Search clinical trials for: IV. PPI

Total 5032 results

Takeda

Completed

Bioavailability and Pharmacokinetics of Vedolizumab in Healthy Participants Following Single Subcutaneous Administration

Healthy

United Kingdom
Odense University Hospital

Unknown

Doppler-guided Endoscopic Treatment in Peptic Ulcer Bleeding

Peptic Ulcer Bleeding

Denmark
Uayporn Kaosombatwattana

Completed

Efficacy of Vonoprazan Versus Intravenous Proton Pump Inhibitors for Prevention of Rebleeding in High Risk Peptic Ulcers Bleeding After Successful Endoscopic Hemostasis

Peptic Ulcer With Haemorrhage

Thailand
Presidio Pharmaceuticals, Inc.

Completed

Phase 1 Study of Relative Bioavailability of PPI-668 New Tablet Versus Capsule Formulations

Pharmacokinetic Assessments in Healthy Volunteers

United States
Presidio Pharmaceuticals, Inc.

Completed

Phase 1 Study of Relative Bioavailability of PPI-668 Tablet and Capsule Formulations

Pharmacokinetic Assessments in Healthy Volunteers

United States
Rigshospitalet, Denmark

Active, not recruiting

DANish Study of Optimal Acute Treatment of Patients With ST-elevation Myocardial Infarction (DANAMI-3)

ST Segment Elevation Myocardial Infarction

Denmark
Shire

Completed

Selective 5-HT4 Receptor Agonist and Proton Pump Inhibitor (PPI) in Subjects With Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease

United States, Czechia, Germany, Latvia, Poland, Romania
University of Southern California

Withdrawn

PPI Versus Placebo in Severe Functional Heartburn

GERD

United States
Al-Azhar University

Not yet recruiting

Minimally Invasive Scrotal Incision for Penile Prosthesis Implantation, Novel Technique. (PPI)

Penile Prosthesis Infection | Penile Prosthesis; Complications, Infection or Inflammation
PRAECIS Pharmaceuticals Inc.

Terminated

Safety/Tolerance Study of PPI-2458 in Subjects With Non-Hodgkin's Lymphoma and Solid Tumors

Solid Tumors | Non-Hodgkin's Lymphoma,

United States
University College, London
National Institute for Cardiovascular Outcomes Research; British Cardiovascular... and other collaborators

Completed

Exploring the Volume-Outcome Relationship for PCI Procedures Undertaken in a UK Context: A NICOR Study

Percutaneous Coronary Intervention

United Kingdom
Yonsei University

Completed

Efficacy of Proton Pump Inhibitor for Chronic Cough Caused by Gastroesophageal Reflux; Double-blind, Placebo-controlled, Randomized Clinical Trial

Chronic Cough Caused by Gastroesophageal Reflux

Korea, Republic of
Braintree Laboratories

Recruiting

A Study to Evaluate the Efficacy and Safety of BLI5100 in Patients With Erosive Esophagitis

Erosive Esophagitis

United States
PRAECIS Pharmaceuticals Inc.

Completed

Safety Study of PPI-1019 in Subjects With Mild-Moderate Alzheimer's Disease

Alzheimer's Disease

United States
PRAECIS Pharmaceuticals Inc.

Completed

Safety Study of PPI-1019 in Patients With Mild-Moderate Alzheimer's Disease

Alzheimer's Disease

United States
Soonchunhyang University Hospital

Completed

Surgicel® Fibrillar for Delayed Bleeding After ESD

Malignant Neoplasm of Stomach | Benign Neoplasm of Stomach

Korea, Republic of
Centre Hospitalier Universitaire de Nice

Not yet recruiting

Inorganic Pyrophosphate Homeostasis (PPi) in Pediatric Chronic Kidney Disease (PPi-DIA)

Pyrophosphate, Fetuin A, IL1, IL6, TNFalpha, Control

France
Central Hospital, Nancy, France

Not yet recruiting

Evaluation of the "Pupillary Pain Index" in Neurological Prognosis After Cardiac Arrest (CAPPI)

Cardiac Arrest | Anoxic Brain Injury | Post-Anoxic Coma
AstraZeneca

Completed

A Clinical Trial in Healthy Volunteers and Patients With Mild Asthma to Investigate a New Medicine (AZD4604) for the Treatment of Asthma

Asthma

United Kingdom
King Chulalongkorn Memorial Hospital

Recruiting

High Dose Oral Omeprazole in High Risk UGIB

GI Bleeding

Thailand
Forest Laboratories

Completed

Safety and Efficacy Study of Ceftaroline Versus a Comparator in Pediatric Subjects With Complicated Community Acquired Pneumonia (CABP)

Infections | Pneumonia

United States, Ukraine, Argentina, Georgia
Zhongshan Ophthalmic Center, Sun Yat-sen University

Completed

Prophylactic Peripheral Iridectomy Prevents Aphakic Angle-closure Glaucoma

Congenital Cataract | Aphakic Glaucoma

China
University Hospital, Caen

Completed

Delirium Related to Proton Pump Inhibitors Use

Delirium | Hyponatremia | Proton Pump Inhibitor Adverse Reaction

France
HaEmek Medical Center, Israel

Completed

Prepulse Inhibition (PPI) of Startle Reflex in Schizophrenia Patients Related to Type of Treatment and Illness Duration

Schizophrenia | Medication Adherence | Inhibition (Psychology)

Israel
Centre Hospitalier Universitaire de Nice

Recruiting

PPI Supplementation to Fight ECtopIc Calcification in PXE (PROPHECI-PPI)

Pseudoxanthoma Elasticum

France
Minia University

Completed

Preoperative PPI in Sleeve Gastrectomy

Morbid Obesity

Egypt
National Hepatology & Tropical Medicine Research...

