Search clinical trials for: Mechlorethamine

Total 103 results

Yaupon Therapeutics

Completed

Safety and Efficacy of Nitrogen Mustard in Treatment of Mycosis Fungoides

Mycosis Fungoides

United States
Yaupon Therapeutics

Completed

An Open Label Study to Evaluate the Safety and Efficacy of Mechlorethamine(MCH) 0.04% Formulation in Mycosis Fungoides

Mycosis Fungoides

United States
Mayo Clinic
Actelion

Completed

Valchlor in the Treatment of Lichen Planopilaris

Lichen Planopilaris

United States
Helsinn Therapeutics (U.S.), Inc

Completed

Clinical Study Assessing Outcomes, Adverse Events, Treatment Patterns, and Quality of Life in Patients Diagnosed With Mycosis Fungoides Cutaneous T-cell Lymphoma (PROVe)

Mycosis Fungoides

United States
Thomas Jefferson University
Actelion

Unknown

Low Dose Total Skin Electron Beam Treatment (TSEBT) Followed by Maintenance Valchlor for Patients With Mycosis Fungoides

Mycosis Fungoides | Cutaneous T-cell Lymphoma
Sidney Kimmel Cancer Center at Thomas Jefferson...
Actelion

Withdrawn

Low Dose Total Skin Electron Beam Radiation Therapy and Mechlorethamine Hydrochloride Gel in Treating Patients With Mycosis Fungoides

Mycosis Fungoides

United States
Rochester Skin Lymphoma Medical Group, PLLC
Rochester General Hospital

Completed

Mechlorethamine Induced Contact Dermatitis Avoidance Study (MIDAS)

Mycosis Fungoides | Cutaneous T-cell Lymphoma | Transformed Mycosis Fungoides | Cutaneous T-cell Lymphoma Stage I | Folliculotropic Mycosis Fungoides | Granulomatous Slack Skin | Syringotropic Mycosis Fungoides | Mycosis Fungoides Variant

United States
Centre for Human Drug Research, Netherlands
Recordati Rare Diseases

Completed

Deep Phenotyping of Cutaneous T Cell Lymphoma, Type Mycosis Fungoides

Mycosis Fungoides

Netherlands
Soligenix

Recruiting

HyBryte (Synthetic Hypericin) Versus Valchlor (Mechlorethamine) in the Treatment of CTCL

Cutaneous T-Cell Lymphoma/Mycosis Fungoides

United States
University of Copenhagen

Completed

Effects of a Specific Spice on Energy Metabolism

Healthy

Denmark
European Organisation for Research and Treatment...

Terminated

REACH: Study to Determine the Aetiology of Chlormethine Gel Induced-skin Drug Reaction in Early Stage Mycosis Fungoides Cutaneous T Cell Lymphoma (MF-CTCL) (REACH)

Early Stage Mycosis Fungoides Cutaneous T Cell Lymphoma (MF-CTCL) (Stage IA-IB)

France
University of Ulster
University of Reading; The James Hutton Institute

Completed

Broccoli Ileo Study

Ileostomy - Stoma

United Kingdom
Government College of Dentistry, Indore

Completed

To Study the Beneficial Effect of Mustard Oil and Salt Massaging With Oral Prophylaxis in Patients With Gum Diseases

Chronic Periodontitis

India
Stanford University
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Advanced Hodgkin's Lymphoma

Lymphoma

United States
Appalachian State University
Brassica Foundation for Chemoprotection Research

Completed

Broccoli Sulforaphane Bioavailability With Mustard

Sulforaphane Bioavailability

United States
ARCIM Institute Academic Research in Complementary...
University Hospital Tuebingen

Completed

Dose-response Relationship of Mustard Flour Footbaths in Healthy Volunteers

Thermogenesis by Different-dosage Mustard Flour Footbaths

Germany
Centro di Riferimento Oncologico - Aviano

Unknown

Combination Chemotherapy in Treating Patients With Hodgkin's Disease and HIV Infection

Lymphoma

Italy
Mount Vernon Cancer Centre at Mount Vernon Hospital

Unknown

Combination Chemotherapy in Treating Patients With Previously Untreated Advanced Hodgkin's Lymphoma

Lymphoma

United Kingdom
Stanford University
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Early-Stage Hodgkin's Disease

Lymphoma

United States
European Organisation for Research and Treatment...

