Search clinical trials for: Isotonic saline 0.9%

Total 15087 results

Xijing Hospital

Recruiting

LAAO Versus NOAC in Patients With AF and PCI

Atrial Fibrillation | Percutaneous Coronary Intervention

China
Rong Zhang
National Institute on Aging (NIA); Michigan State University; Texas Health Resources

Recruiting

Impact of Intensive Treatment of SBP on Brain Perfusion, Amyloid, and Tau (IPAT Study) (IPAT)

Hypertension | Subjective Cognitive Decline | Cognitively Normal Older Adults | Family History of Dementia

United States
Medical University of Gdansk
Institute of Cardiology, Warsaw, Poland; Medical University of Silesia; Pomeranian... and other collaborators

Recruiting

Dual Antithrombotic Therapy With Dabigatran and Ticagrelor in Patients With ACS and Non-valvular AF Undergoing PCI (ADONIS-PCI)

Atrial Fibrillation | Acute Coronary Syndrome | Antithrombotic Therapy | Percutaneous Coronary Interventions

Poland
University of Washington
Merck Sharp & Dohme LLC; Prometheus Laboratories

Terminated

Aldesleukin and Pembrolizumab in Treating Patients With Advanced or Metastatic Kidney Cancer

Metastatic Clear Cell Renal Cell Carcinoma | Stage III Renal Cell Cancer | Advanced Clear Cell Renal Cell Carcinoma | Stage IV Renal Cell Cancer

United States
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Completed

Edoxaban Treatment Versus Vitamin K Antagonist in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention (ENTRUST-AF-PCI)

Atrial Fibrillation

Italy, Netherlands, Spain, Korea, Republic of, Portugal, Hungary, Serbia, United Kingdom, Germany, Belgium, Taiwan, Austria, Switzerland, France, Ukraine, Lithuania, Poland, Romania
Janssen Research & Development, LLC
Harvard Medical School (HMS and HSDM); Bayer; Duke Clinical Research Institute

Completed

A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome (GEMINI ACS 1)

Acute Coronary Syndrome

United States, France, Poland, Ukraine, Belgium, Spain, Argentina, Bulgaria, Russian Federation, Turkey, Japan, Canada, Netherlands, Korea, Republic of, Brazil, Australia, Hungary, Sweden, Czechia, Denmark
Odessa Heart Institute

Completed

Simplified Anti-Thrombotic Therapy for FFR (SMART-FFR)

Coronary Artery Disease
Italian Society of Invasive Cardiology
Eustrategy

Unknown

Minimizing Adverse Haemorrhagic Events by TRansradial Access Site and Systemic Implementation of angioX (MATRIX)

STEMI | Acute Coronary Syndromes | NSTEMI

Italy
Maher elesawi kamel elesawi

Unknown

Surgery Plus Single Agent Chemotherapy Versus Primary Chemotherapy for Gestational Trophoblastic Neoplasms (SVCGTN)

Gestational Trophoblastic Neoplasms

Egypt
Sun Yat-sen University

Unknown

A Pilot Study of Genomic Sequencing Guided Individualized Therapy in Gastrointestinal Cancers, GITIC Study (GITIC)

Gastrointestinal Cancers

China
Juan A. Arnaiz

Completed

Intermittent ART in Primary HIV Infection (PHI-IL2)

HIV

Spain
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Comparing Enbrel (Etanercept) Plus Methotrexate Versus Enbrel Alone in Active Rheumatoid Arthritis Despite Current Methotrexate Therapy

Rheumatoid Arthritis
Rigshospitalet, Denmark
Aarhus University Hospital Skejby

Recruiting

The Nordic Aortic Valve Intervention Trial 4 (NOTION-4) (NOTION-4)

Heart Diseases | Cardiovascular Diseases | Aortic Valve Stenosis | Heart Valve Diseases | Valve Disease, Aortic

Denmark
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Adaptive Platform Trial for Personnalisation of Sepsis Treatment in Children and Adults: a Multi-national, Treatable Traits-guided, Adaptive, Bayesian Basket Trial (PALETTE)

Sepsis
Xijing Hospital

Recruiting

Low-dose NOAC Versus GDMT After LAAO (RECORD-III)

Atrial Fibrillation

China
University of Zurich
Swiss National Science Foundation

Recruiting

MidregiOnal Proatrial Natriuretic Peptide to Guide SEcondary Stroke Prevention (MOSES)

Stroke, Ischemic

Spain, United Kingdom, Switzerland, Greece, Norway
Population Health Research Institute
Bayer

Completed

Anti-Coronavirus Therapies to Prevent Progression of Coronavirus Disease 2019 (COVID-19) Trial (ACTCOVID19)

