Search clinical trials for: JAK Inhibitor

Total 64704 results

Takeda
Takeda Development Center Americas, Inc.

Completed

A Study to Determine the Safety, Tolerability, and Pharmacokinetics of Lanadelumab Administered Intravenously in Healthy Adult Volunteer Participants

Healthy Volunteers

United States
Takeda

Completed

A Study to Evaluate the Effect of High-Fat Meal on TAK-788 Pharmacokinetics (PK) in Healthy Adult Participants

Healthy Volunteers

United States
Millennium Pharmaceuticals, Inc.

Completed

Study of TAK-935 as an Adjunctive Therapy in Adult Participants With Complex Regional Pain Syndrome (CRPS)

Complex Regional Pain Syndrome

United Kingdom
Millennium Pharmaceuticals, Inc.

Withdrawn

Study of TAK-733 in Combination With Alisertib in Adult Patients With Advanced Nonhematologic Malignancies

Advanced Nonhematologic Malignancies

United States
Akros Pharma Inc.

Terminated

Two Week Study Evaluating Safety, Tolerability and Pharmacokinetics of Multiple Doses of JTK-853 in Healthy Subjects

Healthy

United States
H Scott Boswell
Takeda

Terminated

Study Augmenting TAK-659 Action in Relapsed/Refractory AML by Addition Ofthe Proteasome Inhibitor Ixazomib

AML | AML, Adult

United States
Takeda

Terminated

Comparison of Fasiglifam (TAK-875) With Sitagliptin When Used in Combination With Metformin in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, Ukraine, Poland, Malaysia, Canada, Peru, Philippines, Hungary, Russian Federation, South Africa, Argentina, Croatia, Thailand
Kaiser Permanente
AbbVie

Completed

Real World Study: Genotype 1 Chronic Hepatitis C Virus Treatment and Evaluation of Real World SVR and PRO

Hepatitis C, Chronic

United States
National Cancer Institute (NCI)

Recruiting

Testing of the Anti Cancer Drugs CB-839 HCl (Telaglenastat) and MLN0128 (Sapanisertib) in Advanced Stage Non-small Cell Lung Cancer

Metastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Brain | Leptomeningeal Neoplasm | Recurrent Lung Non-Small Cell Carcinoma

United States
Ethicon Endo-Surgery

Completed

A Prospective, Single-Arm Multi-Center Study of the ENSEAL X1 Curved Jaw Tissue Sealer in Select Procedures

Upper GI; Lower GI; Gynecological

United Kingdom, United States, Italy
Takeda

Active, not recruiting

A Study of TAK-625 for the Treatment of Progressive Familial Intrahepatic Cholestasis (PFIC)

Progressive Familial Intrahepatic Cholestasis (PFIC)

Japan
Millennium Pharmaceuticals, Inc.

Completed

A Study to Evaluate Pharmacokinetics (PK) and Safety of Oral Mobocertinib in Participants With Moderate or Severe Hepatic Impairment (HI) and Normal Hepatic Function

Healthy Volunteers | Hepatic Impairment

United States
Takeda

Completed

A Study of Danavorexton (TAK-925) in Adults With Obstructive Sleep Apnea

Sleep Apnea

Australia
Millennium Pharmaceuticals, Inc.

Completed

Dose Escalation Study of MLN0128 in Participants With Advanced Malignancies

Advanced Solid Malignancies

United States, Spain
Millennium Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability of TAK-788 Followed by Evaluation of the Effects of a Low-Fat Meal on TAK-788 PK and Evaluation of Relative Bioavailability of TAK-788 Capsules in Healthy Participants

Healthy Volunteers

United States
United States Naval Medical Center, San Diego

Completed

Jaw Elevation Device in Deep Sedation Study

Airway Obstruction

United States
Takeda

Terminated

Efficacy and Safety of Resatorvid in Patients With Sepsis-induced Cardiovascular and Respiratory Failure

Sepsis

Japan
Takeda

Completed

Efficacy of Ramelteon in Subjects With Chronic Insomnia

Sleep Initiation and Maintenance Disorders

United States
Akros Pharma Inc.

Completed

Safety, Tolerability and Pharmacokinetics Study Assessing Ascending Single Oral JTK-853 Doses in Healthy Subjects

Healthy

United States
Joyce O'Shaughnessy
Takeda

Completed

TAK-228 and TAK-117 Followed by Cisplatin and Nab Paclitaxel for Metastatic Triple Negative Breast Cancer

Triple Negative Breast Cancer

United States
Millennium Pharmaceuticals, Inc.

Completed

A Study of Mobocertinib Capsules in People With Severe Kidney Problems and People With Healthy Kidneys

Renal Impairment | Healthy Volunteers

United States
Karen D. Wright, MD
National Cancer Institute (NCI); Pacific Pediatric Neuro-Oncology Consortium; Day One Biopharmaceuticals, Inc... and other collaborators

Active, not recruiting

DAY101 In Gliomas and Other Tumors

Low-grade Glioma

United States
AstraZeneca
Takeda; Covance; Catalent; MMS Holdings, Inc

Completed

Single Ascending Dose Study of MEDI1341 in Healthy Volunteers

Parkinson's Disease

United States
AstraZeneca
Takeda

Completed

Multiple Ascending Dose Study of MEDI1341 in Patients With Parkinson's Disease

Parkinson's Disease

United States
Istanbul Physical Medicine Rehabilitation Training...

Completed

the Relationship Between Parafunctional Habits, Pain and Functional Limitation of the Jaw

Temporomandibular Disorder | Pain, Joint

Turkey
Neurocrine Biosciences
Takeda

Completed

Study to Determine D-amino Acid Oxidase Brain Enzyme Occupancy of TAK-831 After Single-dose Oral Administration

Healthy

United Kingdom
Takeda
COUR Pharmaceutical Development Company, Inc.

