Search clinical trials for: Midazolam, Warfarin, Omeprazole, VitaminK1 and SHR3680

Total 230 results

Jiangsu HengRui Medicine Co., Ltd.

Completed

The DDI Study Had Been Designed to Investigate the Effect of SHR3680 on the Pharmacokinetics of Midazolam, S-Warfarin and Omeprazole

Prostate Cancer Patients

China
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Pharmacokinetic Study to Evaluate the Drug Interaction Between SHR0302 and CYP Substrates in Healthy Volunteers

Rheumatoid Arthritis

China
University of Alberta
Heart and Stroke Foundation of Canada; Canadian Stroke Prevention Intervention...

Completed

Improving Stroke Prevention in Atrial Fibrillation Through Pharmacist Prescribing (PIAAFRx)

Stroke | Atrial Fibrillation

Canada
Jiangsu HengRui Medicine Co., Ltd.

Completed

PK Effects of SHR4640 on Repaglinide and Midazolam, and the Impact of SHR4640 on QT Interval

Gout and Hyperuricemia

China
Jiangsu HengRui Medicine Co., Ltd.

Completed

Effect of Omeprazole on the Pharmacokinetics of SHR6390 in Healthy Subjects

Advanced Solid Tumor

China
Daiichi Sankyo, Inc.
Medpace, Inc.

Completed

Drug-drug Interaction Study of Tivantinib (ARQ 197) With Omeprazole, S-warfarin, Caffeine, Midazolam, and Digoxin in Cancer Subjects

Solid Tumors

United States
University of North Carolina, Chapel Hill

Completed

Mechanisms Underlying Drug-Diet Interactions

Pharmacokinetics

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Pharmacokinetic Study to Evaluate the Drug Interaction Between HRS5091 and Probe Drugs in Healthy Volunteers

Chronic Hepatitis B

China
Idorsia Pharmaceuticals Ltd.

Completed

Pharmacokinetics of Omeprazole and Midazolam When Co-administered With ACT-1014-6470

Healthy | Drug Drug Interaction

Czechia
Chinese University of Hong Kong
Professor Bryan Ping Yen YAN (byan)

Recruiting

Warfarin Dosage Adjustment Model Analysis Study

Warfarin

Hong Kong
Vivencio Barrios
Bayer

Completed

INR Control and Atrial Fibrillation in Primary Care in Spain (PAULA) (PAULA)

Atrial Fibrillation and Flutter
ARYx Therapeutics

Unknown

Comparison of ATI-5923, a Novel Vitamin K Antagonist, With Warfarin in Patients Requiring Chronic Anticoagulation (EmbraceAC)

Myocardial Infarction | Atrial Fibrillation | Atrial Flutter | Cardiomyopathy | Venous Thromboembolic Disease

United States
SK Life Science, Inc.

Completed

Assess the Influence of Cenobamate on the PK of Cytochrome P450 (CYP) Probe Drugs as a Means of Predicting Drug-drug Interactions

Healthy

United States
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

A Study of Effect of Multiple Doses of LOXO-305 on the Pharmacokinetics of Single Oral Doses of CYP1A2, CYP2C9, CYP2C19 Substrates in Healthy Participants

Healthy

United States
Eli Lilly and Company

Completed

A Study of Ixekizumab in Participants With Plaque Psoriasis

Psoriasis

United States
Bristol-Myers Squibb

Completed

Drug Interaction Study With a Potential Alzheimer's Disease Compound

Alzheimer Disease

United States
Indiana University
Hala Fadda; Butler University

Active, not recruiting

Assessment of Gastric pH Changes Induced by Ascorbic Acid Tablets

Hypochlorhydria

United States
AstraZeneca

Completed

Long-term Safety in Atrial Fibrillation Patients

Persistent or Permanent Nonvalvular Atrial Fibrillation
Boehringer Ingelheim

Completed

Study to Evaluate the Effect of Multiple Doses of BIRT 2584 XX Tablets on the Pharmacokinetic Parameters of Warfarin, Omeprazole, Caffeine, and Dextromethorphan in Healthy Male Volunteers

Healthy
Fundació Institut de Recerca de l'Hospital de la...

Completed

Compare VKA vs LMWH in Patients With Anticoagulation Criteria and Episode of Gastrointestinal Bleeding. (HEPACO)

Acute Gastrointestinal Bleeding

Spain
University of Cologne
Umm Al-Qura University

Completed

Effect of Acute Ethanol Consumption on The Activity of Major Cytochrome P450 Enzymes, NAT2 and P-glycoprotein

AOD Effects and Consequences

Germany
University of Padova

Completed

Optimal Duration of Anticoagulation in Deep Venous Thrombosis (MORGAGNI)

Deep Vein Thrombosis of Lower Limb | Lower Extremity Deep Venous Thrombosis Recurrent

Italy
Janssen Research & Development, LLC

Suspended

A Study to Evaluate the Effect of Ustekinumab on Cytochrome P450 Enzyme Activities Following Induction and Maintenance Dosing in Participants With Active Crohn's Disease or Ulcerative Colitis

Crohn Disease | Ulcerative Colitis

Germany, United States, United Kingdom, Belgium
R-Pharm International, LLC
IQVIA RDS Ireland Ltd; Thermo Fisher Scientific FS

Completed

Study in Subjects With Rheumatoid Arthritis to Evaluate the Effect of a Single Dose of Olokizumab on the Pharmacokinetics of Substrates for CYP1A2, CYP2C9, CYP2C19 and CYP3A4

