Search clinical trials for: Lactated Ringer Solution

Total 21262 results

Merck Sharp & Dohme LLC

Active, not recruiting

Study of Pembrolizumab (MK-3475) Plus Chemotherapy vs Placebo Plus Chemotherapy as Neoadjuvant Therapy and Pembrolizumab vs Placebo as Adjuvant Therapy in Participants With Triple Negative Breast Cancer (TNBC) (MK-3475-522/KEYNOTE-522)

Triple Negative Breast Neoplasms

Brazil, Canada, United States, United Kingdom, Taiwan, Australia, Colombia, France, Germany, Ireland, Israel, Italy, Japan, Korea, Republic of, Poland, Portugal, Russian Federation, Singapore, Spain, Sweden, Turkey
Fondazione IRCCS Istituto Nazionale dei Tumori,...
Regione Lombardia

Active, not recruiting

Multidisciplinary Approach for Poor Prognosis Sinonasal Tumors in Inoperable Patients

Unresectable Sinonasal Tumors

Italy
Fondazione IRCCS Istituto Nazionale dei Tumori,...
Regione Lombardia

Active, not recruiting

Multidisciplinary Approach for Poor Prognosis Sinonasal Tumors in Operable Patients

Sinonasal Tumors

Italy
Sanofi
Regeneron Pharmaceuticals

Completed

Effect of Sarilumab on Patient-reported Outcomes in Patients With Active Rheumatoid Arthritis (SariPRO)

Rheumatoid Arthritis

France
Washington University School of Medicine

Completed

PECS Block vs. Multimodal Analgesia for Prevention of Persistent Postoperative Pain in Breast Surgery

Breast Cancer | Breast Cancer Female | Cancer of Breast

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
ZonMw: The Netherlands Organisation for Health Research and Development; Dutch...

Completed

Adjuvant HIPEC in High Risk Colon Cancer (COLOPEC)

Colorectal Neoplasms | Peritoneal Neoplasms

Netherlands
Jagiellonian University

Completed

Large Doses of Methylprednisolone Combined With Gabapentin in Total Knee Arthroplasty

Pain, Postoperative | Knee Osteoarthritis | Arthroplasty Complications | Perioperative Complication

Poland
Yeditepe University

Completed

Pain Relief During Intravenous Cannulation in Pediatric Patients

Local Anesthesia | Cannula Site Pain

Turkey
University of Jordan

Completed

Sedation and Analgesia Using PFK Versus General Anesthesia in Urological Procedures

Urologic Diseases | Anesthesia

Jordan
Genentech, Inc.

Completed

A Study to Investigate the Effect of Itraconazole and Rifampin on Pharmacokinetics (PK) of Vemurafenib at Steady State

Metastatic Melanoma, BRAF V600 Mutation Positive

Korea, Republic of, Russian Federation, Israel, United States
Abd-Elazeem Abd-Elhameed Elbakry

Completed

Dexmedetomidine and Pregabalin for Conscious Sedation During Cataract Surgery

Conscious Sedation

Egypt
Centre Hospitalier Universitaire de la Réunion

Withdrawn

Epidural Dexamethasone for Labor Analgesia: the Effects on Ropivacaine Consumption and Labour Outcome (DEXAPER)

Obstetric Pain | Other Complications of Obstetric Anesthesia - Delivered
Chemische Fabrik Kreussler & CO GmbH
Anfomed GmbH

Completed

Acceptance and Preference of Lidocaine Gel Compared to Injection Anesthesia After Non Surgical Periodontal Treatment

Periodontitis

Germany
Washington University School of Medicine
National Institute on Aging (NIA)

Completed

Role of Nitric Oxide in the Impact of Aging on Myocardial Remodeling

Cardiovascular Diseases

United States
Aciont Inc
National Eye Institute (NEI)

Completed

Safety and Efficacy Study of DSP-Visulex for the Treatment of Anterior Uveitis

Non-Infectious Anterior Uveitis

United States
Aeovian Pharmaceuticals, Inc.

