Search clinical trials for: Metformin, glyburide and insulin

Total 4837 results

University of Texas Southwestern Medical Center

Completed

Preservation of Beta-cell Function in Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Fundació Institut de Recerca de l'Hospital de la...

Completed

Glyburide and Metformin for the Treatment of Gestational Diabetes Mellitus. Systematic Review

Gestational Diabetes Mellitus

Spain
Université de Sherbrooke
Fonds de la Recherche en Santé du Québec

Completed

Gestational Diabetes: Insulin or Oral Hypoglycemic Agents? (DG5)

Gestational Diabetes Mellitus

Canada
Regional Obstetrical Consultants

Unknown

Comparison of Glucovance to Insulin for Diabetes During Pregnancy

Pregnancy | Type 2 Diabetes | Gestational Diabetes

United States
Bristol-Myers Squibb

Completed

A Research Study to Determine the Safety and Efficacy of Glucovance Compared to Metformin and Glyburide in Children and Adolescents With Type 2 Diabetes.

Diabetes Mellitus, Non-Insulin-Dependent

United States
Maisa N. Feghali, MD

Completed

Metabolic Analysis for Treatment Choice in Gestational Diabetes Mellitus (MATCh-GDM)

Gestational Diabetes | Diabetes, Gestational | Pregnancy in Diabetes

United States
Bristol-Myers Squibb

Completed

A Research Study to Assess the Mechanism By Which Glucovance, Metformin, and Glyburide Work To Control Glucose Levels In Patients With Type 2 Diabetes

Diabetes Mellitus, Non-Insulin-Dependent

United States
GlaxoSmithKline

Completed

Diabetes Study With Rosiglitazone Monotherapy Versus Metformin Or Glyburide/Glibenclamide

Diabetes Mellitus, Type 2

United States, Germany, Canada, Belgium, Denmark, Spain, Ireland, Netherlands, United Kingdom, Hungary, Italy, France, Austria, Czechia, Norway, Finland, Sweden
Eunice Kennedy Shriver National Institute of Child...
University of Pittsburgh; University of Washington; University of Texas; RTI International and other collaborators

Unknown

Glyburide and Metformin for Gestational Diabetes Mellitus (GDM) (GDM)

Gestational Diabetes Mellitus

United States
Novo Nordisk A/S

Completed

Efficacy and Safety of Biphasic Insulin Aspart 30 With Metformin in Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

South Africa
Texas Tech University Health Sciences Center, El...

Terminated

Glyburide vs Glucovance in the Treatment of GDM (GGIG)

Gestational Diabetes

United States
Novo Nordisk A/S

Completed

Comparison of Biphasic Insulin Aspart 70/30, 50/50, and 30/70 in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Poland, United Kingdom, Spain, Denmark, France, Netherlands, Austria, Hungary, Russian Federation, Germany, Turkey, Italy, Bulgaria, Romania, Belgium, Switzerland, Slovenia, Czech Republic
Novo Nordisk A/S

Completed

Comparison of Insulin Glargine Versus Biphasic Insulin Aspart 30/70 or Biphasic Insulin Aspart 30/70 in Combination With Metformin in Subjects With Type 2 Diabetes.

Diabetes Mellitus, Type 2 | Diabetes

Turkey
Novo Nordisk A/S

Completed

Biphasic Insulin Aspart 30 in Type 2 Diabetes Failing OAD Therapy (INITIATE)

Diabetes Mellitus, Type 2 | Diabetes

United States
Novo Nordisk A/S

Completed

Efficacy and Safety of Metformin Plus Biphasic Insulin Aspart 30 in Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Argentina, Brazil
Novo Nordisk A/S

Completed

Comparison of Two NN5401 Formulations Versus Biphasic Insulin Aspart 30, All in Combination With Metformin in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Poland, Spain, Germany, Finland, France
Sanofi

Completed

Determine Whether Glycemic Control is Different Between Lantus & a 3rd Oral Agent When Failure With Other Treatment

