Search clinical trials for: Investigational drug

Total 256757 results

Novartis

Completed

Safety and Efficacy of ACZ885 in Adult Patients With Established Rheumatoid Arthritis

Rheumatoid Arthritis

Russian Federation, Spain, Turkey, Switzerland
Abion Inc

Completed

To Evaluate the Safety, Pharmacokinetic and the Effect of Food After Administration of ABN401 in Healthy Adult Volunteers

Solid Tumor

Korea, Republic of
Mayo Clinic
Elira Therapeutics, Inc.

Terminated

Effect of T6 Dermatome Electrical Stimulation on Gastroduodenal Motility in Healthy Volunteers

Weight Loss

United States
Hologic, Inc.

Completed

A Pilot Study - Comparison of Two Hologic 3D Mammography Systems

Breast Cancer
Francisco Baldaque-Silva

Recruiting

Role of Doppler Endoscopic Probe in the Diagnosis of Subepithelial Gastrointestinal Lesions. (DopplerSEL)

Subepithelial Tumors of the Upper Gastrointestinal Tract

Sweden
Centre Hospitalier Universitaire de Besancon

Unknown

Access to Maternity and Risk Factors in a Non-consultant Population (PROXIMA)

Post Partum Depression

France
Philips Clinical & Medical Affairs Global

Completed

Pediatric Liver Fat Quantification (LFQ) Phase 2 Pilot Study

Non-Alcoholic Fatty Liver Disease | Non-Alcoholic Steatohepatitis

United States
GlaxoSmithKline

Completed

A Study to Test if a Third Dose of the Vaccine is Safe in Current and Former Smokers Aged 40 to 80 Years Old and to Gather Information on the Immune Response Following the Third Dose of the Vaccine

Respiratory Disorders

Germany, Canada, United Kingdom
GlaxoSmithKline

Completed

A Study to Test if the Vaccine is Working Well in Chronic Obstructive Pulmonary Disease (COPD) Patients Aged 40 to 80 Years Old to Reduce Episodes of Worsening Symptoms and to Gather Further Information on Safety and Immune Response.

Respiratory Disorders

France, Germany, Spain, United States, Belgium, Italy, Canada, United Kingdom
International Partnership for Microbicides, Inc.

Completed

Observational Study of HIV Infection in Participants of Seroconvert During Dapivirine Vaginal Ring Trials

HIV Infections

South Africa, Rwanda
Danderyd Hospital
Karolinska University Hospital; Karolinska Institutet; Uppsala University Hospital

Recruiting

Cognitive Impairment and Fatigue After Mild to Moderate COVID-19

Cognitive Impairment | Post COVID-19 Condition | Fatigue, Mental

Sweden
Ain Shams University

Recruiting

Correlation Between Cardiac Markers and Severity of COVID-19

Cardiac Event

Egypt
Vanderbilt University Medical Center

Active, not recruiting

A Pharmacist-Led Intervention to Increase Inhaler Access and Reduce Hospital Readmissions (PILLAR) (PILLAR)

Asthma | COPD

United States
University of Zurich

Completed

Urodynamic Assessment of the Lower Urinary Tract: Water vs. Air - Synchrony

Lower Urinary Tract Dysfunction

Switzerland
University of Zurich

Completed

Urodynamic Assessment of the Lower Urinary Tract: Water vs. Air

Lower Urinary Tract Dysfunction

Switzerland
Sahar Ahmed Abdalbary

Completed

Myth of Double Crush Syndrome in Median Nerve (cadaveric)

Cervical Radiculopathy | Median Nerve Disease

Egypt
Assistance Publique Hopitaux De Marseille

Unknown

Assessing the Quality of Life of Caregivers and Before and After the Position of Gastronomy

Gastrostomy

France
Aalto University
Helsinki University Central Hospital; Business Finland

Recruiting

Early Identification of Age-related Hearing Impairment

Hearing Loss, Age-Related

Finland
Yonsei University

Unknown

A Clinical Trial of Silk Peptide for the Evaluation of Efficacy on Immune Function

Normal Healthy Subjects

Korea, Republic of
Yonsei University

Completed

A Clinical Trial of Bio-Germanium for the Evaluation of Efficacy on Immune Function (NYG)

Normal Healthy Subjects

Korea, Republic of
Johnson & Johnson Vision Care, Inc.
Ohio State University

Completed

Assessment of Daily Disposable Silicone Hydrogel Lens Wear

Myopia

United States
GlaxoSmithKline

Completed

Safety and Efficacy of H1N1 Vaccines in Children Aged 6 Months to Less Than 10 Years of Age

Influenza

Thailand, Australia, Mexico, Costa Rica, Philippines, Colombia, Singapore, Brazil
Sinovac Biotech Co., Ltd

Completed

Safety and Immunogenicity Study of 23-valent Pneumococcal Polysaccharide Vaccine in Healthy Children, Adults and Elderly

Pneumococcal Infections

China
University Hospital, Montpellier
Aix Marseille Université; LBM- Nanosecurity platform - CEA Grenoble; LR2N - Nanosecurity...

