Search clinical trials for: Local anesthesia (buccal)

Total 13052 results

Universiti Kebangsaan Malaysia Medical Centre
Institue of Microengineering and Nanoelectronics (IMEN), Universiti Kebangsaan... and other collaborators

Completed

Efficacy of Transdermal Microneedle Patch for Topical Anesthesia Enhancement in Paediatric Thalassemia Patients

Thalassemia in Children

Malaysia
Tanta University

Completed

Pediatric Postoperative Analgesia With Quadratus Lumborum Block(QLB) And Dexamethasone As An Adjuvant To Bupivacaine. (QLB)

Abdominal Surgery | Post Operative Pain | Quadratus Lumborum Block | Pediatric

Egypt
Rush University Medical Center

Withdrawn

Multimodal Analgesia in Shoulder Arthroplasty

Shoulder Pain | Opioid Use

United States
Gil Yosipovitch

Terminated

Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocaine

Pruritus

United States
Mayo Clinic

Completed

The Effect of Intranasal Vasoconstrictor Medications on Hemodynamic Parameters: A Randomized Double-blind, Placebo-controlled Trial.

Blood Pressure | Epistaxis

United States
Shanghai Zhongshan Hospital

Unknown

Multimodal Analgesia Versus Traditional Opiate Based Analgesia

Cardiac Surgery
St Stephens Aids Trust
United States Agency for International Development (USAID); Mylan Inc.

Unknown

Pharmacokinetics of Efavirenz in the Presence of Rifampicin and Isoniazid

HIV

Uganda, United Kingdom
Ache Laboratorios Farmaceuticos S.A.

Withdrawn

Evaluation of Efficacy and Safety in Control Cough and the Relief of Nasal Symptoms in Children 2-12 Years Old,Suffering From Cough and Acute Rhinitis

Inflammation | Cough | Rhinitis
Food and Drug Administration (FDA)
Spaulding Clinical Research LLC

Completed

Ability of Late Sodium or Calcium Current Block to Balance the ECG Effects of Potassium Current Block

Pharmacokinetics | Pharmacodynamics | Drug-induced QT Prolongation
University of Aarhus
Aarhus University Hospital; AP Moeller Foundation; Bendtsen, Thomas Fichtner,...

Completed

Shamrock - Ultrasound/MR Image Fusion Guided Lumbar Plexus Block

Pain, Postoperative | Anesthesia, Local | Hip Fractures
University of Florida

Completed

Histamine Glutamate Antagonism in Stroke

Cerebral Edema | Acute Cerebrovascular Accident

United States
Jose Antonio Bernia Gil

Completed

Effectiveness of Analgesia in Total Knee Arthroplasty (ATR-2011)

Pain

Spain
Kyle A Perry

Completed

Reletex Versus Standard of Care Therapy for Post-Operative Nausea Control in Patients Undergoing Foregut Surgery (Reletex)

Nausea and Vomiting Post-foregut Surgery

United States
Isfahan University of Medical Sciences

Completed

Morphine Mouthwash for Management of Oral Mucositis in Patients With Head and Neck Cancer

Stomatitis

Iran, Islamic Republic of
Scott and White Hospital & Clinic

Completed

Effectiveness Study of Different Local Anesthetic Mixtures (CA)

Pain

United States
TYK Medicines, Inc

Completed

A Study to Assess the Effect of Food on the Pharmacokinetics of TY-9591 in Healthy Volunteers

Healthy Volunteers

China
Eurofarma Laboratorios S.A.

Not yet recruiting

Study of Fluticasone/Formoterol/Glycopyrronium for the Treatment Chronic Obstructive Pulmonary Disease (TRIPLAR) (TRIPLAR)

Chronic Obstructive Pulmonary Disease

Brazil
University Hospital, Angers

Recruiting

Study to Improve OS in 18 to 60 Year-old Patients, Comparing Daunorubicin Versus High Dose Idarubicin Induction Regimens, High Dose Versus Intermediate Dose Cytarabine Consolidation Regimens, and Standard Versus MMF Prophylaxis of GvHD in Allografted Patients in First CR (BIG-1)

Acute Myeloid Leukemia (AML)

France
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Pharmacokinetic Study to Evaluate the Drug Interaction Between HRS5091 and Probe Drugs in Healthy Volunteers

Chronic Hepatitis B

China
Rigshospitalet, Denmark
Glostrup University Hospital, Copenhagen

Completed

The Effect of Intraoperative Ketamine on Opioid Consumption and Pain After Spine Surgery in Opioid-dependent Patients

Chronic Pain | Postoperative Pain | Analgesics

Denmark
Seoul National University Hospital

Completed

Evaluation and Validation of Metabolic Markers for the Assessment of CYP3A Activity and Prediction of DDI (CYP3A_weak)

Healthy
First Affiliated Hospital of Harbin Medical University

Unknown

The Effect of Parecoxib Sodium Intravenous Patient-controlled Analgesia in Laparotomic Liver Resection

Pain, Postoperative

China
Repros Therapeutics Inc.

Completed

Open-Label, Multiple-Dose, Non-Randomized Study to Assess Drug-Drug Interactions of Proellex® in Female Subjects

Drug Interactions

United States
Magna Pharmaceuticals, Inc.

Unknown

StahistRx Phase 2, Five-arm, Parallel Group, Active vs Active, Double-blind Study

Rhinitis, Seasonal, Allergic

United States
AstraZeneca

Completed

Drug Interaction Study Between AZD3480 and Cytochrome P450 (Cocktail)

Alzheimer's Disease | Metabolism

Sweden
Cycle Pharmaceuticals Ltd.
FARMOVS Clinical Research Organisation

Completed

Bioequivalence Study of Two Oral Haloperidol Tablets Formulations in Healthy Subjects Under Fasting Conditions

Bioequivalence

South Africa
Beth Israel Deaconess Medical Center

Suspended

Avoiding Neuromuscular Blockers to Reduce Complications

Respiratory Failure | Aspiration Pneumonia | Atelectasis | Respiratory Infection | Bronchospasm | Pneumonitis

United States
Intarcia Therapeutics

Completed

Study of the Effects of ITCA 650 on Gastric Emptying and Interaction of ITCA 650 on 4 Commonly Studied Drugs

Healthy

United States
Cairo University

Recruiting

Methods Decreasing Bleeding in Open Myomectomy

Myoma | Blood Loss, Surgical | Misoprostol Allergy | Oxytocin Allergy | Tranexamic Acid Allergy | Ethamsylate Allergy

Egypt
Beni-Suef University

Not yet recruiting

Magnesium Sulphate Versus Ketamine as an Adjuvant to Bupivacaine in Pectoral Nerve Block During Mastectomy

Cancer | Breast

Egypt
Liaocheng People's Hospital

Recruiting

Susceptibility-Guided Sequential Therapy for Helicobacter Pylori Infection

Helicobacter Pylori Infection

China
University of Florida

Recruiting

Functional Endoscopic Sinus Surgery Study (FESS)

Chronic Rhinosinusitis (Diagnosis)

United States
University of Louisville

Recruiting

Auricular Acupuncture vs SOC in Migraine HA (MigAcu)

Migraine Headache

United States
Hoffmann-La Roche

Active, not recruiting

A Phase III, Non-Inferiority, Randomized, Open-Label, Parallel Group, Multicenter Study To Investigate The Pharmacokinetics, Pharmacodynamics, Safety And Radiological And Clinical Effects Of Subcutaneous Ocrelizumab Versus Intravenous Ocrelizumab In Patients With Multiple Sclerosis (Ocarina II)

Relapsing Multiple Sclerosis | Primary Progressive Multiple Sclerosis

Spain, United States, Italy, Poland, Turkey, New Zealand, Czechia, Brazil
TerSera Therapeutics LLC