Recruiting

Assessment of the Safety, Tolerability and Pharmacokinetics of AV078 in Healthy Volunteers

Healthy Participants

Australia
Aretaieion University Hospital

Recruiting

Opioid-free Anesthesia in Laparoscopic Cholecystectomies

Pain, Postoperative | Analgesia | Pain, Acute | Ketamine | Dexmedetomidine | Pain, Chronic | Cholecystectomy | Lidocaine | Central Nervous System Depressants | Analgesics | Analgesic Non-narcotic

Greece
Cerevel Therapeutics, LLC

Completed

A Trial to Evaluate the Effects of Itraconazole and Carbamazepine on the Pharmacokinetics of Emraclidine and of Emraclidine on the Pharmacokinetics of Metformin in Healthy Adult Participants

Healthy Volunteers

United States
Institut National de la Santé Et de la Recherche...

Completed

Trial of Treatments for COVID-19 in Hospitalized Adults (DisCoVeRy)

Corona Virus Infection

Norway, Austria, France, Greece, Portugal, Belgium, Luxembourg
Yuzuncu Yıl University

Completed

Comparison of the Effects of Dexamethasone and magnesıum Sulphate Used as Adjuvant in Infraclavicular Nerve Block.

Dexamethasone | Adjuvant | Bupivacaine | Magnesıum Sulphate

Turkey
R-Pharm International, LLC
IQVIA RDS Ireland Ltd; Thermo Fisher Scientific FS

Completed

Study in Subjects With Rheumatoid Arthritis to Evaluate the Effect of a Single Dose of Olokizumab on the Pharmacokinetics of Substrates for CYP1A2, CYP2C9, CYP2C19 and CYP3A4

Rheumatoid Arthritis

Bulgaria, Moldova, Republic of
Merck Sharp & Dohme LLC

Completed

A Study of Pembrolizumab (MK-3475) in Combination With Chemotherapy or Immunotherapy in Participants With Non-small Cell Lung Cancer (MK-3475-021/KEYNOTE-021)

Non-small Cell Lung Carcinoma
Sunshine Lake Pharma Co., Ltd.

Active, not recruiting

A Study to Evaluate Drug-Drug Interaction of Larotinib With Itraconazole and Rifampin in Healthy Adult Participants (Z650)

Healthy Volunteers

China
Michael Hoelscher
Radboud University Medical Center; German Federal Ministry of Education and... and other collaborators

Completed

BTZ-043 - Multiple Ascending Dose (MAD) to Evaluate Safety, Tolerability and Early Bactericidal Activity (EBA)

Pulmonary Tuberculoses | Other Specified Pulmonary Tuberculosis

South Africa
University of Monastir

Completed

Treatment of Renal Colic in the Emergency Departement (ED).

Renal Colic

Tunisia
Rhonda Brand
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Development of a Urine-Based Point-of-Care Test for Adherence to Antiretroviral Drugs (APTAMER)

HIV | Medication Adherence

United States
Millennium Pharmaceuticals, Inc.

Completed

A Study to Evaluate Drug-Drug Interaction of TAK-788 With Itraconazole and Rifampin in Healthy Adult Participants

Healthy Volunteers

United States
Children's Hospital Medical Center, Cincinnati
Bill and Melinda Gates Foundation; Syngene International

Completed

India Dexamethasone and Betamethasone

Preterm Birth | Antenatal Corticosteroids

India
Agios Pharmaceuticals, Inc.

Completed

Study to Evaluate the Effect of Multiple Doses of Itraconazole and Rifampin on the Single-Dose Pharmacokinetics of Mitapivat Sulfate (AG-348) in Healthy Adult Participants

Healthy Volunteers

United States
University of Pecs
Medical University of Pecs

Completed

Comparison of the Onset Times and Durations of Actions of Different Local Anesthetic Mixture Solutions [CODLAM] (CODLAM)

Injury Arm
Bristol-Myers Squibb

Completed

A Study to Evaluate the Effect of 2 Drugs on the Pharmacokinetics of BMS-986205 in Healthy Subjects

Malignancies Multiple

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Efficacy, Safety, and Tolerability of Dupilumab in Patients With Persistent Moderate to Severe Eosinophilic Asthma

