Search clinical trials for: Natural History Study

Total 8185 results

University of Florida
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Adequacy of the New Pediatric Isoniazid/Rifampin/Pyrazinamide (HRZ) Tablet

Tuberculosis | Human Immunodeficiency Virus | Coinfection

Ghana
Imperial College London

Completed

TNF-alpha Directed Therapy in Asthma

Asthma

United Kingdom
University of Kansas Medical Center

Completed

Multimodal Pain Study in Free Flap Patients

Head and Neck Cancer | Analgesia

United States
Washington State University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters

Interaction | Endogenous Biomarkers

United States
Memorial Sloan Kettering Cancer Center
National Institutes of Health (NIH)

Completed

Outcomes From Home in Patients Recovering From Major Gynecologic Cancer Surgery: Measuring Symptoms and Health-related Quality of Life

Ovarian Cancer | Fallopian Tube Cancer | Vulvar Cancer | Vaginal Cancer | Peritoneal Cancer | Uterine Cancer

United States
Washington University School of Medicine
National Cancer Institute (NCI)

Completed

FOLFIRINOX Plus PF-04136309 in Patients With Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma

Pancreatic Neoplasms

United States
Taipei Veterans General Hospital, Taiwan

Completed

Efficacy of Combined Ultrasound Guided Steroid Injection and Splinting in Patients With Carpal Tunnel Syndrome

Carpal Tunnel Syndrome
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Advanced Cancer That is Metastatic or Cannot Be Removed By Surgery

Unspecified Adult Solid Tumor, Protocol Specific

United States
Alcon Research

Completed

A Clinical Safety and Efficacy Comparison of NEVANAC 0.1% to Vehicle After Cataract Surgery in Diabetic Retinopathy Patients

Macular Edema
Yunnan AIDS Care Center

Unknown

Safety and Efficacy of Raltegravir+TDF+3TC in HBV/HIV Co-infected Patients

HIV Infections | HBV Coinfection

China
Margaux M. Salas, PhD

Not yet recruiting

The Effect of Outpatient Ketamine Infusion on Chronic Neuropathic Pain and PTSD

PTSD | Neuropathic Pain
Germans Trias i Pujol Hospital

Not yet recruiting

Precision Psychiatry for Depression: Immune Response and Affective Symptoms as Predictors of Response to Antidepressants (LYMPHODEP)

Depression | Inflammation | Immunity | Antidepressants

Spain
Cambridge University Hospitals NHS Foundation Trust
Obstetric Anaesthetists' Association

Recruiting

Peripheral Skin Temperature Changes Following Spinal Anaesthesia for Category 4 LSCS

Anesthesia

United Kingdom
Yi Luo

Recruiting

A Single-arm Trial of Prophylactic Tocilizumab for Acute GVHD Prevention After Haploidentical HSCT.

Leukemia | Graft-versus-host-disease

China
First Affiliated Hospital of Zhejiang University

Recruiting

A Study Comparing Haploidentical Hematopoietic Stem Cell Transplantations (HSCTs) From Young Non-first-degree and Older First-degree Donors in Hematological Malignancies

Leukemia

China
Masonic Cancer Center, University of Minnesota

Active, not recruiting

Hematopoietic Stem Cell Transplantation in the Treatment of Infant Leukemia

Myelodysplastic Syndromes | Leukemia | Previously Treated Myelodysplastic Syndrome | Secondary Acute Myeloid Leukemia | Childhood Acute Myeloid Leukemia in Remission | Childhood Acute Lymphoblastic Leukemia in Remission | Recurrent Childhood Acute Myeloid Leukemia | Secondary Myelodysplastic Syndrome and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Antiandrogen Therapy With or Without Axitinib Before Surgery in Treating Patients With Previously Untreated Prostate Cancer With Known or Suspected Lymph Node Metastasis

Metastatic Malignant Neoplasm in Lymph Node | Prostate Ductal Adenocarcinoma | Stage III Prostate Adenocarcinoma AJCC v7 | Stage IV Prostate Adenocarcinoma AJCC v7

United States
Northwestern University
National Cancer Institute (NCI); Novartis

Completed

BYL719 + T-DM1 in HER2(+) Metastatic Breast Cancer Pts Who Progress on Prior Trastuzumab & Taxane Tx

HER2-positive Breast Cancer | Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer | Recurrent Breast Cancer

United States
Mohammed M Milhem
Genentech, Inc.