Completed

Study of the Safety, Tolerability and Pharmacokinetics of TIMP-GLIA in Subjects With Celiac Disease

Celiac Disease

United States
Takeda

Completed

The Exploratory Study to Investigate the Effect of Ramelteon for Insomnia Patients With Major Depressive Disorder by Using Actigraphy

Insomnia | Major Depressive Disorder

Japan
Queen's University, Belfast
Glasgow Caledonian University; University of Glasgow

Completed

The If I Were Jack Feasibility Trial

Healthy Cohort

United Kingdom
Takeda

Completed

Pharmacokinetic and Safety of Ramelteon Between Adolescents With Insomnia and Healthy Adults

Insomnia

United States
Takeda

Completed

Efficacy & Safety of Resatorvid in Adults With Severe Sepsis

Sepsis

United States, United Kingdom, Belgium, Germany, Spain, Israel, Japan, Australia, Canada, Finland, Netherlands, New Zealand, Czech Republic, Puerto Rico, Austria, Sweden, Italy
Millennium Pharmaceuticals, Inc.

Terminated

MLN1117 in Combination With Docetaxel, Paclitaxel, and Other Investigational Anticancer Agents to Treat Participants With Gastric and Gastroesophageal Adenocarcinoma

Advanced and Metastatic Gastric or Gastroesophageal Adenocarcinoma

United States, Spain
M.D. Anderson Cancer Center

Completed

Osimertinib in Combination With Alisertib or Sapanisertib for the Treatment of Osimertinib-Resistant EGFR Mutant Stage IIIB or IV Non-Small Cell Lung Cancer

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Recurrent Lung Non-Small Cell Carcinoma

United States
Takeda

Recruiting

A Survey of Lanadelumab in Participants With Hereditary Angioedema

Hereditary Angioedema (HAE)

Japan
Neurocrine Biosciences

Completed

Study to Assess the Efficacy and Safety of NBI-1065845 in Adults With Major Depressive Disorder (MDD) (SAVITRI)

Major Depressive Disorder

United States, Czechia, Bulgaria, Poland, Slovakia, Sweden
Takeda

Available

Expanded Access Program of TAK-755 for Congenital Thrombotic Thrombocytopenic Purpura (cTTP)

Thrombotic Thrombocytopenic Purpura (TTP)
University of Minnesota
National Institute of Dental and Craniofacial Research (NIDCR); HealthPartners...

Completed

Assessing a New Jaw Support Device During Third Molar Extractions

Temporomandibular Disorder | Impacted Third Molar Tooth

United States
MarsiBionics

Completed

Evaluation of the Safety and Usability of the MAK Exoskeleton in Patients With Stroke

Stroke | Gait, Hemiplegic

Spain
Takeda

Completed

Drug Use Surveillance of Vonoprazan for "Gastric Ulcer, Duodenal Ulcer, and Reflux Esophagitis"

Gastric Ulcer, Duodenal Ulcer, and Reflux Esophagitis

Japan
Keimyung University Dongsan Medical Center

Unknown

Jaw-thrust on Postoperative Sore Throat

General Anesthesia

Korea, Republic of
Takeda

Completed

Efficacy and Safety of Ramelteon in Subjects With Mild to Moderate Alzheimer's Disease

Chronic Insomnia

United States
Takeda

Terminated

Efficacy of Lapaquistat Acetate on Blood Cholesterol Levels in Treating Subjects With Hypercholesterolemia

Hypercholesterolemia

Ukraine, Spain, Israel, Netherlands, Estonia, Russian Federation, Hungary, Norway, United Kingdom, Slovakia, Latvia
Takeda

Completed

A Unblinded Study of TAK-438 (20 mg) for Prevention of Recurrence of Gastric or Duodenal Ulcer During Long-Term Low-Dose Aspirin Therapy

Gastric Ulcer | Duodenal Ulcer

Japan
Millennium Pharmaceuticals, Inc.

Completed

MLN0128 and MLN0128 + MLN1117 Compared With Everolimus in the Treatment of Adults With Advanced or Metastatic Clear-Cell Renal Cell Carcinoma

Clear-cell Metastatic Renal Cell Carcinoma

Spain, Czechia, United States, Canada, Italy, United Kingdom, France, Poland
Takeda

Withdrawn

Phase 1 Dexlansoprazole Delayed-Release Capsules for Acid-Related Disorders in Infants Aged 1 to 11 Months

Pediatric Gastroesophageal Reflux Disease

United States, Italy, Israel, Mexico, Poland
Badr University

Not yet recruiting

Post Extraction Wound Healing Evaluation of Immediate Complete Denture Using IPR Scale

Complete Edentulism Due to Periodontal Disease (Disorder)
Alcon Research

Completed

Clinical Comparison of 27+® and 23-gauge ULTRAVIT® 7500 Cpm Vitrectomy Outcomes

Vitreoretinal Disease

United States
University of Reading

Recruiting

Impact of Consumption of Cowpea Leaves on Blood Glucose

Blood Glucose

United Kingdom
Takeda

Recruiting

An Absorption, Distribution, Metabolism, Excretion (ADME) Study of [14C]Subasumstat in Adults With Advanced or Metastatic Solid Tumors

Solid Tumors

Hungary
Takeda
Nimbus Lakshmi, Inc.

Completed

A Study to Evaluate the Efficacy, Safety, and Tolerability of NDI-034858 in Participants With Active Psoriatic Arthritis

Psoriatic Arthritis

United States, Czechia, Germany, Poland

Search clinical trials for: JAK Inhibitor

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in France

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations