Search clinical trials for: GS1-144

Total 4269 results

Changchun GeneScience Pharmaceutical Co., Ltd.

Recruiting

A Phase I Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Oral Dose Escalation of GS1-144 Tablets and the Effects of Food on the Pharmacokinetics of GS1-144 in a Chinese Population

Healthy Volunteer | Vasomotor System; Labile

China
Changchun GeneScience Pharmaceutical Co., Ltd.
Syneos Health

Recruiting

A Study to Assess Safety and Tolerability of GS1-144 in Healthy Volunteers

Vasomotor Symptoms | Adult Healthy Volunteers

Australia
Rachel Lieberman

Terminated

Capsular Tension Rings in Intraocular Lens Rotation

Cataract | Ophthalmoplegia | Ophthalmologic Complication

United States
Vivozon, Inc.

Completed

Absorption, Metabolism, Excretion, and Mass Balance Study of [14C]-VVZ-149 in Healthy Adult Male Subjects

Healthy Adult Male

United States
Sanwa Kagaku Kenkyusho Co., Ltd.

Completed

Bioavailability of [14C]-SK-1404 ADME & IV Microtracer Study

Nocturia

United Kingdom
Iovance Biotherapeutics, Inc.

Recruiting

Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors

Squamous Cell Carcinoma of the Head and Neck | Metastatic Melanoma | Non-small Cell Lung Cancer

United States, Spain, Canada, France, Germany, Greece, Switzerland, United Kingdom
Taisho Pharmaceutical Co., Ltd.

Completed

Mass Balance Study of TS-142 in Healthy Adult Subjects.

Healthy Male Subjects

Japan
U.S. Army Medical Research and Development Command

Completed

Safety and Immunogenicity Study of Eastern Equine Encephalitis (EEE) Vaccine (EEE)

Eastern Equine Encephalitis

United States
U.S. Army Medical Research and Development Command

Completed

Safety and Immunogenicity Study of the Eastern Equine Encephalitis (EEE) Vaccine

Eastern Equine Encephalitis

United States
Iovance Biotherapeutics, Inc.

Completed

Study of LN-145/LN-145-S1 Autologous Tumor Infiltrating Lymphocytes in the Treatment of Squamous Cell Carcinoma of the Head & Neck

Squamous Cell Carcinoma of the Head and Neck

United States
Memorial Sloan Kettering Cancer Center
Iovance Biotherapeutics, Inc.

Recruiting

Pilot Trial of Autologous Tumor Infiltrating Lymphocytes (LN-144) for Patients With Metastatic Uveal Melanoma

Melanoma | Metastatic Melanoma | Metastatic Uveal Melanoma | Uveal Melanoma

United States
IlDong Pharmaceutical Co Ltd

Unknown

Study to Evaluate Pharmacokinetics, Safety, and Tolerability Ildong COL-144 Tablet in Korean Healthy Volunteers

Healthy
GlaxoSmithKline

Completed

An Exercise Endurance Study to Evaluate the Effects of Treatment of Chronic Obstructive Pulmonary Disease (COPD) Patients With a Dual Bronchodilator: GSK573719/GW642444. Study A (COPD)

Pulmonary Disease, Chronic Obstructive

Germany, Russian Federation, United States, Bulgaria, Estonia, United Kingdom
Asan Foundation

Completed

Safety, Pharmacokinetics, Biodistribution, and Diagnostic Performance of [18F]GP1 PET in Thromboembolism

Thromboembolism

Korea, Republic of
Avilex Pharma

Completed

A Phase 1 Study in Healthy Volunteers to Evaluate the Safety, Tolerability and Pharmacokinetics of AVLX-144

Tolerance | Safety Issues

Finland
Instituto Dante Pazzanese de Cardiologia

Unknown

Great Saphenous Vein Electrocoagulation

Varicose Veins | Venous Disease

Brazil
General Hospital of Shenyang Military Region
The Third Xiangya Hospital of Central South University

Completed

An Exploratory Study of Ganglioside GM1 in Acute Ischemic Stroke

Stroke, Ischemic

China
Dracen Pharmaceuticals, Inc.

Terminated

Study to Investigate DRP-104 in Adults With Advanced Solid Tumors

Advanced Solid Tumor | Non Small Cell Lung Cancer Metastatic

United States, Taiwan, Germany, Singapore, Spain
Iovance Biotherapeutics, Inc.

No longer available

Expanded Access Program of Lifileucel (LN-144) in Patients With Unresectable or Metastatic Melanoma

Metastatic Melanoma | Unresectable Melanoma

United States
Iovance Biotherapeutics, Inc.

Active, not recruiting

Study of Lifileucel (LN-144), Autologous Tumor Infiltrating Lymphocytes, in the Treatment of Patients With Metastatic Melanoma (LN-144)

Metastatic Melanoma

United States, Spain, Germany, United Kingdom, France, Hungary, Italy, Switzerland
Fujian Akeylink Biotechnology Co., Ltd.

Recruiting

A Randomized, Double-blind, Placebo-controlled Phase IIa Clinical Study to Evaluate the Safety and Efficacy of GST-HG131 Tablets in Patients With Chronic Hepatitis B

Chronic Hepatitis B

China
Oswaldo Cruz Foundation
Ministry of Health, Brazil

Terminated

Probiotics for the Prevention of Premature Birth and Neonatal Related Morbidity

Sepsis | Premature Birth | Bronchopulmonary Dysplasia | Bacterial Vaginosis | Periventricular Leukomalacia

Brazil
Fujian Akeylink Biotechnology Co., Ltd.