Completed

Bevacizumab, Chemotherapy and Valproic Acid in Advanced Sarcomas

Sarcoma | Soft Tissue Sarcoma | Metastatic Sarcoma | Locally Advanced Sarcoma | Unresectable Sarcoma

United States
Mayo Clinic
National Cancer Institute (NCI)

Terminated

Breath Test for Women Receiving Tamoxifen in the Prevention or Treatment of Breast Cancer

Breast Cancer

United States
National Cancer Institute (NCI)

Completed

Cholecalciferol and Genistein Before Surgery in Treating Patients With Early Stage Prostate Cancer

Prostate Adenocarcinoma | Stage I Prostate Cancer | Stage IIA Prostate Cancer | Stage IIB Prostate Cancer

United States
National Cancer Institute (NCI)

Completed

Carboplatin and Paclitaxel With or Without Sorafenib Tosylate in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

Stage IV Skin Melanoma | Recurrent Melanoma | Stage IIIB Skin Melanoma | Stage IIIC Skin Melanoma | Mucosal Melanoma | Stage IIIA Skin Melanoma

United States, Australia
Intech Biopharm Ltd.

Completed

Efficacy Study of SYN006 HFA MDI in Asthma Patients

Asthma

Taiwan
Frank Lippert
The Borrow Foundation

Completed

An in Situ Study on the Impact of Fluoride Dose and Concentration in Milk on Its Anti-caries Efficacy

Caries

United States
University of Nebraska
National Cancer Institute (NCI)

Recruiting

FOLFIRINOX With Digoxin in Patients With Resectable Pancreatic Cancer

Pancreas Cancer | Adenocarcinoma of the Pancreas

United States
Eli Lilly and Company

Active, not recruiting

A Study of LY2835219 (Abemaciclib) in Combination With Therapies for Breast Cancer That Has Spread

Breast Neoplasms

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

Therapeutic Autologous Lymphocytes, Aldesleukin, and Denileukin Diftitox in Treating Patients With Stage III-IV Melanoma

Recurrent Melanoma | Stage IV Melanoma | Stage III Melanoma

United States
German High-Grade Non-Hodgkin's Lymphoma Study...

Completed

Rituximab and Combination Chemotherapy in Treating Older Patients With Previously Untreated B-Cell Lymphoma

Lymphoma

Switzerland, Germany, Italy, Netherlands, Poland, Sweden, United Kingdom, France, Czechia
Acrotech Biopharma Inc.

Completed

Study of Pralatrexate & Gemcitabine With B12 & Folic Acid to Treat Relapsed/Refractory Lymphoproliferative Malignancies

B-cell Lymphoma | Hodgkin's Lymphoma | Relapsed or Refractory Lymphoproliferative Malignancies | Peripheral T-cell Lymphoma | Waldenstrom's Macroglobulinemia

United States
Merck Sharp & Dohme LLC

Terminated

Evaluation of Renal Function, Efficacy, and Safety When Switching From Tenofovir/Emtricitabine Plus a Protease Inhibitor/Ritonavir, to a Combination of Raltegravir (MK-0518) Plus Nevirapine Plus Lamivudine in HIV-1 Participants With Suppressed Viremia and Impaired Renal Function (MK-0518-284) (RANIA)

HIV Infections
City of Hope Medical Center

Completed

Hepatic Arterial Infusion of Floxuridine, Gemcitabine Hydrochloride, and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer Previously Treated With Surgery

Liver Metastases | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States
Eli Lilly and Company

Completed

A Study of LY2216684 in Healthy Participants Receiving Albuterol or Propanolol

Major Depressive Disorder

United States
National Cancer Institute (NCI)

Completed

Veliparib and Pegylated Liposomal Doxorubicin Hydrochloride in Treating Patients With Recurrent Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer or Metastatic Breast Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Breast Carcinoma | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast Carcinoma | Male Breast Carcinoma | Stage IV Breast Cancer AJCC...

