Search clinical trials for: MRA (Tocilizumab)

Total 6124 results

Hoffmann-La Roche

Completed

A Non-interventional Study of RoActemra/Actemra (Tocilizumab) in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Argentina
Hoffmann-La Roche

Completed

Efficacy and Safety Study of RoActemra (Tocilizumab) in Participants With Rheumatoid Arthritis

Rheumatoid Arthritis

Austria
Hoffmann-La Roche

Completed

An Open-label Study With Tocilizumab in Patients With Rheumatoid Arthritis in a Local Environment

Rheumatoid Arthritis

Tunisia
Chugai Pharmaceutical

Recruiting

A Phase 1 Study of SAIL66 in Patients With CLDN6-positive Locally Advanced or Metastatic Solid Tumors

Solid Tumor

United States, Japan
Tang-Du Hospital

Recruiting

Open-Label Extension of Tocilizumab in Subjects With Generalized Myasthenia Gravis (tMG-E)

Myasthenia Gravis, Generalized

China
University of Colorado, Denver
National Cancer Institute (NCI)

Recruiting

Tocilizumab in Children With ACP

Adamantinomatous Craniopharyngioma

United States
National Cancer Institute, Naples

Active, not recruiting

Tocilizumab in COVID-19 Pneumonia (TOCIVID-19) (TOCIVID-19)

COVID-19 Pneumonia

Italy
Genentech, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Tocilizumab in Hospitalized Participants With COVID-19 Pneumonia (EMPACTA)

COVID-19 Pneumonia

United States, Peru, Kenya, Mexico, Brazil, South Africa
Wenjie Zheng

Terminated

Tocilizumab for the Treatment of Refractory Behcet's Uveitis

Behcet Syndrome | Uveitis

China
Hoffmann-La Roche

Completed

Non-Interventional Study of Tocilizumab Subcutaneous (SC) Monotherapy in Participants With Rheumatoid Arthritis (RA) (SIMPACT)

Rheumatoid Arthritis

Hungary
University Hospital, Strasbourg, France

Completed

Efficacy of Tocilizumab in Primary Sjögren's Syndrome. (ETAP)

Primary Sjögren's Syndrome (pSS)

France
Hoffmann-La Roche
nv Roche sa

Completed

An Observational Study to Evaluate the Clinical Effectiveness, Quality of Life, Safety and Tolerability of Tocilizumab (TCZ) in Patients With Rheumatoid Arthritis (RA) in Daily Clinical Practice

Rheumatoid Arthritis

Belgium, Luxembourg
Papworth Hospital NHS Foundation Trust
Roche Pharma AG; National Institute for Health Research, United Kingdom

Completed

A Therapeutic Open Label Study of Tocilizumab in the Treatment of Pulmonary Arterial Hypertension (TRANSFORM-UK)

Pulmonary Arterial Hypertension

United Kingdom
Hoffmann-La Roche

Completed

A Phase IV Study to Evaluate the Effect of Subcutaneous (SC) Tocilizumab Administered to Participants With Rheumatoid Arthritis (RA) Assessed Using Disease Activity Score (DAS28)

Rheumatoid Arthritis

Slovakia
Hoffmann-La Roche

Completed

An Observational Study of Tocilizumab (Actemra) in Participants With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Peru
Hoffmann-La Roche
Clalit Health Services

Completed

Observational Study of RoActemra/Actemra (Tocilizumab) in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Israel
McMaster Children's Hospital

Withdrawn

Tocilizumab for Relapsing Polychondritis

Relapsing Polychondritis

Canada
National Institute of Allergy and Infectious Diseases...
PPD; Rho Federal Systems Division, Inc.; Immune Tolerance Network (ITN)

Completed

Tocilizumab (TCZ) in New-onset Type 1 Diabetes (EXTEND)

