Search clinical trials for: NK1 Antagonist

Total 33126 results

St. Joseph's Healthcare Hamilton
University Health Network, Toronto

Unknown

Neurokinin (NK) 1 Antagonist for Pathological Aggression for Harmful, Impulsive, and Self-/Aggressive Behaviour (AHIMSA-1)

Aggression

Canada
Aibin Liang，MD，Ph.D.

Recruiting

Study of Cord Blood-derived CAR NK Cells Targeting CD19/CD70 in Refractory/Relapsed B-cell Non-Hodgkin Lymphoma

Refractory or Relapsed B-cell Non-Hodgkin Lymphoma

China
Bone Biologics Corp

Recruiting

Evaluation of NB1 Bone Graft Following Lumbar Interbody Arthrodesis

Degenerative Disc Disease | Spondylolisthesis

Australia
National Institute of Allergy and Infectious Diseases...

Recruiting

Evaluating the Infectivity, Safety and Immunogenicity of Respiratory Syncytial Virus Vaccines, RSV 6120/∆NS1 and RSV 6120/F1/G2/∆NS1, in RSV-Seropositive Children and RSV-Seronegative Infants and Children

RSV Infection

United States
Chinese PLA General Hospital
Tsinghua University

Unknown

Autologous Natural Killer T Cells Infusion for the Treatment of Cancer

Glioma | Breast Cancer | Pancreatic Cancer | Prostate Cancer | Colon Cancer | Hepatocellular Cancer | Squamous Cell Lung Cancer

China
Peking University Cancer Hospital & Institute

Unknown

A Clinical Trial of Adoptive Transfer With Autologous NKT Cells in Metastatic Melanoma Patients

Melanoma

China
Massachusetts General Hospital
Patient-Centered Outcomes Research Institute

Not yet recruiting

A Decentralized Clinical Trial to Promote Evidence-Based Care for Underserved Patients With Neurofibromatosis 1

Neurofibromatosis 1

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

Clinical Study of Cord Blood-derived CAR NK Cells Targeting CD19/CD70 in Refractory/Relapsed B-cell Non-Hodgkin Lymphoma

B-cell Non Hodgkin Lymphoma

China
Niiki Pharma Inc.

Completed

Dose Escalation Study of NKP-1339 to Treat Advanced Solid Tumors

Solid Tumors

United States
Duzce University
Cukurova University

Completed

Needle Knife Fistulotomy Versus Partial Ampullary Endoscopic Mucosal Resection for Difficult Biliary Cannulation

Common Bile Duct Calculi | Biliary Disease | Biliary Stricture | Malignant Hepatobiliary Neoplasm | Pancreatic Disease

Turkey
Prof. Dr. Fridoon Jawad Ahmad
University of Lahore; Bahria International Hospital

Unknown

To Determine the Efficacy of Neurokinin 1 Receptor Antagonist as a Therapeutic Tool Against Cytokine Storm and Respiratory Failure in Covid-19 Patients

Neurokinin 1 Receptor, Substance P, Respiratory Illness, Inflammation, Covid-19, Coronavirus

Pakistan
Baylor College of Medicine
National Institute of Mental Health (NIMH)

Completed

Substance P Antagonist in the Treatment of Posttraumatic Stress Disorder

PTSD

United States
Radboud University Medical Center
UMC Utrecht; Erasmus Medical Center; The Netherlands Cancer Institute; Leiden University...

Recruiting

NKI Therapy Compared to Usual Care of Recurrent Esophagogastric Anastomotic Strictures (SAMURAI)

Esophageal Stricture | Anastomotic Stenosis | Dilation of Esophagus Due to Disease

Netherlands
GL Pharm Tech Corporation

Completed

A PK Study GL2702 GLARS-NF1 and Omix Ocas® in Healthy Male Volunteers

Healthy

Korea, Republic of
Celyad Oncology SA

Unknown

A Dose Escalation Phase I Study to Assess the Safety and Clinical Activity of Multiple Cancer Indications (THINK)

Acute Myeloid Leukemia/Myelodysplastic Syndrome | Multiple Myeloma (MM)

United States, Belgium
University of Oklahoma
University of Michigan; Emory University

