Search clinical trials for: ONO-8577

Total 12306 results

Merck Sharp & Dohme LLC

Recruiting

Safety and Pharmacokinetic Study of Oral MK-8527 QM in Participants at Low-Risk for HIV-1 Infection (MK-8527-007)

HIV | HIV Pre-exposure Prophylaxis

United States, South Africa, Israel
Jin Chen-jin

Completed

Treatment Trial for Acute Central Serous Chorioretinopathy

Acute Central Serous Chorioretinopathy

China
Merck Sharp & Dohme LLC

Not yet recruiting

Ulonivirine (MK-8507) in Participants With Mild or Moderate Hepatic Impairment (MK-8507-014)

Hepatic Insufficiency
Merck Sharp & Dohme LLC

Completed

Trial to Determine the Maximum Tolerated Dose (MTD) Based on Safety and Tolerability, of Org 26576 in Participants With Major Depressive Disorder (174001/P05704/MK-8777-001)

Depression
Merck Sharp & Dohme LLC

Completed

Dose Finding Study in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)(174007/P05805/MK-8777-003)

Attention Deficit Hyperactivity Disorder
Kowa Research Institute, Inc.

Completed

Study to Investigate the Efficacy and Pharmacokinetic Profile of K-877-ER Compared to K-877-IR

Dyslipidemia

United States
Merck Sharp & Dohme LLC

Not yet recruiting

A Study of MK-8527 in Participants With Moderate and Severe Renal Impairment (MK-8527-008)

Renal Impairment
Salarius Pharmaceuticals, LLC

Completed

Phase 1 Trial of the LSD1 Inhibitor SP-2577 (Seclidemstat) in Patients With Advanced Solid Tumors

Advanced Solid Tumors

United States
Kowa Research Institute, Inc.

Completed

Compare the Pharmacokinetic of K-877 Controlled Release (CR) and Immediate Release (IR) Tablets in Healthy Adults.

Healthy

United States
Kowa Company, Ltd.

Completed

A Clinical Pharmacology Study of K-877 Controlled Release Tablet

Dyslipidemias

Japan
Kowa Research Institute, Inc.

Completed

Study to Assess the Food Effect of K-877 in Healthy Adult Volunteers

Healthy

United States
Merck Sharp & Dohme LLC

Terminated

A Study of the Safety and Efficacy of MK-3577 in Participants With Type 2 Diabetes Mellitus (MK-3577-009)

Type 2 Diabetes Mellitus
Bridge Biotherapeutics, Inc.
KCRN Research, LLC

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BBT-877 in Healthy Subjects

Idiopathic Pulmonary Fibrosis

United States
Ospedale San Raffaele

Completed

Subthreshold Laser Treatment for Reticular Pseudodrusen and Geographic Atrophy Secondary to AMD

Age-Related Macular Degeneration | Geographic Atrophy | Reticular Pseudodrusen

Italy
The Lowy Medical Research Institute Limited

Active, not recruiting

MacTel Laser Study

Macular Telangiectasia

United States
Merck Sharp & Dohme LLC

Completed

MK-8527 Single-Dose Trial in HIV-1 Infected Participants (MK-8527-004)

Human Immunodeficiency Virus

Romania, South Africa
The Eye Hospital of Wenzhou Medical University

Completed

Micropulse 577nm Laser vs Traditional Laser Treatment in Central Serous Chorioretinopathy

Central Serous Choroidopathy

China
Ospedale San Raffaele
University of Rome Tor Vergata; University of Genova; Fondazione G.B. Bietti,...

Recruiting

Subthreshold Laser Treatment for Reticular Pseudodrusen Secondary to Age-related Macular Degeneration (PASCAL-RPD)

Macular Degeneration, Dry | Macular Degeneration, Senile | Laser Burn of Retina | Macular Degeneration Intermediate

Italy
Ono Pharmaceutical Co. Ltd

Completed

Study of ONO-8577 in Patients With Overactive Bladder

Overactive Bladder

Japan
Al-Azhar University

Recruiting

A577-nm Pro -Yellow Laser In Treatment of Striae Rubra

Striae Rubra

Egypt
Kowa Research Institute, Inc.
Brigham and Women's Hospital

Terminated

Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT) (PROMINENT)

Dyslipidemia | Type2 Diabetes

United States, Spain, Canada, Hungary, Netherlands, Brazil, Bulgaria, Poland, Israel, Russian Federation, Ukraine, Denmark, Czechia, South Africa, Argentina, Mexico, United Kingdom, Romania, Germany, India, Slovakia, Japan, Colombia, ... and more
U.S. Army Medical Research and Development Command

Completed

Phase 1 Safety and Immunogenicity of Meningococcal Vaccine (HOPS)

Meningococcal Infection, Group B

United States
Merck Sharp & Dohme LLC

Completed

A Study of MK-8527 in Human Immunodeficiency Type 1 Virus (HIV-1) Infected Participants (MK-8527-002)

Human Immunodeficiency Virus | AIDS Virus

Romania
Bridge Biotherapeutics, Inc.
KCRN Research, LLC

Completed

Evaluate Safety, Pharmacokinetics and Pharmacodynamics of BBT-877 in Healthy Japanese Male

Healthy Participants

United States
HonorHealth Research Institute
Merck Sharp & Dohme LLC; Salarius Pharmaceuticals, LLC

