Search clinical trials for: LINZESS®

Total 13824 results

Donald Trump, MD

Terminated

Oral Calcitriol With Ketoconazole in CRPC

Castration-resistant Prostate Cancer

United States
Celgene

Completed

Study of Dose-dense Adriamycin Plus Cytoxan (AC) Followed by Either ABI-007 (Abraxane) or Taxol With Bevacizumab as Adjuvant Therapy for Patients With Breast Cancer

Breast Cancer

United States
St. Jude Children's Research Hospital
Ohio State University; Arog Pharmaceuticals, Inc.

Completed

Crenolanib in Combination With Sorafenib in Patients With Refractory or Relapsed Hematologic Malignancies

Acute Myeloid Leukemia

United States
Par Pharmaceutical, Inc.
Novum Pharmaceutical Research Services

Terminated

Bioequivalence of Two Ciprofloxacin 0.3%/Dexamethasone 0.1% Sterile Otic Suspensions in Otitis Media in Children With Tympanostomy Tubes

Otitis Media in Patients With Tympanostomy Tubes

United States
Henan University of Traditional Chinese Medicine

Unknown

Effect of Traditional Chinese Medicine on Outcomes in Patients With Severe / Very Severe COPD

Pulmonary Disease, Chronic Obstructive
Dexa Medica Group

Completed

Bioequivalence Study of Two Formulations of Pregabalin Capsules 150 mg

Healthy

Indonesia
Alcon Research

Completed

Assessment of Alcon's Ocular Image Quantification System

Allergic Conjunctivitis

United States
PARZIBUT Gilles

Not yet recruiting

Non-inferiority Evaluation of Trimbow in Critically Ill Patients Admitted in ICU Compared to Standard of Care (TRIMICU)

COPD Exacerbation
Montefiore Medical Center

Recruiting

Pilocarpine Use After Kahook Goniotomy (PAACK)

Glaucoma

United States
Merck Sharp & Dohme LLC

Active, not recruiting

KEYMAKER-U01 Substudy 3: Efficacy and Safety Study of Pembrolizumab (MK-3475) When Used With Investigational Agents in Participants With Advanced Non-small Cell Lung Cancer (NSCLC), Previously Treated With Anti-programmed Cell Death Receptor Ligand 1 (PD-L1) Therapy (MK-3475-01C/KEYMAKER-U01C)

Carcinoma, Non-Small-Cell Lung

Poland, United States, Hungary, Israel, Italy, Korea, Republic of, Spain
Respirent Pharmaceuticals Co Ltd.
Becro Ltd.

Active, not recruiting

Bioequivalence Study for Fluticasone Propionate 250 mcg/Salmeterol Xinafoate 50 mcg Inhalation Powder in Healthy Volunteers

Bioequivalence

Greece
H. Lundbeck A/S
Takeda

Completed

Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Participants Aged 7 to 11 Years With Major Depressive Disorder (MDD)

Depressive Disorder, Major

Korea, Republic of, United States, Hungary, Poland, Spain, Serbia, Estonia, Bulgaria, Mexico, Russian Federation, Ukraine, Canada, Colombia, France, Germany, Israel, Italy, Latvia, South Africa
University of Alberta

Completed

Omental Islet Transplant

Type 1 Diabetes

Canada
El Shatby University Hospital for Obstetrics and...

Completed

Progestin Primed Double Stimulation Protocol Versus Flexible GnRH Antagonist Protocol in Poor Responders

Infertility, Female

Egypt
Danish Headache Center
Novartis Pharmaceuticals

Unknown

The Effect of Anti-calcitonin Gene-related Peptide (CGRP) Receptor Antibodies on the Headache Inducing Properties of CGRP and Cilostazol in Migraine Patients

Migraine | Migraine Without Aura | Migraine With Aura

Denmark
Nina Bhardwaj
Cancer Research Institute, New York City; Ludwig Institute for Cancer Research and other collaborators

Completed

Safety Study of Adjuvant Vaccine to Treat Melanoma Patients

Melanoma

United States
Avanir Pharmaceuticals

Terminated

Effectiveness, Safety, and Health-Related Outcomes of NUEDEXTA® in Nursing Home Patients With Pseudobulbar Affect (PBA)