Recruiting

REVEAL Biomarkers of Engraftment After Alternative Donor HSCT (REVEAL)

Primary Graft Failure

United States
Henry M. Jackson Foundation for the Advancement...
The Citadel, The Military College of North Carolina

Unknown

Test and Evaluation of Non-Invasive Neuro-Assessment Devices (NINAD: Neurokinetics, Inc, iPAS (NINADiPAS)

Traumatic Brain Injury | Post Traumatic Stress Disorder

United States
vTv Therapeutics

Completed

A 6 Week Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of GK1-399 in Type 2 Diabetes

Type 2 Diabetes Mellitus

United States
Cairo University

Not yet recruiting

Effect of Commiphora Myrrh Solution as a Root Canal Irrigant on Post Operative Pain and Bacterial Load Reduction in Necrotic Tooth

Necrotic Pulp
Bio-Rad Laboratories
Centers for Disease Control and Prevention; American National Red Cross

Completed

Dengue Virus NS1 Antigen (Bio-Rad) Clinical Protocol

Mass Screening

United States, Puerto Rico
GL Pharm Tech Corporation

Completed

Study to Investigate the Efficacy and Safety of GL2702 GLARS-NF1tablet and Harnal-D - Tablet in BPH Patients With LUTS (GL2702)

Benign Prostatic Hyperplasia

Korea, Republic of
Chongqing Public Health Medical Center
Zhejiang Qixin Biotech; Chongqing Sidemu Biotech

Unknown

A Phase I/II Study of Universal Off-the-shelf NKG2D-ACE2 CAR-NK Cells for Therapy of COVID-19

COVID-19

China
Tracon Pharmaceuticals Inc.
Janssen Pharmaceutica N.V., Belgium

Completed

Phase 1/2A Study of TRC253, an Androgen Receptor Antagonist, in Metastatic Castration-resistant Prostate Cancer Patients

Metastatic Castrate-resistant Prostate Cancer | Adenocarcinoma, Prostate

United States
ImmunityBio, Inc.

Unknown

QUILT-3.009: Patients With Stage III (IIIB) or Stage (IV) Merkel Cell Carcinoma (MCC)

Stage IIIB Merkel Cell Carcinoma | Stage IV Merkel Cell Carcinoma

United States
University of Michigan Rogel Cancer Center

Active, not recruiting

Olanzapine for the Prevention of Chemotherapy Induced Nausea and Vomiting in Gynecologic Oncology Patients

Gynecologic Cancer

United States
Bristol-Myers Squibb

Completed

A Phase I Dose-Escalation Study of BMS-641988 in Patients With Castration-Resistant Prostate Cancer

Prostate Cancer

United States
AV7 Limited

Completed

K1-70 - A Study in Subjects With Graves' Disease

Graves' Disease

United Kingdom
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Unknown

INFUSION OF ALLOREACTIVE NATURAL KILLER (NK) CELLS AS CONSOLIDATION STRATEGY FOR ACUTE MYELOID LEUKEMIA PATIENTS (NKAML)

Adult Acute Myeloid Leukemia in Remission

Italy
Asclepius Technology Company Group (Suzhou) Co....

Unknown

Clinical Research of ROBO1 Specific BiCAR-NK Cells on Patients With Pancreatic Cancer

Pancreatic Cancer

China
Hangzhou Cheetah Cell Therapeutics Co., Ltd

Terminated

NKG2D CAR-NK Cell Therapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia

Safety and Efficacy

China
National Heart, Lung, and Blood Institute (NHLBI)
Zymedi, Co., Ltd.

Recruiting

Study of Intravenous ZMA001 in Healthy Subjects

Pulmonary Arterial Hypertension PAH

United States
Asclepius Technology Company Group (Suzhou) Co....

