Search clinical trials for: ORB-011

Total 9066 results

Orionis Biosciences Inc

Recruiting

ORB-011 In Patients With Advanced Solid Tumors (ORB)

Advanced Solid Cancer

United States
National Cancer Institute (NCI)

Completed

Anti-PD-L1/TGF-beta Trap (M7824) Alone and in Combination With TriAd Vaccine and N-803 for Resectable Head and Neck Squamous Cell Carcinoma Not Associated With Human Papillomavirus Infection

Head and Neck Cancer | Head and Neck Neoplasms

United States
Patagonia Pharmaceuticals, LLC

Completed

A Safety and Tolerability Study of Topical PAT-001 in Congenital Ichthyosis

Congenital Ichthyosis

United States
Pendulum Therapeutics

Completed

Placebo-Controlled Clinical Nutrition Study of the Safety and Metabolic Effects of Two Medical Foods in Type 2 Diabetes

Type 2 Diabetes Mellitus

United States
TR Therapeutics

Completed

Efficacy Study of GLYC-101 to Evaluate Outcomes After Laser Ablation

Wounds

United States
Acceleron Pharma Inc. (a wholly owned subsidiary...

Completed

A Safety, Tolerability and Pharmacodynamics Study of ACE-011 (ActRIIA-IgG1) in Healthy Postmenopausal Women

Osteoporosis

United States
National Cancer Institute (NCI)

Completed

Multi-Targeted Recombinant Ad5 (CEA/MUC1/Brachyury) Based Immunotherapy Vaccine Regimen in People With Advanced Cancer

Neoplasms | Breast Cancer | Lung Cancer | Prostate Cancer | Colon Cancer

United States
Achieve Life Sciences

Completed

A Study of OGX-011/Gemcitabine/Platinum-Based Regimen in Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC)

Non-small Cell Lung Cancer

United States, Canada
University of North Carolina, Chapel Hill

Completed

Analysis of Orthodontic Tooth Movement Using 3D Imaging

Malocclusion | Tooth Crowding | Dental Crowding

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Withdrawn

Study Evaluating Orally Administered ERB-041 in Subjects With Active Interstitial Cystitis

Cystitis, Interstitial

United States, Austria, Germany
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study to Evaluate Multiple Doses of ERB-041 in Healthy, Female Japanese Subjects

Healthy

Japan
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating ERB-041 in Endometriosis in Reproductive-Age Women

Endometriosis

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating ERB-041 in Active Crohn's Disease

Crohn's Disease
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety and Efficacy of ERB-041 on Reduction of Symptoms Associated With Endometriosis in Reproductive-Aged Women

Endometriosis | Dysmenorrhea | Pelvic Pain | Dyspareunia

Hong Kong, United States, Canada, Australia, United Kingdom, South Africa, Belgium
Celgene

Terminated

Study to Determine the Safety and Tolerability of Sotatercept (ACE-011) in Adults With Beta( β)- Thalassemia.

Beta Thalassemia Intermedia | Beta Thalassemia Major

France, United Kingdom, Italy, Greece
National Cancer Institute (NCI)

Completed

Treatment of Castration Resistant Prostate Cancer Using Multi-Targeted Recombinant Ad5 PSA/MUC1/Brachyury Based Immunotherapy Vaccines

Prostatic Neoplasms | Prostatic Cancer

United States
Hutchison Medipharma Limited

Completed

Phase I Clinical Trial in Healthy Male Volunteers

Inflammatory Bowel Diseases
Nexel Co., Ltd.
Novotech (Australia) Pty Limited

Completed

A Study of NP-011 in Healthy Volunteers

Myocardial Infarction

Australia
AbbVie

Completed

A Study of ABBV-011 Alone and in Combination With Budigalimab (ABBV-181) in Participants With Relapsed or Refractory Small Cell Lung Cancer

Small Cell Lung Cancer

United States, Japan, Korea, Republic of, Taiwan
Prolacta Bioscience

Recruiting

Study To Evaluate The Safety And Efficacy of PBCLN-010 In Combination With PBCLN-014 in Participants Receiving Allogeneic Hematopoietic Cell Transplantation

Hematologic Malignancy

United States
Guangzhou Gloria Biosciences Co., Ltd.

Recruiting

Immuno-Oncology Drugs GLS-012 Alone & in Combination GLS-010 Treating With Advanced Patients Solid Tumors

Solid Tumor

China
Cryonove Pharma
CEISO; Dermatech; LTD HEALTH

Completed

Tolerance and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots

Lentigo Solar

Georgia
Celgene
Celgene Corporation

Terminated

A Phase 1 Trial of ABI-011 in Patients With Advanced Solid Tumors or Lymphomas

Advanced Solid Tumors

United States
Cryonove Pharma
CEISO; Dermatech; Sefako Makgatho Health Sciences University

Completed

Tolerance and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots.

Solar Lentigo | Post-inflammatory Hyperpigmentation | Senile Lentigo

South Africa
Aura Biosciences

Recruiting

A Phase 1, Open-label Trial of Belzupacap Sarotalocan (AU-011) in Bladder Cancer

Muscle-Invasive Bladder Carcinoma | Non-muscle-invasive Bladder Cancer

United States
Fochon Pharmaceuticals, Ltd.

Recruiting

Study of FCN-011 in Patients With Advanced Solid Tumor（Phase I）and NTRK Fusion Positive Advanced Solid Tumor （Phase II）

Advanced Solid Tumor

China
University of British Columbia
United States Department of Defense

Completed

Study of OGX-011 Given Prior to Radical Prostatectomy in Patients With Localized Prostate Cancer

Prostate Cancer

Canada
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Sotatercept in Treating Patients With Myeloproliferative Neoplasm-Associated Myelofibrosis or Anemia

Anemia | Myelofibrosis | Myelodysplastic/Myeloproliferative Neoplasm

United States
Ornovi, Inc.

