Search clinical trials for: FRM-0334

Total 6644 results

FORUM Pharmaceuticals Inc

Unknown

Study to Assess the Safety, Tolerability, and Pharmacodynamic (PD) Effects of FRM-0334 in Subjects With Prodromal to Moderate Frontotemporal Dementia With Granulin Mutation

Granulin Mutation

Belgium, United States, France, Italy, Netherlands, United Kingdom
Genentech, Inc.

Terminated

A Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Effects of Single and Multiple Ascending Doses of GDC-0334 and the Effect of Food on the Pharmacokinetics of GDC-0334 in Healthy Adult Participants

Healthy Volunteers

United Kingdom
Novo Nordisk A/S

Completed

A Research Study Investigating How NNC0385-0434 is Tolerated in People With or Without High Cholesterol Levels

Healthy Volunteers | Hypercholesterolaemia

United Kingdom
Novo Nordisk A/S

Completed

A Research Study Looking at New Protein-based Tablets in Healthy Men - Oral Formulation II

Healthy Volunteers; High Cholesterol

United States
Assembly Biosciences

Completed

A First in Human Study to Assess Safety, Tolerability, Pharmacokinetics of ABI-4334 in Healthy Subjects

Chronic Hepatitis B

New Zealand
Genentech, Inc.

Completed

A Study to Determine the Bioavailability of Various Formulations of GDC-0134 in Healthy Female Participants of Non-Childbearing Potential

Healthy Volunteers

United States
Merck Sharp & Dohme LLC

Completed

A Placebo-Controlled Study of MK0634 in Patients With Overactive Bladder (0634-007)

Urinary Incontinence
Novo Nordisk A/S

Completed

A Research Study Looking at New Protein-based Tablets in Healthy Male Participants

Type 2 Diabetes | Healthy Volunteers | High Blood Cholesterol Levels

Germany, Canada
Eilean Therapeutics

Not yet recruiting

Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated Relapsed or Refractory Acute Myeloid Leukemia

AML With Gene Mutations

Australia
Sumitomo Pharma America, Inc.
Syneos Health

Terminated

A Study of DSP-0337 in Patients With Advanced Solid Tumors to Determine the Safety and the Pharmacokinetic Profile

Neoplasms

United States
Novo Nordisk A/S

Completed

A Research Study Looking at How the Medicine NNC0385-0434 Works in the Body of Healthy Japanese Men

Healthy Volunteers | Atherosclerotic Cardiovascular Disease

Japan
Novo Nordisk A/S

Completed

A Research Study Looking at the Effect of Food Intake on How the Medicine NN0385-0434 Behaves in the Body of Healthy Participants

Healthy Volunteers | Elevated Cholesterol | Established Atherosclerotic Cardiovascular Disease (ASCVD) or ASCVD Risk

Germany
Ono Pharmaceutical Co. Ltd

Completed

A Study to Investigate the Effects of Food and Morning Versus Evening on Single and Multiple Doses of ONO-5334 in Healthy Post Menopausal Women

Healthy Post Menopausal Women

United Kingdom
Novo Nordisk A/S

Completed

A Trial to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of NNC0215-0384 Administered to Subjects With Moderate to Severe Rheumatoid Arthritis

Inflammation | Rheumatoid Arthritis

Germany, Russian Federation, Poland, Hungary
Nanjing Leads Biolabs Co.,Ltd

Recruiting

A Phase I/II Clinical Trial of LBL-033 in the Treatment of Advanced Malignant Tumors

Advanced Malignant Tumors

China
Nanjing Leads Biolabs Co.,Ltd

Recruiting

A Phase I/II Clinical Trial of LBL-034 in Patients With Relapsed Refractory Multiple Myeloma

Relapsed/Refractory Multiple Myeloma

China
Acceleron Pharma, Inc., a wholly-owned subsidiary...

Active, not recruiting

A Study of MK-2225 / ACE-1334 in Participants With Systemic Sclerosis With and Without Interstitial Lung Disease (MK-2225-002)

Systemic Sclerosis With and Without Interstitial Lung Disease

United States, Canada, Italy, Switzerland
XRad Therapeutics Inc

Completed

Trial of XRD-0394, a Kinase Inhibitor, in Combination With Palliative Radiotherapy in Advanced Cancer Patients

Metastasis | Recurrent Cancer | Locally Advanced Solid Tumor

United States
Assistance Publique - Hôpitaux de Paris

Completed

Interest of elastoFRM With Force Measure by MRI on Patients With Hepatocellular Cancer (FORCE)

Hepatocellular Cancer

France
Novo Nordisk A/S

Terminated

A Research Study Looking Into Levels of the Medicine NNC0385-0434 in the Body and How Well it is Tolerated in Participants With Impaired Kidney Function Compared to Participants With Normal Kidney Function

Chronic Kidney Disease

Germany
IDEA AG

Completed

IDEA-033 Open Label Study

Joint Pain | Musculoskeletal Pain | Stiffness | Soft Tissue Inflammation in Designated Target Area(s)

Germany
Nirsum Labs
National Institute on Drug Abuse (NIDA)

Recruiting

Single Ascending Dose Study of NRS 033 in Healthy Volunteers

Healthy Volunteers

United States
Tacere Therapeutics, Inc.

Completed

Safety and Efficacy Study of Single Doses of TT-034 in Patients With Chronic Hepatitis C

Hepatitis C

United States
Beijing InnoCare Pharma Tech Co., Ltd.

