Search clinical trials for: Intranasal esketamine (56 mg)

Total 134 results

Janssen Pharmaceutical K.K.

Completed

A Study to Evaluate the Efficacy, Safety and Tolerability of Fixed Doses of Intranasal Esketamine in Japanese Participants With Treatment Resistant Depression

Depression

Japan
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety and Efficacy of Intranasal Esketamine in Treatment-resistant Depression (SYNAPSE)

Treatment Resistant Depressive Disorder

United States, Japan, Belgium
Janssen Research & Development, LLC

Completed

A Study of Esketamine Nasal Spray, Administered as Monotherapy, in Adult Participants With Treatment-resistant Depression

Depressive Disorder, Treatment-Resistant

United States
Janssen-Cilag International NV

Completed

A Long-term Comparison of Esketamine Nasal Spray Versus Quetiapine Extended Release, Both in Combination With a Selective Serotonin Reuptake Inhibitor/Serotonin-Norepinephrine Reuptake Inhibitor, in Participants With Treatment Resistant Major Depressive Disorder (ESCAPE-TRD)

Depressive Disorder, Major

Israel, Hungary, Korea, Republic of, Taiwan, Portugal, Turkey, Germany, Malaysia, Denmark, Bulgaria, Czechia, Belgium, Poland, Brazil, Netherlands, Argentina, Finland, Greece, South Africa, Austria, Kazakhstan, Norway, Sweden, United...
Janssen Research & Development, LLC

Completed

Crossover Study to Evaluate the Abuse Potential of Intranasal Esketamine Compared to Racemic Intravenous Ketamine in Nondependent, Recreational Drug Users

Drug Abuse

United States
Javelin Pharmaceuticals

Completed

Efficacy and Safety of Intranasal Morphine for Pain After Bunion Surgery

Hallux Valgus
Janssen Research & Development, LLC

Completed

A Mass Balance Study With a Microtracer Dose of 14C-esketamine in Healthy Male Participants

Healthy

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effects of Esketamine on Cardiac Repolarization in Healthy Participants

Healthy

Germany
Fujian Provincial Hospital

Completed

Esketamine-propofol Versus Propofol for Flexible Bronchoscopy

Postoperative Recovery

China
Zylorion Health

Withdrawn

Repeated Intranasal Esketamine Plus Almond Therapy in Participants With Treatment Resistant Depressive Disorder - 3 Month Extension Study (ZYL-730-02)

Treatment Resistant Major Depressive Disorder
Second Affiliated Hospital of Wenzhou Medical University

Recruiting

Clinical Study of Oral Midazolam Combined With Esketamine Administered Intranasally for Pediatric Preoperative Sedation

Anxiety

China
Zylorion Health

Terminated

Repeated Intranasal Esketamine Plus Almond Therapy in Patients With Treatment Resistant Depression (ZYL-730-01)

Treatment Resistant Major Depressive Disorder

Canada
Levo Therapeutics, Inc.

Completed

Phase 3 Study of Intranasal Carbetocin (LV-101) in Patients With Prader-Willi Syndrome (CARE-PWS)

Prader-Willi Syndrome

United States, Canada, Australia
Javelin Pharmaceuticals

Completed

Efficacy and Safety of Intranasal Morphine for Pain After Third Molar Extraction

Post-Operative Pain | Third Molar Extraction
Centre Hospitalier Universitaire de Charleroi
Centre Hospitalier Universitaire de Liege

Recruiting

Comparison of Ketamine and Esketamine in Patients Suffering From Fibromyalgia Syndrome. (KESK-FIQ)

Fibromyalgia

Belgium
Psych Atlanta

Completed

Intranasal Esketamine to Maintain the Antidepressant Response to IV Racemic Ketamine

Treatment Resistant Depression

United States
Guangzhou Women and Children's Medical Center

Suspended

Intranasal Ketamine With Dexmedetomidine for the Treatment of Children With Autism Spectrum Disorder

Autism Spectrum Disorder

China
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effects of a Single-Dose and Repeat-Administration of Intranasal Esketamine on On-Road Driving in Participants With Major Depressive Disorder (DriveSaFe2)

Depressive Disorder, Major

Netherlands
Emory University

Completed

Intranasal (NAS) Ketamine for Cancer Pain

Pain | Cancer

United States
University of Cincinnati

Unknown

Emergency Ketamine Treatment of Suicidal Ideation

Depression | Suicidal Ideation | Suicidal Impulses

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Efficacy, Pharmacokinetics, Safety and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression

Depressive Disorder, Treatment-Resistant

United States, China
Groupe Oncologie Radiotherapie Tete et Cou
Schering-Plough

Completed

Intravenous Versus Subcutaneous Amifostine in Prevention of Xerostomia After RT for Head and Neck Carcinomas

Head and Neck Cancer

France
Washington University School of Medicine

Completed

Study of Amifostine and IMRT for Protecting Salivary Glands in Head and Neck Cancer

Head and Neck Cancer
Xuanhan County People's Hospital

Completed

Postoperative Analgesic Effect of Esketamine

Analgesia | Gynecological; Surgery (Previous), Affecting Fetus or Newborn, Due to Obstructed Labor

