Search clinical trials for: ISIS 301012

Total 394 results

Ionis Pharmaceuticals, Inc.

Completed

Safety, Tolerability, and Efficacy of ISIS-PTP1BRx in Type 2 Diabetes

Type 2 Diabetes Mellitus | Obese

Argentina, Canada, South Africa
Akcea Therapeutics
Ionis Pharmaceuticals, Inc.

Completed

Phase 2 Study of ISIS 681257 (AKCEA-APO(a)-LRx) in Participants With Hyperlipoproteinemia(a) and Cardiovascular Disease

Cardiovascular Disease | Elevated Lipoprotein(a)

United States, Canada, Denmark, Germany, Netherlands
University of Alabama at Birmingham
National Institutes of Health (NIH)

Completed

Nasal Potential Studies Utilizing Cystic Fibrosis Transmembrane Regulator (CFTR) Modulators

Cystic Fibrosis

United States
INTRuST, Post-Traumatic Stress Disorder - Traumatic...
U.S. Army Medical Research and Development Command

Completed

CONcussion Treatment After Combat Trauma (CONTACT) (CONTACT)

Traumatic Brain Injury

United States
Fondation Ildys
Lille Catholic University

Completed

Effects of Electrostimulation on Glycemic Control in Obesity (ElectrOBA)

Obesity Adult Onset

France
Zhen-Yu Ding

Recruiting

DC Combined With ICIs in the Treatment of Advanced Lung Cancer Resistant to ICIs

Lung Cancer

China
Emory University
National Institute on Minority Health and Health Disparities (NIMHD)

Completed

Better Together Study

Type 2 Diabetes

United States
First Affiliated Hospital of Wenzhou Medical University

Completed

Acute Kidney Injury in Cancer Patients Receiving Anti-Vascular Endothelial Growth Factor Monoclonal Antibody vs Immune Checkpoint Inhibitors

AKI Incidence of Cancer Patients Receiving AntiVEGF or ICIs

China
Medical University of Vienna

Completed

TELEMS: Feasibility of Remote Patient Visits in MS (TELEMSRCT)

Multiple Sclerosis

Austria
University of California, San Diego

Recruiting

Effect of Anti-inflammatory (ITIS) Diet in Knee Osteoarthritis

Osteoarthritis, Knee

United States
Microbicide Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Assessment of ASPIRE and HOPE Adherence

HIV Prevention

Zimbabwe, Malawi, South Africa, Uganda
Virginia Commonwealth University
Georgetown University

Recruiting

Improving Communication and Adherence in Black Breast Cancer Survivors (Sisters Informing Sisters) (SIS)

Breast Cancer

United States
Hamilton Health Sciences Corporation
Canadian Institutes of Health Research (CIHR); DePuy Orthopaedics; London Health...

Unknown

An RCT to Compare the Outcomes of Patients With Large Rotator Cuff Repair That Undergo Repair With or Without SIS

Rotator Cuff Tear

Canada
Ionis Pharmaceuticals, Inc.

Completed

Addition of ISIS 14803 to Therapy With Peginterferon and Ribavirin for Chronic Hepatitis C (HCV) Patients Not Responding Adequately to the Two Drugs

Hepatitis C, Chronic

United States
Shanghai University of Traditional Chinese Medicine
Fudan University; Shanghai Zhongshan Hospital; Ruijin Hospital; Shanghai Chest... and other collaborators

Not yet recruiting

Clinical Study on the Prevention of Driver Gene Negative II-IIIa Lung Cancer Recurrence and Metastasis by Staged Chinese Herbal Medicine Combined With Chemotherapy and Immune Checkpoint Inhibitors

Lung Cancer

China
Qilu Pharmaceutical Co., Ltd.

Completed

Efficacy and Safety of QL1012 in Women for Assisted Reproductive Treatment

Infertility

China
State University of New York - Upstate Medical...

Not yet recruiting

Zip IIS vs Standard Closure in Total Hip Arthroplasty

Total Hip Arthroplasy
University of California, San Diego

Completed

Effect of Anti-inflammatory (ITIS) Diet in Rheumatoid Arthritis

Osteoarthritis | Rheumatoid Arthritis

United States
Wake Forest University Health Sciences
Foundation for Female Health Awareness

Completed

Retropubic vs. Single-Incision Mid-Urethral Sling for Stress Urinary Incontinence

Stress Urinary Incontinence | Pelvic Floor Disorders

United States
Cairo University

Completed

Ultrasound Based Study For Niche Development In The Uterine Cesarean Section Scar

Cesarean Section; Dehiscence

Egypt
Changzhou Second People's Hospital affiliated with...

Recruiting

Sutureless Intrascleral Intraocular Lens Fixation and Modified Iris Cerclage Pupilloplasty

Aphakia | Mydriasis

China
Zhongshan Ophthalmic Center, Sun Yat-sen University

Unknown

Predicting the Effect of Laser Peripheral Iridotomy

Glaucoma

China
University of Maryland, Baltimore

Completed

BBOT: Bacterial Burden in Ortho Trauma Procedures

Orthopaedic Trauma Infections

United States
National Cancer Institute (NCI)

Completed

ISIS 183750 With Irinotecan for Advanced Solid Tumors or Colorectal Cancer

Colorectal Neoplasms | Colorectal Tumors | Colorectal Carcinoma

United States
Cook Group Incorporated

Completed

Cook Micronized Small Intestinal Submucosa (SIS) for Critical Limb Ischemia

Ischemia | Peripheral Arterial Disease | Peripheral Vascular Diseases

Canada
MiNK Therapeutics

Completed

A Study Investigating agenT-797 in Participants With Relapsed/Refractory Solid Tumors

