Search clinical trials for: Muscarinic Antagonists

Total 32871 results

Center for Clinical Pharmacology Research Bdbeq...
Laboratorio Elea Phoenix S.A.

Unknown

Single Dose Bioequivalence Study of Darifenacin Tablets 7.5 mg in Fed Healthy Volunteers.

Bioequivalency

Uruguay
Hywel Dda Health Board
Swansea University

Completed

sTep dOWn Inhalers in the reAl woRlD (TOWARD)

Chronic Obstructive Pulmonary Disease

United Kingdom
Boehringer Ingelheim

Completed

Effectiveness of Triple Therapy in COPD

Pulmonary Disease, Chronic Obstructive

United Kingdom
Sanofi
Regeneron Pharmaceuticals

Completed

Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate-to-severe COPD With Type 2 Inflammation (BOREAS)

Chronic Obstructive Pulmonary Disease

Spain, Argentina, China, Mexico, Canada, Ukraine, Israel, Italy, Czechia, Korea, Republic of, Bulgaria, Chile, Denmark, Finland, Germany, Hungary, Japan, Poland, Romania, Russian Federation, Slovakia, Sweden, Turkey, United States
Chronic Obstructive Pulmonary Disease Trial Network...

Recruiting

Once Daily Long-Acting Muscarinic Antagonists Administered in the Evening for Prevention of Chronic Obstructive Pulmonary Disease Exacerbations Requiring Hospitalization or Death From Any Cause

COPD Exacerbation

Denmark
Sanofi
Regeneron Pharmaceuticals

Active, not recruiting

Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate to Severe COPD With Type 2 Inflammation (NOTUS)

Chronic Obstructive Pulmonary Disease

Greece, Belgium, Spain, Argentina, Hungary, South Africa, United Kingdom, France, Latvia, Germany, Netherlands, Russian Federation, Ukraine, United States, Australia, Brazil, Bulgaria, Canada, Chile, Colombia, Czechia, Lithuania, Me... and more
Boehringer Ingelheim

Completed

A Study in South Korea Using Medical Records to Look at Different Treatments for Chronic Obstructive Airway Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Korea, Republic of
Boehringer Ingelheim
HealthCore-NERI

Completed

Assessment In a Real World Setting of the Effect of Inhaled Steroid-based Triple Therapy Versus the Combination of Tiotropium and Olodaterol on Reducing Chronic Obstructive Pulmonary Disease (COPD) Exacerbations [AIRWISE]

Pulmonary Disease, Chronic Obstructive

United States
Dong-A ST Co., Ltd.

Recruiting

A Study to Evaluate the Effects of Renal Function on Pharmacokinetics and Safety of DA-8010

Healthy | Renal Impairment

Korea, Republic of
Swiss Paraplegic Centre Nottwil

Completed

Effects of Antimuscarinics on Cognition in Spinal Cord Injury

Mild Cognitive Impairment | Spinal Cord Injuries

Switzerland
Pfizer

Completed

Study Of Fesoterodine In Pediatric Overactive Bladder Patients Aged 8-17 Years

Overactive Bladder | Neurogenic Detrusor Overactivity

United States
Pfizer

Completed

UK Study Assessing Flexible Dose Fesoterodine in Adults (SAFINA)

Urinary Bladder, Overactive

United Kingdom
Pfizer

Completed

Phase1, Single Dose, Crossover Study to Determine Bioequivalence

Healthy

Singapore
Pfizer

Completed

Phase 1, Single Dose, Crossover Study to Determine Bioequivalence and to Investigate Food Effect

Food | Therapeutic Equivalency

Japan
Guang'anmen Hospital of China Academy of Chinese...

Completed

Effect of Electroacupuncture Versus PFMT Plus Solifenacin for Mixed Urinary Incontinence

Urinary Incontinence

China
TheraVida, Inc.

Completed

Effects of Novel Combinations of Tolterodine/Pilocarpine on Pharmacokinetics (PK) and Pharmacodynamics (PD) of Tolterodine in Healthy Subjects

Incontinence
University of Pennsylvania
Pfizer

Completed

Fall Prevention in Older Adults With OAB

Overactive Bladder
Dong-A ST Co., Ltd.

Unknown

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of DA-8010 in Healthy Subjects

Overactive Bladder
Karuna Therapeutics

Completed

Pilot Study Comparing Effects of Xanomeline Alone to Xanomeline Plus Trospium

Schizophrenia

United States
Pfizer

Completed

Post Marketing Surveillance Of Fesoterodine In Filipino Patients With Over Active Bladder

Over Active Bladder

Philippines
LG Life Sciences
Kyorin Pharmaceutical Co.,Ltd

Completed

Comparison of Efficacy and Safety Between Imidafenacin and Fesoterodine in Patients With Overactive Bladder

Overactive Bladder

Korea, Republic of
Pfizer

Completed

Evaluation Of The Ability Of Fesoterodine To Increase Urethral Pressure In Stress Urinary Incontinence Patients

Stress Urinary Incontinence

Denmark
Pfizer

Completed

Fesoterodine Flexible Dose Study

Overactive Bladder

United States
Novartis

Completed

A Long-Term Safety, Tolerability and Efficacy Study of Darifenacin in Adult Patients With Overactive Bladder

Overactive Bladder Syndrome

United States
University of British Columbia
Pfizer; Vancouver Coastal Health; International Collaboration on Repair Discoveries

Completed

Fesoterodine for Amelioration of Autonomic Dysreflexia (AD) Following Spinal Cord Injury (SCI)