China
University of Oklahoma

Recruiting

IN Midazolam vs IN Dexmedetomidine vs IN Ketamine During Minimal Procedures in Pediatric ED

Anxiety | Laceration of Skin | Discharge Time

United States
Kythera Biopharmaceuticals

Completed

Safety Study of Deoxycholic Acid for the Reduction of Localized Subcutaneous Fat in the Submental Area in Subjects 65 to 75 Years of Age

Efficacy | Safety | Moderate to Severe Convexity of Submental Fat

United States
Eye & ENT Hospital of Fudan University

Recruiting

Comparison of Esketamine-Propofol and Fentanyl-Propofol

Hemodynamics

China
Michigan State University

Completed

Safety and Efficacy of Combining Intranasal Insulin & Acute Exercise

Exercise | Insulin

United States
Ullevaal University Hospital
University of Oslo

Completed

Ketamine on Acute Pain in Females and Males

Tooth, Impacted | Mouth and Tooth Diseases

Norway
Wuhan Union Hospital, China

Withdrawn

Prophylactic Effects of Esketamine in Surgical Patients

Surgical Injury

China
Grace Lim, MD, MS
National Institute of Mental Health (NIMH)

Recruiting

Ketamine Tolerated Dose for Postpartum Depression and Pain After Cesarean Delivery

Pain, Postoperative | Depression, Postpartum

United States
University of Tennessee Health Science Center

Completed

IN Ketamine Vs IN Midazolam and Fentanyl for Abscess I&D

Pain | Abscess

United States
Danish Head and Neck Cancer Group

Completed

DAHANCA 28A: Phase I/II Study on Accelerated, Hyperfractionated Radiotherapy With Concomitant Cisplatin and Nimorazole

HNSCC,Larynx, Pharynx and Oral Cavity

Denmark
New York State Psychiatric Institute

Terminated

Randomized Controlled Trial of Intranasal Ketamine vs. Intranasal Midazolam in Individuals With OCD

Obsessive-Compulsive Disorder

United States
Assiut University

Completed

Comparing Three Different Doses of Intrathecal Ketamine

Ketamine Causing Adverse Effects in Therapeutic Use

Egypt
Kaplan Medical Center

Unknown

Nasal Ketamine for Minor Procedures in Children

Pain
Boehringer Ingelheim

Completed

BIBF 1120 + Carboplatin/Pegylated Liposomal Doxorubicin (PLD) in Patients With Advanced Ovarian Cancer, Fallopian Tube Carcinoma or Primary Peritoneal Cancer

Ovarian Neoplasms | Peritoneal Neoplasms

Spain
Lotus Clinical Research, LLC
iX Biopharma Ltd.

Completed

A Study to Assess the Analgesic Properties of a Sublingual Wafer Formulation of Ketamine Following Third Molar Extraction

Pain

United States
Rupert Lanzenberger

Completed

Investigation of Intranasal Ketamine Related Changes in Attentional Brain Networks With Functional and Structural MRI

Ketamine Treatment

Austria
Antonios Likourezos

Completed

Nebulized Sub-dissociative Dose Ketamine for Treating Pain

Pain

United States
University of Alabama at Birmingham

Terminated

Intranasal Versus Intravenous Ketamine for Procedural Sedation in Children With Non-operative Fractures

Trauma | Fractures, Closed | Ketamine | Children, Only | Deep Sedation

United States
Janssen-Cilag International NV

Withdrawn

A Study of Esketamine Nasal Spray Plus a New Standard-of-care Oral Antidepressant or Placebo Nasal Spray Plus a New Standard-of-care Oral Antidepressant in Adult and Elderly Participants With Treatment-resistant Depression

Depressive Disorder, Treatment-Resistant
Peking University

Not yet recruiting

Esketamine Adjuvant Therapy for Patients With Chronic Visceral Pain Comorbid Major Depressive Disorder

Major Depressive Disorder | Chronic Visceral Pain
The University of Texas Health Science Center,...

Terminated

Efficacy And Tolerability Of Sub-Anesthetic Ketamine In Postpartum Depression

Post Partum Depression

United States
Rhode Island Hospital

Completed

Intranasal Ketamine for Procedural Sedation in Pediatric Laceration Repair

Laceration

United States
Hospices Civils de Lyon

Completed

Effectiveness of Ketamine Administered by Mesotherapy in Complex Regional Pain Syndrome Type 1 (CRPS1) (MESO-SDRC)

Neuropathic Pain | Complex Regional Pain Syndrome Type 1

France
Lawson Health Research Institute

Withdrawn

INK Feasibility Study

Procedural Sedation
Javelin Pharmaceuticals

Completed

Absolute Bioavailability and Nasopharyngeal Absorption of Intranasal Ketamine

Healthy

United States
Universidade Federal de Goias
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Completed

Midazolam and Ketamine Effect Administered Through the Nose for Sedation of Children for Dental Treatment (NASO)

Dental Caries | Child Behavior

Brazil
Kowa Research Institute, Inc.

Completed

A Comparison Study to Evaluate the Pharmacokinetics and Safety of NK-104-CR in Healthy Adult Volunteers

Hyperlipidemia

United States

3

Subscribe