Withdrawn

Pilot Trial of SP-2577 Plus Pembrolizumab in Select Gynecologic Cancers

Ovarian Endometrioid Adenocarcinoma | Endometrial Cancer | SCCOHT | Ovarian Clear Cell Tumor

United States
Merck Sharp & Dohme LLC

Completed

Evaluation of Safety, Tolerability, Pharmacokinetics, and Antiretroviral Activity of Ulonivirine (MK-8507) in Human Immunodeficiency Virus (HIV-1)-Infected Participants (MK-8507-003)

HIV-1 Infection
M.D. Anderson Cancer Center

Recruiting

Seclidemstat and Azacitidine for the Treatment of Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia

Myelodysplastic Syndrome | Recurrent Chronic Myelomonocytic Leukemia | Recurrent Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia-1 | Chronic Myelomonocytic Leukemia-2 | Chronic Myelomonocytic Leukemia-0

United States
Kowa Company, Ltd.

Completed

A Study of Pemafibrate in Patients With Nonalcoholic Fatty Liver Disease (NAFLD)

Non-Alcoholic Fatty Liver Disease

Japan
Kowa Research Institute, Inc.

Completed

Drug-Drug Interaction Study to Assess the Effects of Multiple-Dose Administration of K-877 on the Pharmacodynamics and the Pharmacokinetics of Multiple-Dose Administration of Warfarin in Healthy Adult Volunteers

Healthy

United States
Sun Yat-sen University

Completed

577nm Micropulse Laser vs Half-dose Photodynamic Therapy on Acute Central Serous Chorioretinopathy

Acute Central Serous Chorioretinopathy

China
Kowa Company, Ltd.

Completed

A Phase III Confirmatory Study of K-877 Extended Release Tablet

Dyslipidemias

Japan
Kowa Research Institute, Inc.

Completed

Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Mild or Moderate Renal Impairment

Severe Hypertriglyceridemia

United States, Czechia, Belarus, Hungary, Russian Federation, Poland, Bulgaria, Georgia, Ukraine
Kowa Research Institute, Inc.

Completed

Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Normal Renal Function

Severe Hypertriglyceridemia

United States, Hungary, Belarus, Bulgaria, Czechia, Georgia, Poland, Russian Federation, Ukraine
Case Comprehensive Cancer Center
National Institute on Minority Health and Health Disparities (NIMHD)

Completed

Attitudes, Beliefs, and Preferences of Older Stage I-III Breast Cancer Survivors Towards Physical Activity

Cancer Survivor | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Stage IIIC Breast Cancer

United States
The Reading Hospital and Medical Center

Completed

Educational Intervention to Increase Physician Satisfaction and Effectiveness With a New Electronic Health Record

Attitude of Health Personnel

United States
Universidad de Zaragoza

Completed

Contextual Coaching Versus Training Workshop for Assistants in Special Education.

Caregiver | Disabled Persons
VA Office of Research and Development

Completed

Multimodal Treatment of Phonological Alexia: Behavioral & fMRI Outcomes

Stroke | Aphasia | Dyslexia, Acquired

United States
Centre de Recherche de l'Institut Universitaire...

Active, not recruiting

Group Versus Individual Physiotherapy for Urinary Incontinence in Aging Women (GROUP)

Urinary Incontinence | Urinary Stress Incontinence

Canada
University of Pittsburgh
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Promoting Lifestyle Change Via Tailored mHealth Feedback to Improve Health (SMARTER)

Overweight and Obesity

United States
Oregon Health and Science University
National Cancer Institute (NCI); National Institute of Arthritis and Musculoskeletal...

Completed

Promoting Healthy Lifestyles Among Firefighters (PHLAME)

Cardiovascular Diseases | Cancer | Physical Activity | Nutrition

United States
Sun Yat-sen University

Completed

577nm Micropulse Laser Versus 532nm Subthreshold Laser Photocoagulation for Diabetic Macular Edema

Diabetic Macular Edema

China
Takeda

Available

Post Trial Access Program of TAK-577 for Von Willebrand Disease (VWD)

Von Willebrand Disease (VWD)
Biotronik SE & Co. KG

Completed

Fast VT Episodes Are Terminated by ATP One Shot (FavoriteATP)

Ventricular Tachycardia, Monomorphic

Austria, Finland, Germany, Israel
Harvard University

Completed

Couples Therapy for Alcoholic Patients (CALM)

Alcoholism

United States
Centers for Disease Control and Prevention
West Virginia University

Withdrawn

Colorectal Cancer Control in Appalachian Churches

Colorectal Cancer

United States
Case Comprehensive Cancer Center

Recruiting

Building Family Caregiver Skills Using a Simulation-Based Intervention for Care of Cancer Patients

Cancer

United States
Ege University

Enrolling by invitation

Exercise Training on Gait Pattern in Pregnancy

Pregnancy

Turkey
Ono Pharmaceutical Co. Ltd

Completed

A Study to Investigate the Effect of ONO-8539 on Acid-Induced Oesophageal Hypersensitivity in Healthy Volunteers

Acid Reflux

United Kingdom
Ono Pharmaceutical Co. Ltd

Completed

A Two-Part Study to Assess the Safety, Tolerability, PK and PD of ONO-7684 in Healthy Adult Volunteers

Venous Thromboembolism

United Kingdom
Ono Pharmaceutical Co. Ltd

Completed

Single-dose Study to Evaluate the Absolute Bioavailability and Mass Balance of ONO-5788 (ONO-5788-02)

Acromegaly

Netherlands

Search clinical trials for: ONO-8577

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