Search clinical trials for: Evolocumab Injections

Total 8374 results

Annapoorna Kini

Completed

Effect of Evolocumab on Coronary Plaque Characteristics (YELLOW III)

Coronary Artery Disease

United States
Afyonkarahisar Health Sciences University

Completed

The Efficacy of PRP Injection in the Treatment of Rotator Cuff Syndrome (PRP)

Musculoskeletal Diseases | Shoulder Pain | Rotator Cuff Tendinopathy | Rotator Cuff Syndrome

Turkey
Hospital General Universitario Gregorio Marañon

Completed

Evolocumab Versus LDL Apheresis in Patients With Hypercholesterolemia

Hypercholesterolemia

Spain
First Affiliated Hospital of Fujian Medical University

Recruiting

PCSK9 Inhibitor Treatment for Patients With SPG5

Hereditary Spastic Paraplegia Type 5

China
Amgen

Completed

Study to Assess in Home Use of Evolocumab (AMG 145) Administration Using Either an Automated Mini-doser or a Prefilled Autoinjector/Pen

Mixed Dyslipidemia | Primary Hypercholesterolemia

United States, Canada
Rigshospitalet, Denmark

Withdrawn

Vascular Inflammation and Cholesterol Lowering Therapy

Lipid Lowering, Vascular Inflammation

Denmark
Amgen
Organization of Teratology Information Specialists (OTIS) Research Center...

Terminated

Evolocumab Pregnancy Exposure Registry

Hypercholesterolemia; ASCVD; Pregnancy
Amgen

Completed

Study to Assess In-home Use of Evolocumab (AMG 145) Using a Prefilled Syringe or a Prefilled Autoinjector/Pen

Mixed Dyslipidemia | Primary Hypercholesterolemia

United States, Canada
First Affiliated Hospital Xi'an Jiaotong University

Completed

In-hospital Initiation of PCSK9 Inhibitor in Patients With Acute Myocardial Infarction

Coronary Disease
Amgen

Terminated

Safety and Efficacy of Evolocumab in Addition to Optimal Stable Background Statin Therapy in Chinese Participants With Primary Hypercholesterolemia and Mixed Dyslipidemia

Mixed Dyslipidemia | Primary Hypercholesterolemia

China
LIB Therapeutics LLC

Completed

Phase 3 Study to Evaluate the Efficacy and Safety of LIB003 With Evolocumab in HoFH

Homozygous Familial Hypercholesterolemia

United States, Israel, Norway, South Africa, Turkey, India
University Hospital Inselspital, Berne
Amgen; University of Bern

Completed

EVOlocumab for Early Reduction of LDL-cholesterol Levels in Patients With Acute Coronary Syndromes (EVOPACS) (EVOPACS)

Acute Coronary Syndrome

Switzerland
Leonardo Clavijo
Amgen

Unknown

Effect of Evolocumab in Functional Status and LDL Oxidation of Patients With Peripheral Arterial Disease (Evol-PAD)

Peripheral Arterial Disease

United States
Second Xiangya Hospital of Central South University

Not yet recruiting

PCSK9 Inhibitor on ACS Patients With Multivessel Disease and Relatively Low LDL-C Level in Chinese Population

Acute Coronary Syndrome
UMC Utrecht
Erasmus Medical Center; Academisch Medisch Centrum - Universiteit van Amsterdam... and other collaborators

Unknown

Effects of Evolocumab Versus Placebo Added to Standard Lipid-lowering Therapy on Fasting and Post Fat Load Lipids in Patients With Familial Dysbetalipoproteinemia (EVOLVE-FD)

Hyperlipoproteinemia Type III | Familial Dysbetalipoproteinemia
University Hospital, Grenoble

Recruiting

Impact of PCSK9 Inhibitors on Coronary Microvascular Dysfunction in Patients With Atherosclerotic Cardiovascular Disease Proved by Myocardial Ischemia and Needing Coronarography (MICROPROTECT)

