Search clinical trials for: Part 2: Treatment D, RO7033877 and moxifloxacin placebo

Total 294 results

Hoffmann-La Roche

Completed

A Two-part, Single-dose, Randomized Study to Evaluate the Safety of Supra-therapeutic Doses of RO7033877 and to Investigate the Effect of RO7033877 on the QTc Interval

Healthy Volunteer

United States
AstraZeneca
Acerta Pharma, LLC

Completed

A Study to Evaluate Relative Bioavailability, Proton Pump Inhibitor (PPI) (Rabeprazole) Effect, Food Effect and Particle Size Effect of New Acalabrutinib Tablet in Healthy Subjects

Bioavailability | B-cell Lymphoid Cancer

United States
Pfizer

Completed

A Study in Normal Healthy People, Testing Different Versions of a Pill That Will be Used to Treat Rheumatoid Arthritis.

Rheumatoid Arthritis | Healthy Volunteers

United States
Hoffmann-La Roche

Completed

Study to Investigate the Effect of Balovaptan on the QTC Interval in Healthy Subjects

Healthy Volunteers

United States
Merck Sharp & Dohme LLC

Terminated

Efficacy and Safety Trial of Verubecestat (MK-8931) in Participants With Prodromal Alzheimer's Disease (MK-8931-019) (APECS)

Alzheimer's Disease | Amnestic Mild Cognitive Impairment | Prodromal Alzheimer's Disease
Janssen Cilag N.V./S.A.

Completed

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JNJ-38877618 in Healthy Male Participants

Healthy Volunteers

United Kingdom
Sun Pharmaceutical Industries Limited

Completed

Efficacy and Safety of Tildrakizumab in the Treatment of Scalp Psoriasis

Scalp Psoriasis

United States, Australia
AstraZeneca

Completed

Two-part Safety, Tolerability, Pharmacodynamic and -Kinetic Study of Inhaled AZD8871 in Asthmatic and COPD Subjects

Asthma (Part 1) | COPD (Part 2)

United Kingdom
Janssen Research & Development, LLC

Completed

A Single Ascending Dose Study in Healthy Participants and Multiple Ascending Dose Study of CNTO 7160 in Participants With Asthma and Participants With Atopic Dermatitis

Healthy | Asthma | Atopic Dermatitis

Germany, Belgium
Chiesi Farmaceutici S.p.A.

Terminated

A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of CHF6297 in Healthy Subjects and Patients With COPD (CHF6297 FIH)

Chronic Obstructive Pulmonary Disease

United Kingdom
Actimed Therapeutics Ltd
Quotient Sciences

Completed

Study of Comparative Bioavailability and Pharmacokinetics of ACM-001.1) and Pindolol in Healthy Volunteers (HV)

Cachexia

United Kingdom
Tetherex Pharmaceuticals Corporation

Completed

Study to Assess the Safety and Efficacy of SelK2 on Airway Responses Following Allergen Challenge in Subjects With Asthma (Part 1) and in Subjects With Chronic Obstructive Pulmonary Disease (Part 2)

Chronic Obstructive Pulmonary Disease | Asthma

United Kingdom
Czech Lymphoma Study Group
Hoffmann-La Roche; Ministry of Health, Czech Republic

Completed

R-MegaCHOP-ESHAP-BEAM in Patients With High-Risk Aggressive B-Cell Lymphomas (R-MCEB)

Diffuse Large B-Cell Lymphoma. | Primary Mediastinal B-Cell Lymphoma | Follicular Lymphoma Grade III

Czech Republic
Enanta Pharmaceuticals, Inc

Terminated

A 2 PART STUDY EVALUATING EDP-721 IN HEALTHY SUBJECTS AND EDP-721 IN COMBINATION WITH EDP-514 IN PATIENTS WITH CHRONIC HEPATITIS B VIRUS INFECTION.

Chronic Hepatitis B Virus Infection

New Zealand
Kanyos Bio, Inc., a wholly-owned subsidiary of...
Pfizer

Recruiting

A Study of Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of KAN-101 in Celiac Disease (ACeD-it)

Celiac Disease

United States, Australia, New Zealand
Huahui Health

Completed

A Study to Evaluate the Safety and Pharmacokinetics of HH-120 Nasal Spray in Healthy Volunteers

COVID-19

China
ViiV Healthcare
GlaxoSmithKline

Terminated

A Study to Determine the Effect of Multiple Doses of BMS-955176 on the Electrocardiograph of Healthy Subjects

Infection, Human Immunodeficiency Virus

United States
Novartis Pharmaceuticals

Recruiting

Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V

Lupus Nephritis

France, Spain, Israel, Turkey, United States, Germany, India, Hungary, Malaysia, Portugal, Brazil, China, Puerto Rico, Hong Kong, Mexico, Singapore
AstraZeneca

Completed

Study to Investigate Safety, Tolerability and Pharmacokinetics of AZD2423 Multiple Doses in Healthy Volunteers

Healthy

United Kingdom
Pfizer

Completed

Study To Assess The Bioequivalence Under Fed And Fasted Conditions Of The Fesoterodine Beads-In-Capsule SR4 And SR7 Formulations And To Estimate The Bioavailability of SR7 Beads Sprinkled On Apple Sauce Relative To The Beads-In-Capsule SR7 Formulation Administer

Neurogenic Detrusor Overactivity

Belgium
Janssen R&D Ireland

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of GSK2336805 Alone and With the Co-administration of TMC435 in Healthy Japanese Participants.