Withdrawn

A First in Human Single and Multiple Ascending Dose and Open Label Food Effect Study of OR-101 in Healthy Subjects

Alopecia Areata

Australia
Heron Therapeutics

Completed

A Pilot Study to Investigate the Safety, Efficacy, Pharmacokinetics and Bioavailability of HTX-011, HTX-002, or HTX-009 Administered Via Injection and/or Topical Application Following Unilateral Open Inguinal Herniorrhaphy

Postoperative Pain

United States
PurGenesis Technologies Inc.

Completed

A Study to Assess the Safety and Tolerability of PUR 0110 Rectal Enema in Normal Healthy Volunteers

Ulcerative Colitis

Germany
Allorion Therapeutics Inc

Recruiting

Safety and Pharmacokinetic Study of ARTS-011 in Chinese Healthy Volunteers

Chinese Healthy Volunteer

China
Merck Sharp & Dohme LLC

Terminated

Study to Evaluate Effect of a Single Dose of Sotatercept (ACE-011) on Red Blood Cell Mass and Plasma Volume in Participants With Solid Tumors

Solid Tumors

United States
Celgene

No longer available

Expanded Access for ACE-011

Myelodysplastic Syndrome

United States
Celgene

Completed

A Phase 2 Study of Intravenous or Subcutaneous Dosing of Sotatercept (ACE-011) in Patients With End-Stage Kidney Disease on Hemodialysis

Anemia | Kidney Failure, Chronic

Belgium, Spain, United Kingdom, Portugal, Germany
Achieve Life Sciences

Unknown

A Multinational, Randomized, Open-Label Study of Custirsen In Patients With Advanced or Metastatic (Stage IV) Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer

Taiwan, Spain, Israel, Italy, Korea, Republic of, New Zealand, Australia, Germany, United States, Hungary, Poland, Russian Federation, Singapore, Thailand, Ukraine
Achieve Life Sciences

Completed

Evaluation of Safety and Feasibility of OGX-011 in Combination With 2nd-line Chemotherapy in Patients With HRPC

Prostate Cancer

Canada
Amgen

Completed

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Clinical Effects of AMG 811 in Subjects With Psoriasis

Psoriasis

New Zealand, Australia
Claris Biotherapeutics, Inc.

Recruiting

Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Corneal Scars

Corneal Scar

United States
Celgene
Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway...

Completed

A Phase 2a Study To Evaluate The Pharmacokinetics, Safety, Efficacy, Tolerability, And Pharmacodynamics of Sotatercept (ACE-011) for the Correction of Anemia in Subjects With End-stage Renal Disease on Hemodialysis.

Anemia

United States
Merck Sharp & Dohme LLC

Terminated

Study of Sotatercept for the Treatment of Chemotherapy Induced Anemia in Patients With Metastatic Breast Cancer (MK-7962-012)

Chemotherapy Induced Anemia

United States, Russian Federation
Abbisko Therapeutics Co, Ltd

Recruiting

A Clinical Trial to Evaluate the Relative Bioavailability of New and Old ABSK-011 Capsules

Healthy Subjects

China
Immodulon Therapeutics Ltd
Theradex; HCA International Limited

Completed

A Clinical Study, to Evaluate the Safety and Tolerability of Intradermal IMM-101 in Adult Melanoma Cancer Patients

Melanoma

United Kingdom
Cellular Biomedicine Group Ltd.
Chinese PLA General Hospital

Unknown

A Phase I Study Evaluating Safety and Efficacy of C-CAR011 Treatment in Adult Subjects With r/r CD19+B-ALL

Relapsed or Refractory Acute Lymphoblastic Leukemia

China
Guangzhou Gloria Biosciences Co., Ltd.

Not yet recruiting

Safety, Tolerability, and Efficacy of GLS-012 and GLS-010 in Patients With Advanced Non-Small Cell Lung Cancer

Advanced Non-Small Cell Lung Cancer

China
Shanghai Synergy Pharmaceutical Sciences Co., Ltd.

Not yet recruiting

Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamic Characteristics of HHT120 in Healthy Subjects (HHT120)

Healthy

China
Celgene

Completed

A Safety, Tolerability and Efficacy Study of ACE-011 in Patients With Osteolytic Lesions of Multiple Myeloma

Multiple Myeloma

Russian Federation
Claris Biotherapeutics, Inc.

Recruiting

Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Neurotrophic Keratitis Subjects

Neurotrophic Keratitis

United States, Canada
Acceleron Pharma, Inc., a wholly-owned subsidiary...

Recruiting

A Long-term Follow-up Study of Sotatercept for PAH Treatment (MK-7962-004/A011-12) (SOTERIA)

Pulmonary Arterial Hypertension | PAH

United States, France, Germany, Spain, Sweden, Argentina, Australia, Austria, Colombia, Croatia, Denmark, Greece, Israel, Italy, Korea, Republic of, Netherlands, New Zealand, Portugal, Serbia, Taiwan, United Kingdom, Brazil, Canada, B... and more
Cellular Biomedicine Group Ltd.
The First Affiliated Hospital with Nanjing Medical University

Completed

A Phase 1 Study Evaluating Safety and Efficacy of C-CAR011 Treatment in DLBCL Subjects (C-CAR011)

Refractory Diffuse Large B-Cell Lymphoma

China

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