Atherosclerotic Cardiovascular Disease

France
Radboud University Medical Center
Amgen

Recruiting

Functional Improvement of Coronary Artery Narrowing by Cholesterol Reduction With a PCSK9 Antibody (FITTER)

Coronary Artery Disease | Atherosclerosis of Coronary Artery

Netherlands
LIB Therapeutics LLC

Completed

Trial to Evaluate Efficacy and Safety of LIB003, Evolocumab and Alirocumab in High-risk CVD Patients (LIBerate-H2H)

Cardiovascular Diseases | Hypercholesterolemia

United States
Vivozon, Inc.

Completed

Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Post-operative Pain Following Gastrectomy

Post-Operative Pain

Korea, Republic of
University of Campinas, Brazil

Completed

EXpanded Combination of Evolocumab Plus Empagliflozin on Diabetes: EXCEED-BHS3 Trial (EXCEED-BHS3)

Diabetes Mellitus, Type 2 | Dyslipidemia Associated With Type II Diabetes Mellitus | Hypertension Arterial

Brazil
Vivozon, Inc.

Completed

Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Post-operative Pain Following Gastrectomy

Post-Operative Pain

Korea, Republic of
GlaxoSmithKline

Completed

In-patient Study With GSK716155 In Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States
Imperial College Healthcare NHS Trust
Imperial College London

Active, not recruiting

Effect of Evolocumab on Carotid Plaque Composition in Asymptomatic Carotid Artery Stenosis (EVOCAR-1) (EVOCAR-1)

Carotid Artery Stenosis

United Kingdom
PersonGen BioTherapeutics (Suzhou) Co., Ltd.
Second Affiliated Hospital of Soochow University

Recruiting

UTAA17 Injection in the Treatment of Relapsed/Refractory Multiple Myeloma

Relapsed/Refractory Multiple Myeloma

China
Vivozon, Inc.

Completed

Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Postoperative Pain Following Total Hip Arthroplasty.

Post-Operative Pain

Korea, Republic of
Indiana University

Completed

Prospective Study of Celiac Block Injection: 1 vs. 2

Pancreatic Cancer | Chronic Pancreatitis

United States
Zibo Central Hospital

Recruiting

Effect of PCSK9 Inhibitor on Retinal Microvessels in Patients With Coronary Heart Disease After Intensive Lipid-lowering Therapy

Adverse Effect of Cardiovascular Medications (Diagnosis)

China
Amgen

Completed

Evaluation of Evolocumab (AMG 145) Efficacy in Diabetic Adults With Hypercholesterolemia/Mixed Dyslipidemia (BANTING)

Type 2 Diabetes | Hypercholesterolemia | Mixed Dyslipidemia

United States, Italy, Belgium, Spain, Canada, Poland, Mexico
Roswell Park Cancer Institute

Completed

Bathing Bundle Regimen in Reducing Gynecological Surgical Site Infection in Patients Undergoing Surgery

Malignant Female Reproductive System Neoplasm

United States
Labrha
Statitec

Completed

Safety of Use of Pandora for Patients Suffering From Gonarthrosis (PANDORA1)

Knee Osteoarthritis

France
Icahn School of Medicine at Mount Sinai

Completed

Rosuvastatin and Evolocumab for Coronary Artery Disease (Yellow V)

Coronary Artery Disease

United States
Istituto Ortopedico Rizzoli

Recruiting

Homologous PRP vs Placebo in Knee Osteoarthritis in Over 65 Years Old Patients

Knee Osteoarthritis

Italy
Amgen
TIMI Study Group

Completed

LAPLACE-TIMI 57: Low-density Lipoprotein Cholesterol (LDL-C) Assessment With PCSK9 monoclonaL Antibody Inhibition Combined With Statin thErapy (LAPLACE)