Completed

Phase 2 Study IV QUZYTTIR™ (Cetirizine Hydrochloride Injection) vs V Diphenhydramine (versus)

Oncology Patients Receiving Chemotherapy

United States
Zagazig University

Completed

Suprascapular Nerve Block With Oral Gabapentin For Pain Management In Frozen Shoulder

Pain, Shoulder

Egypt
Fayoum University

Unknown

Efficacy Of Magnesium In Radicular Pain When Added To Local Anesthetics And Steroids In Transforaminal Epidural Injection

Pain | Neuropathy
Henlix, Inc

Completed

An Open-label, Phase 1 Study to Determine the Maximum Tolerated Dose of HLX07,in Patients With Advanced Solid Cancers

Solid Tumour

Taiwan, United States
Second Affiliated Hospital of Nanchang University

Unknown

Recombinant Bovine Basic Fibroblast Growth Factor for the Treatment of Radiation Induced Oral Mucositis

Stomatitis
National Institute of Allergy and Infectious Diseases...

Terminated

Controlled Clinical Trial of Antiviral Cytotoxic T Lymphocyte (CTL) Infusion Following Combination Antiretroviral Drug Therapy for Asymptomatic HIV-1 Infection

HIV Infections

United States
Johnson & Johnson Consumer and Personal Products...

Completed

Trial to Test if Antibiotic Ointments & Cream Will Sting After Application on a Minor Wound After Tape Stripping Injury

Sting
Klein, Jeffrey A., M.D.

Unknown

Tumescent Antibiotic Delivery for Prevention of Surgical Site Infection

Venous Thromboembolism | Surgical Site Infections
Mayo Clinic
National Center for Research Resources (NCRR)

Terminated

Epidural Clonidine for Lumbosacral Radiculopathy

Lumbar and Other Intervertebral Disc Disorders With Radiculopathy

United States
Aligos Therapeutics

Recruiting

A Study in Healthy Volunteers to Evaluate the Safety, Tolerability, Pharmacokinetics, and Drug-Drug Interaction Potential of Single and Multiple Doses of ALG-097558

COVID-19

United Kingdom
MODAG GmbH
Teva Pharmaceutical Industries, Ltd.; Quotient Sciences; Aptuit

Completed

A Drug-Drug Interaction Study to Assess the CYP1A2 and CYP3A4 Interaction Potential of TEV-56286 (anle138b)

Healthy Volunteers

United Kingdom
Biogen

Completed

An Open-Label Immunogenicity and Pharmacokinetics Study of Daclizumab High Yield Process Prefilled Syringe in Relapsing Remitting Multiple Sclerosis (OBSERVE)

Relapsing-Remitting Multiple Sclerosis

Poland, Hungary, United States, Czech Republic
Sylhet M.A.G.Osmani Medical College
University of Edinburgh

Completed

Adding Nebulized Salbutamol to Intravenous Atropine and Oxygen in OP Poisoning (SalbutamolOP)

Organophosphate Poisoning

Bangladesh
MinaPharm Pharmaceuticals

Unknown

Trial Comparing the Efficacy, Tolerability and Safety Between Three Arms in Treatment of HCV in Egyptian Population (Quadritherapy)

Chronic Hepatitis c

Egypt
St. Jude Children's Research Hospital

Recruiting

Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation

Acute Myeloid Leukemia (AML) | Acute Lymphoblastic Leukemia (ALL) | Myelodysplastic Syndrome (MDS) | Myeloid Sarcoma | Chronic Myeloid Leukemia (CML) | Non-Hodgkin Lymphoma (NHL) | Juvenile Myelomonocytic Leukemia (JMML)

United States
Spanish Breast Cancer Research Group
Merck Sharp & Dohme LLC

Completed

Incidence of Chemotherapy-Induced Nausea and Vomiting Associated With Docetaxel-Cyclophosphamide in Early Breast Cancer.

Breast Cancer

Spain

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