Search clinical trials for: Lipopolysaccharide challenge

Total 606 results

National Jewish Health

Not yet recruiting

Nasal Inflammation Following Endotoxin Challenge in Patients With Asthma (Nasal-LPS)

Asthma | Asthma; Eosinophilic

United States
GlaxoSmithKline
Professor Chilvers, University of Cambridge

Completed

Neutrophil Imaging in Healthy Subjects Following Lipopolysaccharide or Saline Challenge and in Subjects With Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Imperial College London; University of Manchester

Unknown

The Effect of Extrinsic Factors on Food Allergy (Ex-Factor)

Peanut Hypersensitivity

United Kingdom
Yale University

Completed

Neuroimmune Response to Lipopolysaccharide

Healthy

United States
Yale University
National Institute of Mental Health (NIMH)

Active, not recruiting

Imaging the Neuroimmune System in PTSD

Post Traumatic Stress Disorder

United States
Karolinska Institutet
The Swedish Research Council; University of California, San Francisco; Swedish... and other collaborators

Completed

Inflammation and Brain Function - Main Study

Sickness Behavior
John Sundy

Terminated

Genetics of Asthma - Bronchoscopy Studies

Healthy | Atopic Asthma

United States
Patrick Wagner, MD, FACS
List Biological Laboratories, Inc

Recruiting

Feasibility Study of Intra-Tumoral Lipopolysaccharide Immunotherapy for Intra-Abdominal (LPS)

Abdominal Cancer | Malignancy

United States
Radboud University Medical Center

Completed

The Effects of Concentration/Meditation on the Innate Immune Response During Human Endotoxemia

Innate Immune Response

Netherlands
Karolinska Institutet
The Swedish Research Council; University of California, San Francisco; Swedish... and other collaborators

Completed

Inflammation and Brain Function - Pilot Study

Sickness Behavior
Radboud University Medical Center
Exponential Biotherapies Inc.

Completed

PK/PD of EA-230 During Endotoxemia

Endotoxemia | Systemic Inflammatory Response

Netherlands
Radboud University Medical Center

Completed

Concentration/Meditation Limits Inflammation

Autoimmune Diseases

Netherlands
Radboud University Medical Center

Completed

Effects of Oxygen Status on Endotoxemia Induced Inflammation and Hypoxia Inducible Factor-1α

Hypoxia | Hyperoxia | Normoxia

Netherlands
Karolinska Institutet
Danderyd Hospital

Completed

Endotoxin-induced Inflammatory and Behavioral Responses and Predictors of Individual Differences

Sickness Behavior
Lund University
Food for Health Science Centre, Lund University

Completed

Acute Effects of Spices on Pathways Associated With Glucose Homeostasis and Inflammation on PBMCs of Healthy Subjects

Healthy

Sweden
Joslin Diabetes Center
ImmusanT, Inc.

Completed

Gluten Immunity and Islet Autoimmunity in Type-1 Diabetes

Type 1 Diabetes | Celiac Disease

United States
Hospital Mutua de Terrassa

Completed

Lymphocytic Enteritis and Suspected Coeliac Disease: Gluten vs Placebo

Celiac Disease | Non-celiac Gluten Sensitivity
Mahidol University

Completed

The Utility of Serum Tryptase in the Diagnosis of Shrimp- Induced Anaphylaxis

Food (Shrimp) Allergy

Thailand
Emory University
Centers for Disease Control and Prevention

Completed

The Mixed Meal Challenge Study

Cardiovascular Diseases | Hyperlipidemias

United States
University of North Carolina, Chapel Hill
Environmental Protection Agency (EPA)

Completed

Systemic Inflammatory Response to CCRE (Endoscreen)

Healthy

United States
Virginia Commonwealth University

Completed

Chronobiology of Meal Timing: Effects on Vascular and Renal Function

Hypertension

United States
GlaxoSmithKline
Biomedical Advanced Research and Development Authority

Terminated

Effects of GSK2798745 on Alveolar Barrier Disruption in a Segmental Lipopolysaccharide (LPS) Challenge Model

Healthy Volunteers

Germany
Hospices Civils de Lyon

Recruiting

A Net Ultrafiltration Challenge to Predict Preload-dependence (UF CHALLENGE) (UF CHALLENGE)

Acute Kidney Injury

France
The University of Texas Health Science Center,...

