Search clinical trials for: Palomid 529

Total 803 results

Paloma Pharmaceuticals, Inc.

Completed

Phase I Study of Palomid 529 a Dual TORC1/2 Inhibitor of the PI3K/Akt/mTOR Pathway for Advanced Neovascular Age-Related Macular Degeneration (P52901)

Age-Related Macular Degeneration

United States
National Eye Institute (NEI)

Completed

Palomid 529 in Patients With Neovascular Age-Related Macular Degeneration

Age-Related Macular Degeneration

United States
YourChoice Therapeutics, Inc.

Recruiting

First in Human Study Evaluating Single Ascending Oral Doses of YCT-529 in Healthy Males

Male Contraception

United Kingdom
Valentis

Completed

Trial of VLTS-589 in Subjects With Intermittent Claudication

Intermittent Claudication | Peripheral Vascular Disease

United States
University of Nottingham
University Hospitals of Derby and Burton NHS Foundation Trust

Completed

A Study of Agreement Between Oxygen Saturation Measured by Two Probes in Infants on the Neonatal Unit (Ag-OS)

Neonatal Disease

United Kingdom
Amgen

Completed

AMG 529 First in Human Study

Cardiovascular

United States
Immuron Ltd.

Terminated

Treatment for Clostridium-difficile Infection With IMM529

Clostridium Difficile Infection | Clostridium Difficile Infection Recurrence

Israel
Beijing Chao Yang Hospital

Not yet recruiting

A Registry Study of Patients Hospitalized With Confirmed COVID-19

COVID-19
Hutchmed

Active, not recruiting

Human Mass Balance of [14C]HMPL-523 in Healthy Adult Male Chinese Subjects

Imumune Thrombocytopenia(ITP) Human Mass Balance

China
Huashan Hospital

Recruiting

A Real World Study of Paxlovid for the Treatment of Hospitalized Patients Confirmed With COVID-19

COVID-19

China
Hutchison Medipharma Limited

Completed

A Study of the Safety, Tolerability and Pharmacokinetics of HMPL-523

Rheumatoid Arthritis (RA)

Australia
Alkermes, Inc.
QPS Netherlands B.V.

Completed

Single and Multiple Ascending Dose and Food Effect PK Study in Healthy Adult and Elderly Subjects

Healthy

Netherlands
Copenhagen University Hospital at Herlev

Terminated

Gene Electrotransfer to Muscle With Plasmid AMEP in Patients With Disseminated Cancer

Metastatic Malignant Neoplasm

Denmark
Hutchison Medipharma Limited

Unknown

A Study of Hutchison MediPharma Limited(HMPL)-523 in Patients With Relapsed or Refractory Mature B-cell Neoplasms

Mature B-cell Neoplasms

China
Helsinki University Central Hospital

Completed

Complications in Parotid Surgery

Facial Palsy
Aragon Pharmaceuticals, Inc.

Active, not recruiting

Safety, Pharmacokinetic and Proof-of-Concept Study of ARN-509 (Apalutamide) in Castration-Resistant Prostate Cancer (CRPC)

Prostate Cancer

United States
Hutchison Medipharma Limited
Iqvia Pty Ltd

Unknown

A Study of HMPL-523 in Relapsed or Refractory Hematologic Malignancies

Hematologic Malignancies

Australia
Zeria Pharmaceutical

Completed

Therapeutic Use of Oral Sodium Phosphate (Z-521) in Primary Hypophosphatemic Rickets

Primary Hypophosphatemic Rickets

Japan
Aragon Pharmaceuticals, Inc.

Completed

14C-ARN-509 Microtracer Label AME and Absolute BA Study

Healthy

Netherlands
Takeda

Terminated

Safety Study of TAK-559 in Treating Subjects With Type 2 Diabetes Mellitus

Diabetes Mellitus
Sangamo Therapeutics

Completed

Clinical Trial of SB-509 in Subjects With Amyotrophic Lateral Sclerosis (ALS) (ALS)

Amyotrophic Lateral Sclerosis

United States
Ono Pharma USA Inc

Completed

Pilot Study of ONO-5129 in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

Japan
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of MYO-029

Healthy
Atea Pharmaceuticals, Inc.

Completed

Study of AT-527 in Healthy Subjects Under Fasting Conditions or With a Meal

Healthy Volunteer Study

Canada
MedImmune LLC

Completed

Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Single-Dose Subcutaneous Administration of MEDI-528

Healthy

United States
Rigshospitalet, Denmark

Completed

The Effect of Mobilized Stem Cell by G-CSF and VEGF Gene Therapy in Patients With Stable Severe Angina Pectoris

Ischemic Heart Disease

Denmark
Chong Kun Dang Pharmaceutical

Completed

Study to Investigate the Effects of Food on the Pharmacokinetics/Pharmacodynamics of CKD-519

Healthy Volunteers

Korea, Republic of
Dong-A ST Co., Ltd.