Rheumatoid Arthritis

Bulgaria, Moldova, Republic of
Amgen

Recruiting

Study to Investigate the Effect of Rocatinlimab (AMG 451) on the Pharmacokinetics of Multiple Cytochrome P450 (CYP450) Substrates in Participants With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
Erasmus Medical Center; VU University of Amsterdam

Terminated

LV Thrombus After Acute AMI: A Randomized Controlled Trial

Ventricular Thrombosis Mural Following Myocardial Infarction

Netherlands
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Drug-drug Interaction Study Of Fluzoparib (SHR3162) on Patients With Recurrent Ovarian Cancer

Recurrent Ovarian Cancer

China
Boehringer Ingelheim

Completed

A Study in Healthy People to Test Whether BI 730357 Influences the Amount of Caffeine, Warfarin, Omeprazole, and Midazolam in the Blood

Healthy

Germany
Population Health Research Institute
Hamilton Health Sciences Corporation

Recruiting

Low INR to Minimize Bleeding With Mechanical Valves Trial (LIMIT)

Bleeding Post-mechanical Valve Replacement | Thromboembolism Post-mechanical Valve Replacement

Canada, Spain, Belgium, Russian Federation, Netherlands
Cedars-Sinai Medical Center

Recruiting

Assessment of TRanscathetEr and Surgical Aortic BiOprosthetic Valve Thrombosis and Its TrEatment With Anticoagulation (RESOLVE)

Prosthetic Valve Thrombosis

United States
Novartis Pharmaceuticals

Completed

A Phase I, Multi-center, Open Label, Drug-drug Interaction Study to Assess the Effect of Ceritinib on the Pharmacokinetics of Warfarin and Midazolam in Patients With ALK-positive Advanced Tumors

ALK-positive Advanced Tumors

Italy, Spain, Denmark, United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Anticoagulation For Pulmonary Hypertension in Sickle Cell Disease

Pulmonary Hypertension

United States
Research Institute for Complex Problems of Cardiovascular...

Unknown

Dabigatran in Patients With Atrial Fibrillation and Mitral Biological Prostheses

Atrial Fibrillation | Mitral Valve Stenosis and Insufficiency

Russian Federation
University Hospital Bispebjerg and Frederiksberg

Recruiting

Metabolism of Chlordiazepoxide in the Treatment of Alcohol Withdrawal Symptoms

Alcohol Withdrawal

Denmark
zr Pharma & GmbH

Completed

Pharmacokinetic Drug-Drug Interaction Study of Rucaparib (DDI)

Neoplasms

Poland
Boehringer Ingelheim

Completed

Effects of BI 201335 NA on Cytochrome P450 and P-glycoprotein Activity Using a Probe Drug Cocktail in Healthy Volunteers

Healthy
Espero Biopharma

Unknown

Tecarfarin Anti-Coagulation Trial (TACT) (TACT)

Thrombosis | Thromboembolism
Icahn School of Medicine at Mount Sinai

Completed

Genetic Response to Warfarin in Healthy Subjects

Healthy

United States
Boehringer Ingelheim

Completed

The Effect of BI 187004 on the Pharmacokinetics of Cytochrome P450 Substrates (Caffeine, Warfarin, Omeprazole, Metoprolol and Midazolam) and a P Glycoprotein Substrate (Digoxin)

Healthy

Germany
Kyushu University
Daiichi Sankyo Co., Ltd.

Completed

Clinical Trial to Investigate Safety and Efficacy of Edoxaban in Patients With CTEPH (KABUKI)

CTEPH

Japan
Bayer

Completed

BAY73-4506 Probe Substrate Study

Neoplasms

Canada
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of a Single Dose of CNTO 136 (Sirukumab) on CYP450 Enzyme Activities After Subcutaneous Administration in Patients With Rheumatoid Arthritis

Arthritis, Rheumatoid

Germany, Korea, Republic of, South Africa, Moldova, Republic of
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

Drug-drug Interaction Study With MDV3100 and a Cocktail of Substrates

Castration Resistant Prostate Cancer (CRPC) | Pharmacokinetics of MDV3100

South Africa
Novartis Pharmaceuticals

Completed

Evaluate the Effects of Patupilone on the Pharmacokinetics of Midazolam and Omeprazole in Patients With Advanced Malignancies

Solid Tumors

United States
Bayer
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

Switching Study From Warfarin to Rivaroxaban

Venous Thrombosis

Germany
Jung-min Ahn

Recruiting

Long-term Anticoagulation With Oral Factor Xa Inhibitor Versus Vitamin K Antagonist After Mechanical Aortic Valve Replacement (RENOVATE)

Thromboembolism | AORTIC VALVE DISEASES

Korea, Republic of
GlaxoSmithKline

Completed

A Placebo-controlled Study to Investigate the Safety, and Pharmacokinetics of Oral GSK626616AC in Healthy Subjects

Healthy Subjects | Anaemia

Australia
Sanofi

Completed

SR34006 Compared to Vitamin K Antagonist (VKA) in the Treatment of Pulmonary Embolism

Pulmonary Embolism

United Kingdom, United States, Canada, Argentina, Austria, Norway, Czech Republic, Denmark, France, Australia, Belgium, Brazil, Finland, Germany, Italy, Netherlands, Poland, Spain, Sweden, Switzerland
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Arterial Disease Multifactorial Intervention Trial (ADMIT)

Heart Diseases | Cardiovascular Diseases | Vascular Diseases | Arterial Occlusive Diseases | Diabetes Mellitus
Boehringer Ingelheim

Withdrawn

Effect of BI 1181181 on Midazolam, Warfarin, Omeprazole and Digoxin

Healthy

Germany

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