Type 1 Diabetes Mellitus | T1DM | T1D | New-onset Type 1 Diabetes Mellitus

United States, Australia
University Hospital of Patras

Completed

Tocilizumab Versus Baricitinib in Patients With Severe COVID-19

COVID-19

Greece
Peking Union Medical College Hospital

Completed

Pilot Study of Tocilizumab Monotherapy for Active Chronic Periaortitis

Chronic Periaortitis | Tocilizumab Monotherapy

China
Massachusetts General Hospital
Genentech, Inc.; Brigham and Women's Hospital

Terminated

Effect of Subcutaneous ACTEMRA on Inflamed Atherosclerotic Plaques in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis
Brigham and Women's Hospital

Terminated

Tocilizumab Augmentation in Treatment-Refractory Major Depressive Disorder

Major Depressive Disorder

United States
Hoffmann-La Roche

Completed

An Extension Study to Evaluate Long-Term Safety of Subcutaneous (SC) Tocilizumab in Participants With Giant Cell Arteritis (GCA)

Giant Cell Arteritis

France
University of Calgary

Unknown

Tocilizumab in Coronavirus-19 Positive Patients

COVID-19 | Inflammation | Covid19 | Coronavirus | Severe Acute Respiratory Syndrome Coronavirus 2
Medical College of Wisconsin

Terminated

Tocilizumab for Treatment of Steroid Refractory Acute Graft-versus-Host Disease

Acute Graft Versus Host Disease

United States
Eric B. Suhler
Genentech, Inc.

Terminated

Tocilizumab in the Management of Juvenile Idiopathic Arthritis Associated Uveitis

Juvenile Idiopathic Arthritis Associated Uveitis

United States
Hoffmann-La Roche

Completed

A Non-Interventional Study of Rheumatoid Arthritis Patients Treated With RoActemra/Actemra (Tocilizumab) in Monotherapy

Rheumatoid Arthritis

Belgium
University of Nebraska

Unknown

Study of the Safety, Tolerability, and Bioactivity of Tocilizumab On Patients With Non-infectious UVEITIS: The STOP-UVEITIS Study (STOP-Uveitis)

Posterior Uveitis | Intermediate Uveitis | Pan-uveitis

United States
National Cancer Institute (NCI)

Terminated

Tocilizumab for Patients With Cancer and COVID-19 Disease

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Pneumonia | Symptomatic COVID-19 Infection Laboratory-Confirmed | Severe Acute Respiratory Distress Syndrome | Pneumonitis

United States
Nationwide Children's Hospital
Children's Hospital Colorado

Recruiting

ACTEMRA® for the Treatment of Pediatric Adamantinomatous Craniopharyngioma

Adamantinomatous Craniopharyngioma | Recurrent Adamantinomatous Craniopharyngioma

United States, United Kingdom, Australia, Canada, Germany, Netherlands
Hoffmann-La Roche

Completed

An Extension Study of WA19926 of the Long-Term Safety of Tocilizumab (RoActemra/Actemra) in Patients With Early Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Russian Federation
Queen's Medical Center

Unknown

Trial of Tocilizumab for Treatment of Severe COVID-19: ARCHITECTS (ARCHITECTS)

COVID-19

United States
Karoline Krause
Roche Pharma AG

Completed

Tocilizumab in Patients With Schnitzler's Syndrome (TOCISCH)

Schnitzler's Syndrome

Germany
Hoffmann-La Roche

Completed

A Long Term Extension Study of WA19926 (NCT01007435) of Tocilizumab (RoActemra/Actemra) in Participants With Early, Moderate to Severe Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

Brazil
Hoffmann-La Roche

Terminated

An Extension Study to WA19977 in Patients With Active Polyarticular-Course Juvenile Idiopathic Arthritis

Juvenile Idiopathic Arthritis

Russian Federation, Poland
Keesler Air Force Base Medical Center

Completed

Short-Term Application of Tocilizumab Following Myocardial Infarction (STAT-MI)