Severe Acute Respiratory Syndrome | Coronavirus

Egypt, Canada, Brazil, Colombia, Ecuador, India, Nepal, Pakistan, Philippines, Russian Federation, South Africa, United Arab Emirates
University of Washington
National Institute of General Medical Sciences (NIGMS)

Completed

CYP3A4 Activity and Mineral Homeostasis

Vitamin D and Calcium Homeostasis

United States
Ottawa Hospital Research Institute
The Ottawa Hospital

Completed

Pilot Study to Examine the Use of Rivaroxaban After Angioplasty for Critical Limb Ischemia (RIVAL-PAD)

Critical Limb Ischemia

Canada
National Cancer Institute (NCI)

Completed

Aldesleukin With or Without Ziv-Aflibercept in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery

Metastatic Melanoma | Stage III Cutaneous Melanoma AJCC v7 | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Recurrent Melanoma | Stage IIIC Cutaneous Melanoma AJCC v7 | Stage IIIA Cutaneous Melanoma AJCC v7 | Stage IIIB Cutaneous Melanoma AJCC v7

United States
Daiichi Sankyo, Inc.
UMC Utrecht

Completed

Edoxaban in Peripheral Arterial Disease (ePAD)

Peripheral Arterial Disease

United States, Germany, Switzerland, Israel, Netherlands, Austria, Belgium
Scripps Health
Daiichi Sankyo, Inc.

Unknown

A Pilot Study of Edoxaban in Patients With Non-Valvular Atrial Fibrillation and Left Atrial Appendage Closure

Non-Valvular Atrial Fibrillation | Left Atrial Appendage Closure

United States
Sally Arai

Completed

Post-transplant Autologous Cytokine-induced Killer (CIK) Cells for Treatment of High Risk Hematologic Malignancies

Leukemia | Multiple Myeloma

United States
National Cancer Institute (NCI)

Terminated

Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane Hydrochloride in Treating Young Patients With Relapsed or Refractory Solid Tumors, Lymphoma, or Leukemia

Unspecified Childhood Solid Tumor, Protocol Specific | Peripheral T-cell Lymphoma | Angioimmunoblastic T-cell Lymphoma | Childhood Chronic Myelogenous Leukemia | Cutaneous B-cell Non-Hodgkin Lymphoma | Hepatosplenic T-cell Lymphoma | Intraocular Lymphoma | Recurrent Childhood Acute Lymphoblastic... and other conditions

United States, Canada
National Cancer Institute (NCI)
NRG Oncology

Completed

Capecitabine, Bevacizumab, and Radiation Therapy Followed By Gemcitabine and Bevacizumab in Treating Patients With Locally Advanced Pancreatic Cancer That Cannot Be Removed By Surgery

Adenocarcinoma of the Pancreas | Stage III Pancreatic Cancer | Stage II Pancreatic Cancer

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating Strategies to Reduce Mother-to-Child Transmission of HIV Infection in Resource-Limited Countries (PROMISE)

HIV Infections

Malawi, South Africa, Tanzania, Zimbabwe, India, Uganda, Zambia
Roswell Park Cancer Institute

Recruiting

Genetically Engineered Cells (EGFRt/19-28z/IL-12 CAR T Cells) for the Treatment of Relapsed or Refractory CD19+ Hematologic Malignancies

Recurrent Mantle Cell Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Chronic Lymphocytic Leukemia | Refractory Mantle Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma | Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell... and other conditions

United States
Karolinska Institutet

Terminated

Goal Directed Haemodynamic Treatment for Patients With Proximal Femoral Fracture (GDHT)

Femoral Fracture

Sweden
Japan Adult Leukemia Study Group

Completed

Study of Imatinib-Combined Chemotherapy for BCR-ABL-Positive Acute Lymphoblastic Leukemia (ALL)

Acute Lymphoblastic Leukemia

Japan
Inonu University

Not yet recruiting

Dose Low Dose Ketamine in Casesarian

Postoperative Pain | Postpartum Depression

Turkey
Kansas City Heart Rhythm Research Foundation
Cardiac Arrhythmia Service, Loma Linda University Health, Loma Linda, CA

Not yet recruiting

Effectiveness of Bupivacaine, Ketorolac, Ketamine, vs Bupivacaine Alone in Reducing Postoperative Pocket Pain

Pain Management

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors

Prognostic Stage IIIC Breast Cancer AJCC v8 | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Melanoma | Stage IV Lung Cancer AJCC v8 | Locally Advanced Malignant Solid Neoplasm | Locally... and other conditions

United States
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

Oral Cavity Squamous Cell Carcinoma | Stage I Lip and Oral Cavity Cancer AJCC v8 | Stage II Lip and Oral Cavity Cancer AJCC v8 | Buccal Mucosa Squamous Cell Carcinoma | Floor of Mouth Squamous Cell Carcinoma | Gingival Squamous Cell Carcinoma | Hard Palate Squamous Cell Carcinoma | Lip Squamous Cell... and other conditions

