Search clinical trials for: IL-12 DNA (formulated with bupivacaine)

Total 28 results

Wyeth is now a wholly owned subsidiary of Pfizer

Terminated

Study Evaluating Vaccine in Adults With HIV

HIV Infections

Germany, United States, Sweden
National Institute of Allergy and Infectious Diseases...

Completed

Safety of and Immune Response to an HIV Preventive Vaccine (HIV-1 Gag DNA Alone or With IL-15 DNA) Given With or Without 2 Different Booster Vaccinations in HIV Uninfected Adults

HIV Infections

United States, Brazil
Imperial College London
Bill and Melinda Gates Foundation

Completed

Optimising DNA Vaccinations in Healthy Volunteers (DNAVAC001)

HIV-1-infection
National Institute of Allergy and Infectious Diseases...

Completed

Safety of and Immune Response to the PENNVAX-B DNA Vaccine With and Without IL-12 in HIV-uninfected Adults

HIV Infections

United States
H. Lee Moffitt Cancer Center and Research Institute
National Gene Vector Laboratory

Completed

Phase I Trial of Intratumoral pIL-12 Electroporation in Malignant Melanoma

Malignant Melanoma

United States
National Institute of Allergy and Infectious Diseases...

Completed

Safety and Immunogenicity of pDNA Vaccines Expressing HIV M Group p24^Gag Conserved Elements and/or p55^Gag, Administered With IL-12 pDNA (HVTN119)

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Safety of and Immune Response to an Investigational HIV-1 Vaccine With or Without Interleukin-12 (IL-12) in HIV-1 Infected Adults

HIV Infections

United States
University of Chicago

Completed

Study of MAGE-3/Melan-A/gp 100/NA17 and rhIL-12 With/Out Low Dose IL-2 in Metastatic Melanoma

Metastatic Melanoma

United States
OncoSec Medical Incorporated

Terminated

Phase II Intratumoral IL12 Plasmid Electroporation in Cutaneous Lymphoma (CTCL)

Mycosis Fungoides (MF) | Cutaneous T Cell Lymphomas (CTCL)

United States
OncoSec Medical Incorporated
National Cancer Institute (NCI)

Completed

IL-12 Gene and in Vivo Electroporation-Mediated Plasmid DNA Vaccine Therapy in Patients With Merkel Cell Cancer (MCC)

Merkel Cell Carcinoma

United States
OncoSec Medical Incorporated

Terminated

Trial of pIL-12 Electroporation in Squamous Cell Carcinoma of the Head and Neck (IL12HNSCC)

Head and Neck Squamous Cell Carcinoma

United States
National Institute of Allergy and Infectious Diseases...
Auro Vaccines LLC

Completed

Therapeutic Vaccine for HIV

HIV | Therapeutic Vaccine

United States
National Institute of Allergy and Infectious Diseases...

Completed

Study of an HIV Preventive Vaccine Given With or Without an Adjuvant in HIV Uninfected Adults

HIV Infections

United States, Thailand
OncoSec Medical Incorporated

Completed

Trial of pIL-12 Electroporation Malignant Melanoma (IL-12MEL)

Melanoma

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

EGEN-001 and Pegylated Liposomal Doxorubicin Hydrochloride in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Ovarian Clear Cell Cystadenocarcinoma | Ovarian Endometrioid Adenocarcinoma | Ovarian Seromucinous Carcinoma | Ovarian Serous Cystadenocarcinoma | Ovarian Undifferentiated Carcinoma

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Immunogenicity of PENNVAX®-GP DNA Vaccine and IL-12 Plasmid, Delivered Via Intradermal or Intramuscular Electroporation in Healthy, HIV-Uninfected Adults

HIV Infections

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

EGEN-001 in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer

Recurrent Ovarian Carcinoma | Fallopian Tube Carcinoma | Primary Peritoneal Carcinoma

United States
National Institute of Allergy and Infectious Diseases...
Department of Health and Human Services; HIV Vaccine Trials Network; Inovio Pharmaceuticals and other collaborators

Active, not recruiting

Clinical Trial to Evaluate the Safety and Immunogenicity of Synthetic DNAs Encoding NP-GT8 and IL-12, With or Without a TLR-agonist-Adjuvanted HIV Env Trimer 4571 Boost, in Adults Without HIV

HIV Infections

United States, South Africa
Steven Deeks
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Completed

Therapeutic Vaccination in Treated HIV Disease

HIV-1-infection

United States
Chase Heaton, MD
Incyte Corporation; OncoSec Medical Incorporated

Terminated

Optimizing Antitumor Immunity Using Plasmid Electroporation, Pembrolizumab, and Epacadostat

Recurrent Head and Neck Squamous Cell Carcinoma | Metastatic Head and Neck Squamous Cell Carcinoma | Unresectable Head and Neck Squamous Cell Carcinoma

United States
Washington University School of Medicine
The Foundation for Barnes-Jewish Hospital; Geneos Therapeutics

Active, not recruiting

Neoantigen-based Personalized DNA Vaccine in Patients With Newly Diagnosed, Unmethylated Glioblastoma

Glioblastoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

DNA Plasmid-encoding Interleukin-12/HPV DNA Plasmids Therapeutic Vaccine INO-3112 and Durvalumab in Treating Patients With Recurrent or Metastatic Human Papillomavirus Associated Cancers

Stage IV Anal Cancer AJCC v8 | Recurrent Cervical Carcinoma | Metastatic Malignant Neoplasm | Stage IV Penile Cancer AJCC v8 | Recurrent Malignant Neoplasm | Refractory Malignant Neoplasm | Stage IV Cervical Cancer AJCC v8 | Stage IVA Cervical Cancer AJCC v8 | Stage IVB Cervical Cancer AJCC v8 | Stage... and other conditions

United States
Bozyaka Training and Research Hospital

Completed

Effects of Preoperative Fasting on ECG and Vital Parameters

Ischemia | Intraoperative Complications | Fasting

Turkey
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety of and Immune Response to HIV-MAG DNA Vaccine With or Without Plasmid IL-12 Adjuvant Delivered Intramuscularly Via Electroporation Followed by VSV-gag HIV Vaccine Boost in Healthy, HIV-Uninfected Adults

HIV Infections

United States
Institut National de la Santé Et de la Recherche...

Terminated

Effect of Docosahexaenoic Acid (DHA)-Enriched Human Milk in Premature Newborns (DHARMA)

Premature

France
Zuyderland Medisch Centrum
AtriCure, Inc.

Recruiting

Intercostal Nerve Cryoablation Versus Epidural Analgesia for Nuss Repair of Pectus Excavatum (ICE)

Funnel Chest | Pectus Excavatum

Netherlands
Fred Hutchinson Cancer Center

Recruiting

Ustekinumab for the Prevention of Acute Graft-versus-Host Disease After Unrelated Donor Hematopoietic Cell Transplant

Hematopoietic and Lymphoid System Neoplasm | Hematologic and Lymphocytic Disorder

United States
Centre Georges Francois Leclerc

Recruiting

Evaluation and Modeling of the Effect of G-CSF on the Evolution of Polynuclear Neutrophils During Dense Dose Epirubicin-Cyclophosphamide Regeneration (EMEG-ECDD)

Localized Breast Cancer

France

Search clinical trials for: IL-12 DNA (formulated with bupivacaine)

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