Unknown

Clinical Research of ROBO1 Specific BiCAR-NK/T Cells on Patients With Malignant Tumor

Malignant Tumor

China
ATGen Canada Inc
Maisonneuve-Rosemont Hospital

Completed

Measurement of NK Cell Activity in Whole Blood in Subjects Being Screened for Colorectal Cancer Using Colonoscopy

Natural Killer Cell Cytokine Production

Canada
Hrain Biotechnology Co., Ltd.
Shanghai Changzheng Hospital

Recruiting

To Evaluate the Safety and Efficacy of Human BCMA Targeted CAR-NK Cells Injection for Subjects With R/R MM or PCL

Multiple Myeloma | Plasma Cell Leukemia

China
ATGen Canada Inc

Terminated

Analysis of Natural Killer Cell Activity (NKA) in Whole Blood in High Risk Subjects Undergoing Colonoscopy (ANKA-HR)

Colorectal Cancer | Immunity, Innate

Canada
Center for Clinical Pharmacology Research Bdbeq...
Laboratorio Elea Phoenix S.A.

Unknown

Single Dose Bioequivalence Study of Darifenacin Tablets 7.5 mg in Fed Healthy Volunteers.

Bioequivalency

Uruguay
Celyad Oncology SA

Terminated

Hepatic Transarterial Administrations of NKR-2 in Patients With Unresectable Liver Metastases From Colorectal Cancer (LINK)

Colon Cancer Liver Metastasis

Belgium
Celyad Oncology SA

Unknown

Dose Escalation and Dose Expansion Phase I Study to Assess the Safety and Clinical Activity of Multiple Doses of NKR-2 Administered Concurrently With FOLFOX in Colorectal Cancer With Potentially Resectable Liver Metastases (SHRINK)

Colon Cancer Liver Metastasis

Belgium
Suzhou Kintor Pharmaceutical Inc,

Completed

The Safety and Tolerability of GT0918 in Subjects With mHSPC and mCRPC

Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) | Metastatic Castrate Resistant Prostate Cancer (mCRPC)

United States
Nationwide Children's Hospital

Not yet recruiting

Intra-tumoral Injection of Natural Killer Cells in High-Grade Gliomas (NK HGG)

High Grade Glioma

United States
BioCardia, Inc.

Not yet recruiting

AllogeneiC Expanded Human MSC Therapy in Patients Recovering From COVID-19 Acute Respiratory Distress Trial (ACE_CARD)

ARDS, Human
Xinxiang medical university
First Affiliated Hospital of Xinjiang Medical University

Completed

NK Cells Treatment for COVID-19

Novel Coronavirus Pneumonia

China
jiuwei cui

Unknown

NK Cell-based Immunotherapy as Maintenance Therapy for Small-Cell Lung Cancer.

Small Cell Lung Cancer

China
Instituto de Investigación Hospital Universitario...

Recruiting

"Phase I / II Study on Infusion of Natural Killer Cells After Haploidentical Transplantation in Pediatric Patients" (PHINK)

High-risk Leukemias

Spain
Suzhou Kintor Pharmaceutical Inc,

Completed

Safety, Tolerability, and PK of GT0918 (Proxalutamide) in Subjects With Metastatic Castrate Prostate Cancer

Metastatic Castrate Resistant Prostate Cancer (mCRPC)

United States
King Abdullah International Medical Research Center

Recruiting

The Efficacy of Leukotriene Inhibitor in Adult Patients With Moderate SARS-COV-2 Symptoms (COVID19) (PROMISE)

Moderate Covid19

Saudi Arabia
Fondazione Policlinico Universitario Agostino Gemelli...
Ministry of Health, Italy

Terminated

Haploidentical Stem Cell Transplant With or Without NK Cell Infusion in AML and MDS (Bigeminy)

Acute Myeloid Leukemia | Myelodysplasia

Italy
Xiangyang No.1 People's Hospital
Qingdao Haier Biotechnology Co.,Ltd.

Not yet recruiting

Safety and Efficacy of Autologous NK Cell Adjuvant Therapy for Relapsed/Refractory Non-Hodgkin's B-cell Lymphoma

B-cell Lymphoma Refractory | B-cell Lymphoma Recurrent | NK Cell

China
Shantou University Medical College
Guangdong ProCapZoom Biosciences Co., Ltd.

Not yet recruiting

Single-arm, Open-label Clinical Study of SZ011 in the Treatment of Ovarian Epithelial Carcinoma

Ovarian Epithelial Carcinoma
Hangzhou Cheetah Cell Therapeutics Co., Ltd

Recruiting

NKG2D CAR-NK & Ovarian Cancer

Ovarian Cancer

China

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