Pseudobulbar Affect (Involuntary Laughing and/or Crying)

United States
Assistance Publique - Hôpitaux de Paris
Novartis

Completed

Evaluation of Low Dose Corticosteroids Efficiency, Associated With Myfortic ® in the Treatment of Nephrotic Syndrome (MSN)

Nephrotic Syndrome

France
AstraZeneca

Completed

Study to Assess the Bioavailability of Ticagrelor OD Tablet vs. IR Tablet

Healthy Subjects | Bioavailability

Germany
Yun-fei Xia

Unknown

Efficacy and Safety of FORRAD® for the Management of Radiation-induced Mucositis in Patients With Nasopharyngeal Carcinoma Receiving IMRT

Nasopharyngeal Neoplasms | Stomatitis

China
Boehringer Ingelheim

Completed

Efficacy of Buscopan® in Comparison With 654-II (Anisodamine) in Acute Gastric or Intestinal Pain

Intestinal Diseases

China
H. Lundbeck A/S

Completed

Randomised Placebo-controlled Duloxetine-referenced Efficacy and Safety Study of 2.5, 5 and 10 mg of Vortioxetine (Lu AA21004) in Acute Treatment of Major Depressive Disorder

Major Depressive Disorder
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Myelodysplastic/Myeloproliferative Diseases

United States
INSYS Therapeutics Inc

Completed

Pharmacokinetic Study of Fentanyl 400 µg Sublingual Spray, Actiq® 400 µg Transmucosally, and Fentanyl Citrate Injection 100 µg Intravenously (iv)

Pain

United States
M.D. Anderson Cancer Center
Allergan

Withdrawn

Topical Cyclosporine vs. Placebo for Epiphora Associated With Docetaxel

Epiphora
Baskent University

Completed

Intrathecal Levobupivacaine With Opioids for Caesarean Section

Elective Caesarean Section Surgeries

Turkey
European Organisation for Research and Treatment...
Novartis

Not yet recruiting

177Lu-DOTATATE for Recurrent Meningioma (LUMEN-1)

Recurrent Meningioma
Respirent Pharmaceuticals Co Ltd.
Becro Ltd.

Recruiting

Bioequivalence With Clinical Endpoint Study of Fluticasone Propionate 100 mcg and Salmeterol 50 mcg Inhalation Powder/Respirent Pharmaceuticals vs. ADVAIR DISKUS® 100/50 mcg Inhalation Powder/GSK in Patients With Asthma (AERO-PD)

Asthma

Greece
Fundació Institut de Recerca de l'Hospital de la...

Recruiting

Hemodynamic Optimization of Cerebral Perfusion After Endovascular Therapy in Patients With Acute Ischemic Stroke (HOPE)

Acute Ischemic Stroke

Spain
Genmab
AbbVie

Recruiting

Safety and Efficacy Study of Epcoritamab in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia and Richter's Syndrome (EPCORE™ CLL-1)

Small Lymphocytic Lymphoma | Richter's Syndrome | Relapsed/Refractory Chronic Lymphocytic Leukemia

United States, Belgium, Netherlands, Spain, Italy, Australia, Israel, France, Denmark, Czechia, Germany, United Kingdom
Astellas Pharma Global Development, Inc.

Active, not recruiting

A Study of ASP2215 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase (FLT3) Mutation

Leukemia, Acute Myeloid (AML)

Japan, United States, Belgium, Canada, France, Germany, Israel, Italy, Korea, Republic of, Poland, Spain, Taiwan, Turkey, United Kingdom
RAAS Nutritionals, LLC
Kayseri City Hospital

Completed

Effect of Kunamin in SARS-CoV-2 RT-PCR Positive Covid-19 Patients

COVID-19 Pneumonia | COVID-19 Respiratory Infection | Bacterial Pneumonia | FLU | Cold; Influenza

Turkey
Sanofi
Regeneron Pharmaceuticals

Completed

Effect of Sarilumab on Patient-reported Outcomes in Patients With Active Rheumatoid Arthritis (SariPRO)

Rheumatoid Arthritis

France
Respirent Pharmaceuticals Co Ltd.

