Search clinical trials for: OPT-302

Total 4771 results

Masonic Cancer Center, University of Minnesota

Recruiting

Allo HSCT Using RIC and PTCy for Hematological Diseases

Follicular Lymphoma | Myelodysplastic Syndromes | Leukemia, Myeloid | Myelofibrosis | Burkitt Lymphoma | Marginal Zone Lymphoma | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Prolymphocytic Leukemia | Plasma Cell Leukemia | Myeloproliferative Neoplasm | Small Lymphocytic... and other conditions

United States
University of British Columbia

Completed

Single Injection Adductor Canal Block vs Catheter for Total Knee Arthroplasty

Total Knee Arthroplasty
Foisor Orthopedics Clinical Hospital

Completed

Perineural Low-dose Dexamethasone Added to Infraclavicular Block Anesthesia

Postoperative Pain

Romania
Vanderbilt University Medical Center

Completed

Trial Evaluating Postop Pain and Muscle Strength Among Regional Anesthesia Techniques for Ambulatory ACL Reconstruction

Rupture of Anterior Cruciate Ligament | Tear of Anterior Cruciate Ligament

United States
University of Washington

Completed

Factors Affecting the Speed of Recovery After ACL Reconstruction

Anterior Cruciate Ligament Injury | ACL Injury | ACL - Anterior Cruciate Ligament Rupture

United States
Mansoura University

Completed

Combined Colloid Preload And Crystalloid Coload Versus Crystalloid Coload During Spinal Anesthesia for Cesarean Delivery

Cesarean Section | Anesthesia, Spinal

Egypt
University of Parma

Completed

Efficacy of Ultrasound-Guided Local Anesthetic Injection Into or Around the Sciatic Nerve for Lower Limb Anesthesia

Foot Diseases | Injuries, Knee | Orthopedic Disorders | Injuries, Leg | Injuries, Foot

Italy
National Cancer Institute (NCI)

Completed

Hormone Therapy in Preventing Endometrial Cancer in Patients With a Genetic Risk For Hereditary Nonpolyposis Colon Cancer

Endometrial Cancer

United States
AstraZeneca

Completed

Evaluation of Onset of Effect in Patients With Severe Chronic Obstructive Pulmonary Disease (COPD) Treated With Symbicort® Compared to Seretide® (SPEED)

Chronic Obstructive Pulmonary Disease (COPD)

Brazil, United Kingdom, Germany, Philippines, Denmark, Australia, Argentina, India, Belgium
Samsung Medical Center

Recruiting

Compare Efficacy of CHOP Versus Fractionated ICED in Transplant-eligible Patients With Previously Untreated PTCL

Peripheral T-cell Lymphoma

Korea, Republic of
SFJ Pharmaceuticals, Inc.
SFJ Pharmaceuticals, Inc.

Terminated

Study to Evaluate the Safety, Tolerability, PK, and PD of PB2452 With and Without Ticagrelor Pretreatment in Chinese Healthy Volunteers

Healthy

China
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

An Investigation Of The Absorption And Pharmacokinetics Of A Single Dose Of A Controlled Release (CR) Pregabalin Tablet Following Various Sized Lunches As Compared To A Single Dose Of The Immediate Release (IR) Pregabalin Capsule In Healthy Volunteers

Healthy

United States
Helsinki University Central Hospital

Completed

Patient-controlled Sedation With Propofol and Remifentanyl for Endoscopic Retrograde Cholangiopancreatography (ERCP)

Endoscopic Retrograde Cholangiopancreatography

Finland
University of Washington
National Cancer Institute (NCI)

Terminated

Carfilzomib With or Without Rituximab in the Treatment of Waldenstrom Macroglobulinemia or Marginal Zone Lymphoma

Recurrent Marginal Zone Lymphoma | Waldenstrom Macroglobulinemia | Marginal Zone Lymphoma | Refractory Marginal Zone Lymphoma | Recurrent Waldenstrom Macroglobulinemia | Refractory Waldenstrom Macroglobulinemia

United States
University of California, San Diego
Merck Sharp & Dohme LLC

Terminated

Raltegravir Cerebrospinal Fluid Pharmacodynamic Study in HIV-Infected Individuals

HIV

United States
Janssen Scientific Affairs, LLC
Bausch Health Americas, Inc.; Cipher Pharmaceuticals Inc.