Myocardial Infarction

United States
Hoffmann-La Roche

Completed

A Study of Tocilizumab in Patients With Rheumatoid Arthritis Who Have an Inadequate Response to Current Non-Biologic DMARDs

Rheumatoid Arthritis

Finland
Hoffmann-La Roche

Completed

A Study of Subcutaneously (SC) Administered Tocilizumab (TCZ) in Participants With Polyarticular-Course Juvenile Idiopathic Arthritis (pJIA) (JIGSAW 117)

Juvenile Idiopathic Arthritis

Spain, Mexico, Germany, United States, Russian Federation, Australia, Italy, Argentina, Brazil, Canada, France, United Kingdom
Hoffmann-La Roche

Completed

A Long-Term Extension Study of RoActemra/Actemra (Tocilizumab) in Patients With Juvenile Idiopathic Arthritis From France Who Completed WA19977 Core Study

Juvenile Idiopathic Arthritis

France
Hoffmann-La Roche

Completed

An Extension Long-Term Study of RoActemra/Actemra (Tocilizumab) in Patients With Polyarticular Juvenile Idiopathic Arthritis Who Completed The WA19977 Study

Juvenile Idiopathic Arthritis

Brazil
Hoffmann-La Roche

Completed

An Exploratory Study of Tocilizumab in Patients With Active Rheumatoid Arthritis (RA) and an Inadequate Response to Current Non-Biologic DMARDs and/or Anti-TNF Therapy.

Rheumatoid Arthritis

Belgium, Czech Republic, France, Italy, Spain, Sweden, United Kingdom, Canada, Greece, Ireland, Portugal, Turkey, Netherlands, Denmark, Finland, Germany, Luxembourg, Austria, Switzerland, Poland, Australia, Hungary, Saudi Arabia, Romania and more
Hoffmann-La Roche

Completed

A Study of Tocilizumab as Monotherapy or in Combination With DMARDs in Patients With Moderate to Severe Active Rheumatoid Arthritis

Rheumatoid Arthritis

United Arab Emirates, Kuwait, Bahrain, Iran, Islamic Republic of, Qatar
Tang-Du Hospital

Recruiting

Efficacy and Safety of Tocilizumab in the Treatment of Generalized Myasthenia Gravis (tMG)

Myasthenia Gravis, Generalized

China
Centre Hospitalier Régional d'Orléans
Rennes University Hospital

Recruiting

Filling Bone Erosions: a Longitudinal Multicentric HR-pQCT Study of Subcutaneous Tocilizumab in Rheumatoid Arthritis (REPAIR)

Rheumatoid Arthritis

France
Chester Oddis
Genentech, Inc.

Completed

Tocilizumab in the Treatment of Refractory Polymyositis and Dermatomyositis (TIM)

Dermatomyositis | Polymyositis

United States
Hoffmann-La Roche

Completed

A Study of Subcutaneously Administered Tocilizumab in Participants With Systemic Juvenile Idiopathic Arthritis

Juvenile Idiopathic Arthritis

United States, Canada, United Kingdom, Brazil, Argentina, Germany, Italy, Russian Federation, Spain, Mexico, Australia, France
Hoffmann-La Roche

Completed

A Study of RoActemra/Actemra (Tocilizumab) in Patients With Rheumatoid Arthritis Who Have an Inadequate Response to DMARDs or Anti-TNF

Rheumatoid Arthritis

Saudi Arabia
Hoffmann-La Roche

Completed

A Study to Assess the Effect of Tocilizumab on Signs and Symptoms in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Philippines
Hoffmann-La Roche

Completed

A Study of the Efficacy and Safety of Tocilizumab in Adults With Rheumatoid Arthritis.

Rheumatoid Arthritis

Israel
Hoffmann-La Roche

Completed

A Long-Term Extension Study of WA22762 to Evaluate Safety and Efficacy of Subcutaneous Tocilizumab in Participants With Moderate to Severe Rheumatoid Arthritis (RA).

Rheumatoid Arthritis

France

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