Completed

Safety, Tolerability and Pharmacokinetic Characteristics Evaluation on GST-HG171 Tablets

COVID-19

China
University Hospital Heidelberg

Terminated

Gemtuzumab Ozogamicin in Induction and Glasdegib in Postremission Therapy in Patients With AML (Acute Myeloid Leukemia) (GnG)

Acute Myeloid Leukemia

Germany
University of Zurich
Life Molecular Imaging SA

Terminated

Evaluation of a New Imagingtechnologie for Thrombosis (PET-GP1_1)

Deep Vein Thrombosis | Abdominal Aortic Aneurysm

Switzerland
GlaxoSmithKline

Completed

Single Dose Escalation First Time in Human PK Study

Infections, Bacterial

Australia
Cereno Scientific AB
Abbott; Worldwide Clinical Trials

Available

Safety and Efficacy of Continued CS1 Treatment of Patients With Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

Sweden
Fujian Akeylink Biotechnology Co., Ltd.

Recruiting

Evaluation of The Safety, Efficacy and Pharmacokinetic Characteristics of GST-HG141 Tablets

Chronic Hepatitis b

China
GlaxoSmithKline
Aeras

Completed

Study in Healthy Adults to Evaluate Gene Activation After Vaccination With GlaxoSmithKline (GSK) Biologicals' Candidate Tuberculosis (TB) Vaccine GSK 692342

Tuberculosis

Belgium
Fujian Cosunter Pharmaceutical Co. Ltd

Completed

Study on the Tolerability, Pharmacodynamics and Pharmacokinetics of GST-HG141 Tablets

Hepatitis B

China
University of Tennessee Graduate School of Medicine

Active, not recruiting

Repeat PET/CT Imaging of Patients With Amyloid 124I-AT-01 to Measure Changes in Organ-specific Amyloid Load

Systemic Amyloidosis

United States
Celltrion

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of CT-G20 or CT-G11 and Food Effect of CT-G20 in Human Participants

Healthy

Korea, Republic of
GlaxoSmithKline

Completed

A Study to Assess the Relative Bioavailability of Four New Formulations of GSK1605786 in Healthy Subjects

Crohn's Disease

United States
VegaVect, Inc.
National Eye Institute (NEI)

Active, not recruiting

Study of RS1 Ocular Gene Transfer for X-linked Retinoschisis

Retinoschisis | X-Linked

United States
Neuromod Devices Ltd.
University Hospital Regensburg

Completed

Treatment Evaluation of Neuromodulation for Tinnitus (TENT-A)

Tinnitus

Germany, Ireland
CardiacSense Ltd.

Completed

Performance and Efficacy of the CardiacSense1 for Detection of Atrial Fibrillation

Atrium; Fibrillation

Israel
Johannes Gutenberg University Mainz
Deutsche Rentenversicherung; Koblenz University of Applied Science

Completed

Implementation of the Internet-based Aftercare Program 'GSA-Online Plus'

Implementation

Germany
National Cerebral and Cardiovascular Center
Juntendo University; Kyoto University; Kobe City General Hospital

Completed

Safety and Efficacy of Honeycomb Microporous Covered Stents (NCVC-CS1) for the Treatment of Intracranial Aneurysms (NCVC-CS1_UAN)

Intracranial Aneurysm

Japan
Fudan University

Unknown

Treatment of Cerebral Radiation Necrosis With GM1, a Prospective Study

MRI | Nasopharyngeal Carcinoma | Radiotherapy | Cerebral Radiation Necrosis

China
Memorial Sloan Kettering Cancer Center
Iovance Biotherapeutics, Inc.

Active, not recruiting

A Study of LN-144 in People With Metastatic Melanoma to the Brain

Metastatic Melanoma

United States
Philips Clinical & Medical Affairs Global

Recruiting

HeartStart HS1 Defibrillator* Event Registry

Sudden Cardiac Arrest

United States
Cardiaccs AS
European Commission

Enrolling by invitation

Temporary Epicardial Pace Wire With Integrated Sensor for Continuous Postoperative Monitoring of Myocardial Function

Cardiac Disease | Myocardial Dysfunction

Norway
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety and Pharmacokinetics of a Single Dose of GSI-953

Healthy

Japan
University of Edinburgh
British Heart Foundation; Life Molecular Imaging SA

Completed

18F-GP1 PET-CT to Detect Bioprosthetic Aortic Valve Thrombosis

Aortic Valve Disease | Thrombosis Cardiac

United Kingdom
University of Oklahoma

Terminated

The Sukhshanti Study: Effect of a Sanitation Intervention on Women's Health

Stress, Psychological

India
Drexel University

Completed

Project BITE: Binge Intervention Target Effectiveness

Binge-Eating Disorder

United States
Zhejiang University
Yake Biotechnology Ltd.

Not yet recruiting

A Study of CS1-targeted CAR-T Cells Therapy for Relapsed Multiple Myeloma After BCMA CAR-T Cells Therapy

Relapse Multiple Myeloma

China
GlaxoSmithKline

Completed

Study to Evaluate the Impact of Reactogenicity on Quality of Life (QoL), After Administration of GlaxoSmithKline (GSK) Biologicals' Candidate Herpes Zoster Subunit (HZ/su) Vaccine (GSK1437173A) in Adults ≥ 50 Years of Age

Herpes Zoster

United States
GlaxoSmithKline

Terminated

Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine in Adults With TB Disease

Tuberculosis

Taiwan, Estonia
GlaxoSmithKline

Completed

Clinical Study of the Immunogenicity of GSK Biologicals' Influenza Vaccine GSK2186877A in People Aged 65 Years or Older

Influenza

Spain, United States

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