Healthy

United States
Food and Drug Administration (FDA)
Spaulding Clinical Research LLC

Completed

Electrophysiological Effects of Potential QT Prolonging Drugs

Pharmacokinetics | Pharmacodynamics | Drug-induced QT Prolongation

United States
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Terminated

Clinical Study of Liposomal Mitoxantrone Hydrochloride Injection Combined With Pegaspargase in the Treatment of NKTCL

Extranodal NK/T-cell Lymphoma, Nasal Type

China
IlDong Pharmaceutical Co Ltd

Recruiting

IDG-16177 for the Evaluation of Its Safety and Pharmacokinetics

Type 2 Diabetes

Germany
GangaGen, Inc.

Completed

Safety & Efficacy of an Antibacterial Protein Molecule Applied Topically to the Nostrils of Volunteers and Patients

Bacterial Infections | Infectious Disease

Singapore
Omeros Corporation

Terminated

Intraoperative Floppy Iris Syndrome Undergoing Intraocular Lens Replacement Surgery

Intraocular Lens Replacement | Intraoperative Floppy Iris Syndrome

Austria, Germany
Tetraphase Pharmaceuticals, Inc.

Completed

A Thorough QT/QTc Study to Evaluate the Effects of an Intravenous Infusion of Eravacycline (TP-434) on Cardiac Repolarization

Normal Healthy Subjects
Entasis Therapeutics

Completed

Study Evaluating the Effect of ETX2514 on Cardiac Repolarization in Healthy Male or Female Volunteers

Acinetobacter Baumannii-calcoaceticus Complex Infections

United States
USDA, Western Human Nutrition Research Center

Completed

Assessment of Vitamin D Supplementation and Immune Function (FL-82)

Vitamin D Deficiency

United States
Trevena Inc.

Terminated

A Trial to Evaluate the Efficacy, Safety and Tolerability of Subcutaneous TRV250

Migraines

United Kingdom
U.S. Army Medical Research and Development Command
National Institutes of Health (NIH); Mahidol University

Completed

Safety and Efficacy Study of WRSS1, a Shigella Sonnei Vaccine Candidate

Diarrhea | Dysentery | Shigella

Thailand
Sunovion

Completed

A Clinical Study to Investigate the Effect of an Investigational Drug on Electrocardiogram Intervals in Adults With Schizophrenia.

Schizophrenia

United States
Novartis Pharmaceuticals

Completed

Cardiac Safety of Indacaterol

Chronic Obstructive Pulmonary Disease | Healthy Volunteers

United States
Organon and Co

Completed

Etoricoxib in the Treatment of Osteoarthritis (MK-0663-007)

Osteoarthritis
AstraZeneca

Recruiting

Zibotentan and Dapagliflozin Combination, EvAluated in Liver Cirrhosis (ZEAL Study) (ZEAL)

Liver Cirrhosis

Spain, Denmark, Germany, United States, China, Australia, Belgium, Netherlands, Switzerland, Austria, Taiwan, Canada, Czechia
Nathan Kline Institute for Psychiatric Research
National Institute of Mental Health (NIMH); Yale University; The Zucker Hillside...

Completed

D-serine for the Schizophrenia Prodrome

Schizophrenia Prodrome

United States
Bayer

Completed

Study to Assess the Safety of BAY1067197 in Stable Heart Failure Patients on Standard Therapy Including ß-blocker

Heart Failure

Netherlands
Organon and Co

Completed

A Two-Part 26-Week Study of Etoricoxib as Treatment for Ankylosing Spondylitis (AS) (MK-0663-108)

Spondylitis, Ankylosing
Zydus Therapeutics Inc.

Completed

A Study to Evaluate the Effect of Saroglitazar Magnesium on the QTc Interval in Healthy Volunteers

Healthy

India
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effects of Domperidone on Cardiac Repolarization in Healthy Volunteers

Healthy

Belgium
Chiesi Farmaceutici S.p.A.
Quintiles, Inc.

Completed

Pharmacokinetic Interaction and the Safety of Inhaled CHF5259 and CHF6001

Copd

United Kingdom
GlaxoSmithKline

Completed

A Study to Evaluate the Effect of Intravenous Zanamivir on Cardiac Conduction in Healthy Volunteers

Influenza, Human

United States
Galera Therapeutics, Inc.
Syneos Health

Completed

A Phase 1, Randomized, Placebo-and Positive-Controlled Crossover Study to Determine the Effect of Single-Dose GC4419 on QTc Interval in Healthy Volunteers

Healthy | Healthy Volunteers

Australia
Bayer

Completed

Study to Gather Information on the Influence of BAY1817080 on the Electrical Activity of the Heart Recorded by an Electrocardiogram in Healthy Male and Female Participants

Overactive Bladder | Cough | Endometriosis

Germany
Kythera Biopharmaceuticals

Completed

Evaluation of the Effect of ATX-101 on QT/QTc Intervals (ATX-101-11-24)

Healthy

United States
MedDay Pharmaceuticals SA
Parexel; ERT: Clinical Trial Technology Solutions

Unknown

TQT2 Study to Evaluate the Effect of MD1003 on Cardiac Repolarization in Healthy Adult Subjects (TQT2)

Healthy Volunteers

United Kingdom
US Department of Veterans Affairs

Completed

Improving Stroke Rehabilitation: Spacing Effect and D-cycloserine

Stroke

United States
TaiGen Biotechnology Co., Ltd.

Completed

A Study Evaluating the Effect of a Single-dose Oral Administration of Nemonoxacin Capsule on QTc Intervals and Heart Rhythms of Healthy Subjects and the Influence of Food Intake on QTc Intervals and Pharmacokinetic Characteristics

Healthy Volunteers
NorthSea Therapeutics B.V.

Completed

A Study to Evaluate the Effects of NST-4016 on QT/Corrected QT (QTc) Interval

Dyslipidemias

United Kingdom
Novo Nordisk A/S

Completed

Effect of Liraglutide on Heart Frequency in Healthy Volunteers

Diabetes Mellitus, Type 2 | Diabetes

United States

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