Recruiting

Clinical Trial to Evaluate the Efficacy and Safety of DA-5219 in Patients With Acute or Chronic Gastritis

Gastritis Acute | Gastritis Chronic

Korea, Republic of
Vertex Pharmaceuticals Incorporated

Completed

A Magnetic Resonance Imaging Study and Arthroscopic Biopsy Substudy in Subjects With Active Rheumatoid Arthritis Receiving VX-509, an Oral JAK3 Inhibitor

Rheumatoid Arthritis

United States, Denmark, Estonia, Lithuania, Netherlands, South Africa
Johns Hopkins University
National Institute of Mental Health (NIMH)

Recruiting

Improving Screening and Follow Up for Suicidal Ideation and Behaviors Among Latinx Youth in Primary Care (PALOMA)

Suicidal Ideation

United States
Atea Pharmaceuticals, Inc.
Hoffmann-La Roche

Completed

Study of AT-527 in Healthy Subjects (R07496998)

Healthy Volunteer Study

Canada
AnGes USA, Inc.

Completed

Study of HGF Via Plasmid Vector to Improve Perfusion in Critical Limb Ischemia

Ischemia | Peripheral Vascular Disease | Arterial Occlusive Disease

United States
NS Pharma, Inc.
Nippon Shinyaku Co., Ltd.

Recruiting

Trial of Efficacy and Safety of NS-229 Versus Placebo in Patients With Eosinophilic Granulomatosis With Polyangiitis

Churg-Strauss Syndrome | Eosinophilic Granulomatosis With Polyangiitis

United States, Japan
Kura Oncology, Inc.

Recruiting

First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia | Acute Leukemia of Ambiguous Lineage | Advanced Malignant Neoplasm | Mixed Phenotype Acute Leukemia | Mixed Lineage Leukemia | Mixed Lineage Acute Leukemia

United States, Spain, United Kingdom, France, Germany, Canada, Belgium, Italy
Atea Pharmaceuticals, Inc.

Terminated

Safety and Efficacy of AT-527 in Subjects With Moderate Coronavirus Disease (COVID-19) in a Hospital Setting

COVID-19

United States, Argentina, Belgium, Brazil, Egypt, Moldova, Republic of, Romania, South Africa, Spain, Ukraine
Aldeyra Therapeutics, Inc.

Completed

A Double Masked, Placebo Controlled, Single Center, Randomized Clinical Trial to Assess the Safety and Efficacy of Subjects With Mild Asthma Induced by the Bronchial Allergen Challenge (BAC)

Atopic Asthma

Canada
Boston Pharmaceuticals

Completed

Study to Evaluate the Efficacy, Safety, and Tolerability of BOS-589 in the Treatment of Patients With Diarrhea-predominant Irritable Bowel Syndrome (IBS-D)

Diarrhea-predominant Irritable Bowel Syndrome

United States
Chong Kun Dang Pharmaceutical

Completed

Study to Investigate the Safety/Tolerability and Pharmacokinetics/Pharmacodynamics of CKD-519

Dyslipidemia

Korea, Republic of
Arrowhead Pharmaceuticals

Completed

Safety and Tolerability Study of ARC-520 in Healthy Volunteers

Healthy

Australia
Takeda

Terminated

Efficacy and Safety Study of TAK-559 in Treating Subjects With Type 2 Diabetes Mellitus

Diabetes Mellitus
Amgen

Terminated

First-in-Human Study to Evaluate AMG 579 in Healthy Subjects and Patients With Stable Schizophrenia

Schizophrenia

United States
Hallux, Inc.

Completed

Efficacy, Safety, and Tolerability of HTS-519 Insert in Patients With Toenail Fungus of the Big Toenail

Onychomycosis

United States
AbbVie

Recruiting

Study to Evaluate Adverse Events and Change in Disease Activity in Adult Participants With B-Cell Malignancies Receiving Oral ABBV-525 Tablets

Diffuse Large B-Cell Lymphoma | Non-Hodgkin's Lymphoma | Chronic Lymphocytic Leukemia | B Cell Malignancies

United States, Israel, Australia, France, United Kingdom, Belgium, Spain
Children's Hospital Medical Center, Cincinnati
National Institutes of Health (NIH)

Recruiting

Improving Outcomes in Pediatric Obstructive Sleep Apnea With Computational Fluid Dynamics (OSA-MRI)

Obstructive Sleep Apnea

United States
Ezra Cohen
The V Foundation for Cancer Research

Recruiting

Window of Opportunity Study of IPI-549 in Patients With Locally Advanced HPV+ and HPV- Head and Neck Squamous Cell Carcinoma

Head and Neck Cancer | HPV-Related Malignancy | Head and Neck Squamous Cell Carcinoma | Head and Neck Carcinoma | HPV-Related Carcinoma | HPV-Related Squamous Cell Carcinoma | Head and Neck Cancer Stage IV | Head and Neck Cancer Stage III

United States
Hutchmed

Active, not recruiting

An Open-label, Dose Escalation Trial to Evaluate the Safety and Pharmacokinetics of HMPL-523 in Patients With Lymphoma

Non Hodgkin Lymphoma

Spain, United States, Denmark, France, Finland, Italy, Poland
Vertex Pharmaceuticals Incorporated

Completed

Single and Multiple Dose Escalation Study of VX-509 in Healthy Subjects

Healthy

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating AGG-523 in Subjects With Osteoarthritis

Osteoarthritis

United States
MedImmune LLC

Completed

Study to Evaluate the Safety, Tolerability,Immunogenicity, and Pharmacokinetics of MEDI-528 in Healthy Adult Volunteers

Asthma

United States
Chong Kun Dang Pharmaceutical

Completed

Study to Assess PK/PD Character, Safety/Tolerability of CKD-519 New Formulation in Healthy Male Subject.

Dyslipidemia

Korea, Republic of

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