Search clinical trials for: Glutaminase Inhibitor CB-839
Total 300 results
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Calithera Biosciences, IncCompletedHealthy VolunteersUnited States
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National Cancer Institute (NCI)RecruitingMetastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Brain | Leptomeningeal Neoplasm | Recurrent Lung Non-Small Cell CarcinomaUnited States
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Calithera Biosciences, IncCompletedAcute Myeloid Leukemia (AML) | Acute Lymphocytic Leukemia (ALL)United States
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Calithera Biosciences, IncCompletedRenal Cell Carcinoma | Non Small Cell Lung Cancer | Mesothelioma | Solid Tumors | Triple-Negative Breast Cancer | Fumarate Hydratase (FH)-Deficient Tumors | Succinate Dehydrogenase (SDH)-Deficient Gastrointestinal Stromal Tumors (GIST) | Succinate Dehydrogenase (SDH)-Deficient Non-gastrointestinal... and other conditionsUnited States
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Tallikut Pharmaceuticals, Inc.Completed
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)CompletedChronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | High Risk Myelodysplastic Syndrome | Acute Myeloid Leukemia With Multilineage Dysplasia | Blasts 20-30 Percent of Bone Marrow Nucleated Cells | Blasts 20-30 Percent of Peripheral Blood White Cells | IPSS Risk Category Intermediate-2United States
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University of Alabama at BirminghamTerminatedOvarian Cancer | Resistant BRCA Wild-Type Ovarian CancerUnited States
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Vanderbilt-Ingram Cancer CenterNational Cancer Institute (NCI); Calithera Biosciences, IncActive, not recruitingMetastatic Colorectal Cancer | Colorectal Cancer | RAS Wild Type Colorectal Cancer | Refractory Colorectal CancerUnited States
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Calithera Biosciences, IncCompletedMetastatic Renal Cell Carcinoma | Advanced Renal Cell CarcinomaUnited States, United Kingdom, Australia, France, Italy, Germany, Spain, New Zealand
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Calithera Biosciences, IncCompletedMultiple Myeloma | Non-Hodgkin's Lymphoma (NHL) | Waldenstrom's Macroglobulinemia (WM) | Other B-cell NHL Subtypes, Including WM | T-cell NHLUnited States
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Massachusetts General HospitalPfizer; Prostate Cancer Foundation; Calithera Biosciences, IncNot yet recruiting
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David BajorActive, not recruitingCB-839 + Capecitabine in Solid Tumors and Fluoropyrimidine Resistant PIK3CA Mutant Colorectal CancerColorectal Cancer | Rectal Cancer | Solid Tumor | Colon CancerUnited States
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Calithera Biosciences, IncCompletedNSCLC | Solid Tumors | KRAS Gene Mutation | CRCUnited States
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National Cancer Institute (NCI)Active, not recruitingAstrocytoma, IDH-Mutant, Grade 2 | Astrocytoma, IDH-Mutant, Grade 3United States
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Calithera Biosciences, IncTerminatedMelanoma | Non-small Cell Lung Cancer (NSCLC) | Clear Cell Renal Cell Carcinoma (ccRCC)United States
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Washington University School of MedicineNational Cancer Institute (NCI); Calithera Biosciences, IncNot yet recruitingCervical Cancer | Cervix Cancer | Advanced Cervical Carcinoma | Cancer of the CervixUnited States
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National Cancer Institute (NCI)WithdrawnLocally Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Aggressive Non-Hodgkin Lymphoma | Indolent Non-Hodgkin LymphomaUnited States
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Calithera Biosciences, IncCompletedClear Cell Renal Cell CarcinomaUnited States
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Calithera Biosciences, IncTerminatedClear Cell Renal Cell Carcinoma | Colorectal Cancer | Solid Tumor | CRC | TNBC - Triple-Negative Breast Cancer | ccRCC | RCCUnited States
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Calithera Biosciences, IncCompletedTriple Negative Breast Cancer | TNBC - Triple-Negative Breast CancerUnited States
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National Cancer Institute (NCI)RecruitingMetastatic Lung Non-Small Cell Carcinoma | Stage IV Lung Cancer AJCC v8 | Advanced Lung Non-Small Cell CarcinomaUnited States
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National Cancer Institute (NCI)Active, not recruitingAdvanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | NF1 Mutation Positive Malignant Peripheral Nerve Sheath TumorUnited States
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Calithera Biosciences, IncNovotech (Australia) Pty LimitedCompleted
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National Cancer Institute (NCI)Active, not recruitingRefractory Multiple Myeloma | Recurrent Multiple MyelomaUnited States
