

United States
University of Texas Southwestern Medical Center

Completed

Etomidate Versus Ketamine for Emergency Endotracheal Intubation: a Prospective Randomized Clinical Trial (EvK)

Respiratory Arrest | Cardiopulmonary Arrest

United States
Assiut University

Unknown

Sedation During Pediatric Diagnostic Gastrointestinal Endoscopy Gastrointestinal Endoscopy

Sedation
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Recruiting

Glutamatergic Modulation to Facilitate the Behavioral Treatment of Cocaine Use Disorders

Cocaine Use Disorder

United States
Helse Møre og Romsdal HF

Recruiting

Does Subacromial Injection With Glutamate Receptor Antagonist, Ketamine, Attenuate Pain in Rotator Cuff Tendinopathy?

Chronic Pain | Rotator Cuff Tendinitis

Norway
King's College London

Completed

Glutamate and Opioid Mechanisms of Antidepressant Response to Ketamine (GO-MARK)

Depressive Disorder, Treatment-Resistant

United Kingdom
Meyer Children's Hospital
IRCCS Azienda Ospedaliero-Universitaria di Bologna; Azienda Ospedaliera Universitaria... and other collaborators

Terminated

Ketamine in Refractory Convulsive Status Epilepticus (KETASER01)

Status Epilepticus

Italy
Icahn School of Medicine at Mount Sinai

Completed

Ketamine and Nitroprusside for Depression

Depression

United States
Columbia University
National Institute of Mental Health (NIMH)

Completed

Ketamine in the Treatment of Depression

Major Depressive Disorder

United States
Mansoura University Hospital

Unknown

Ketamine Versus Propofol Effect on the Immune-mediatory Response for Abdominal Surgery

Major Abdominal Surgery
Cukurova University

Completed

Propofol-Ketamine vs Remifentanyl-Ketamine for Sedation in Pediatric Patients Undergoing Colonoscopy

Delayed Emergence From Anesthesia

Turkey
Huseyin Aksoy

Completed

Subcutaneous Wound Infiltration of Ketamine or Bupivacaine Pain Perception After Cesarean Section

Postoperative Pain

Turkey
Janssen Research & Development, LLC

Terminated

The Effect of Minocycline on Relapse After Successful Intravenous Ketamine/Minocycline-induced Symptoms Response in Subjects With Depression

Depressive Disorder

Spain, France, Belgium, Netherlands
Rigshospitalet, Denmark
Glostrup University Hospital, Copenhagen

Completed

The Effect of Intraoperative Ketamine on Opioid Consumption and Pain After Spine Surgery in Opioid-dependent Patients

Chronic Pain | Postoperative Pain | Analgesics

Denmark
University Hospital, Ghent

Completed

Multimodal Versus Opioid aNalgesia in carDiAc Surgery (MONDAY)

Postoperative Pain | Postoperative Delirium

Belgium
Andrew A Herring
University of California, Los Angeles; Oregon Health and Science University

Unknown

US-guided SAPB for Rib Fractures in the ED

Rib Fractures | Rib Fracture Multiple

United States
Johns Hopkins University
United States Department of Defense

Recruiting

Ketamine for Multiple Sclerosis Fatigue (INKLING-MS)

Multiple Sclerosis Fatigue

United States
Tel-Aviv Sourasky Medical Center

Recruiting

The Effect of Intravenous Ketamine on Non Suicidal Self Injuries.

Non Suicidal Self Injury

Israel
Icahn School of Medicine at Mount Sinai

Completed

Effect of Ketamine on Laboratory-induced Stress in Healthy Subjects

Healthy Volunteers

United States
VA Office of Research and Development

Completed

Ketamine for Treatment Resistant Late-Life Depression

Treatment Resistant Depressive Disorder

United States
Northwestern University

Completed

Does a Single Intravenous Dose of Ketamine Reduce the Need for Supplemental Opioids in Post-Cesarean Section Patients?

Ketamine Adverse Reaction | Effects of; Anesthesia, Spinal and Epidural, in Pregnancy | Complication of Labor and/or Delivery

United States
University of Milano Bicocca
Azienda Ospedaliera Universitaria Integrata Verona; Azienda Socio Sanitaria... and other collaborators

Recruiting

Dual Anti-glutamate Therapy in Super-refractory Status Epilepticus After Cardiac Arrest (SUPER-CAT)

Cardiac Arrest | Status Epilepticus

Italy
New York State Psychiatric Institute

Completed

NMDA Antagonists in Bipolar Depression

Bipolar Disorder

United States
VA Office of Research and Development

Recruiting

Ketamine-enhanced Prolonged Exposure Therapy in PTSD

PTSD

United States
Yale University
Nathan Kline Institute for Psychiatric Research; American Foundation for Suicide...

Terminated

Ketamine in Borderline Personality Disorder

Borderline Personality Disorder

United States
University of Missouri-Columbia

Terminated

Combined Ketamine/Propofol for Emergency Department Procedural Sedation

Procedural Sedation and Analgesia

United States
William Beaumont Hospitals

Terminated

Study of Immunomodulation Using Naltrexone and Ketamine for COVID-19 (SINK COVID-19)

Coronavirus Infections | COVID-19 | Acute Respiratory Distress Syndrome | Severe Acute Respiratory Syndrome (SARS)

United States
Johns Hopkins University
National Multiple Sclerosis Society

Completed

Ketamine for Treatment of MS Fatigue

Multiple Sclerosis | Fatigue

United States
University Hospital, Ghent

Completed

Evaluation of a New Protocol for Adult Procedural Sedation With Ketamine-propofol in a 1 on 4 Ratio

Procedural Sedation and Analgesia

Belgium
Ankara University

Completed

Effect of Ketamine+Propofol vs Remifentanyl+Propofol on Laryngeal Mask Insertion Conditions

Surgery

Turkey
Columbia University

Completed

Pharmacokinetic Alterations During ECMO

Acute Respiratory Failure

United States
King's College London
South London and Maudsley NHS Foundation Trust

Recruiting

Synaptic Imaging and Network Activity in Treatment Resistant Depression (SIGNATURE)

Depressive Disorder | Mood Disorders | Anhedonia | Bipolar Disorder | Depressive Disorder, Major | Depressive Disorder, Treatment-Resistant | Bipolar Disorder I | Bipolar Disorder II

United Kingdom
VA Pittsburgh Healthcare System

Completed

Influence of Anesthetic Technique on Acute and Chronic Neuropathic Pain

Chronic Pain | Hernia | Acute Pain | Anesthesia, Intravenous | Anesthesia, Intratracheal

Search clinical trials for: Esketamine

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