Active, not recruiting

Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Previously Untreated Stage I or Stage II Hodgkin's Lymphoma

Lymphoma
Assistance Publique - Hôpitaux de Paris

Completed

Development of a New Non-radioactive Test for Measuring Glomerular Filtration Rate Using the Tetrapeptide N-acetyl-Ser-Asp-Lys-Pro-amide (AcSDKP-NH2) (AcSDKP-NH2)

Healthy | Chronic Kidney Disease

France
European Organisation for Research and Treatment...

Active, not recruiting

RT or No RT Following Chemotherapy in Treating Patients With Stage III/IV Hodgkin's Disease

Lymphoma

France, Poland, Belgium, Netherlands, Slovenia, Italy, Egypt, Portugal, Germany
University Hospitals Cleveland Medical Center
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Completed

Effect of Vitamin D After Application With Valchlor

Skin Irritation

United States
St. Jude Children's Research Hospital

Completed

Chemotherapy With Low-Dose Radiation for Pediatric Hodgkin Lymphoma

Hodgkin's Lymphoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Children With Astrocytomas and Primitive Neuroectodermal Tumors

Brain and Central Nervous System Tumors

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Intra-arterial Melphalan in Treating Younger Patients With Unilateral Retinoblastoma

Unilateral Retinoblastoma

United States
Case Comprehensive Cancer Center

Not yet recruiting

Triamcinolone Acetonide Injections in Primary Cutaneous Lymphoma Plaques With a Novel Needle-free Drug-delivery System.

Lymphoma, Follicular | Cutaneous T-cell Lymphoma | Non Hodgkin Lymphoma | Lymphoma, Large-Cell, Anaplastic | Lymphomatoid Papulosis | Mycosis Fungoides of Skin (Diagnosis)

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Secondary Acute Myeloid Leukemia | Myelodysplastic Syndrome | Minimal Residual Disease | Hematopoietic Cell Transplantation Recipient | Acute Myeloid Leukemia in Remission | Acute Lymphoblastic Leukemia in Remission

United States
University of Nebraska

Terminated

Enhancing Anti--Tetanus Vaccine Response After Autologous Stem Cell Transplantation

Plasma Cell Myeloma

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or High-Risk Primary Refractory Hodgkin Lymphoma

Lymphoma

United States
St. Jude Children's Research Hospital
CURE Childhood Cancer, Inc.

Completed

A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas

Melanoma | Lymphoma | Renal Cell Carcinoma | Ewing Sarcoma | Rhabdoid Tumor | Neuroblastoma | Rhabdomyosarcoma | Wilms Tumor | Germ Cell Tumor | Gastrointestinal Tumor | Hepatic Tumor | Clear Cell Carcinoma | Non-rhabdomyosarcoma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Daratumumab After Stem Cell Transplant in Treating Patients With Multiple Myeloma

Plasma Cell Myeloma | Secondary Amyloidosis

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Carfilzomib and Melphalan Before Stem Cell Transplant in Treating Patients With Multiple Myeloma

Refractory Plasma Cell Myeloma | DS Stage I Plasma Cell Myeloma | DS Stage II Plasma Cell Myeloma | DS Stage III Plasma Cell Myeloma

United States
St. Jude Children's Research Hospital

Recruiting

Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation

Acute Myeloid Leukemia (AML) | Acute Lymphoblastic Leukemia (ALL) | Myelodysplastic Syndrome (MDS) | Myeloid Sarcoma | Chronic Myeloid Leukemia (CML) | Non-Hodgkin Lymphoma (NHL) | Juvenile Myelomonocytic Leukemia (JMML)

United States
Roswell Park Cancer Institute

Active, not recruiting

Genetically Engineered Cells (NY-ESO-1 TCR Engineered T Cells and HSCs) After Melphalan Conditioning Regimen in Treating Patients With Recurrent or Refractory Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Platinum-Resistant Fallopian Tube Carcinoma | Platinum-Resistant Primary Peritoneal Carcinoma | Platinum-Resistant Ovarian Carcinoma | Platinum-Sensitive Ovarian Carcinoma | Refractory Ovarian... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Itacitinib, Tacrolimus, and Sirolimus for the Prevention of GVHD in Patients With Acute Leukemia, Myelodysplastic Syndrome, or Myelofibrosis Undergoing Reduced Intensity Conditioning Donor Stem Cell Transplantation

Primary Myelofibrosis | Acute Leukemia | Myelodysplastic Syndrome | Secondary Myelofibrosis | Hematologic and Lymphocytic Disorder

United States
St. Jude Children's Research Hospital

Completed

Mismatched Family Member Donor Transplantation for Children and Young Adults With High Risk Hematological Malignancies