Asthma

United States
University of Parma

Completed

Ultrasound-Guided Axillary or Infraclavicular Nerve Block for Upper Limb Surgery

Trauma | Forearm Injuries | Orthopedic Surgery | Nerve Block | Upper Extremity

Italy
National Institutes of Health Clinical Center (CC)

Completed

Impact of Weekly Administration of Rifapentine and Isoniazid on Steady State Pharmacokinetics of Tenofovir Alafenamide in Healthy Volunteers (YODA)

Healthy Volunteers

United States
Hebei Medical University Fourth Hospital

Recruiting

Dalpiciclib Plus AI (Neoadjuvant Endocrine Therapy) Compared With Neoadjuvant Chemotherapy in Early Breast Cancer （EBC）

Breast Cancer

China
Sociedad Andaluza de Enfermedades Infecciosas

Completed

Evaluation of Three Regimens of Chemoprophylaxis for Tuberculosis in Patients co-Infected by HIV and Mycobacterium Tuberculosis

HIV Infections

Spain
Jennifer Holder-Murray
Berry Consultants

Recruiting

Recommendations of Enhanced Recovery Interventions for Patient's Clinical Team and Collection of Associated Data

Perioperative Optimization

United States
Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Completed

Chemotherapy Combined With Radiation Therapy for Newly Diagnosed CNS AT/RT

Central Nervous System Tumor, Pediatric

United States
Yale University
National Center for Complementary and Integrative Health (NCCIH); Brain & Behavior...

Completed

Vitamin D as a Therapeutic Adjunct in the Stimulant Treatment of ADHD

ADHD

United States
Menarini International Operations Luxembourg SA

Completed

Intensive Urate Lowering Therapy of Febuxostat Compared to Allopurinol on Cardiovascular Risk in Patients With Gout (FORWARD)

Gout

Poland, Serbia, Germany, Italy, Netherlands, Romania
Roswell Park Cancer Institute
Celldex Therapeutics

Completed

DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Poly ICLC, Decitabine, and Nivolumab in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia

Acute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | High Risk Myelodysplastic Syndrome | Refractory Anemia | Blasts 30 Percent or Less of Bone Marrow Nucleated Cells

United States
Makerere University

Unknown

Evaluation of the Pharmacokinetics of Antituberculosis Drugs and Tuberculosis Treatment Outcomes (SOUTH)

AIDS With Tuberculosis

Uganda
GlaxoSmithKline
Bill and Melinda Gates Foundation; Wellcome Trust; Biomedical Advanced Research... and other collaborators

Recruiting

A Study to Evaluate Safety, Reactogenicity, and Immune Response of GVGH iNTS-TCV Vaccine Against Invasive Nontyphoidal Salmonella and Typhoid Fever

Salmonella Infections

Belgium, Malawi
Sinovac Research and Development Co., Ltd.

Active, not recruiting

Lot-to-lot Consistency of an Inactivated SARS-CoV-2 Vaccine Between Different Workshops in Healthy Children Aged 3-17 Years

COVID-19

China
Italfarmaco

Completed

Perpetrator DDI Potential of Givinostat as Inhibitor and Inducer of CYP3A and P-gp Activity

Drug-Drug Interaction

Portugal
GlaxoSmithKline

Completed

A Cross-over Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics (PK) of GSK525762 in Healthy Female Subjects of Non Child Bearing Potential

Neoplasms | Drug Interactions

United States
Dar El Oyoun Hospital

Unknown

Subconjunctival Atropine and Intracameral Epinephrine for Pupil Dilation in Phacoemulsification

Cataract | Adverse Drug Event | Mydriasis

Egypt
Ain Shams University

Recruiting

Comparing the Effect of Different Intracanal Dressing on Failed Root Canal Treated Cases on Periapical Healing

Periapical Disease

Egypt
Sanofi

Recruiting

A Prospective Study to Investigate Safety and Tolerability of Shorter Infusion of Fabrazyme (SHORTEN)

Fabry's Disease

United States
Sanofi Pasteur, a Sanofi Company

Completed

Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccine Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers

Healthy Volunteers (Meningococcal Infection)

United States, Puerto Rico

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