Diabetes Mellitus

United States
University of Maryland, Baltimore

Not yet recruiting

Investigation of the Efficacy of Metformin Therapy on Pulmonary Sarcoidosis (MetforminTOP)

Sarcoidosis, Pulmonary
Sanofi

Completed

Insulin Glargine in Type 2 Diabetic Patients (TARGET)

Diabetes Mellitus, Type 2

China
Novo Nordisk A/S

Completed

Comparison of Biphasic Insulin Aspart 70/30 With Anti-Diabetic Drugs in Subjects With Type 2 Diabetes (ACTION)

Diabetes Mellitus, Type 2 | Diabetes

United States
Mount Sinai Hospital, Canada
Canadian Institutes of Health Research (CIHR)

Completed

Early Intermittent Intensive Insulin Therapy as an Effective Treatment of Type 2 Diabetes (RESET-IT Main Trial) (RESET-IT)

Type 2 Diabetes

Canada
Novo Nordisk A/S

Completed

Comparing the Efficacy and Safety of Biphasic Insulin Aspart 30 and Biphasic Human Insulin 30 on Blood Sugar Control in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

China
Novo Nordisk A/S

Completed

Effect of Biphasic Insulin Aspart 30 Combined With Metformin on Blood Glucose Control in Subjects With Type 2 Diabetes Inadequately Controlled With Basal Insulin

Diabetes Mellitus, Type 2 | Diabetes

China
Teva Pharmaceuticals USA

Completed

Glyburide/Metformin 5 mg/500 mg Film-Coated Tablets, Fed

Healthy

Canada
Novo Nordisk A/S

Completed

Effect of Different Insulin Administrations, All in Combination With Metformin, on Glycaemic Control in Subjects With Type 2 Diabetes Inadequately Controlled by Oral Anti-diabetic Drugs

Diabetes Mellitus, Type 2 | Diabetes

Morocco, Tunisia, Algeria, South Africa, Egypt
Teva Pharmaceuticals USA

Completed

Glyburide/Metformin 5 mg/500 mg Film-Coated Tablets, Fasting

Healthy

Canada
Novo Nordisk A/S

Completed

Comparison of Biphasic Insulin Aspart 30 Versus Insulin Glargine Both in Combination With Metformin and Glimepiride in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Poland, Spain, Sweden, Malaysia, France, Netherlands, India, Argentina, South Africa, Romania, Former Serbia and Montenegro, Austria, Czech Republic, Philippines, Mexico
Novo Nordisk A/S

Completed

Comparison of Biphasic Insulin Aspart 30 Twice Daily With Two Different Initial Dosage Split Regimens in Subjects With Type 2 Diabetes: An Extension to Trial BIASP-3756

Diabetes Mellitus, Type 2 | Diabetes

China
HaEmek Medical Center, Israel

Completed

A Comparison Between Two Oral Hypoglycemics - Metformin and Glybenclamide for the Treatment of Gestational Diabetes Mellitus

Gestational Diabetes Mellitus

Israel
Novo Nordisk A/S

Completed

Effect of Biphasic Insulin Aspart 50 on Blood Glucose Control in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

China
Actavis Inc.

Completed

A Relative Bioavailability Study of Glyburide/Metformin HCl 5 mg/500 mg Tablets Under Fasting Conditions

Healthy

United States
University of New Mexico

Completed

Metformin Compared to Glyburide in Gestational Diabetes

Gestational Diabetes

United States
Novo Nordisk A/S

Terminated

Efficacy and Safety of Insulin Aspart Versus Glibenclamide in Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes
Mannkind Corporation

Completed

Efficacy and Safety of Prandial Inhalation of Technosphere/Insulin in Combination With Metformin or Technosphere/Insulin Alone Versus 2 Oral Anti-Diabetic Agents in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, Brazil, Spain, Argentina, Canada, Chile, Mexico, Poland, Russian Federation, Ukraine, Czech Republic
Actavis Inc.