Hodgkin Lymphoma | Myelodysplastic Syndrome (MDS) | Leukemia, Acute Lymphocytic (ALL) | Juvenile Myelomonocytic Leukemia (JMML) | Leukemia, Myeloid, Acute(AML) | Leukemia, Myeloid, Chronic(CML) | Hemoglobinuria, Paroxysmal Nocturnal (PNH) | Lymphoma, Non-Hodgkin (NHL)

United States
St. Jude Children's Research Hospital
Assisi Foundation

Completed

Haploidentical Donor Hematopoietic Progenitor Cell and NK Cell Transplantation for Hematologic Malignancy

Lymphoma | Leukemia

United States
National Cancer Institute (NCI)

Withdrawn

RO4929097 After Autologous Stem Cell Transplant in Treating Patients With Multiple Myeloma

Refractory Plasma Cell Myeloma | DS Stage I Plasma Cell Myeloma | DS Stage II Plasma Cell Myeloma | DS Stage III Plasma Cell Myeloma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Umbilical Cord Blood-Derived Natural Killer Cells, Elotuzumab, Lenalidomide, and High Dose Melphalan, Followed by Stem Cell Transplant in Treating Patients With Multiple Myeloma

Plasma Cell Myeloma | Plasma Cell Leukemia

United States
St. Jude Children's Research Hospital

Terminated

Repeat Transplantation for Relapsed or Refractory Hematologic Malignancies Following Prior Transplantation

Acute Myeloid Leukemia (AML) | Acute Lymphoblastic Leukemia (ALL) | Myelodysplastic Syndrome (MDS) | Myeloid Sarcoma | Chronic Myelogenous Leukemia (CML) | Non-Hodgkin Lymphoma (NHL) | Juvenile Myelomonocytic Leukemia (JMML)

United States
National Cancer Institute (NCI)

Active, not recruiting

Lenalidomide in Treating Patients With Multiple Myeloma Undergoing Autologous Stem Cell Transplant

Smoldering Multiple Myeloma | Refractory Multiple Myeloma | DS Stage I Multiple Myeloma | DS Stage II Multiple Myeloma | DS Stage III Multiple Myeloma

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Hodgkin's Lymphoma

Lymphoma

United States, Canada, South Africa
OHSU Knight Cancer Institute
National Institute of Neurological Disorders and Stroke (NINDS); Oregon Health...

Active, not recruiting

Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors

Medulloblastoma | Recurrent Malignant Germ Cell Tumor | Recurrent Medulloblastoma | Germ Cell Tumor | Primitive Neuroectodermal Tumor | Medulloepithelioma | Recurrent Primitive Neuroectodermal Tumor | Embryonal Tumor With Multilayered Rosettes, C19MC-Altered | Recurrent Childhood Central Nervous System... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Withdrawn

Radioimmunotherapy (211At-OKT10-B10) and Chemotherapy (Melphalan) Before Stem Cell Transplantation for the Treatment of Multiple Myeloma

Plasma Cell Myeloma

United States
Children's Oncology Group

Recruiting

A Study to Give Treatment Inside the Eye to Treat Retinoblastoma

Bilateral Retinoblastoma | Childhood Intraocular Retinoblastoma | Unilateral Retinoblastoma | Group D Retinoblastoma | Stage I Retinoblastoma

United States
St. Jude Children's Research Hospital

Completed

A Pilot Study of Immunotherapy Including Haploidentical NK Cell Infusion Following CD133+ Positively-Selected Autologous Hematopoietic Stem Cells in Children With High Risk Solid Tumors or Lymphomas

Lymphoma | Neuroblastoma | High-risk Tumor

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Withdrawn

Ruxolitinib Phosphate, Tacrolimus and Sirolimus in Preventing Acute Graft-versus-Host Disease During Reduced Intensity Donor Hematopoietic Cell Transplant in Patients With Myelofibrosis

Primary Myelofibrosis | Secondary Acute Myeloid Leukemia | Secondary Myelofibrosis | Acute Myeloid Leukemia in Remission | Primary Myelofibrosis, Prefibrotic Stage

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Ruxolitinib Phosphate and Chemotherapy Given Before and After Reduced Intensity Donor Stem Cell Transplant in Treating Patients With Myelofibrosis

Primary Myelofibrosis | Secondary Myelofibrosis

United States
St. Jude Children's Research Hospital

Terminated

Combined T Cell Depleted Haploidentical Peripheral Blood Stem Cell and Unrelated Umbilical Cord Blood Transplantation in Patients With Hematologic Malignancies Using a Total Lymphoid Irradiation Based Preparative Regimen

Hematological Malignancies

United States

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