Hyperlipidemia

United States, Canada, Denmark, Czechia, Hungary
Amgen

Completed

Monoclonal Antibody Against PCSK9 to Reduce Elevated Low-density Lipoprotein Cholesterol (LDL-C) in Adults Currently Not Receiving Drug Therapy for Easing Lipid Levels (MENDEL)

Hyperlipidemia

United States, Denmark, Australia, Belgium, Canada
University of Erlangen-Nürnberg Medical School

Completed

Effect of Evolocumab on Vascular Function (EVO)

Atherosclerotic Cardiovascular Disease

Germany
Amgen

Completed

Safety and Tolerability of Repatha® (Evolocumab) in Indian Participants With Homozygous Familial Hypercholesterolemia (RAMAN)

Homozygous Familial Hypercholesterolemia HoFH

India
Amgen

Completed

Monoclonal Antibody Against PCSK9 to Reduce Elevated LDL-C in Subjects Currently Not Receiving Drug Therapy for Easing Lipid Levels-2 (MENDEL-2)

Hyperlipidemia

United States, Denmark, Taiwan, Korea, Republic of, Australia, Belgium, Canada, South Africa, France, Turkey
Esperion Therapeutics, Inc.

Completed

Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) 180mg When Added to PCSK9 Inhibitor Therapy

Hypercholesterolemia

United States
Amgen

Completed

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects (GAUSS)

Hyperlipidemia

United States, Denmark, Australia, Belgium, Spain, Finland, Sweden, Canada
Rothman Institute Orthopaedics

Unknown

Study Comparing One Versus Two Cortisone Injections for Trigger Finger

Trigger Finger | Stenosing Tenosynovitis

United States
Amgen

Completed

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects-4 (GAUSS-4)

Hypercholesterolemia

Japan
Wuhan Union Hospital, China

Recruiting

High-Resolution Assessment of Extracranial Plaques in a Multiple Centers Evolocumab Randomized Study

Cerebral Atherosclerosis

China
Beijing Luhe Hospital

Recruiting

Effects of PCSK-9 Inhibitor Treatment Prior to Undergoing Primary Percutaneous Coronary Intervention in Patients With ST-segment Elevation Myocardial Infarction

STEMI

China
Amgen

Completed

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects -2 (GAUSS-2)

Hyperlipidemia

United States, Denmark, Belgium, Germany, Hong Kong, Netherlands, France, Australia, Canada, South Africa, United Kingdom, Spain, Poland, Switzerland
R-Pharm International, LLC
R-Pharm; Data Management 365; Keystat, LLC; Exacte Labs LLC

Recruiting

Efficacy and Safety of Olokizumab in Patients With Progressive Fibrosing Interstitial Lung Diseases

Lung Diseases, Interstitial

Russian Federation
Theravectys S.A.

Not yet recruiting

A Study to Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer

HPV-Related Cervical Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma

United States
Rehabilitace MUDr. Hasan Mezian s.r.o.

Unknown

Effectiveness of Ultrasound Guided Corticoanesthetic Injection in Carpal Tunnel Syndrome

Carpal Tunnel Syndrome

Czechia
University of Leipzig
Celgene Corporation

Recruiting

Efficacy of Luspatercept in ESA-naive LR-MDS Patients With or Without Ring Sideroblasts Who do Not Require Transfusions (LENNON)

Myelodysplastic Syndromes | Anemia

Germany
Federico II University

Recruiting

Evaluation of Adherence, Persistence and Efficacy of Treatment With PCSK9 Inhibitors in Italy (AT-TARGET-IT)

Hypercholesterolemia

Italy
Assistance Publique - Hôpitaux de Paris
Amgen; Action Research Group

Recruiting

Evolocumab or Normal Strategies to Reach LDL Objectives in Acute Myocardial Infarction Upbound to PCI (AMUNDSEN)

NSTEMI - Non-ST Segment Elevation MI | STEMI - ST Elevation Myocardial Infarction

France

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