United States
Novartis Pharmaceuticals

Completed

Combined Antiinflammatory and Angiostatic Therapy in Patients With Hormone-refractory Prostate Cancer (INV342)

Prostate Cancer

Germany
Clinical Research Management, Inc.
Duke University; Bill and Melinda Gates Foundation; Syneos Health; University of... and other collaborators

Unknown

Multiple Treatments for Ebola Virus Disease (EVD)

Ebola Virus Disease
St Stephens Aids Trust

Completed

Atripla to Raltegravir Switch Study for CNS Toxicity (SSAT036)

HIV Infection

United Kingdom
French National Agency for Research on AIDS and...
Gilead Sciences; Abbott

Completed

Evaluation of a Lopinavir/Ritonavir Monotherapy vs a Triple Therapy as Maintenance Regimens in HIV-1 Infected Patients (ANRS 140 DREAM)

HIV Infections

France
National Cancer Institute (NCI)

Terminated

Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane Hydrochloride in Treating Young Patients With Relapsed or Refractory Solid Tumors, Lymphoma, or Leukemia

Unspecified Childhood Solid Tumor, Protocol Specific | Peripheral T-cell Lymphoma | Angioimmunoblastic T-cell Lymphoma | Childhood Chronic Myelogenous Leukemia | Cutaneous B-cell Non-Hodgkin Lymphoma | Hepatosplenic T-cell Lymphoma | Intraocular Lymphoma | Recurrent Childhood Acute Lymphoblastic... and other conditions

United States, Canada
Bristol-Myers Squibb

Completed

Study Comparing the Safety and Efficacy of Belatacept With That of Cyclosporine in Patients With a Transplanted Kidney

Kidney Transplantation | Graft Rejection | Renal Transplantation

United States
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Young Patients With Advanced Solid Tumors

Unspecified Childhood Solid Tumor, Protocol Specific | Recurrent Childhood Brain Stem Glioma | Childhood Central Nervous System Germ Cell Tumor | Childhood Central Nervous System Choriocarcinoma | Childhood Central Nervous System Germinoma | Childhood Central Nervous System Mixed Germ Cell... and other conditions

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Ketoconazole, Dexamethasone, and Hydrocortisone in Treating Patients With Prostate Cancer That Did Not Respond to Androgen-Deprivation Therapy

Prostate Cancer
M.D. Anderson Cancer Center

Completed

Valproic Acid-Based 2-Agent Oral Regimens for Patients With Advanced Solid Tumor

Solid Tumors

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Gossypol (AT-101) and Temozolomide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Gleneagles Hospital
Samsung Medical Center; Asan Medical Center; Chonnam National University Hospital and other collaborators

Completed

Higher Frequency Zoledronic Acid in the Treatment of Multiple Myeloma (dtZ)

Multiple Myeloma

Korea, Republic of, Singapore, India
Osijek University Hospital
Josip Juraj Strossmayer University of Osijek

Recruiting

Propofol and Dexmedetomidin vs Midazolam Intraoperative Sedation and POCD (ProDex-POCD)

Postoperative Cognitive Dysfunction | Postoperative Pain, Acute | Pertrochanteric Fracture

Croatia
Memorial Sloan Kettering Cancer Center

Completed

Serum Estradiol Levels In Postmenopausal Women With Breast Cancer Receiving Adjuvant Aromatase Inhibitors and Vaginal Estrogen

Breast Cancer | Atrophic Vaginitis

United States
Newron Pharmaceuticals SPA

Completed

MOTION, Safinamide in Early IPD, as add-on to Dopamine Agonist (MOTION)

Idiopathic Parkinson's Disease

United States, Spain, Brazil, Peru, Colombia, Germany, Argentina, India, Croatia, Czech Republic, Italy, South Africa, Finland, Portugal, Canada, Slovakia, Bulgaria, Chile, Mexico, Poland
University of Colorado, Denver
Children's Hospital Los Angeles

Recruiting

Therapies for Down Syndrome Regression Disorder

Down Syndrome | Regression

United States
Menoufia University

Not yet recruiting

Different Induction Protocols in PCOS After Clomiphene Citrate Failed Pregnancy in Non-IVF Cycles

Infertility, Female
Postgraduate Institute of Dental Sciences Rohtak

Recruiting

Comparision Efficacy of Carbamazepine & Oxcarbazepine in the Treatment of Trigeminal Neuralgia- a Randomised Clinical Trial

Trigeminal Neuralgia

India

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