Completed

A Relative Bioavailability Study of Glyburide/Metformin HCl 5 mg/500 mg Tablets Under Non-fasting Conditions

Healthy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Glyburide/Metformin HCl 5 mg/500 mg Tablets Under Fasting Conditions

Healthy

United States
Takeda

Completed

Efficacy of Pioglitazone and Metformin on Cardiovascular Risk in Subjects With Insulin-Treated Type 2 Diabetes Mellitus. (PIOcomb)

Diabetes Mellitus

Germany
Assistance Publique - Hôpitaux de Paris

Completed

Multicenter Randomized Trial of Non-inferiority Between Glyburide and Insulin for the Treatment of Gestational Diabetes (INDAO)

Diabetes | Gestational

France
University Hospital, Toulouse

Completed

Efficacy of Continuous Subcutaneous Insulin Infusion Versus Basal-bolus Multiple Daily Injections Regimen in Type 2 Diabetes

Type 2 Diabetes Mellitus

France
Novo Nordisk A/S

Completed

Comparison of the Blood Sugar Lowering Effect of Biphasic Insulin Aspart 30 and Insulin Glargine Both Combined With Metformin and Glimepiride in Chinese and Japanese Subjects With Type 2 Diabetes New to Insulin Treatment (EasyMix)

Diabetes Mellitus, Type 2 | Diabetes

Japan, China
University of Edinburgh
Chief Scientist Office of the Scottish Government

Completed

A Feasibility Study Looking at the Use of Glibenclamide and metfoRmin Versus stAndard Care in gEstational diabeteS (GRACES)

Pregnancy | Gestational Diabetes

United Kingdom
The University of Texas Health Science Center,...

Withdrawn

Failure Rate of GLyburide And Metformin Among Gestational Diabetics (GLAM)

Gestational Diabetes Mellitus, Class A2
Novo Nordisk A/S

Completed

Comparison of Two NN1250 Formulations Versus Insulin Glargine, All in Combination With Metformin in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

United States, India, South Africa, Canada
Tripler Army Medical Center

Withdrawn

Glyburide Compared to Insulin in the Management of White's Classification A2 Gestational Diabetes

Gestational Diabetes

United States
The University of Texas Health Science Center at...
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); American... and other collaborators

Completed

Durability of Combination Therapy With Exenatide/Pioglitazone/Metformin vs. Conventional Therapy in New Onset T2DM

Diabetes

United States
University of Jordan

Completed

Dosage Reduction and Acute Glycemic Complications in People With Type 2 Diabetes Who Fast During Ramadan

Diabetes Mellitus, Type 2

Jordan
Eli Lilly and Company

Completed

Long-Term Effects of Insulin Plus Metformin Regimens on the Overall and Postprandial Glycemic Control of Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, Australia, Greece, India, Netherlands, Poland, Puerto Rico
Mount Sinai Hospital, Canada
Canadian Institutes of Health Research (CIHR)

Completed

Early Intermittent Intensive Insulin Therapy as an Effective Treatment of Type 2 Diabetes (RESET-IT Pilot Study)

Type 2 Diabetes

Canada
Centre hospitalier de l'Université de Montréal...
Radiological Society of North America; Centre de Recherche du Centre Hospitalier... and other collaborators

Completed

Study of Liraglutide Versus Insulin on Liver Fat Fraction in Patients With Type 2 Diabetes (LIRAINS)

Type 2 Diabetes | Nonalcoholic Fatty Liver Disease | Nonalcoholic Steatohepatitis

Canada
ikfe-CRO GmbH
IKFE Institute for Clinical Research and Development

Completed

Beta-Cell Function of Insulin Glargine Compared to Neutral Protamine Hagedorn (NPH) Insuline and to Insulin Detemir in Combination With Metformin

Type 2 Diabetic Patients | Insufficient Metabolic Control | OAD Treatment

Germany

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