Recruiting

A Study of ICP-033 in Patients With Advanced Solid Tumors

Patients With Advanced Solid Tumors

China
University of Malaya

Completed

Microbial Colonisation On Vacuum-Formed Retainers Constructed On Conventional Models And Three Dimensional (3D) Reconstructed Models

Orthodontic Appliance Complication

Malaysia
Novo Nordisk A/S

Completed

A Research Study Looking at How NNC0385-0434 Tablets Work to Lower Blood Cholesterol in People With Heart Disease or a High Risk of Heart Disease

Atherosclerotic Cardiovascular Disease

Germany, Poland, United States, Netherlands, Japan, Greece, Belgium
Assembly Biosciences

Not yet recruiting

A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-4334 in Subjects With Chronic Hepatitis B Virus Infection

Chronic Hepatitis B
Ono Pharma USA Inc

Completed

Controlled Study of ONO-5334 in Postmenopausal Women With Osteopenia or Osteoporosis

Osteoporosis | Osteopenia

Netherlands
IDEA AG

Completed

IDEA-033 Three Months Dose Finding in OA Followed by IDEA-033 Three Months Extension in OA

Osteoarthritis; Knee
University Hospital of North Norway
Stiftelsen Helse og Rehabilitering

Completed

Transcranial Direct Current Stimulation (tDCS) as Treatment Method for Pain in Fibromyalgia

Fibromyalgia

Norway
Genentech, Inc.
Quotient Clinical

Completed

Bioavailability of GDC-0134 and the Effect of Food and Proton Pump Inhibitor on Pharmacokinetics of GDC-0134 in Healthy Female Participants

Amyotrophic Lateral Sclerosis

United Kingdom
Merck Sharp & Dohme LLC

Unknown

Multiple Dose Trial of MK-4334 in Participants With Alzheimer's Clinical Syndrome (MK-4334-005)

Mild Cognitive Impairment | Alzheimer's Disease
Solvay Pharmaceuticals

Completed

Study to Investigate ADME of 14C Labeled SLV334 After an i.v. Infusion

Pharmacology, Clinical

Netherlands
Alios Biopharma Inc.

Completed

A Study of AL-034 to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Doses in Healthy Participants

Hepatitis B

New Zealand
Azelon Pharmaceuticals

Unknown

Study to Evaluate Effect of Intranasal Teriparatide on Serum P1NP, a Biomarker of Bone Formation, in Postmenopausal Women With Low Bone Mass

Osteoporosis | Osteopenia
Amgen

Completed

AMG 334 20160172 Pediatric Migraine PK Study.

Migraine

United States
Cambridge Glycoscience

Completed

A Study Assessing the Tolerable Upper Intake Level and Safety of Sugars From Fiber

Gastrointestinal Tolerance

Ireland
University of Phayao
National Innovation Agency (NIA)

Completed

Effect of Cordyceps Militaris Beverage on the Immune Response

Healthy

Thailand
Bayer

Completed

Evaluation of the Stinging Potential of Products in Human Eyes

Sunscreen Agents

United States
IDEA AG

Completed

An Effectiveness and Safety Study of IDEA-033 in Comparison to Oral Naproxen and Placebo for the Treatment of Osteoarthritis of the Knee

Osteoarthritis, Knee

United States
Soovu Labs Inc.
University of Washington; Northern California Research Corporation

Completed

High Level Pulsed Heat Versus Low Level Steady Heat in Subjects With Chronic Low Back Pain

Low Back Pain | Chronic Pain | Analgesia | Heat

United States
Novo Nordisk A/S

Completed

Safety of NNC 0123-0000-0338 in Healthy Subjects

Healthy | Diabetes

Germany
Novo Nordisk A/S

Completed

First Human Dose Trial of NNC0215-0384 in Subjects With Rheumatoid Arthritis

Inflammation | Rheumatoid Arthritis

Germany
The Alfred E. Mann Foundation for Scientific Research

Terminated

Feasibility of the Radio-Frequency Microstimulator System to Improve Arm Function Following Traumatic Brain Injury

Traumatic Brain Injury

United States
University of Oxford
Stanley Medical Research Institute

Completed

Prevention of Mood Disorders by Folic Acid Supplementation (PRE-EMPT)

Depression | Bipolar Disorder

United Kingdom
Boston Scientific Corporation

Terminated

A Study of Orally Administered BGC20-0134 (Structured Lipid) in Patients With Relapsing Remitting Multiple Sclerosis (RRMS)

Relapsing Remitting Multiple Sclerosis

Spain, Germany, Belgium, Poland, France, Russian Federation
Hôpital NOVO

Completed

Evaluation of Positioning Protocols on a Wheelchair in Hemiplegic Patients (POSIT-HEMI)

Hemiplegia and/or Hemiparesis Following Stroke

France
Philogen S.p.A.
Immatics Biotechnologies GmbH

Terminated

F16IL2 Plus Paclitaxel in Metastatic Merkel Cell Carcinoma

Merkel Cell Carcinoma

Germany, Austria, Denmark, France, Spain, United Kingdom
Washington University School of Medicine

Active, not recruiting

Returning Research Results That Indicate Risk of Alzheimer Disease Dementia to Healthy Participants in Longitudinal Studies (WeSHARE)

Alzheimer Disease | Dementia of Alzheimer Type

United States
Hangzhou ACEA Pharmaceutical Research Co., Ltd.

Completed

Study to Investigate the Absorption, Metabolism and Excretion of [14C] AC0010 in Patients With Advanced NSCLC

Carcinoma, Non-Small-Cell Lung

China

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