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University of BernUniversity of Zurich; Swiss National Science Foundation; Centre Hospitalier Universitaire... and other collaboratorsNot yet recruitingReflux Disease | Inappropriate Prescribing | Proton Pump InhibitorsSwitzerland
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Vanderbilt-Ingram Cancer CenterTerminatedRecurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal CancerUnited States
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Glenn J. HannaAdenoid Cystic Carcinoma Research Foundation; Cellestia Biotech AGRecruitingAdenoid Cystic Carcinoma | Metastatic Adenoid Cystic Carcinoma | Recurrent Adenoid Cystic CarcinomaUnited States
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Memorial Sloan Kettering Cancer CenterTerminatedSarcoma | Neuroblastoma | CNS CancerUnited States
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Air Force Military Medical University, ChinaNot yet recruitingMucositis OralChina
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AbbottTerminatedLiver Diseases | Digestive System Diseases | Neoplasms | Neoplasms by Histologic Type | Neoplasms by Site | Adenocarcinoma | Carcinoma | Neoplasms, Glandular and Epithelial | Digestive System Neoplasms | Carcinoma, Hepatocellular | Liver Neoplasms | Hepatocellular Carcinoma Non-resectable | Hepatocellular Carcinoma...United States, Argentina, Australia, Austria, Belgium, Canada, Chile, China, Czech Republic, Denmark, Egypt, France, Germany, Greece, Hong Kong, Italy, Japan, Korea, Republic of, Malaysia, Mexico, Netherlands, New Zealand, Norway, Puerto... and more
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Stanford UniversityAstraZeneca; American Society of Clinical OncologyCompletedHead and Neck Cancer | Carcinoma, Squamous CellUnited States
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AbbottCompletedSolid TumorsUnited States
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Institut de Recherches Internationales ServierMerck Sharp & Dohme LLCRecruiting
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MedSIRCellestia Biotech AGTerminated
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National Cancer Institute (NCI)CompletedInsular Thyroid Cancer | Recurrent Thyroid Cancer | Stage IIIB Non-small Cell Lung Cancer | Anaplastic Thyroid Cancer | Tongue Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous... and other conditionsUnited States
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AbbottGenentech, Inc.Withdrawn
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National Cancer Institute (NCI)Gynecologic Oncology GroupCompletedRecurrent Uterine Corpus CarcinomaUnited States
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Calithera Biosciences, IncTerminatedNon-Small Cell Lung Cancer | Non-squamous Non-small-cell Lung Cancer | Non-Squamous Non-Small Cell Neoplasm of Lung | KEAP1 Gene Mutation | NRF2 Gene Mutation | NFE2L2 Gene MutationUnited States
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National Cancer Institute (NCI)CompletedRecurrent Malignant Mesothelioma | Advanced Malignant Mesothelioma | Epithelial Mesothelioma | Sarcomatous MesotheliomaUnited States
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National Cancer Institute (NCI)CompletedGastrinoma | Glucagonoma | Insulinoma | Metastatic Gastrointestinal Carcinoid Tumor | Pancreatic Polypeptide Tumor | Recurrent Gastrointestinal Carcinoid Tumor | Recurrent Islet Cell Carcinoma | Somatostatinoma | WDHA SyndromeUnited States
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University of ChicagoCompletedHead and Neck CancerUnited States
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Millennium Pharmaceuticals, Inc.CompletedAdvanced Nonhematologic MalignanciesUnited States, Spain, United Kingdom
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National Cancer Institute (NCI)CompletedStage IIIB Non-small Cell Lung Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer | Bronchoalveolar Cell Lung CancerUnited States
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National Cancer Institute (NCI)CompletedStage IIIA Non-small Cell Lung Cancer | Squamous Cell Lung Cancer | Adenocarcinoma of the Lung | Bronchoalveolar Cell Lung Cancer | Large Cell Lung Cancer | Adenosquamous Cell Lung Cancer | Stage IB Non-small Cell Lung Cancer | Stage IIA Non-small Cell Lung Cancer | Stage IIB Non-small Cell Lung CancerCanada
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National Cancer Institute (NCI)CompletedAdvanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Adult Primary Hepatocellular CarcinomaUnited States
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Vanderbilt-Ingram Cancer CenterNational Cancer Institute (NCI)TerminatedBreast CancerUnited States
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H. Lee Moffitt Cancer Center and Research InstituteAstraZenecaCompletedGastric Cancer | Esophageal CancerUnited States, Puerto Rico
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Dana-Farber Cancer InstituteMassachusetts General Hospital; Beth Israel Deaconess Medical Center; Brigham...CompletedMetastatic Pancreatic CarcinomaUnited States
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OBI Pharma, IncRecruiting