Recruiting

Role of Octreotide in Non Variceal Bleeding

Non-variceal Gastrointestinal Bleeding

Egypt
Centre Hospitalier Universitaire Dijon

Completed

the Impact of Paediatric Use of Proton Pump Inhibitors on the Risk of Community Acquired Infections. (UTOPIE)

Community Infections

France
Rabin Medical Center

Withdrawn

Gastric Acid Rebound Secretion Measured by Alkaline Tide

Condition Measuring Alkaline Tide and Filling Symptoms' Questionnaire After Abrupt or Gradual Step Down Cessation of PPI
Samsung Medical Center

Recruiting

Emulation of Randomized Clinical Trial in Cardiovascular Disease (RCT-BigData)

Myocardial Infarction | Coronary Artery Disease

Korea, Republic of
Yonsei University

Completed

Treatment Response of Maintenance Dose of Proton Pump Inhibitor in Patients With Nonerosive Gatroesophageal Reflux Disease

Non-erosive Gatroesophageal Reflux Disease

Korea, Republic of
Universitaire Ziekenhuizen KU Leuven

Recruiting

Primary carE PPi dEprescRibing Trial (PEPPER)

Dyspepsia | Heartburn | Reflux

Belgium
Takeda

Completed

Dose Finding Study of Vedolizumab for GvHD in Participants Undergoing Allogeneic HSCT

Allogeneic Hematopoietic Stem Cell Transplantation

United States
Duke University

Recruiting

Deprescribing Proton Pump Inhibitors to Reduce Post-TIPS Hepatic Encephalopathy

Hepatic Encephalopathy

United States
Taipei City Hospital

Not yet recruiting

TCHCCT-Zhong-Xing-Emergency-Department Ultrasound With IV Contrast in Acute Flank Pain

Acute Flank Pain

Taiwan
University of California, Davis

Completed

Casinomacropeptide and Satiety (CMP2)

Appetite Disorders | Lack of Satiety | Excess Intake of Macronutrients

United States
Prolacta Bioscience

Completed

Dietary Supplement With and Without a Probiotic

Healthy Adult Subjects

United States
Nantes University Hospital

Completed

Efficacy of a Multi-faceted Intervention to Deprescribe Proton Pump Inhibitors (PPI) in Primary Care: a Population-based, Pragmatic, Cluster-randomized Controlled Trial. (DeprescrIPP)

Proton Pump Inhibitors | Deprescription

France
EndoGastric Solutions

Completed

The EndoGastric Solutions TEMPO Trial (TEMPO)

Gastroesophageal Reflux Disease (GERD)

United States
Eli Lilly and Company

Completed

A Study of LY3316531 in Healthy Participants and in Participants With Psoriasis

Psoriasis

United States
University of Colorado, Denver
Cystic Fibrosis Foundation

Terminated

Effect of Acid Blockade on Microbiota and Inflammation in Cystic Fibrosis (CF)

Cystic Fibrosis

United States
Healthgen Biotechnology Corp.

Recruiting

Study of OsrhAAT or Placebo in Healthy Volunteers

Emphysema Secondary to Congenital AATD

United States
Kyowa Kirin Co., Ltd.

Terminated

Study of KHK 4323 in Healthy Volunteers and Subjects With Atopic Dermatitis

Atopic Dermatitis

Japan
BeyondSpring Pharmaceuticals Inc.
Covance; ICON plc

Completed

Plinabulin vs. Pegfilgrastim in Patients With Solid Tumors Receiving Docetaxel Myelosuppressive Chemotherapy Phase 3 (Protective-1)

Chemotherapy-induced Neutropenia

China, Russian Federation, United States, Ukraine
Healthgen Biotechnology Corp.

Completed

A Study of OsrHSA in Adult Healthy Male and Female Volunteers

Ascites Hepatic

United States
Eli Lilly and Company

Completed

A Study of LY3002813 in Participants With Alzheimer's Disease

Alzheimer Disease

United States, Japan
Mitsubishi Tanabe Pharma America Inc.

Completed

Relative Bioavailability and Drug-drug Interaction Study With MT-7117 and a Proton Pump Inhibitor (MT-7117 BA DDI)

Healthy Volunteer

Germany
VA Office of Research and Development
VHA Pharmacy Benefits Management Services VA Center For Medication Safety

Completed

Evaluation of the National Randomized Proton Pump Inhibitor De-prescribing (RaPPID) Program (RaPPID)

Proton Pump Inhibitors

United States
Guy's and St Thomas' NHS Foundation Trust
Takeda

Unknown

Investigation of the Faecal Loss of Vedolizumab and Its Role in Influencing Serum Drug Levels, Outcomes and Response in Ulcerative Colitis (FAVOUR)

Ulcerative Colitis

United Kingdom
Asir John Samuel
Maharishi Markendeswar University (Deemed to be University)

Recruiting

Class IV Laser Therapy on Ejection Fraction, Cardio Biomarkers and Functional Outcomes

Acute Coronary Syndrome

India

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