Terminated

Nanoparticles Emitted by Aircraft Engines, Impact on the Respiratory Function: (NANOAF2)

Air France Company's Employees Working in the Marseilles and Paris Airports (Flightline and Administrative Employees)

France
Royal Marsden NHS Foundation Trust

Completed

SuPr Study (Supine Versus Prone Treatment Position in Breast Radiotherapy) (SuPr)

Breast Cancer

United Kingdom
University of California, San Francisco
Jazz Pharmaceuticals

Not yet recruiting

Neoadjuvant Lurbinectedin and Preoperative Radiation for Treating Soft Tissue Sarcomas

Locally Advanced Soft Tissue Sarcoma

United States
RWTH Aachen University

Unknown

Video Assisted Pericardioscopic Surgery: Minimal-invasive Implantation of Epimyocardial Pacemaker Leads in Humans (VAPS)

Heart Failure | Bradycardia | Hemodialysis-Induced Symptom | Pacemaker Electrode Infection | Dysrhythmia, Cardiac

Germany
Sohag University

Active, not recruiting

Novel Classification of Adult-onset Diabetes and Its Association With Common Microvascular Complications in Upper Egypt

Diabetes Mellitus, Type 2

Egypt
Lupin Ltd.

Completed

Immunogenicity Assessment of Peg-filgrastim vs. Neulasta® as Adjunct to Chemotherapy in Patients With Breast Cancer

Breast Cancer

India
Johns Hopkins University
Boston Medical Center

Completed

Feasibility and Accuracy of a Novel Xpert Cartridge ((XpertDST))

Tuberculosis
Nantes University Hospital

Completed

Characterization of the Digestive Functions and the Enteric Nervous System in Obesity. Investigations of Relationships With Metabolism Disorders (EnteroNeurObesity)

Obesity

France
Johnson & Johnson Vision Care, Inc.

Completed

Evaluation of a Daily Disposable Silicone Hydrogel Multifocal Contact Lens in Myopes and Hyperopes

Visual Acuity

United States
AnHeart Therapeutics Inc.

Completed

A First-in-human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of DS-6051b

Solid Tumors

United States
Assiut University

Not yet recruiting

Risk Factors and Prognostic Parameters of Interstitial Lung Disease in Children

Interstitial Lung Disease
Fisher and Paykel Healthcare

Completed

Efficacy of NIV Masks in COPD

COPD

New Zealand
Maastricht University Medical Center

Unknown

Brain Areas Involved in Bladder Filling and Contraction

Urinary Bladder, Overactive

Netherlands
PolyMedix, Inc.

Completed

Initial Treatment for Acute Bacterial Skin Infections (ABSSSI) Caused by Staphylococcus Aureus

Acute Bacterial Skin and Skin-structure Infection(ABSSSI) Due to Staphylococcus Aureus (MSSA) | (Susceptible or Methicillin Resistant)

Canada, Russian Federation, Ukraine
Sangamo Therapeutics
Sanofi

Completed

A Study to Assess the Safety, Tolerability, and Efficacy of ST-400 for Treatment of Transfusion-Dependent Beta-thalassemia (TDT)

Transfusion Dependent Beta-thalassemia

United States
Sinovac (Dalian) Vaccine Technology Co., Ltd.

Completed

An Open-labelled Clinical Trial of Live Attenuated Varicella Vaccines to Evaluate the Immunity Persistence After Primary Immunization and Safety and Immunogenicity After the Booster Immunization

Varicella

China
GlaxoSmithKline
Aeras

Completed

Study in Healthy Adults to Evaluate Gene Activation After Vaccination With GlaxoSmithKline (GSK) Biologicals' Candidate Tuberculosis (TB) Vaccine GSK 692342

Tuberculosis

Belgium
Abbott Medical Optics

Completed

Clinical Investigation of the Next-Generation Intraocular Lens

Cataract

United States
Karolinska Institutet
Lund University; Uppsala University; The Swedish Research Council; Umeå University and other collaborators

Recruiting

Atrial Fibrillation Screening Post Ischemic Cerebrovascular Events (AF-SPICE)

Ischemic Stroke | TIA

Sweden
Umeå University

Completed

Reference Values of Cerebrospinal Fluid Outflow Resistance and Intracranial Pressure in Healthy Elderly

Healthy Elderly

Sweden
Johnson & Johnson Surgical Vision, Inc.

Active, not recruiting

Clinical Investigation of the TECNIS® Next-Generation Intraocular Lens, Model DEN00V

Cataracts

United States
Enterin Inc.

Completed

Orally Administered ENT-01 for Parkinson's Disease-Related Constipation (KARMET) (KARMET)

Parkinson Disease | Constipation

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Terminated

Precision Medicine for Patients With Identified Actionable Mutations

Lymphoma | Multiple Myeloma | Solid Tumor | Malignant Neoplasm | Mutation Abnormality

United States
KBio Inc
Boston University; National Institute of Allergy and Infectious Diseases (NIAID) and other collaborators

Completed

Safety Study of Monoclonal Antibodies to Reduce the Vaginal Transmission of HSV and HIV (VAST)

HIV | Herpes Simplex Infections

United States
Cytori Therapeutics

Withdrawn

Safety and Feasibility of ADRCs (Adipose Derived Regenerative Cells) in Patients With Grade II Hamstring Tears (RECOVER)

Muscle Tear

United States
University of Zurich

Recruiting

Longitudinal Investigation of Brain Blood Flow Changes in Neurosurgical Patients

Brain Blood Flow Impairment

Switzerland
Brigham and Women's Hospital
Boston Medical Center

Recruiting

NAD Augmentation in Diabetes Kidney Disease (DKD)

Diabetic Kidney Disease | Type2diabetes

United States

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