Completed

Study to Evaluate the Effects of Tramadol Hydrochloride on Cardiac Repolarization in Healthy Participants

Healthy

United States
Bristol-Myers Squibb

Completed

Ph II Trial of a Novel Anti-angiogenic Agent in Combination With Chemotherapy for the Second-line Treatment of Metastatic Colorectal Cancer

Colorectal Cancer (CRC)

United States, Argentina, Italy
US Department of Veterans Affairs

Completed

Effect of Antidepressants on Back Pain

Back Pain | Sciatica

United States
Therapeutic Advances in Childhood Leukemia Consortium
Enzon Pharmaceuticals, Inc.

Terminated

EZN-3042 Administered With Re-induction Chemotherapy in Children With Relapsed Acute Lymphoblastic Leukemia (ALL)

Lymphoblastic Leukemia, Acute, Childhood | Leukemia, Lymphoblastic, Acute | Lymphoblastic Leukemia, Acute | Leukemia, Lymphoblastic, Acute, T Cell

United States, Australia
Wayne State University

Recruiting

Serratus Anterior Plane Block With and Without Adjuvants in Video-assisted Thoracoscopy

Post Operative Pain, Acute

United States
Wayne State University

Recruiting

Are Superficial Parasternal Intercostal Plane (SPIP) Blocks With Bupivacaine and With or Without Adjuvants Helpful for Post-operative Pain After Coronary Artery Bypass Grafting?

Post-operative Pain Management

United States
Astellas Institute for Regenerative Medicine

Recruiting

A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular Degeneration

Age-Related Macular Degeneration

United States
Organon and Co

Terminated

Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring and Levonorgestrel-Ethinyl Estradiol Combined Oral Contraceptive in Adult Women at Risk for Pregnancy (MK-8342B-062)

Contraception

South Africa, Austria, Costa Rica, Denmark, Finland, Germany, Hungary, Italy, Mexico, Netherlands, Norway, Peru, Poland, Sweden
M.D. Anderson Cancer Center

Active, not recruiting

Pegloticase for the Reduction of Uric Acid in Patients With Tumor Lysis Syndrome

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Tumor Lysis Syndrome

United States
Masonic Cancer Center, University of Minnesota

Active, not recruiting

Trial Evaluating MGTA-456 in Patients With High-Risk Malignancy

Acute Myeloid Leukemia | Hodgkin Lymphoma | Burkitt Lymphoma | Mantle Cell Lymphoma | Lymphoplasmacytic Lymphoma | Acute Lymphocytic Leukemia | Chronic Myelogenous Leukemia | Myelodysplasia | Relapsed T-Cell Lymphoma | Relapsed Large Cell Lymphoma | Biphenotypic/Undifferentiated Leukemia

United States
AstraZeneca
Iqvia Pty Ltd; Premier Inc.

Withdrawn

IKANOS: Breztri Maintenance Versus Any Non-Triple Inhaled Therapy After Hospitalization for a COPD Exacerbation in the US (IKANOS)

COPD

United States
Rush University Medical Center

Withdrawn

Efficacy of Intraoperative Injections on Postoperative Pain Control During Total Hip Replacement

Osteoarthritis | Degenerative Joint Disease

United States
Organon and Co

Terminated

Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring (MK-8342B) in Women With Primary Dysmenorrhea (With Optional Extension) (MK-8342B-059)

Moderate to Severe Primary Dysmenorrhea
Loxo Oncology, Inc.

Completed

Study of the Effects of Itraconazole and Rifampin on LOXO-305 in Healthy Participants

Healthy Volunteers

United States
Vejle Hospital

Terminated

Tocotrienol as a Nutritional Supplement in Patients With Advanced Lung Cancer (Toco-Pulm)

Lung Cancer

Denmark
National Institute of Diabetes and Digestive and...
The Cleveland Clinic

Completed

African American Study of Kidney Disease and Hypertension (AASK)

Hypertensive Nephrosclerosis | Chronic Renal Insufficiency
University of Vermont

Unknown

Addition of Clonidine to Ropivacaine in Adductor Canal Block

Postoperative Pain

United States
National Cancer Institute (NCI)

Completed

Akt Inhibitor MK2206, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Chronic Lymphocytic Leukemia | Recurrent Small Lymphocytic Lymphoma | Refractory Chronic Lymphocytic Leukemia

United States
GlaxoSmithKline

Completed

A Non-inferiority Study to Evaluate Efficacy, Safety and Tolerability of NEUMOTEROL® 400 and SYMBICORT® Forte in Adults With Asthma

Asthma

Argentina
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Melphalan and Amifostine Followed By One or Two Autologous or Syngeneic Stem Cell Transplants and Maintenance Therapy in Treating Patients With Stage II-III Multiple Myeloma

Stage II Multiple Myeloma | Stage III Multiple Myeloma | Refractory Multiple Myeloma