Autonomic Dysreflexia

Canada
Stéphane Bolduc
Pfizer

Completed

Extension Study of Fesoterodine for Overactive Bladder Syndrome in Children. (FOXY2015)

Overactive Bladder

Canada
Pfizer

Completed

Local, Open-Label, Extension Trial Of The Efficacy And Safety Of Fesoterodine In Elderly Patients With Overactive Bladder

Urinary Bladder, Overactive

Portugal
Pfizer

Completed

A Study Of Efficacy And Safety Of Fesoterodine In Vulnerable Elderly Subjects With Overactive Bladder

Overactive Bladder

United States
Pfizer

Completed

Drug Use Investigation for Toviaz

Overactive Bladder (OAB)
Pfizer

Completed

Study In Patients With Overactive Bladder Treated With Toviaz® After Failure Of Previous Therapy

Overactive Bladder | Urinary Incontinence

Slovakia
Novartis
Procter and Gamble

Completed

Study to Compare How the Body Changes the Blood Level of Darifenacin Tablet Form vs. the Modified Release Liquid Form in Healthy Subjects

Healthy

India
Pfizer

Completed

A Clinical Trial To Assess Fesoterodine On Treatment Satisfaction And Symptom Improvement In Overactive Bladder Patients

Overactive Bladder

Costa Rica, United States, Korea, Republic of, Germany, Slovakia, Ukraine, Belgium, Poland, Czechia
Pfizer

Completed

This Is An Open-Label Study To Evaluate Fesoterodine Plus "Your Way" Patient Support Plan In Patients With Symptoms Of Overactive Bladder

Overactive Bladder
Pfizer

Completed

Toviaz Post Marketing Surveillance Study

Overactive Bladder

Korea, Republic of
Mayo Clinic
Pfizer

Completed

Effects of Tolterodine, a Non-Specific Muscarinic Antagonist, on Gastrointestinal Transit in Healthy Subjects

Health

United States
Rambam Health Care Campus
Pfizer

Unknown

Assessing the OAB-8 Questionnaire as a Tool to Measure Treatment Outcome

Overactive Bladder

Israel
Karuna Therapeutics

Terminated

An Open-label Study to Assess the Long-term Safety, Tolerability, Effectiveness, and Durability of Effect of KarXT in Patients With DSM-5 Diagnosis of Schizophrenia (PENNANT)

Schizophrenia

United States
Pfizer

Completed

A Study To Estimate The Effects Of Food On Drug Fesoterodine Fumarate And The Pharmacokinetics Of 5-Hydroxymethyl Tolterodine (5-HMT) In Healthy Volunteers

Urinary Bladder, Overactive

Singapore
Washington University School of Medicine

Completed

Comparative Urine Proteomic Studies of Overactive Bladder in Humans

Overactive Bladder

United States
National Taiwan University Hospital

Unknown

Post-treatment Novmalized Urodynamiz Findings as the Golden Standard of Objective Cure for Female Overactive Bladder Patients Receiving Antimuscarinic Drug

Overactive Bladder Syndrome

Taiwan
University of California, San Francisco
Pfizer

Completed

Bringing Simple Urge Incontinence Diagnosis & Treatment to Providers (BRIDGES) (BRIDGES)

Overactive Bladder | Urge Urinary Incontinence

United States
Pfizer

Completed

Fesoterodine "add-on" Male Overactive Bladder Study

Overactive Bladder Syndrome

United States, Canada, Greece, Brazil, Korea, Republic of, Singapore, Poland, India, Norway, Slovakia, Spain, Belgium, Philippines, Netherlands, Sweden, Thailand, Malaysia, Germany, Colombia
Pfizer

Completed

Long Term Study To Evaluate the Safety, Tolerability and Efficacy of Fesoterodine for Overactive Bladder.

Overactive Bladder

Japan
Novartis

Completed

A 12-Week Study to Evaluate the Efficacy of Darifenacin to Increase the Warning Time in Patients With Overactive Bladder.

Overactive Bladder Syndrome

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Detrol LA In Men With Overactive Bladder.

Overactive Bladder (OAB)

United States, Canada, Germany, Korea, Republic of, Spain, Turkey, Taiwan, Italy, Slovakia, Denmark, South Africa, United Kingdom, Mexico, Sweden, Norway
Far Eastern Memorial Hospital
National Science Council, Taiwan

Completed

Bladder Wall Blood Perfusion Pattern and Sexual Dysfunction in Female Patients With Lower Urinary Tract Symptoms, and the Association of That Perfusion Pattern and Therapeutic Efficacy of Antimuscarincs for Female Overactive Bladder Syndrome.

Lower Urinary Tract Symptoms

Taiwan
University of Missouri-Columbia

Terminated

Preoperative Use of Darifenacin (Enablex) to Alleviate Postoperative Ureteral Stent Pain

Overactive Bladder | Renal Colic | Pain, Postoperative

United States
KYU-SUNG LEE
Astellas Pharma Korea, Inc.

Completed

A Study to Evaluate Add on Effect of Solifenacin in Men With Overactive Bladder Symptoms After Tamsulosin Monotherapy for 4 Weeks

Overactive Bladder

Korea, Republic of
Loyola University
Astellas Pharma US, Inc.

Completed

Bacterial Genomic Sequencing in Overactive Bladder

Overactive Bladder

United States
Astellas Pharma Inc
Astellas Pharma Korea, Inc.

Completed

A Study to Evaluate Response of Over Active Bladder Symptom Score to Solifenacin Treatment (RESORT-2)

Over Active Bladder

Korea, Republic of

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