United States, Canada
Central European Society for Anticancer Drug Research

Completed

Sequential Therapy in Metastatic Renal Cell Carinoma (BERAT)

Metastatic Renal Cell Carcinoma

Germany
Unita Complessa di Ostetricia e Ginecologia
Schering-Plough

Completed

Testosterone and Its Metabolites in GID

Transsexualism

Italy
Assistance Publique - Hôpitaux de Paris

Unknown

Efficacy and Safety of DAPSone as a Second-line Option in Adult Immune Thrombocytopenia (DAPS-ITP)

Adult Immune Thrombocytopenia (ITP) | Dapsone

France
University of Sao Paulo
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Completed

Effect of Intracervical on the Pain Associated With the Insertion of the LNG-IUS

Pain

Brazil
Prescient Therapeutics, Ltd.
National Cancer Institute (NCI)

Terminated

PTX-200, Paclitaxel, Doxorubicin Hydrochloride, and Cyclophosphamide in Treating Patients With Stage IIB-IV Breast Cancer

Stage IV Breast Cancer | Recurrent Breast Carcinoma | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IIB Breast Cancer | Stage IIIC Breast Cancer | Estrogen Receptor Positive | HER2/Neu Negative | Breast Adenocarcinoma

United States
Peking University Third Hospital

Recruiting

A Clinical Study to Evaluate the Pharmacokinetics of Microdose Midazolam, Dabigatran, Pitavastatin, Atorvastatin and Rosuvastatin in Healthy Volunteers and Renal Impairment Patients

Chronic Kidney Disease

China
Sarmad Zahoor
Mayo Hospital Lahore; University of Managemant and Technology, Pakistan

Not yet recruiting

To Assess the Efficacy and Safety of Dual Anticoagulants i.e. Rivaroxaban Plus Aspirin and Clopidogrel Plus Aspirin in Patients Suffering From an Acute Coronary Syndrome (ACCP)

Acute Coronary Syndrome
Clinical Hospital Centre Zagreb
Croatian Science Foundation; University of Zagreb School of Medicine

Recruiting

Pharmacogenomics in Prediction of Cardiovascular Drugs Adverse Reaction

Drug-Related Side Effects and Adverse Reactions | Pharmacogenetics | Cardiovascular Drugs

Croatia
Mercy Health Ohio

Recruiting

A Comparison of Ultrasound-guided Steroid Injection With Wrist Splint in Carpal Tunnel Syndrome

Carpal Tunnel Syndrome

United States
National Institute of Allergy and Infectious Diseases...

Completed

Using Biomarkers to Predict TB Treatment Duration

Pulmonary Tuberculosis

South Africa
Enanta Pharmaceuticals, Inc
Pharmaceutical Research Associates

Completed

Drug-Drug Interaction Study Between EDP-938, Tacrolimus, Dabigatran, Rosuvastatin and Midazolam in Healthy Subjects

RSV Infection

United States
Universidade do Vale do Sapucai
Pfizer; Apsen Farmaceutica S.A.; Biofarma; Dermadia; Methodos Laboratory

Completed

Prevention of Complications (SARS-CoV-2): Clinical Study

Complication

Brazil
Baxalta now part of Shire
Kamada, Ltd.

Terminated

A Phase 2/3 Study of GLASSIA for the Treatment of Acute GvHD

Graft Versus Host Disease

United States
Bristol-Myers Squibb
Pfizer; Duke Clinical Research Institute

Completed

A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart

Acute Coronary Syndromes

Australia, Germany, Poland, United States, Spain, Brazil, France, Netherlands, Argentina, Mexico, Russian Federation, Colombia, Austria, Belgium, Czechia, Hungary, Israel, Peru, Switzerland, Korea, Republic of, Canada, Romania, Sweden, Ukrai... and more
Stanford University

Completed

High-Dose Sequential Therapy and Single Autologous Transplantation for Multiple Myeloma

Multiple Myeloma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Donor Natural Killer Cells and Donor Stem Cell Transplant in Treating Patients With High Risk Myeloid Malignancies

Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Acute Erythroid Leukemia | Acute Megakaryoblastic Leukemia | Myelodysplastic Syndrome | High Risk Myelodysplastic Syndrome | Blast Phase Chronic Myelogenous Leukemia,... and other conditions

United States
University Hospital, Basel, Switzerland

Completed

Pharmacokinetic Study to Characterize Phenotyping Metrics of the "Basel" Cocktail After CYP Induction or Inhibition

Metabolic Detoxication, Phase I

Switzerland

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