United States
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC

Completed

SAHA + CHOP in Untreated T-cell Non-Hodgkin's Lymphoma

Lymphoma

United States
Zhujiang Hospital

Unknown

Effect of Induction and Maintenance of Anesthesia With Etomidate on Hemodynamics and Oxidative Stress in Diabetic Patients

Oxidative Stress | Anesthesia | Hemodynamics
National Cancer Institute (NCI)

Completed

PS-341 Alone and PS-341 Plus EPOCH Chemotherapy to Treat Non-Hodgkin's Lymphoma

B-Cell Lymphoma

United States
National Cancer Institute (NCI)

Completed

Methoxyamine Hydrochloride, Pemetrexed Disodium, Cisplatin, and Radiation Therapy in Treating Patients With Stage IIIA-IV Non-small Cell Lung Cancer

Stage IIIA Lung Non-Small Cell Cancer AJCC v7 | Stage IIIB Lung Non-Small Cell Cancer AJCC v7 | Stage IV Lung Non-Small Cell Cancer AJCC v7 | Stage III Lung Non-Small Cell Cancer AJCC v7 | Locally Advanced Lung Non-Squamous Non-Small Cell Carcinoma | Stage III Lung Adenocarcinoma AJCC v7 | Stage... and other conditions

United States
Stanford University

Completed

Transversus Abdominis Plane Block in Microsurgical Breast Recon w/Abdominal Free Flap in Breast CA

Breast - Female

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Comparison of Two Combination Chemotherapy Regimens in Treating Patients With Extensive-Stage Small Cell Lung Cancer

Extensive Stage Small Cell Lung Cancer

United States
Case Comprehensive Cancer Center

Completed

Targeted Marrow Irradiation, Fludarabine Phosphate, and Busulfan Before Donor Progenitor Cell Transplant in Treating Patients With Hematologic Malignancies

Acute Myeloid Leukemia | Multiple Myeloma | Hodgkin Lymphoma | Myelofibrosis | Chronic Lymphocytic Leukemia | Non Hodgkin Lymphoma | Chronic Myeloid Leukemia | Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Hematologic Malignancies | Myeloproliferative Syndrome

United States
National Cancer Institute (NCI)
Eastern Cooperative Oncology Group

Completed

Comparison of Combination Chemotherapy Regimens With or Without Cetuximab in Treating Patients Who Have Undergone Surgery For Stage III Colon Cancer

Stage III Colon Cancer | Adenocarcinoma of the Colon

United States, Canada, Puerto Rico
South East Asia Research Collaboration with Hawaii
The Thai Red Cross AIDS Research Centre; Cooper Human Systems

Completed

Efficacy of VHM After Treatment Interruption in Subjects Initiating ART During Acute HIV Infection

Acute HIV Infection

Thailand
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers

Metastatic Small Intestinal Adenocarcinoma | Stage III Small Intestinal Adenocarcinoma AJCC v8 | Stage IIIA Small Intestinal Adenocarcinoma AJCC v8 | Stage IIIB Small Intestinal Adenocarcinoma AJCC v8 | Stage IV Small Intestinal Adenocarcinoma AJCC v8

United States
National Cancer Institute (NCI)

Completed

Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors

Pineoblastoma | Recurrent Medulloblastoma | Refractory Medulloblastoma | Refractory Peripheral Primitive Neuroectodermal Tumor | Central Nervous System Neoplasm | Recurrent Primitive Neuroectodermal Tumor

United States, Canada, Puerto Rico, Australia, New Zealand
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma

Rhabdomyosarcoma | Alveolar Rhabdomyosarcoma | Embryonal Rhabdomyosarcoma | Botryoid-Type Embryonal Rhabdomyosarcoma | Sclerosing Rhabdomyosarcoma | Spindle Cell Rhabdomyosarcoma

United States, Canada, Puerto Rico, Australia, New Zealand
Beth Israel Deaconess Medical Center

Recruiting

Perioperative Multimodal General AnesTHesia Focusing on Specific CNS Targets in Patients Undergoing carDiac surgERies (PATHFINDERII)

Pain | Postoperative Delirium | Neurocognitive Dysfunction | Hemodynamic Instability

United States
Endo Pharmaceuticals

Completed

A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions

Carpal Tunnel Syndrome | Complex Regional Pain Syndrome | Peripheral Neuropathy | Diabetic Neuropathy | Postherpetic Neuralgia | HIV Neuropathy | Idiopathic Sensory Neuropathy

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Daratumumab After Stem Cell Transplant in Treating Patients With Multiple Myeloma

Plasma Cell Myeloma | Secondary Amyloidosis

United States

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