Completed

A Clinical Trial for Examining the Therapeutic Equivalence Between Fluticasone Propionate 100 mcg and Salmeterol 50 mcg Inhalation Powder/Respirent Pharmaceuticals vs. ADVAIR DISKUS® 100/50 mcg Inhalation Powder/GSK in Patients With Asthma

Asthma

Greece
Chong Kun Dang Pharmaceutical

Completed

Impact of Lymphocyte Anti-metabolite Immunosuppressions on Donor-Specific Anti-HLA Antibody and Kidney Graft Outcome

Kidney Transplant

Korea, Republic of
Brown University
Lifespan; SouthCoast Medical Group; Memorial hospital

Completed

BrUOG 292: FOLFOX-A For Metastatic Pancreatic Cancer: A Phase II Brown University Oncology Research Group Trial

Metastatic Pancreatic Cancer

United States
Indivior Inc.

Completed

Buprenorphine-Fentanyl Interaction Study

Healthy | Opioid Use

Netherlands
Respirent Pharmaceuticals Co Ltd.
Becro Ltd.

Completed

A Bioequivalence Study Between Fluticasone Salmeterol Xinafoate vs. SERETIDE DISKUS® in Healthy Volunteers With Charcoal Blockade (BREATH-PK250-CC)

Bioequivalence

Greece
National Institute of Allergy and Infectious Diseases...
Immune Tolerance Network (ITN)

Completed

Combined Kidney and Bone Marrow Transplantation to Prevent Kidney Transplant Rejection

Kidney Failure, Chronic | Kidney Transplantation

United States
University of Utah

Completed

Hematopoietic Cell Transplantation for Pediatric Patients With Hematologic Malignancies

Lymphoma | Leukemia | Chronic Disease | Myelodysplasia | Acute Leukaemia

United States
Mylan Inc.
Mylan Bertek Pharmaceuticals

Terminated

Effects of Therapy With Sulfamylon® 5% Topical Solution Compared to a Historical Control Group

Burns

United States
Chiesi Farmaceutici S.p.A.

Completed

Efficacy of Fixed Combination of Beclometasone + Formoterol + Glycopyrrolate Versus Foster® in COPD

Chronic Obstructive Pulmonary Disease

Hungary
Merck Sharp & Dohme LLC

Completed

Study of MK-1029 in Participants With Persistent Asthma That Cannot Be Controlled With Montelukast (MK-1029-015)

Asthma
Boston Scientific Corporation

Completed

Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchronization Therapy Post Approval Registry (MADIT-CRT PAR)

Heart Failure

United States
Injury Care Medical Center
Nuvo Research Inc.

Unknown

Pain Patch Versus Injections in the Treatment of Pain Associated With Shoulder Impingement Syndrome

Shoulder Pain

United States
Amsterdam Molecular Therapeutics
The Clinical Trial Company

Completed

Efficacy and Safety of Human Lipoprotein Lipase (LPL)[S447X] Expressed by an Adeno-Associated Viral Vector in LPL-deficient Subjects

Familial Lipoprotein Lipase Deficiency

Canada
Merck Sharp & Dohme LLC
Pfizer

Completed

Ertugliflozin and Sitagliptin Co-administration Factorial Study (VERTIS FACTORAL, MK-8835-005)

Type 2 Diabetes Mellitus
National Institute of Allergy and Infectious Diseases...
Immune Tolerance Network (ITN)

Terminated

Belatacept to Prevent Organ Rejection in Kidney Transplant Patients (BESTT)

Renal Transplant

United States
Ache Laboratorios Farmaceuticos S.A.

Withdrawn

Evaluation of Efficacy and Safety in Control Cough and the Relief of Nasal Symptoms in Children 2-12 Years Old,Suffering From Cough and Acute Rhinitis

Inflammation | Cough | Rhinitis
Kite, A Gilead Company

Recruiting

Study of Axicabtagene Ciloleucel Versus Standard of Care Therapy in Participants With Relapsed/Refractory Follicular Lymphoma (ZUMA-22)

Relapsed/Refractory Follicular Lymphoma

United States, Spain, United Kingdom, Italy, France, Japan, Germany

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