Recruiting

Identifying Correlates of Brain Microglial Activation in Neuropsychiatric Syndromes: A Dimensional Approach

Neuropsychiatric Syndromes

United States
McMaster University
St. Joseph's Healthcare Hamilton

Unknown

Effect of Allergen Challenge on Inflammation Induced by Toll-like Receptor Stimulation in a Nasal Model

Asthma

Canada
University of Palermo
Aurelio Seidita

Recruiting

Dietary Approach to Mild-to-moderate Psoriasis

Psoriasis | Gluten Sensitivity

Italy
Radboud University Medical Center
UMC Utrecht

Completed

The Effects of Human Endotoxemia on Functional Capacity of Hematopoietic Stem and Progenitor Cells (LPS-BM)

Sepsis, Endotoxemia, Immunosuppression

Netherlands
Fraunhofer-Institute of Toxicology and Experimental...
Hannover Medical School

Completed

Study to Assess the Effect of "Eucerin AtopiControl" on Dermal Symptoms in Patients With Atopic Dermatitis

Atopic Dermatitis | Allergy Pollen

Germany
National Jewish Health

Recruiting

Alveolar Macrophage Programming Following Endotoxin Exposure

ARDS, Human

United States
American University

Completed

Examining Outcome Expectancies and Behavioral Reinforcers Among Young Adult Smokers

Smoking Cessation

United States
University of Maryland, Baltimore
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Challenge! Adolescent Obesity Prevention (Challenge)

Obesity | Overweight

United States
Laureate Institute for Brain Research, Inc.

Completed

Lipopolysaccharide (LPS) Challenge in Depression

Major Depressive Disorder

United States
Boehringer Ingelheim

Completed

Effect of Single Oral Dose BIRB 796 BS on Endotoxin-induced Inflammatory Responses in Healthy Human Subjects

Healthy
University of Exeter

Recruiting

Molecular Imaging of Inflammation in Parkinson's Disease Using LPS and TSPO-PET/MR

Parkinson Disease | Neurodegenerative Diseases

United Kingdom
University of California, Davis

Completed

Predicting Fluid Responsiveness Using Transiently Increased Intrathoracic Pressure in Mechanically Ventilated Patients

Fluid Reponsiveness

United States
National Institute of Allergy and Infectious Diseases...

Completed

PfSPZ Challenge in Non-immune Adults in Baltimore, USA

Plasmodium Falciparum Infection

United States
Yale University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Recruiting

Effect of Endotoxin on Alcohol Consumption

Alcohol Use Disorder

United States
Kaiser Permanente
National Institute of Mental Health (NIMH)

Recruiting

Novel Methods for Implementing Measurement-Based Care for Youth in Low-resource Environments (NIMBLE)

Mental Health

United States
Rutgers, The State University of New Jersey

Completed

Inflammation and the Host Response to Injury (In Healthy Volunteers) (Mono)

Immune System

United States
Pontificia Universidad Catolica de Chile
Fondo Nacional de Desarrollo Científico y Tecnológico, Chile

Not yet recruiting

Capillary Refill Time Response to a Rapid Fluid Challenge in Septic Shock Patients (AUSTRALIS)

Septic Shock

Chile
Oslo University Hospital
Helse Sor-Ost; Stiftelsen Helse og Rehabilitering

Recruiting

Gluten Challenge in Celiac Disease

Celiac Disease

Norway
Emory University
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

Mental Stress and Myocardial Ischemia After MI: Sex Differences, Mechanisms and Prognosis (MIMS3)

Myocardial Infarction

United States
Ali A Abdulkareem

Active, not recruiting

The Potential Association of Long Non-coding RNA (NEAT1 and MALAT1) in the Process of Epithelial-mesenchymal Transition in Periodontitis

Epithelial Mesenchymal Transition | Periodontal Disease, AVDC Stage 3and 4 | Long Noncoding RNA

Iraq
University of North Texas, Denton, TX

Completed

Examining the Impact of an Online, Non-restrictive Diet Among Persons With Multiple Sclerosis

Multiple Sclerosis

United States
Centre Hospitalier Universitaire, Amiens
Centre Hospitalier Universitaire Dijon

Active, not recruiting

Comparison of 250 ml Versus 500 ml of Fluid Challenge (KOBIAS)

Oxygen Consumption | Critical Care | Fluid Challenge

France
Erasme University Hospital

Terminated

Fluid Challenges and Microcirculation (FC)

Surgery

France
Janssen Research & Development, LLC

Completed

A Study Exploring the Use of Challenge Agents in Healthy Volunteers or Participants With a Disease of Interest

Healthy

Belgium
Swinburne University of Technology
University of Sydney; University of Manchester; Brigham Young University

Completed

Evaluation of the Nextdoor KIND Challenge

Loneliness | Social Isolation

Australia
Humanitas Clinical and Research Center

Completed

Fluid Challenge Infusion and Response (REFILL)

Anesthesia, General | Cardiovascular System | Neurosurgery

Italy
Central Hospital, Nancy, France

Unknown

Fluid REsponsiveness and Arterial ELASTANCE in Patients With Septic Shock or After Aortic Surgery (RELASTANCE)

Shock, Septic | Aortic Stenosis | Oliguria | Aortic Aneurysm, Abdominal | Hyperlactatemia | Aortic Aneurysm, Ruptured

France

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