Tumor, Solid

United States
Northwell Health
Mayo Clinic; NinePoint Medical

Completed

Volumetric Laser Endomicroscopy With Intelligent Real-time Image Segmentation (IRIS)

Barrett's Esophagus Without Dysplasia | Barrett's Esophagus With Dysplasia | Barrett's Esophagus With Low Grade Dysplasia | Barrett's Esophagus With High Grade Dysplasia | Barrett's Esophagus With Dysplasia, Unspecified

United States
Albert Einstein College of Medicine
National Cancer Institute (NCI)

Completed

SGN-00101 Immunotherapy in Treating Patients With Grade III Cervical Intraepithelial Neoplasia

Cervical Cancer | Precancerous Condition

United States
Sun Yat-sen University

Recruiting

Observation Study of Sequential Regorafenib Plus ICIs After HAIC for Advanced Hepatocellular Carcinoma

Hepatocellular Carcinoma

China
Acotec Scientific Co., Ltd

Completed

Effectiveness and Safety Study of Peripheral Balloon Dilatation Catheter in Percutaneous Transluminal Angioplasty(PTA) Procedure

Peripheral Arterial Disease

China
Massachusetts General Hospital

Completed

A Proof-of-concept RCT of Version 3.0 of the Smoking Cessation Smartphone App "Smiling Instead of Smoking" (SiS)

Nondaily Smoking

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); AstraZeneca

Active, not recruiting

Danvatirsen and Durvalumab in Treating Patients With Advanced and Refractory Pancreatic, Non-Small Cell Lung Cancer, and Mismatch Repair Deficient Colorectal Cancer

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Refractory Pancreatic Carcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Lung Non-Small Cell Carcinoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC... and other conditions

United States
DePuy International

Completed

Pilot Study to Evaluate the Restore Orthobiologic Implant in Rotator Cuff Tear Repair

Arm Injuries

United Kingdom, Belgium
University of Calgary
Alberta Health services; Cook Group Incorporated

Completed

Trial of Small Intestine Submucosa (SIS) Mesh for Anterior Repair: A Pilot Study (Anterior SIS)

Anterior Pelvic Organ Prolapse

Canada
Shaaban Elwan

Completed

Subscleral Trabeculectomy With Iris Incarceration in Buphthalmous

Iris Incarceration

Egypt
Flamingo Therapeutics NV

Recruiting

Activity and Safety of Danvatirsen and Pembrolizumab in HNSCC (PEMDA-HN)

HNSCC

United States, Korea, Republic of
Innolake Biopharm

Not yet recruiting

A Study of the ILB-3101 in Patients With Advanced Solid Tumors

Advanced Solid Tumor
Hoffmann-La Roche

Active, not recruiting

RVT-3101 for the Treatment of Moderate to Severe Active Crohn's Disease

Crohn Disease

United States, France, Poland, Hungary, Spain
Shanghai HyaMab Biotech Co.,Ltd.

Completed

HY-0102 Monotherapy in Patients With Locally Advanced/Metastatic Solid Tumours

Locally Advanced/Metastatic Solid Tumors

United States
Coloplast A/S

Completed

The Altis® Single Incision Sling System for Female Stress Urinary Incontinence Study

Stress Urinary Incontinence

United States, Canada
Wageningen University
Top Institute Food and Nutrition

Completed

Study on the Effects of Epicatechin and Quercetin Supplementation on Vascular Function and Blood Pressure (FLAVO)

Hypertension | Endothelial Dysfunction

Netherlands
University of Alabama at Birmingham
Stanford University; Cook Group Incorporated

Completed

Nasal Septal Flap for Donor Site Reconstruction

Nasal Septum Perforation
IRCCS Centro Neurolesi "Bonino-Pulejo"

Recruiting

Intensive Neurowave Emotional Stimulation (INES) (INES_ABI)

Disorders of Consciousness

Italy
Merck Sharp & Dohme LLC

Completed

A Pharmacokinetic Study of MK-3102 in Participants With Impaired Hepatic Function (MK-3102-031)

Diabetes Mellitus, Type 2
Dolorgiet GmbH & Co. KG
d.s.h. statistical services GmbH; CenTrial GmbH

Completed

Study Whose Purpose is to Find an Optimal Dose for the Treatment With AK 3012 in Patients With Actinic Keratosis

Actinic Keratosis Olsen Grade I/II

Germany
Azafaros A.G.

Active, not recruiting

Phase 2 Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral AZ-3102 in Patients With GM2 Gangliosidosis or Niemann-Pick Type C Disease (RAINBOW)

Niemann-Pick Disease, Type C | GM2 Gangliosidosis

Brazil
Cutia Therapeutics（Wuxi）Co.,Ltd

Completed

A Phase 3 Clinical Study Patients With Androgenetic Alopecia (AGA)

AGA

China
University of California, Los Angeles

Completed

Clinical Evaluation of Morcher Artificial Iris Diaphragms

Aniridia | Iris; Deformity

United States
Rigshospitalet, Denmark

Completed

18F-ASIS PET/CT Imaging of Tissue Factor Expression In Patients With Primary and Metastastic Cancer

Breast Cancer | Pancreatic Cancer | Ovarian Cancer | Lung Cancer | Cervix Cancer

Denmark
Advanced BioDesign

Active, not recruiting

First-in-human Study Aiming to Characterize the Safety, Tolerability, Pharmacokinetic and Preliminary Signs of Activity of ABD-3001 in Refractory or Relapsed AML and High Risk MDS Adult Patients (ODYSSEY)

Myelodysplastic Syndromes | Acute Myeloid Leukemia, Adult

France

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